Dental and Medical Problems最新文献

{"title":"Effects of injectable platelet-rich fibrin and Hank's balanced salt solution as rejuvenating media for the periodontal ligament cells of avulsed teeth.","authors":"İrem Bağ Baytar, Berceste Güler Ayyıldız, Sibel Yıldırım","doi":"10.17219/dmp/187833","DOIUrl":"https://doi.org/10.17219/dmp/187833","url":null,"abstract":"<p><strong>Background: </strong>The problem of avulsed teeth often being brought to the clinic in a dry state remains unresolved in the literature. Before an avulsed tooth is replanted, the periodontal ligament (PDL) cells require an appropriate storage medium to preserve their viability and biological properties. Hank's balanced salt solution (HBSS) is the reference medium recommended for this purpose in the literature.</p><p><strong>Objectives: </strong>The aim of the present study was to compare the effects of the reference solution - HBSS - and injectable platelet-rich fibrin (I-PRF) on the differentiation of PDL fibroblasts by examining the differentiation markers associated with osteoblastic, osteoclastic, fibroblastic, and cementoblastic lineages.</p><p><strong>Material and methods: </strong>Twenty freshly extracted third molar teeth were used for cell isolation. After being left to dry for 30 min, the teeth were immersed for 30 min at room temperature in HBSS (n = 7) or I-PRF (n = 7). For the positive control group (n = 3), cells were isolated immediately after extraction, whereas for the negative control group (n = 3), cells were isolated after 30 min of dry time. Viable cells were counted, and immunofluorescence staining was performed to assess cell differentiation, using antibodies against Runt-related transcription factor 2 (RUNX2), receptor activator of nuclear factor kappa-B ligand (RANKL), collagen type I (COL1), and cementum attachment protein (CAP). Integrated density (IntDen) was measured using the ImageJ software.</p><p><strong>Results: </strong>There were no statistically significant differences between the HBSS and I-PRF groups in the expression of RUNX2, RANKL or CAP. The I-PRF group showed significantly higher expression of COL1 (p < 0.01).</p><p><strong>Conclusions: </strong>Injectable PRF may contribute to the regeneration of PDL cells when used as a rejuvenating medium before replantation following an extraoral dry period.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"63 4","pages":"917-924"},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148808255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-year follow-up of the additive effect of concentrated growth factor to the coronally advanced flap in Miller's class I and class II recession defects: A randomized controlled clinical trial.","authors":"Vazeeha Afrin Syed, Chanchal Katariya, Arvina Rajasekar, Sankari Malaiappan, Jaiganesh Ramamurthy","doi":"10.17219/dmp/190426","DOIUrl":"10.17219/dmp/190426","url":null,"abstract":"<p><strong>Background: </strong>The fundamental goals of traditional periodontal therapy have been the eradication of disease and the preservation of a healthy, functional dentition and its supporting tissues. However, in recent years, the emphasis has shifted increasingly toward esthetic outcomes, extending beyond dental prostheses and tooth color to encompass the soft tissues surrounding the dentition.</p><p><strong>Objectives: </strong>The main aim of this research was to compare the impact of the coronally advanced flap (CAF) in combination with concentrated growth factor (CGF) with that of CAF alone in the management of gingival recession.</p><p><strong>Material and methods: </strong>This randomized controlled trial (RCT) included 90 patients with Miller's class I or class II gingival recession, who were categorized into 2 groups: CAF; and CAF with CGF. Follow-up assessments were conducted at 6 months, 1 year and 3 years. Periodontal clinical parameters, along with buccal recession depth (BRD) and the width of attached gingiva (AGW), were measured. Postoperative pain was assessed using a visual analog scale (VAS) 10 days after the intervention in both groups. Statistical analysis was performed using IBM SPSS Statistics for Windows, v. 23.</p><p><strong>Results: </strong>The CAF+CGF group showed better results in terms of mean BRD, AGW and clinical attachment level (CAL), as well as reduced postoperative pain (p < 0.05).</p><p><strong>Conclusions: </strong>With a 3-year long-term follow-up, the present trial supports the additive effect of CGF in combination with CAF for maxillary gingival augmentation coronal to the recession.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"63 4","pages":"869-874"},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148758942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peri-implant soft tissue thickness following connective tissue grafting or volume-stable collagen matrix augmentation: A randomized controlled trial.","authors":"Jakub Hadzik, Marzena Dominiak","doi":"10.17219/dmp/222370","DOIUrl":"10.17219/dmp/222370","url":null,"abstract":"<p><strong>Background: </strong>Peri-implant soft tissue thickness (STT) is considered as an important factor influencing marginal bone stability and esthetic outcomes; however, the effectiveness of different augmentation materials and the impact of augmentation timing remain unclear.</p><p><strong>Objectives: </strong>The aim of this study was to compare changes in peri-implant SST following augmentation with a subepithelial connective tissue graft (CTG) or a volume-stable collagen matrix (VCMX) vs. non-augmented control sites, and to explore the potential influence of augmentation timing.</p><p><strong>Material and methods: </strong>In this randomized controlled clinical trial (RCT), 36 patients with 40 implant sites in the esthetic zone were allocated to the CTG (n = 16), VCMX (n = 16) or non-augmented control (n = 8) groups. Within the CTG and VCMX groups, implant sites were further subdivided according to augmentation timing (staged vs. simultaneous), with each subgroup consisting of 8 implant sites. Soft tissue augmentation was performed either prior to implant placement or simultaneously with implant insertion. Soft tissue thickness was assessed using standardized ultrasonographic measurements at baseline (T0), 3 months (T1) and 12 months (T2). Marginal bone loss (MBL) and complications were recorded as secondary outcomes.</p><p><strong>Results: </strong>Both augmentation methods resulted in significantly greater SST as compared to non-augmented sites (p < 0.001). At T2, CTGs tended to achieve greater final thickness than the collagen matrix (a difference of 0.3-0.6 mm in the final SST). All augmented sites exceeded 2 mm mucosal thickness. No statistically significant differences related to augmentation timing were detected. Marginal bone loss was low and comparable among the groups, and no biological or technical complications were observed.</p><p><strong>Conclusions: </strong>Soft tissue augmentation results in clinically relevant and stable increases in peri-implant tissue thickness. Connective tissue grafts tended to provide greater final thickness, whereas the collagen matrix may represent a reliable and less invasive alternative. No statistically significant influence of augmentation timing on the final STT outcomes was detected over 12 months.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148344169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrasinus versus extrasinus zygomatic implant placement: A 5-year retrospective observational analysis of survival and complications.","authors":"Paweł Aleksandrowicz, Jolanta Sikorska, Justyna Klempka, Adam Stepniewski, Michał Oszwałdowski, Lidia Zofia Kotuła, Andrzej Wojtowicz","doi":"10.17219/dmp/220978","DOIUrl":"10.17219/dmp/220978","url":null,"abstract":"<p><strong>Background: </strong>Edentulism, a common condition, may be congenital or acquired later in life as a result of dental caries, periodontitis, aging, craniofacial trauma, or tumor resection. The rehabilitation of missing teeth can be achieved with dental implants. In cases of insufficient alveolar bone, several treatment options have been described in the literature, including maxillary sinus augmentation with bone grafting, the Le Fort I osteotomy, the angulated placement of conventional implants, and the use of specialized implants, such as zygomatic implants, which are anchored in the zygomatic bone.</p><p><strong>Objectives: </strong>The aim of this retrospective study was to compare 2 surgical approaches - intrasinus and extrasinus - for the placement of zygomatic implants in patients with severe maxillary atrophy.</p><p><strong>Material and methods: </strong>The study was based on the medical records of patients who underwent zygomatic implant treatment conducted by the same surgeon at 2 dental facilities in Poland between 2004 and 2021. A total of 190 zygomatic implants placed in 69 patients of varying age and sex were included in the analysis. The follow-up period was 5 years. Two surgical approaches for zygomatic implant placement - intrasinus and extrasinus - were evaluated. Statistical analysis was performed using a significance level of 0.05. Differences between the groups were assessed using the χ2 test or Fisher's exact test, as appropriate.</p><p><strong>Results: </strong>The zygomatic implants placed using the intrasinus approach demonstrated a 100% survival rate. In the extrasinus group, the osseointegration rate was 94.27%, with implant loss occurring in 7 patients. Maxillary sinusitis was observed in 7 patients. Soft-tissue atrophy occurred in 4 patients (8.33%) and involved 14 zygomatic implants placed using the extrasinus technique. Cutaneous fistulas developed in 2 patients treated with the extrasinus approach. One case of zygomatic bone fracture was reported in the extrasinus group.</p><p><strong>Conclusions: </strong>No statistically significant differences in the complication rates were observed between the intrasinus and extrasinus techniques for zygomatic implant placement. Both approaches appear to be equally effective for the rehabilitation of patients with severe maxillary atrophy.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148344126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HAp-ZrO2-AgNP-reinforced polystyrene dental nanocomposites: Antibacterial, antiplaque and self-cleaning properties.","authors":"Hadi Zare-Zardini, Elham Saberian, Andrej Jenča, Adriána Petrášová, Janka Jenčová, Andrej Jenča, Eliška Kubíková, Tetyana Pyndus, Mieszko Adam Więckiewicz","doi":"10.17219/dmp/213852","DOIUrl":"https://doi.org/10.17219/dmp/213852","url":null,"abstract":"<p><strong>Background: </strong>Dental biofilms, primarily driven by Streptococcus mutans, are the main etiological agents of caries and restorative failure.</p><p><strong>Objectives: </strong>The aim of the study was to design and synthesize a novel polystyrene (PS)-based nanocomposite reinforced with hydroxyapatite (HAp), zirconia (ZrO2) and silver nanoparticles (AgNPs).</p><p><strong>Material and methods: </strong>Hydroxyapatite, ZrO2 and AgNPs were synthesized via wet precipitation, sol-gel and citrate reduction methods, respectively. The nanoparticles (5 wt% total loading) were uniformly dispersed in a toluene-based PS matrix using ultrasonic-assisted solution casting. The resulting films were characterized in terms of morphology (scanning electron microscopy (SEM), transmission electron microscopy (TEM), atomic force microscopy (AFM)), composition (energy-dispersive X-ray spectroscopy (EDX)), thermal stability (thermogravimetric analysis (TGA)), mechanical properties (tensile strength, Young's modulus, Vickers hardness), surface wettability (water contact angle (WCA)), antibacterial efficacy (zone of inhibition (ZOI), minimum inhibitory concentration/minimum bactericidal concentration (MIC/MBC), colony-forming unit (CFU) assay), and antibiofilm activity (crystal violet staining, confocal laser scanning microscopy (CLSM)). Statistical analysis was performed using one-way analysis of variance (ANOVA) and Tukey's honestly significant difference (HSD) test (p < 0.05).</p><p><strong>Results: </strong>The nanocomposite exhibited a 30% increase in tensile strength (32.5 MPa vs. 25 MPa for pure PS) and a 25% rise in elastic modulus (1.5 GPa vs. 1.2 GPa). The water contact angle increased from 85° ±2° (pure PS) to 115° ±3° (nanocomposite), confirming significantly enhanced hydrophobicity. The composite demonstrated strong antibacterial activity, with a ZOI of 15.3 mm, MIC of 6.25 mg/mL, MBC of 12.5 mg/mL, and 99.8% bacterial reduction within 24 h. Antibiofilm performance was also notable, showing a 91.2% reduction in biofilm biomass after 72 h and 74.8% decrease in biofilm thickness (from 32.5 μm to 8.2 μm). Confocal laser scanning microscopy revealed a marked shift in the live/dead cell ratio (from 4.7:1 to 0.6:1), confirming bactericidal rather than bacteriostatic action. All nanoparticles were homogeneously distributed without agglomeration, as confirmed by SEM/EDX and TEM.</p><p><strong>Conclusions: </strong>The HAp-ZrO2-AgNP-reinforced PS nanocomposite integrates enhanced mechanical properties, self-cleaning surface characteristics, and potent, long-lasting antibiofilm activity against S. mutans. While further biocompatibility and clinical translation studies are warranted, this material represents a significant leap toward durable, infection-resistant dental applications.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148263683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral microbiota diversity and composition in patients with oral lichen planus: An observational molecular analysis study.","authors":"Elham Saberian, Adriána Petrášová, Andrej Jenča, Janka Jenčová, Kimia Shirali, Andrej Jenča, Mieszko Adam Więckiewicz, Hadi Zare-Zardini, Meysam Ebrahimi Far","doi":"10.17219/dmp/210087","DOIUrl":"https://doi.org/10.17219/dmp/210087","url":null,"abstract":"<p><strong>Background: </strong>Oral lichen planus (OLP) is a chronic inflammatory condition affecting the oral mucosa. The oral microbiome has been identified as a potential contributing factor to OLP.</p><p><strong>Objectives: </strong>The aim of the study was to evaluate the prevalence and diversity of the oral microbiota in patients with OLP.</p><p><strong>Material and methods: </strong>This observational study included 78 patients with clinically and histopathologically confirmed OLP, recruited in accordance with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines. Buccal mucosa samples were collected using standardized protocols. DNA was extracted from 12 high-quality samples and subjected to 16S rRNA gene amplification and sequencing. Alpha and beta diversity indices were calculated using the Quantitative Insights Into Microbial Ecology (QIIME) platform. Statistical analyses were performed using the IBM SPSS Statistics for Windows software, v. 26.0 (IBM Corp., Armonk, USA) (p < 0.05).</p><p><strong>Results: </strong>Intratissue bacterial communities exhibited decreased alpha diversity and increased beta diversity compared with those present on the mucosal surface. Streptococcus, a genus within the Firmicutes phylum, was found to be the most abundant, with 5 Streptococcus strains identified in the OLP samples. Following Streptococci, Bacilli and Clostridia displayed considerable diversity. Other frequently detected species included Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Eikenella corrodens, Actinobacillus, as well as members of the Proteobacteria phylum, which are commonly found in high quantities in the oral cavity. Prevotella and Capnocytophaga, belonging to the Bacteroidetes phylum, were also frequently observed. Alpha diversity analysis revealed significant differences in the colony numbers of the investigated species across studied samples.</p><p><strong>Conclusions: </strong>The findings indicate an association between the composition of the oral microbiota and OLP. The microbial populations obtained from affected individuals exhibited distinct bacterial compositions. Modulation of the oral microbiome may represent a potential strategy for improving the management of OLP.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148028201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laser therapies as the adjunctive treatment of medication-related osteonecrosis of the jaw: Evidence synthesis and clinical recommendations. Official recommendations of the World Federation for Laser Dentistry (WFLD) and the Polish Society for Laser Dentistry (PTSL).","authors":"Kinga Grzech-Leśniak, Rafał Wiench, Jamil Awad Shibli, Jakub Fiegler-Rudol, Ilaria Giovannacci, Jacek Matys, Zuzanna Grzech-Leśniak, Adam Ziemlewski, Marek Ussowicz, Marzena Dominiak, Krzysztof Dowgierd, Tomasz Wróbel, Marco Meleti, Aldo Brugnera Júnior, Maha Ramzy Taalab, Mariusz Szuta, Josep Arnabat Dominguez, Alessandro Del Vecchio, Octavi Camps-Font, Praveen Arany, Georgios E Romanos, Umberto Romeo, Akira Aoki, Samir Nammour, Paolo Vescovi","doi":"10.17219/dmp/220709","DOIUrl":"https://doi.org/10.17219/dmp/220709","url":null,"abstract":"<p><p>Medication-related osteonecrosis of the jaw (MRONJ) is a severe complication associated with antiresorptive and antiangiogenic therapies. Laser-based approaches, including photobiomodulation therapy (PBMT) and erbium laser-assisted surgery, have been proposed as adjunctive interventions to improve healing and clinical outcomes. This consensus-based review aimed to synthesize evidence from systematic reviews and meta-analyses evaluating laser-based therapies in the prevention and treatment of MRONJ, and to translate these findings into clinical recommendations developed by the World Federation for Laser Dentistry (WFLD) and the Polish Society for Laser Dentistry (PTSL).The review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 and Joanna Briggs Institute (JBI) guidance, and was prospectively registered in the International Prospective Register of Systematic Reviews (PROSPERO). An electronic search of the PubMed/MEDLINE, Embase, Scopus, and Cochrane Library databases was conducted for systematic reviews and meta-analyses published between January 2015 and October 2025. Study selection, data extraction and methodological assessment were performed independently by 3 reviewers.Eighty-five records were identified, and 14 reviews met the inclusion criteria. These included several hundred primary studies, mainly observational studies and case series. Laser-based interventions were primarily used as adjuncts to conventional MRONJ management. Photobiomodulation therapy was associated with pain reduction and improved soft tissue healing, while erbium-doped yttrium aluminum garnet (Er:YAG) laser-assisted surgery enabled the precise removal of necrotic bone. Combined protocols showed generally favorable trends. However, substantial heterogeneity in study design, laser parameters and outcome definitions precluded quantitative synthesis.Laser-based therapies may provide beneficial adjunctive effects in MRONJ management, particularly within multimodal treatment strategies. However, the strength of these conclusions is limited due to substantial heterogeneity in study design, laser protocols and outcome reporting.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147971492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of heartfulness meditation in the management of recurrent aphthous ulcers.","authors":"Madhulika Yadav, Neha Rathore, Ashish Katiyar, Ravish Ahuja, Amogh Tanwar, Sahana Shivkumar, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini","doi":"10.17219/dmp/168912","DOIUrl":"10.17219/dmp/168912","url":null,"abstract":"<p><strong>Background: </strong>Recurrent aphthous ulcers (RAUs) are the most prevalent form of painful oral mucosal disorder. Conventional treatment for RAUs involves the administration of tetracycline, which has been shown to alleviate clinical signs and symptoms. However, this medication has been associated with a number of adverse effects. Heartfulness meditation (HM) has been shown to facilitate natural healing of ulcers without complications by developing a compassionate connection with oneself.</p><p><strong>Objectives: </strong>The aim of the study was to evaluate the effectiveness of HM in the management of RAUs and to compare its effects with those of conventional treatment.</p><p><strong>Material and methods: </strong>A parallel study was conducted among 54 patients affected with RAUs. The patients were divided into 3 groups: group 1 - HM; group 2 - tetracycline treatment; and group 3 - combination of tetracycline treatment and HM. The evaluated outcomes included pain levels and the duration of ulceration. One-way analysis of variance (ANOVA) and paired t-test were applied to identify significant differences between the groups.</p><p><strong>Results: </strong>A substantial decrease in pain intensity was observed during HM. The group that engaged in meditation alongside tetracycline treatment exhibited the lowest pain scores. At follow-up intervals of 3, 5 and 7 days, pain levels between the tetracycline group and the HM group were similar. The group that received a combination of tetracycline treatment and HM demonstrated the shortest duration of ulcers (7.167 ±0.383 days).</p><p><strong>Conclusions: </strong>The study concluded that when HM was practiced in addition to tetracycline treatment, it demonstrated superior efficacy in reducing pain at the shortest time. Furthermore, the study noted a reduction in the duration of ulcers when HM was used in conjunction with tetracycline, as compared to the practice of HM alone.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":" ","pages":"591-596"},"PeriodicalIF":4.3,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of orofacial function and sleep disorders in children with signs of autism spectrum disorder: A cross-sectional study.","authors":"Masatoshi Otsugu, Maika Kadono, Yusuke Mikasa, Ikuko Mohri, Kuriko Kagitani-Shimono, Masaya Tachibana, Masako Taniike, Kazuhiko Nakano, Takafumi Kato","doi":"10.17219/dmp/211355","DOIUrl":"10.17219/dmp/211355","url":null,"abstract":"<p><strong>Background: </strong>Children with autism spectrum disorder (ASD) have higher rates of feeding problems and sleep disorders. Research on feeding problems in children with ASD has focused on behavioral, psychological and nutritional aspects. However, the biomechanics underlying these issues remains unknown.</p><p><strong>Objectives: </strong>The present study aimed to evaluate the relationship between signs of ASD, orofacial function and sleep disorders in children.</p><p><strong>Material and methods: </strong>A total of 56 Japanese early elementary school children aged 6-9 years were recruited. The subjects underwent physical examinations, intraoral inspections and orofacial functional assessments. The parents or legal guardians of the children completed questionnaires regarding the subjects' dietary and meal habits, the Social Responsiveness Scale, Second Edition (SRS-2), and the Japanese Sleep Questionnaire for Elementary Schoolers (JSQ-ES). Each assessment item was compared between 2 groups divided according to the SRS-2 scores, and the relationships with psychological traits were investigated using Spearman's rank correlation coefficient.</p><p><strong>Results: </strong>Thirteen of the 56 children had SRS-2 T scores ≥60, indicating possible ASD. Masticatory performance was significantly lower in the high SRS-2 group than in the low SRS-2 group (p < 0.05). Additionally, the high SRS-2 group showed significantly higher T scores on the JSQ-ES for insomnia (p < 0.05) and excessive daytime sleepiness (p < 0.01). Occlusal force (p < 0.05), masticatory performance (p < 0.05), insomnia (p < 0.001), and excessive daytime sleepiness (p < 0.001) were significantly correlated with the SRS-2 score.</p><p><strong>Conclusions: </strong>These results suggest that low masticatory performance contributes to feeding problems in children with signs of ASD. Additionally, the severity of ASD symptoms is associated with the severity of orofacial functional and feeding problems, as well as sleep disorders.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":" ","pages":"579-589"},"PeriodicalIF":4.3,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148028222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between malocclusion severity and adolescents' psychosocial status.","authors":"Berfin Karbeyazgün Çınar, Rosaria Bucci, Simona Cascella, Vincenzo D'antò, Vittorio Simeon, Roberto Rongo, Rosa Valletta","doi":"10.17219/dmp/204826","DOIUrl":"10.17219/dmp/204826","url":null,"abstract":"<p><strong>Background: </strong>The impact of dentoskeletal malocclusion on the psychosocial status and oral health-related quality of life (OHRQoL), especially in adolescents, has been a subject of considerable debate in the literature.</p><p><strong>Objectives: </strong>The aim of the study was to explore the relationship between the severity of dental and skeletal malocclusions and adolescents' self-esteem, their perception of dentofacial aesthetics, and the psychosocial impact of dental aesthetics.</p><p><strong>Material and methods: </strong>Adolescent patients (aged 10-18 years) seeking orthodontic treatment in a hospital clinic were recruited for the study. The Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ), the Orofacial Esthetic Scale (OES), the Rosenberg Self-Esteem Scale (RSES), and the Aesthetic Component of the index of orthodontic treatment need (IOTN-AC) were administered during the first consultation. Overbite (OVB), overjet (OVJ) and the Dental Health Component of the IOTN (IOTN-DHC) were measured by a trained operator on digital models. Lateral cephalometric radiographs were used to evaluate skeletal malocclusions in the sagittal and vertical planes. Comparisons between the groups were performed using analysis of variance (ANOVA), the Kruskal-Wallis test or the χ2 test. Correlations between variables were assessed using Pearson's or Spearman's correlation tests.</p><p><strong>Results: </strong>The majority of adolescents classified according to the IOTN-DSC as having a definite need for orthodontic treatment by clinicians perceived their own need for treatment as low or non-existent. No statistically significant differences were found in the PIDAQ, OES and RSES scores among different IOTN-DHC subgroups. Overjet was associated with self-esteem, while OVB was correlated with dental self-confidence and overall assessment of orofacial aesthetics. Skeletal variables were not associated with the studied domains. The PIDAQ was significantly positively correlated with the IOTN-AC and negatively correlated with the RSES.</p><p><strong>Conclusions: </strong>The perception of malocclusion severity differs between patients and clinicians, highlighting the need to consider patients' values when defining orthodontic goals. Overjet and OVB are clinical variables that can influence the psychosocial domain in adolescents.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"63 3","pages":"617-627"},"PeriodicalIF":4.3,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148444789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}