Diagnostic and interventional radiology最新文献

{"title":"Dual-energy computed tomography pulmonary angiography for pulmonary embolism: a three-tier evidence framework to guide individualized low-iodine scanning.","authors":"Qinwei Jiang, Long Qian","doi":"10.4274/dir.2026.264378","DOIUrl":"https://doi.org/10.4274/dir.2026.264378","url":null,"abstract":"<p><p>Dual-energy computed tomography (DECT) pulmonary angiography (CTPA) is widely studied for pulmonary embolism (PE) evaluation, but heterogeneity in protocols, platforms, and study designs complicates its clinical positioning. This narrative review, with structured search elements adapted from the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020, synthesized evidence from PubMed, Embase, Web of Science, and China National Knowledge Infrastructure (January 2016-June 2026); 28 studies were eligible (26 of 1,287 screened records and 2 identified through citation tracing). Evidence was organized into a three-tier framework (image quality, diagnostic performance, and clinical outcomes). Low-keV virtual monoenergetic imaging at 40-50 keV improves vascular attenuation and enables iodine load reduction to approximately 6 g in selected protocols. Pooled meta-analytic evidence shows no consistent diagnostic advantage of DECT over single-energy CT. The right ventricular/left ventricular diameter ratio remains the most stable prognostic indicator; DECT perfusion metrics have not surpassed it for mortality prediction. Iodine-map hypoperfusion in distal arteries is suspicious for, but not morphologically confirmed as, subsegmental PE; such findings carry a risk of overdiagnosis and warrant caution before anticoagulation. A body mass index- and estimated glomerular filtration rate-stratified protocol table with Oxford Centre for Evidence-Based Medicine 2011 evidence-level annotations is provided, and knowledge gaps in photon-counting CT, artificial intelligence, and cross-platform standardization are identified.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149191959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: Comparing commercial artificial intelligence for intracranial hemorrhage: Why operating points matter for procurement.","authors":"Alexander Reyes Lobo","doi":"10.4274/dir.2026.264450","DOIUrl":"10.4274/dir.2026.264450","url":null,"abstract":"","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149180016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the brachial plexus and spinal cord with diffusion tensor imaging and synthetic MRI in obstetric brachial plexus palsy: DTI of brachial plexus and spinal cord in OBPP.","authors":"Gökçen Çoban Çifçi, Hanife Avcı, Ekim Gümeler, Meltem Karataş, Akın Üzümcügil, Tüzün Fırat, Kader Karlı Oğuz, Gülgün Şengül","doi":"10.4274/dir.2026.264353","DOIUrl":"https://doi.org/10.4274/dir.2026.264353","url":null,"abstract":"<p><strong>Purpose: </strong>Obstetric brachial plexus palsy (OBPP) is conventionally staged as a peripheral nerve injury, yet conventional magnetic resonance imaging (MRI) poorly reflects microstructural neural and spinal cord changes. We evaluate whether magnetic resonance image compilation (MAGIC), a form of synthetic MRI, shows strong agreement with conventional T2-weighted short-tau inversion recovery (T2-STIR) for postganglionic injury detection, compare diffusion tensor imaging (DTI) metrics between injured and adjacent intact segments of the brachial plexus and spinal cord, and explore whether these metrics predict recovery at 2-year follow-up in infants with OBPP.</p><p><strong>Methods: </strong>In this single-center cohort with prospective enrollment and ambispective outcome assessment, 40 infants (aged 3-30 weeks) with unilateral OBPP underwent 3-T MRI during physiological sleep, comprising conventional T2-STIR, synthetic MRI (MAGIC T2-STIR), and DTI. Two blinded neuroradiologists compared synthetic and conventional sequences for postganglionic lesion detection (weighted κ). The DTI-derived fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were measured at the neural foramen (dorsal root ganglion level) and spinal cord at every injured segment and at the nearest intact segments above and below; per infant, the minimum injured value and the mean intact value were compared and related to Narakas type and 2-year recovery.</p><p><strong>Results: </strong>Synthetic MRI showed strong agreement with conventional T2-STIR (κ = 0.84-1.00); the intraobserver repeatability of DTI measurements was good to excellent [intraclass correlation coefficient (ICC) = 0.842-0.999), except for intact spinal cord ADC (ICC = 0.662). Compared with intact reference segments, injured segments showed lower FA and higher ADC at both the neural foramen (FA = 0.236 ± 0.092 vs. 0.433 ± 0.130; ADC = 2,116 ×10^-6 vs. 1,191.25 ×10^-6 mm²/s) and the spinal cord (FA = 0.321 ± 0.107 vs. 0.448 ± 0.143; ADC = 2,253.5 ×10^-6 vs. 1,191 ×10^-6 mm²/s) (all <i>P</i> < 0.001). Neither FA nor ADC differed by Narakas type or predicted 2-year recovery.</p><p><strong>Conclusion: </strong>Synthetic MRI showed strong agreement with conventional T2-STIR for the detection of postganglionic OBPP and provided six contrasts from a single acquisition of similar duration; DTI abnormalities at injured segments extended to the spinal cord, suggesting that microstructural change in OBPP may not be confined to the peripheral nerve.</p><p><strong>Clinical significance: </strong>Segmental DTI abnormality within the spinal cord raises the possibility that OBPP injury extends centrally; confirmation would require higher-resolution acquisition, technical validation against partial-volume and cerebrospinal fluid effects, and larger longitudinal cohorts before any implication for injury classification.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does superb microvascular imaging reflect hashimoto's thyroiditis or thyroid functional status?","authors":"Gökhan Kahraman","doi":"10.4274/dir.2026.264430","DOIUrl":"https://doi.org/10.4274/dir.2026.264430","url":null,"abstract":"","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply: Does superb microvascular imaging reflect Hashimoto's thyroiditis or thyroid functional status?","authors":"Tuba Selçuk Can, Sevim Özdemir, Türkan İkizceli, Behice Kaniye Yılmaz, Mehmet Akif Sarı, Rüştü Türkay, Özlem Doğan","doi":"10.4274/dir.2026.264454","DOIUrl":"https://doi.org/10.4274/dir.2026.264454","url":null,"abstract":"","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automated measurement of calcaneal inclination angle via partial semantic segmentation using U-Net.","authors":"Kendal Erincik, Umut Perçem Orhan Söylemez, Merve Gezgin, Baran Canku Karataş, Başak Atalay","doi":"10.4274/dir.2026.264385","DOIUrl":"https://doi.org/10.4274/dir.2026.264385","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;To develop and validate an interpretable deep learning pipeline for the automated measurement of the calcaneal inclination angle (CIA) on lateral weight-bearing foot radiographs using partial semantic segmentation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This retrospective single-center study included 884 radiographs after the removal of duplicates, partitioned into a development cohort of 779 radiographs and a held-out internal test cohort of 105 radiographs, with no patient contributing to both. Three landmark-relevant anatomical regions were manually annotated: the inferior calcaneal contour (CAL), inferior contour of the fifth metatarsal head (M5), and calcaneal aspect of the inferior calcaneocuboid joint (CC). Each region was segmented by its own single-class U-Net model, trained from scratch with an unweighted Dice + Binary Cross-Entropy loss and early stopping on the validation Dice score, and deterministic post-processing was used to derive four anatomical landmarks and to calculate the CIA. A second observer, a fifth-year radiology resident, independently re-annotated a random subset of 50 development radiographs from a blank canvas. The train/validation split was performed at the patient level, and each network was trained with five predefined seeds. Segmentation performance was evaluated on the validation set, and clinical measurement accuracy was assessed on the held-out test set against three readers who measured independently and blinded. The frozen primary model was then applied without modification to an independent external cohort of 50 radiographs from a second institution, measured by the same three readers under the identical blinded protocol.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Validation Dice scores across the five seeded training runs were 0.935 ± 0.010 for CAL, 0.871 ± 0.005 for M5, and 0.805 ± 0.009 for CC (mean ± standard deviation), with the pre-specified primary run reaching 0.936, 0.865, and 0.807, respectively. In the held-out test cohort, the model showed a mean absolute error (MAE) of 0.690° (95% confidence interval [CI] 0.525-0.855) against the mean of the three readers, with 92.4% of measurements within 2° and 98.1% within 3°. Bland-Altman analysis demonstrated a small negative bias of -0.425° (95% confidence interval -0.620° to -0.230°), with 95% limits of agreement from -2.427° to +1.577°. The intraclass correlation coefficient (ICC) formula ICC(A,1) achieved 0.986 across the model and the three readers and 0.994 among the three readers alone. In the external cohort, the model achieved an MAE of 0.85° against the three-reader mean, with 92.0% of measurements within 2° and an ICC of 0.969.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Partial semantic segmentation combined with deterministic landmark extraction enables rapid and clinically accurate automated CIA measurement on lateral weight-bearing foot radiographs, with an agreement approaching, though not yet equaling, that observed among human readers.","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149105522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of collimation training with radiation dose in adult chest radiography: a real‑world retrospective before‑and‑after study.","authors":"Sezer Kula, Öykü Püsküllüoğlu, İdil Sarıçam, Kayhan Çetin Atasoy","doi":"10.4274/dir.2026.264215","DOIUrl":"https://doi.org/10.4274/dir.2026.264215","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate changes in patient radiation dose following a targeted collimation training program for radiographers during routine adult chest radiography.</p><p><strong>Methods: </strong>This single-center retrospective before-and-after study included adult chest radiographs acquired on a single digital radiography system during two consecutive 3-month periods: pre-training (May-July 2025) and post-training (August-October 2025). A structured collimation training session emphasizing anatomical boundaries and the limitations of digital cropping was implemented on August 1, 2025. Dose area product (DAP) values were extracted from Digital Imaging and Communications in Medicine (DICOM) metadata. Group comparisons were performed using the Mann-Whitney U test and paired analysis using the Wilcoxon signed-rank test. Age-adjusted regression with robust standard errors was used to assess the independent association between the intervention and radiation dose.</p><p><strong>Results: </strong>A total of 3,583 adult chest radiographs (1,792 pre-training and 1,791 post-training) were analyzed. The DAP values demonstrated a markedly non-normal, positively skewed distribution in both periods. Median DAP decreased from 143.7 to 130.3 mGy·cm, representing a 9.3% reduction (<i>P</i> < 0.001). Mean DAP decreased from 173.0 ± 103.6 to 155.2 ± 98.2 mGy·cm. In the paired-patient analysis (n = 64), median DAP decreased from 139.8 to 128.9 mGy·cm, corresponding to a 7.8% reduction; however, this difference did not reach statistical significance on Wilcoxon signed-rank testing (<i>P</i> = 0.059). Following adjustment for age, examinations performed during the post-training period remained independently associated with an 11.7% lower DAP (95% confidence interval, 9.0%-14.4% lower; <i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Targeted collimation training was associated with a significant reduction in radiation dose in chest radiography. Structured training represents a simple and effective strategy for dose optimization in routine clinical practice.</p><p><strong>Clinical significance: </strong>In digital radiography, electronic cropping may mask inadequate collimation and lead to unrecognized unnecessary radiation exposure. Effective pre-exposure collimation, by limiting the irradiated field to the area of clinical interest, plays a key role in reducing patient dose and improving radiation safety in routine practice.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149105541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative assessment of active bleeding on contrast-enhanced computed tomography in primary postpartum hemorrhage.","authors":"Ryo Aoki, Kento Nakajima, Soichiro Obata, Sayuri Nakanishi, Ryosuke Shindo, Shigeru Aoki, Zenjiro Sekikawa, Daisuke Utsunomiya","doi":"10.4274/dir.2026.264384","DOIUrl":"https://doi.org/10.4274/dir.2026.264384","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate whether computed tomography (CT)-derived extravasation rate from dynamic contrast-enhanced CT is associated with invasive hemostatic intervention and clinical severity in primary postpartum hemorrhage.</p><p><strong>Methods: </strong>This retrospective single-center study included 36 patients with active intrauterine arterial bleeding on contrast-enhanced CT among 135 patients who underwent CT for primary postpartum hemorrhage between January 2020 and December 2025. The extravasation rate was calculated as the increase in extravasation volume from arterial to delayed phase divided by the interphase interval. Associations with hysterectomy and transcatheter arterial embolization (TAE), and correlations with clinical variables, were assessed.</p><p><strong>Results: </strong>The median extravasation rate was 3.7 mL/min. In the overall cohort, the extravasation rate was higher in patients who underwent hysterectomy than in those who did not, although the difference was not statistically significant (21.71 vs. 3.37 mL/min, <i>P</i> = 0.083). After exclusion of laparotomy cases, the extravasation rate tended to be higher in patients who underwent TAE than in those managed conservatively (4.07 vs. 0.90 mL/min, <i>P</i> = 0.075). Exploratory receiver operating characteristic curve analyses yielded areas under the curve of 0.705 and 0.764 for hysterectomy and TAE, respectively, although the corresponding confidence intervals were wide. The extravasation rate showed weak negative correlations with hemoglobin level (ρ = -0.356, <i>P</i> = 0.033) and hematocrit (ρ = -0.343, <i>P</i> = 0.040), whereas the correlations with systolic and diastolic blood pressure did not reach statistical significance.</p><p><strong>Conclusion: </strong>CT-derived extravasation rate showed exploratory associations with hemorrhagic severity and invasive hemostatic intervention. These preliminary findings require validation in larger studies using standardized CT acquisition and measurement protocols.</p><p><strong>Clinical significance: </strong>Quantitative assessment of contrast extravasation on dynamic CT provides a continuous imaging measure beyond the binary presence or absence of active bleeding.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149105691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computed tomography angiography of congenital left-sided obstructive heart lesions: a pictorial essay.","authors":"Zuofeng Zheng, Lei Xu","doi":"10.4274/dir.2026.264172","DOIUrl":"https://doi.org/10.4274/dir.2026.264172","url":null,"abstract":"<p><p>Congenital left-sided obstructive heart lesions (LSOLs) are a group of rare but serious congenital heart diseases. They encompass a spectrum of structural abnormalities that can obstruct blood flow at any point from the left atrium to the aortic arch. They are broadly divided into two main categories. The first is left ventricular inflow obstruction, including cor triatriatum sinister and congenital mitral stenosis. The second is left ventricular outflow obstruction, including subvalvular aortic stenosis, bicuspid aortic valve, supravalvular aortic stenosis, coarctation of the aorta, aortic arch hypoplasia, and interrupted aortic arch. When stenosis involves both left ventricular inflow and outflow obstructions, the condition is called Shone's syndrome. Computed tomography angiography (CTA) is a valuable tool for the diagnosis, treatment planning, and follow-up of LSOLs. Our goal is to review the CTA manifestations of LSOLs to better understand these congenital heart lesions.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149105555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fluoroscopy-guided colorectal stent placement for distal malignant colorectal obstruction: a retrospective single-center study.","authors":"Aycan Uysal, Mert Göl, Devrim Akıncı, Türkmen Turan Çiftçi, Emre Ünal","doi":"10.4274/dir.2026.264164","DOIUrl":"https://doi.org/10.4274/dir.2026.264164","url":null,"abstract":"<p><strong>Purpose: </strong>Malignant distal colorectal obstruction is associated with substantial morbidity and mortality when managed with emergency surgery. This study aimed to evaluate the technical and early clinical outcomes, safety, procedural radiation exposure, and stent-related reintervention of fluoroscopy-guided self-expandable metal stent (SEMS) placement.</p><p><strong>Methods: </strong>This retrospective single-center study included patients treated between January 2018 and December 2025. Bridge-to-surgery or palliative intent was established before stent placement and retrospectively abstracted from contemporaneous records. Primary end points were technical success and early clinical success within 48 hours. Secondary end points included adverse events within 30 days, stent-related reintervention, time to oral intake, total procedure time, fluoroscopy time, and dose-area product.</p><p><strong>Results: </strong>The cohort comprised 19 patients. Technical success was achieved in all patients [100%; 95% confidence interval (CI), 82.4%-100%], and early clinical success in 18 (94.7%; 95% CI, 74.0%-99.9%). Median time to oral intake was 3 days (interquartile range, 2-5 days). Median total procedure time was 38 minutes (range, 25-55 minutes). Median fluoroscopy time was 4.5 minutes (range, 3.8-8.0 minutes), and median dose-area product was 6.4 Gy·cm² (range, 5.1-8.8 Gy·cm²). One severe adverse event occurred (5.3%; 95% CI, 0.1%-26.0%): delayed perforation requiring surgery. No stent migration or 30-day mortality occurred. Stenting was performed with bridge-to-surgery intent in 5 patients and palliative intent in 14. All bridge-to-surgery patients underwent surgery after a median of 12 days; 3 underwent primary anastomosis and 2 required stoma creation. Among patients treated with palliative intent, 13 achieved early clinical success and 1 experienced clinical failure. One endoscopic reintervention for delayed stent dysfunction was performed at 150 days.</p><p><strong>Conclusion: </strong>Fluoroscopy-guided SEMS placement achieved high technical and early clinical success in selected patients with distal malignant colorectal obstruction and may provide an effective interventional radiology-led decompressive option in experienced centers.</p><p><strong>Clinical significance: </strong>Fluoroscopy-guided SEMS placement can provide timely decompression in selected patients with distal malignant colorectal obstruction within an interventional radiology-led multidisciplinary pathway, with endoscopic support available when needed.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149105658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}