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A miRNA Nanoprodrug Hydrogel for Multistage Regulation of Burn Wound Repair 用于烧伤创面修复多阶段调控的miRNA纳米前药水凝胶
IF 19 1区 材料科学
Advanced Functional Materials Pub Date : 2026-10-21 DOI: 10.1002/adfm.79180
Jiale Liang,Lan Yao,Yichen Yang,Ruiqing Wang,Xinyu Wu,Wumeng Yin,Zhiqiang Liu,Ye Chen,Botao Liu,Bin Guo,Yun Wang,Yunfeng Lin
{"title":"A miRNA Nanoprodrug Hydrogel for Multistage Regulation of Burn Wound Repair","authors":"Jiale Liang,Lan Yao,Yichen Yang,Ruiqing Wang,Xinyu Wu,Wumeng Yin,Zhiqiang Liu,Ye Chen,Botao Liu,Bin Guo,Yun Wang,Yunfeng Lin","doi":"10.1002/adfm.79180","DOIUrl":"https://doi.org/10.1002/adfm.79180","url":null,"abstract":"An RNase H-responsive tetrahedral miR-146a-5p nanoprodrug is incorporated into GelMA to form ATMP@Gel. By enhancing miRNA protection, cellular uptake, and wound-site retention, ATMP@Gel attenuates excessive inflammation and oxidative stress, promotes reparative macrophage polarization, angiogenesis, and re-epithelialization, and limits fibroblast overactivation and scar-associated remodeling, thereby coordinating multiple pathological phases of burn wound healing.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"8 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Entropy-Driven Design of an Adaptive Gel for All-Stage Inflammatory Regulation in Diabetic Peri-Implantitis 一种用于糖尿病种植体周围炎全阶段炎症调节的适应性凝胶的熵驱动设计
IF 19 1区 材料科学
Advanced Functional Materials Pub Date : 2026-10-21 DOI: 10.1002/adfm.79111
Dize Li,Kaiwen Chen,Guangyu Jian,Hongyong Zhao,Hongrui Qin,Min Jiang,Wenjun Ma,Jinhua Fan,Junyu Chen,Yuanding Huang,Huanan Wang,Tao Chen
{"title":"Entropy-Driven Design of an Adaptive Gel for All-Stage Inflammatory Regulation in Diabetic Peri-Implantitis","authors":"Dize Li,Kaiwen Chen,Guangyu Jian,Hongyong Zhao,Hongrui Qin,Min Jiang,Wenjun Ma,Jinhua Fan,Junyu Chen,Yuanding Huang,Huanan Wang,Tao Chen","doi":"10.1002/adfm.79111","DOIUrl":"https://doi.org/10.1002/adfm.79111","url":null,"abstract":"Diabetic peri-implantitis involves failed inflammation resolution. We developed CGCI, an injectable composite gel delivering early antibacterial Cu2+ and sustained IL-10 to promote efferocytosis and vascular/lymphatic remodeling. A structural-entropy model guides stage-specific release. Single-cell transcriptomics reveals macrophage-endothelial crosstalk. In beagle models, CGCI achieves all-stage regulation and tissue regeneration.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"62 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Programmed Curing Directs Nanophase Organization in Active Ester-Cured Epoxies for Strong Adhesion, Toughness, and Recyclability 程序固化指导纳米相组织的活性酯固化环氧树脂强附着力，韧性和可回收性
IF 19 1区 材料科学
Advanced Functional Materials Pub Date : 2026-10-19 DOI: 10.1002/adfm.79115
Chenyang Xu,Jingkai Liu,Shuaipeng Wang,Kerong Yang,Ziyu Liu,Xin Wang,Jinyue Dai,Xiaoqing Liu
{"title":"Programmed Curing Directs Nanophase Organization in Active Ester-Cured Epoxies for Strong Adhesion, Toughness, and Recyclability","authors":"Chenyang Xu,Jingkai Liu,Shuaipeng Wang,Kerong Yang,Ziyu Liu,Xin Wang,Jinyue Dai,Xiaoqing Liu","doi":"10.1002/adfm.79115","DOIUrl":"https://doi.org/10.1002/adfm.79115","url":null,"abstract":"Sequentially reactive active ester hardeners create a pre-gelation structural-evolution window in low-hydroxyl epoxy networks. Through coordinated dodecyl/furfuryl curing, C12 segments form confined alkyl-rich nanodomains, while ester-containing species accumulate at metal interfaces, combining low dielectric response, strong adhesion, hydrothermal stability, and acid-triggered recovery of feedstocks and encapsulated components for sustainable electronic packaging.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"73 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cation-Directed Solvent Inclusion in Zero-Dimensional Indium Halides for Tunable and Stimuli-Responsive Emission 零维卤化铟中阳离子导向溶剂包合的可调谐和刺激响应发射
IF 19 1区 材料科学
Advanced Functional Materials Pub Date : 2026-10-19 DOI: 10.1002/adfm.79054
Wenhui Qin,Xin Mao,Jinhua Rao,Hong Yin,Wenzhi Li,Dong Zhai,Junsheng Chen,Ruiling Zhang
{"title":"Cation-Directed Solvent Inclusion in Zero-Dimensional Indium Halides for Tunable and Stimuli-Responsive Emission","authors":"Wenhui Qin,Xin Mao,Jinhua Rao,Hong Yin,Wenzhi Li,Dong Zhai,Junsheng Chen,Ruiling Zhang","doi":"10.1002/adfm.79054","DOIUrl":"https://doi.org/10.1002/adfm.79054","url":null,"abstract":"A series of antimony-doped zero-dimensional indium chlorides with guest solvent molecules are reported. These host-guest systems exhibit solvent-dependent photoluminescence properties. Specifically, 1·2H2O·MeOH:Sb displays a single-band yellow emission, whereas the other systems exhibit tunable dual-band emission. Moreover, reversible switching between yellow and orange-red emission can be achieved under external stimuli due to the structural phase transitions between 1·2H2O·MeOH:Sb and 1·H2O:Sb.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"33 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synergizing Proton Transfer and Oxygen Activation via Brønsted/Lewis Acid-Site Regulation in K-Doped La0.5Sr0.5-xKxMn0.9Co0.1O3-δ Air Electrode for Reversible Protonic Ceramic Electrochemical Cells 可逆质子陶瓷电化学电池中掺杂k的La0.5Sr0.5-xKxMn0.9Co0.1O3-δ空气电极通过Brønsted/Lewis酸位调控协同质子转移和氧活化
IF 19 1区 材料科学
Advanced Functional Materials Pub Date : 2026-10-19 DOI: 10.1002/adfm.79043
Xiaomei Huang,Min Fu,Shuang Wang,Yibin Wang,Zheng Qian,Yanbing Gong,Zhifei Hao,Tianjia Chen,Daqian Ding,Yongfeng Zhang,Zetian Tao
{"title":"Synergizing Proton Transfer and Oxygen Activation via Brønsted/Lewis Acid-Site Regulation in K-Doped La0.5Sr0.5-xKxMn0.9Co0.1O3-δ Air Electrode for Reversible Protonic Ceramic Electrochemical Cells","authors":"Xiaomei Huang,Min Fu,Shuang Wang,Yibin Wang,Zheng Qian,Yanbing Gong,Zhifei Hao,Tianjia Chen,Daqian Ding,Yongfeng Zhang,Zetian Tao","doi":"10.1002/adfm.79043","DOIUrl":"https://doi.org/10.1002/adfm.79043","url":null,"abstract":"K substitution within a fixed Co incorporated La0.5Sr0.5MnO3-δ framework tailors surface acid chemistry, establishing a favorable balance of Brønsted and Lewis acid sites in K10. This balance facilitates proton transfer, H2O dissociation, and O2 activation, promoting proton coupled electron transfer and oxygen electrode kinetics in reversible protonic ceramic electrochemical cells.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"43 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interfacial Inner-Local-Enhanced Discharge Induced by Aligned Needle Electrodes for the Synergistic Collection of Tribo-Charges 定向针状电极诱导的摩擦电荷协同收集界面局部增强放电
IF 19 1区 材料科学
Advanced Functional Materials Pub Date : 2026-10-19 DOI: 10.1002/adfm.79101
Cuiling Zhang,Kaixian Li,Chuncai Shan,Siqi Gong,Shuyan Xu,Huiyuan Wu,Xue Wang,Chenguo Hu
{"title":"Interfacial Inner-Local-Enhanced Discharge Induced by Aligned Needle Electrodes for the Synergistic Collection of Tribo-Charges","authors":"Cuiling Zhang,Kaixian Li,Chuncai Shan,Siqi Gong,Shuyan Xu,Huiyuan Wu,Xue Wang,Chenguo Hu","doi":"10.1002/adfm.79101","DOIUrl":"https://doi.org/10.1002/adfm.79101","url":null,"abstract":"A four-region alternating charge distribution model was reported and achieved synergistic interfacial tribo-charge collection by combining inner-aligned needle electrodes with side electrodes, thereby enhancing the efficiency of electrostatic energy extraction by 4-fold.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"4 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Giant Atomic Displacement Driven Reconstructive Molecular Martensitic Structural Phase Transition in 1D Hybrid Metal Halide Actuator 一维杂化金属卤化物驱动器中巨原子位移驱动重建分子马氏体结构相变
IF 19 1区 材料科学
Advanced Functional Materials Pub Date : 2026-10-19 DOI: 10.1002/adfm.79152
Chao-Yang Chai,Qiang-Qiang Bi,Cheng-Dong Liu,Zhao-Rui Hua,Shu-Yin Jia,Jia-Hang Wu,Fei-Yang Li,Shuo Tan,Zhong-Xia Wang,Wen Zhang
{"title":"Giant Atomic Displacement Driven Reconstructive Molecular Martensitic Structural Phase Transition in 1D Hybrid Metal Halide Actuator","authors":"Chao-Yang Chai,Qiang-Qiang Bi,Cheng-Dong Liu,Zhao-Rui Hua,Shu-Yin Jia,Jia-Hang Wu,Fei-Yang Li,Shuo Tan,Zhong-Xia Wang,Wen Zhang","doi":"10.1002/adfm.79152","DOIUrl":"https://doi.org/10.1002/adfm.79152","url":null,"abstract":"The structural reconstruction of local inorganic octahedra changing from face-sharing to edge-sharing linkages is driven by giant atomic displacements. This process triggers the molecular martensitic transformation behavior by shearing and cooperative deflection of inorganic chains.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"73 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydrophobic Microenvironment Engineering of Single-Atom Nanozymes for Proteolysis-Driven Marine Antifouling 单原子纳米酶蛋白水解驱动的海洋防污疏水微环境工程
IF 19 1区 材料科学
Advanced Functional Materials Pub Date : 2026-10-19 DOI: 10.1002/adfm.79140
Wenhua Zheng,Sheng Zhao,Fanxiang Meng,Yudi Zhao,Shixia Bian,Zezheng Ye,Hongyu Lin,Wengang Liu,Ning Sui,Jun Deng,Zhiling Zhu
{"title":"Hydrophobic Microenvironment Engineering of Single-Atom Nanozymes for Proteolysis-Driven Marine Antifouling","authors":"Wenhua Zheng,Sheng Zhao,Fanxiang Meng,Yudi Zhao,Shixia Bian,Zezheng Ye,Hongyu Lin,Wengang Liu,Ning Sui,Jun Deng,Zhiling Zhu","doi":"10.1002/adfm.79140","DOIUrl":"https://doi.org/10.1002/adfm.79140","url":null,"abstract":"The Cu-NC HSA transposes the hydrophobic microenvironment of natural proteases while introducing a spin-polarized d9–d10 Cu active center distinct from the closed-shell Zn site. By integrating biomimetic substrate confinement with an electronically reprogrammed Cu center, this design enables proteolytic catalysis. Active-site structure and spin state of the native protease thermolysin (left). Structure, spin state, and limitations of conventional Cu-based catalysts (upper right). Structure, spin state, and advantages of the biomimetic Cu-NC HSA nanozyme developed in this work (lower right).","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"16 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Switching Superconductivity with Uniaxial Strain in a high- Cuprate Superconductor 高铜超导体中单轴应变的开关超导性
IF 19 1区 材料科学
Advanced Functional Materials Pub Date : 2026-10-19 DOI: 10.1002/adfm.79027
Baizhi Gao,Qianli Ma,Bruce D. Gaulin,Young-June Kim
{"title":"Switching Superconductivity with Uniaxial Strain in a high- Cuprate Superconductor","authors":"Baizhi Gao,Qianli Ma,Bruce D. Gaulin,Young-June Kim","doi":"10.1002/adfm.79027","DOIUrl":"https://doi.org/10.1002/adfm.79027","url":null,"abstract":"Uniaxial strain is demonstrated as a new scheme for a superconductivity switch. Exploiting the large strain-induced Tc shift in a cuprate superconductor enables robust switching between superconducting and normal states over 100 cycles with only 0.1% strain. This approach has been shown to be non-volatile and locally addressable, highlighting its potential for application.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"36 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Highly Permeable Polyamide Membranes Based on Hexafluoroisopropylidene Molecular Scaffold for Efficient Organic Solvent Nanofiltration 基于六氟异丙烯分子支架的高渗透聚酰胺膜高效纳滤有机溶剂
IF 19 1区 材料科学
Advanced Functional Materials Pub Date : 2026-10-19 DOI: 10.1002/adfm.79167
Yun Shen,Shideng Yuan,Fuping Han,Peijun Zheng,Xiang Ma,Xin Liu,Manshu Zhao,Yiming Li,Yue Chen,Zhining Wang
{"title":"Highly Permeable Polyamide Membranes Based on Hexafluoroisopropylidene Molecular Scaffold for Efficient Organic Solvent Nanofiltration","authors":"Yun Shen,Shideng Yuan,Fuping Han,Peijun Zheng,Xiang Ma,Xin Liu,Manshu Zhao,Yiming Li,Yue Chen,Zhining Wang","doi":"10.1002/adfm.79167","DOIUrl":"https://doi.org/10.1002/adfm.79167","url":null,"abstract":"A highly permeable OSN membrane with great stability was designed based on a molecular scaffold. The packing behavior of polyamide chains and the solvent-membrane interactions was effectively regulated, and the prepared TFC membrane exhibited an excellent methanol permeance of 20.3 L m−2 h−1 bar−1 and achieved an efficient sieving of photosensitizer/precursor mixture system.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"1 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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