Kadir Atakır, Kaan Işın, Abdullah Taş, Hakan Önder
{"title":"Diagnostic accuracy and consistency of ChatGPT-4o in radiology: influence of image, clinical data, and answer options on performance.","authors":"Kadir Atakır, Kaan Işın, Abdullah Taş, Hakan Önder","doi":"10.4274/dir.2025.253460","DOIUrl":"https://doi.org/10.4274/dir.2025.253460","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the diagnostic accuracy of Chat Generative Pre-trained Transformer (ChatGPT) version 4 Omni (ChatGPT-4o) in radiology across seven information input combinations (image, clinical data, and multiple-choice options) to assess the consistency of its outputs across repeated trials and to compare its performance with that of human radiologists.</p><p><strong>Methods: </strong>We tested 129 distinct radiology cases under seven input conditions (varying presence of imaging, clinical context, and answer options). Each case was processed by ChatGPT-4o for seven different input combinations on three separate accounts. Diagnostic accuracy was determined by comparison with ground-truth diagnoses, and interobserver consistency was measured using Fleiss' kappa. Pairwise comparisons were performed with the Wilcoxon signed-rank test. Additionally, the same set of cases was evaluated by nine radiology residents to benchmark ChatGPT-4o's performance against human diagnostic accuracy.</p><p><strong>Results: </strong>ChatGPT-4o's diagnostic accuracy was lowest for \"image only\" (19.90%) and \"options only\" (20.67%) conditions. The highest accuracy was observed in \"image + clinical information + options\" (80.88%) and \"clinical information + options\" (75.45%) conditions. The highest interobserver agreement was observed in the \"image + clinical information + options\" condition (κ = 0.733) and the lowest was in the \"options only\" condition (κ = 0.023), suggesting that more information improves consistency. However, there was no effective benefit of adding imaging data over already provided clinical data and options, as seen in post-hoc analysis. In human comparison, ChatGPT-4o outperformed radiology residents in text-based configurations (75.45% vs. 42.89%), whereas residents showed slightly better performance in image-based tasks (64.13% vs. 61.24%). Notably, when residents were allowed to use ChatGPT-4o as a support tool, their image-based diagnostic accuracy increased from 63.04% to 74.16%.</p><p><strong>Conclusion: </strong>ChatGPT-4o performs well when provided with rich textual input but remains limited in purely image- based diagnoses. Its accuracy and consistency increase with multimodal input, yet adding imaging does not significantly improve performance beyond clinical context and diagnostic options alone. The model's superior performance to residents in text-based tasks underscores its potential as a diagnostic aid in structured scenarios. Furthermore, its integration as a support tool may enhance human diagnostic accuracy, particularly in image-based interpretation.</p><p><strong>Clinical significance: </strong>Although ChatGPT-4o is not yet capable of reliably interpreting radiologic images on its own, it demonstrates strong performance in text-based diagnostic reasoning. Its integration into clinical workflows-particularly for triage, structured decision support, or educational purposes-may augment ra","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145112232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaoyu Liu, Yinzhong Wang, Caihua Xu, Yixiang Li, Junqiang Lei
{"title":"Magnetic resonance T1ρ relaxation in patients with liver fibrosis: a systematic review and meta-analysis.","authors":"Xiaoyu Liu, Yinzhong Wang, Caihua Xu, Yixiang Li, Junqiang Lei","doi":"10.4274/dir.2025.253325","DOIUrl":"https://doi.org/10.4274/dir.2025.253325","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the diagnostic performance of T1ρ relaxation in distinguishing patients with liver fibrosis (LF) from those without.</p><p><strong>Methods: </strong>A systematic review was conducted using PubMed, EMBASE, Cochrane, and Web of Science databases up to February 2025 to identify studies assessing T1ρ for LF diagnosis.</p><p><strong>Results: </strong>Eleven studies involving 792 patients were included. T1ρ values were significantly higher in cirrhotic versus normal livers [weighted mean difference (WMD): 6.69, <i>P</i> < 0.001], and in fibrotic versus normal livers (WMD: 7.17, <i>P</i> = 0.006). Patients with Child-Pugh classes A, B, and C showed significantly higher T1ρ values compared with normal liver (<i>P</i> < 0.001). T1ρ values in LF stages F1-F3 were not significantly different from normal liver (<i>P</i> = 0.18), but stage F4 showed significant differences (WMD: 10.48, <i>P</i> = 0.02).</p><p><strong>Conclusion: </strong>T1ρ relaxation differentiates high-grade LF from normal liver tissue.</p><p><strong>Clinical significance: </strong>As a non-invasive imaging technique, T1ρ shows potential for use in the diagnosis and follow-up of LF and to optimize the assessment and management of chronic liver disease.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145112217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Y Hameed, Charles A James, Kevin Wong, Paul S Lewis, Paula K Roberson, Kelli R Schmitz, Sateesh Jayappa, Amy C Rowell, Marcene McVay-Gillam, Mary B Moore
{"title":"Gastrostomy tube check radiographs: performance of an alternative diagnostic exam.","authors":"Muhammad Y Hameed, Charles A James, Kevin Wong, Paul S Lewis, Paula K Roberson, Kelli R Schmitz, Sateesh Jayappa, Amy C Rowell, Marcene McVay-Gillam, Mary B Moore","doi":"10.4274/dir.2025.253399","DOIUrl":"https://doi.org/10.4274/dir.2025.253399","url":null,"abstract":"<p><strong>Purpose: </strong>The traditional imaging exam to check a gastrostomy tube (G-tube) used fluoroscopy, which requires the presence of a radiologist. Evaluate the effectiveness of an alternative 2-view abdominal radiograph exam protocol instituted to replace the prior fluoroscopic G-tube contrast check exam and provide 24/7 coverage at 2 affiliated hospitals.</p><p><strong>Methods: </strong>An alternative 2-view G-tube check radiograph exam following stratified contrast administration was introduced at 2 affiliated children's hospitals. Gastrostomy-tube radiograph exams performed between December 2019 and May 2022 at 2 affiliated hospitals were identified, and a retrospective chart review was performed to delineate exam test yield, accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). Additional data collected included exam adherence to the protocol, 30-day adverse events, reporting time, and the years of experience of the reporting pediatric radiologist.</p><p><strong>Results: </strong>A total of 227 exams were performed among 186 patients. The 2-view radiograph protocol was followed in 81.9% (186/227). Additional radiograph views were performed for 18.1% (41/227) of cases, and additional contrast volume for 9.3% (21/227) of cases. A fluoroscopic G-tube contrast check was requested for 7 of 13 indeterminate readings with high clinical suspicion. Following the reclassification of indeterminate exams based on clinical suspicion, exam performance results were as follows: test yield, 94.3%; accuracy, 97.8%; sensitivity, 90.0%; specificity, 98.2%; PPV, 69.2%; NPV, 99.5%. The 1 false negative exam required a second hospital visit 7 days after the initial exam to detect and correct G-tube malposition. Reporting time under 1 hour occurred in 79.7% (181/227). Delayed radiology reporting in 1 patient led to endoscopic confirmation of abnormal G-tube alignment. Furthermore, 5.7% (13/227) exams were reported as indeterminate, adding a median time delay of 40 minutes (interquartile range, 90). Indeterminate exam reporting did not correlate with the years of experience of the reporting pediatric radiologist (<i>P</i> = 0.189). Reporting time over 1 hour occurred more often in the after-hours group (<i>P</i> = 0.032).</p><p><strong>Conclusion: </strong>This alternative diagnostic exam performed well in terms of high test yield, accuracy, sensitivity, specificity, and NPV. The exam mostly followed protocol, allowed for the timely and safe resumption of G-tube use, and provided the remote coverage needed for a new satellite hospital.</p><p><strong>Clinical significance: </strong>This diagnostic radiograph exam replaced the on-site fluoroscopic exam as the initial imaging exam for G-tube checking in our pediatric population.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145063673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bibliometric analysis of radiology residency theses in Türkiye: publication metrics and trends.","authors":"Ali Salbas, Ali Murat Koc","doi":"10.4274/dir.2025.253525","DOIUrl":"https://doi.org/10.4274/dir.2025.253525","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to conduct the first comprehensive bibliometric analysis of radiology residency theses in Türkiye, evaluating publication rates, indexing characteristics, citation performance, and key factors associated with successful thesis-to-publication conversion.</p><p><strong>Methods: </strong>This retrospective study included 3,136 radiology residency theses completed between 1971 and December 2024, retrieved from the National Thesis Center. Data were collected on the thesis topic, advisor title, institution type, and study design. Publication status was assessed through searches using author and advisor names and keywords across Google, Google Scholar, PubMed, Web of Science, TR Index, and DergiPark. For published articles, the journal name, indexing category, impact factor quartile, citation count, and time to publication were recorded. Statistical analyses included descriptive statistics, the chi-squared, Mann-Whitney U, and Kruskal-Wallis tests, and regression models (a <i>P</i> value of <0.05 was considered significant).</p><p><strong>Results: </strong>Most theses were from university hospitals (83.1%) and supervised by professors (45.8%). A total of 1,165 theses (37.1%) were published as journal articles, of which 651 (20.8% of all theses) appeared in Science Citation Index Expanded (SCIE)-indexed journals. Among the SCIE publications, 39.2% were in Q3 or Q4 journals. The most frequent thesis topics were neuroradiology (16.0%) and abdominal radiology (13.3%), whereas imaging physics and radiation safety was least represented (1.6%). Publication rates significantly increased over time (<i>P</i> = 0.045), and time to publication decreased (<i>P</i> < 0.001), with a median of 1,300 days. Theses supervised by assistant professors had the highest publication rate (43.0%, <i>P</i> = 0.013). University-based theses received more citations than those from training and research hospitals (<i>P</i> < 0.001). Residency students were first authors in 76.4% of publications. Articles with the advisor or another researcher as the first author were more frequently published in SCIE journals (<i>P</i> < 0.001), received more citations (<i>P</i> < 0.001), and had shorter time to publication (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Approximately one-third of radiology theses in Türkiye are published, with a notable share in SCIE-indexed journals. Thesis publication performance has improved significantly over time.</p><p><strong>Clinical significance: </strong>This study highlights the publication potential of radiology residency theses and reveals key factors associated with research visibility. Recognizing these trends may help guide institutional policies, promote academic mentorship, and encourage residents to pursue higher-impact publications. Residency theses should be regarded as integral components of scholarly activity, rather than solely as graduation requirements.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145063656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nabeel Mansour, Hannah Gildein, Frederik F Strobl, Osman Öcal, Tobias Geith, Daniel Puhr-Westerheide, Matthias Stechele, Sinan Deniz, Muzaffer R Ümütlü, Nicola Fink, Dirk Mehrens, Moritz Wildgruber, Max Seidensticker, Maximilian F Reiser, Jens Ricke, Philipp M Paprottka, Matthias P Fabritius
{"title":"Factors influencing diagnostic yield and complication risk in computed tomography fluoroscopy-guided lung biopsies: a 10-year single-center study.","authors":"Nabeel Mansour, Hannah Gildein, Frederik F Strobl, Osman Öcal, Tobias Geith, Daniel Puhr-Westerheide, Matthias Stechele, Sinan Deniz, Muzaffer R Ümütlü, Nicola Fink, Dirk Mehrens, Moritz Wildgruber, Max Seidensticker, Maximilian F Reiser, Jens Ricke, Philipp M Paprottka, Matthias P Fabritius","doi":"10.4274/dir.2025.253496","DOIUrl":"https://doi.org/10.4274/dir.2025.253496","url":null,"abstract":"<p><strong>Purpose: </strong>Computed tomography fluoroscopy (CTF)-guided biopsy is an established technique for sampling pulmonary lesions, particularly with the growing prevalence of lung nodule screening programs. This study investigated procedural and lesion-related factors affecting success and complication rates in routine CTF-guided lung core-needle biopsies at a tertiary center.</p><p><strong>Methods: </strong>Consecutive patients undergoing percutaneous CTF-guided lung biopsies over a 10-year period (2007-2016) were retrospectively analyzed. Data collected included lesion characteristics, procedural details, and outcomes, including technical and clinical success and complications. Multivariable logistic regressions were used to identify predictors of complications and biopsy failure.</p><p><strong>Results: </strong>Among 641 patients (43% female; median age 67 years) with a median lesion size of 3.1 cm, technical and clinical success rates were 99% and 93%, respectively. Clinical success was associated with multiple pulmonary lesions and longer specimen length, with multivariable analysis identifying multiple lesions as the sole independent predictor [odds ratio (OR): 2.4]. Major complications (n = 70, 11%), primarily pneumothorax (n = 62, 90%), were associated with a longer intrapulmonary needle tract, greater pleura-to-lesion distance, smaller lesion size, fissure crossing, and the presence of emphysema or subpleural air cysts. Multivariable analysis identified smaller lesion size (OR: 0.8) and greater pleura-to-lesion distance (OR: 1.5) as independent risk factors.</p><p><strong>Conclusion: </strong>CTF-guided lung biopsy is a safe and effective method for tissue sampling with high diagnostic success rates. Although multiple samples do not increase the risk of major complications, factors such as small lesion size, greater pleura-to-lesion distance, and emphysema-related changes are associated with a higher incidence of pneumothorax, emphasizing the need for risk-aware procedural planning.</p><p><strong>Clinical significance: </strong>CTF-guided lung biopsy demonstrates high diagnostic performance in routine practice. Understanding how specific anatomical features influence complication risk can guide radiologists in selecting safer biopsy approaches, especially in patients undergoing evaluation through lung cancer screening programs. Integrating these risk factors into procedural planning supports more informed, patient-centered decision-making in routine clinical practice.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Il Wan Son, Seung Baek Hong, Nam Kyung Lee, Suk Kim, Hyung Il Seo, Young Mok Park, Byeong Gwan Noh, Jong Hyun Lee
{"title":"Abbreviated liver magnetic resonance imaging with a second-shot arterial phase image to assess the viability of treated hepatocellular carcinoma after non-radiation locoregional therapy.","authors":"Il Wan Son, Seung Baek Hong, Nam Kyung Lee, Suk Kim, Hyung Il Seo, Young Mok Park, Byeong Gwan Noh, Jong Hyun Lee","doi":"10.4274/dir.2025.253482","DOIUrl":"https://doi.org/10.4274/dir.2025.253482","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the feasibility of abbreviated liver magnetic resonance imaging (AMRI) with a second-shot arterial phase (SSAP) image for the viability of treated hepatocellular carcinoma (HCC) after non-radiation locoregional therapy (LRT).</p><p><strong>Methods: </strong>We retrospectively enrolled patients with non-radiation LRT for HCC who underwent the modified gadoxetic acid-enhanced liver MRI protocol, which includes routine dynamic and SSAP imaging after the first and second injection of gadoxetic acid, respectively (6 mL and 4 mL, respectively), and an available reference standard for tumor viability in the treated HCC between March 2021 and February 2022. Two radiologists independently reviewed the full-protocol MRI (FP-MRI) and AMRI with SSAP. For the FP-MRI, observations were assigned using the Liver Imaging Reporting and Data System treatment response (LR-TR) algorithm v.2024. In the AMRI with SSAP, the observations were assigned using the abbreviated LR-TR category according to the arterial mass-like enhancement in SSAP. Ancillary features, such as diffusion restriction and T2-weighted mild-to-moderate hyperintensity, were also optionally used.</p><p><strong>Results: </strong>Of the 95 patients (70 men and 25 women; mean age, 68.7 years), 42 (44.2%) had viable lesions and 53 (55.8%) had non-viable lesions. The scan time of the simulated AMRI was significantly shorter than the FP-MRI (7.6±0.49 and 23.6±0.50 min, respectively; p<0.001). For evaluating the viability of treated HCC, there were no significant differences in the sensitivity and specificity between the FP-MRI and AMRI with SSAP (sensitivity, 85.7% vs. 80.1%, <i>P</i> = 0.500; specificity, 96.2% vs. 96.2%, <i>P</i> = 1.000).</p><p><strong>Conclusion: </strong>The abbreviated LR-TR score in AMRI with SSAP showed non-inferior diagnostic performance to FP-MRI in terms of evaluating the viability for the treated HCC, which may be helpful in clinical practice alongside a decreased scan time.</p><p><strong>Clinical significance: </strong>Abbreviated liver MRI with SSAP may be helpful for evaluating the viability of treated HCC in practice, while also providing a decreased scan time.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mecit Kantarcı, Volkan Kızılgöz, Ramazan Terzi, Ahmet Enes Kılıç, Halime Kabalcı, Önder Durmaz, Nil Tokgöz, Mustafa Harman, Ayşegül Sağır Kahraman, Ali Avanaz, Sonay Aydın, Gülsüm Özlem Elpek, Merve Yazol, Bülent Aydınlı
{"title":"Evaluating artificial intelligence for a focal nodular hyperplasia diagnosis using magnetic resonance imaging: preliminary findings.","authors":"Mecit Kantarcı, Volkan Kızılgöz, Ramazan Terzi, Ahmet Enes Kılıç, Halime Kabalcı, Önder Durmaz, Nil Tokgöz, Mustafa Harman, Ayşegül Sağır Kahraman, Ali Avanaz, Sonay Aydın, Gülsüm Özlem Elpek, Merve Yazol, Bülent Aydınlı","doi":"10.4274/dir.2025.243095","DOIUrl":"10.4274/dir.2025.243095","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the effectiveness of artificial intelligence (AI) in diagnosing focal nodular hyperplasia (FNH) of the liver using magnetic resonance imaging (MRI) and compare its performance with that of radiologists.</p><p><strong>Methods: </strong>In the first phase of the study, the MRIs of 60 patients (30 patients with FNH and 30 patients with no lesions or lesions other than FNH) were processed using a segmentation program and introduced to an AI model. After the learning process, the MRIs of 42 different patients that the AI model had no experience with were introduced to the system. In addition, a radiology resident and a radiology specialist evaluated patients with the same MR sequences. The sensitivity and specificity values were obtained from all three reviews.</p><p><strong>Results: </strong>The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the AI model were found to be 0.769, 0.966, 0.909, and 0.903, respectively. The sensitivity and specificity values were higher than those of the radiology resident and lower than those of the radiology specialist. The results of the specialist versus the AI model revealed a good agreement level, with a kappa (κ) value of 0.777.</p><p><strong>Conclusion: </strong>For the diagnosis of FNH, the sensitivity, specificity, PPV, and NPV of the AI device were higher than those of the radiology resident and lower than those of the radiology specialist. With additional studies focused on different specific lesions of the liver, AI models are expected to be able to diagnose each liver lesion with high accuracy in the future.</p><p><strong>Clinical significance: </strong>AI is studied to provide assisted or automated interpretation of radiological images with an accurate and reproducible imaging diagnosis.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":"405-415"},"PeriodicalIF":1.7,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cemal Aydın Gündoğmuş, Hande Özen Atalay, Vugar Samadli, Levent Oğuzkurt
{"title":"Factors effecting the success of retrograde tibiopedal access and recanalization in infrapopliteal artery occlusions.","authors":"Cemal Aydın Gündoğmuş, Hande Özen Atalay, Vugar Samadli, Levent Oğuzkurt","doi":"10.4274/dir.2024.242833","DOIUrl":"10.4274/dir.2024.242833","url":null,"abstract":"<p><strong>Purpose: </strong>Peripheral arterial disease (PAD) is increasingly prevalent, particularly among the aging population. Retrograde tibiopedal access (RTPA) has emerged as a useful endovascular treatment for PAD. However, there is limited research examining factors that influence the efficacy of RTPA. To investigate factors affecting the access, crossing, and recanalization success rates of RTPA for infrapopliteal PAD treatment.</p><p><strong>Methods: </strong>A retrospective study was conducted on 720 patients who underwent endovascular treatment for PAD. Of these, 104 patients (mean age: 65.5 ± 16.2; 89 men) with 131 RTPA trials were included in the final evaluation. The disease and its duration, Rutherford score, smoking status, access site, and its occlusion status, access, crossing, and recanalization success were noted. Data were analyzed using Pearson's chi-square and Mann-Whitney U tests and multivariate logistic regression to evaluate the impact of various factors on success rates.</p><p><strong>Results: </strong>The access success rate was 82.6%, the crossing success rate was 95.4%, and the recanalization success rate was 74%. Access success was significantly higher when the dorsal pedal artery (DPA) was the access artery compared with the posterior tibial artery (91.3% vs. 74.2%, <i>P</i> = 0.009). Access success was notably lower in patients with thromboangiitis obliterans compared with patients with diabetes mellitus (DM) and non-DM atherosclerosis (68.6% vs. 90.3% and 80.3%, <i>P</i> = 0.019). Recanalization success was higher when the puncture site was non-occluded (76.7% vs. 53.5%, <i>P</i> = 0.023).</p><p><strong>Conclusion: </strong>The study suggests that RTPA is a generally effective and safe technique for infrapopliteal PAD treatment. The most favorable outcomes are observed in individuals with DM who have a non-occluded DPA at the puncture site. Recanalization success is only affected by the patency of the artery at the puncture site.</p><p><strong>Clinical significance: </strong>These findings offer targeted guidance for clinicians and highlight areas requiring further investigation.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":"482-488"},"PeriodicalIF":1.7,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142153441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Celal Cinar, Erol Akgul, Alperen Elek, Mahmut Kusbeci, Egemen Ozturk, Hasan Bilen Onan, Irem Islek, Mohammad Naim Forogh, Mohammad Nawas Nasiri, Ismail Oran
{"title":"Flow-diverting stents in the management of extracranial carotid artery aneurysms.","authors":"Celal Cinar, Erol Akgul, Alperen Elek, Mahmut Kusbeci, Egemen Ozturk, Hasan Bilen Onan, Irem Islek, Mohammad Naim Forogh, Mohammad Nawas Nasiri, Ismail Oran","doi":"10.4274/dir.2024.242946","DOIUrl":"10.4274/dir.2024.242946","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to investigate the indications and therapeutic efficacy of flow-diverting stents (FDSs) in the management of extracranial carotid artery aneurysms (ECAAs) and dissections.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 18 patients treated for ECAAs with an FDS between 2010 and 2024. Patient demographics, aneurysm characteristics, procedural details, and clinical and radiologic follow-up outcomes were extracted from medical records. Procedures were performed under general anesthesia using standard endovascular techniques. Patients received preoperative and postoperative antiplatelet therapy and were fully anticoagulated during the procedure. Follow- up assessments included digital subtraction angiography or computed tomography angiography at 6-12 months and clinical evaluations to monitor symptom resolution and complications.</p><p><strong>Results: </strong>Eighteen patients, with an average age of 46.44 ± 17.54 years, underwent 19 endovascular interventions. Technical success was achieved in all cases. Single stent deployment was used in 15 aneurysms, and telescopic stent deployment in 7. Total occlusion of the aneurysm was achieved in 94.4% of cases. One patient required retreatment due to the separation of two overlapped telescopic stents. All patients were discharged within 2 days post-procedure, with symptomatic patients experiencing the complete resolution of symptoms. No complications or adverse events were reported during the follow-up period.</p><p><strong>Conclusion: </strong>The endovascular treatment of ECAAs with FDSs appears to be a safe and effective alternative, achieving high technical success and positive clinical outcomes.</p><p><strong>Clinical significance: </strong>The use of FDSs for treating ECAAs significantly improves patient outcomes with minimal complications.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":"489-495"},"PeriodicalIF":1.7,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diffusion kurtosis versus diffusion-weighted magnetic resonance imaging in differentiating clear cell renal cell carcinoma and renal angiomyolipoma with minimal fat: a comparative study.","authors":"Yarong Lin, Wenrong Zhu, Qingqiang Zhu","doi":"10.4274/dir.2025.242880","DOIUrl":"10.4274/dir.2025.242880","url":null,"abstract":"<p><strong>Purpose: </strong>To quantitatively compare the diagnostic values of conventional diffusion-weighted imaging and diffusion kurtosis imaging (DKI) in differentiating clear cell renal cell carcinoma (ccRCC) and renal angiomyolipoma with minimal fat (RAMF).</p><p><strong>Methods: </strong>Sixty-eight patients with ccRCC and 18 patients with RAMF were retrospectively studied. For DKI and apparent diffusion coefficient (ADC), respiratory-triggered echo-planar imaging sequences were acquired in the axial plane (three <i>b</i>-values: 0, 1000, 2000 s/mm<sup>2</sup>; one <i>b</i>-value: 2000 s/mm<sup>2</sup>). Mean diffusivity (MD), fractional anisotropy (FA), mean kurtosis (MK), kurtosis anisotropy (KA), radial kurtosis (RK), and ADC were evaluated. The diagnostic efficacy of various diffusion parameters in predicting ccRCC and RAMF was compared.</p><p><strong>Results: </strong>The ADC and MD values of ccRCCs were higher than those of RAMFs (<i>P</i> < 0.05), whereas comparable FA, MK, and KA values were observed between ccRCCs and RAMFs (<i>P</i> > 0.05). Moreover, the RK values of RAMFs were higher than those of ccRCCs (<i>P</i> < 0.05). Receiver operating characteristic (ROC) curve analyses showed that MD values had the highest diagnostic efficacy in differentiating ccRCCs from RAMFs. In pairwise comparisons of ROC curves and diagnostic efficacy, DKI parameters demonstrated better diagnostic accuracy than ADC in differentiating between ccRCCs and RAMFs (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>DKI analysis demonstrates superior performance than ADC analysis in differentiating ccRCC and RAMF.</p><p><strong>Clinical significance: </strong>DKI technology may serve as an additional non-invasive biomarker for the differential diagnosis of renal tumor types.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":"416-422"},"PeriodicalIF":1.7,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144674146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}