Dental and Medical Problems最新文献

{"title":"Impact of high-consumption beverages on the color, and surface roughness and microhardness of resin-matrix ceramics.","authors":"Ebele Adaobi Silva, Anselmo Agostinho Simionato, Olívia Breda Moss, Adriana Cláudia Lapria Faria, Renata Cristina Silveira Rodrigues, Ricardo Faria Ribeiro","doi":"10.17219/dmp/171320","DOIUrl":"https://doi.org/10.17219/dmp/171320","url":null,"abstract":"<p><strong>Background: </strong>Resin-matrix ceramics have been developed to combine the high esthetics of ceramics with the mechanical properties of composite resin. The surface changes of these materials when exposed to highly consumed beverages are still not fully elucidated and need further research.</p><p><strong>Objectives: </strong>The aim of the present study was to evaluate the color stability, and surface roughness and microhardness of a polymer-infiltrated ceramic network (PICN) (VITA ENAMIC® - VE) and a resin nanoceramic (Ambarino® High-Class - AH), used to obtain computer-aided design/computer-aided manufacturing (CAD/CAM) restorations, after immersion in high-consumption beverages.</p><p><strong>Material and methods: </strong>A total of 96 specimens were prepared (n = 48 per group - VE and AH), further subdivided into 6 groups (n = 8) according to the beverage in which they were immersed. The color change (ΔE00), surface roughness (Ra) and microhardness (KHN) measurements were made before and after immersion in the beverages.</p><p><strong>Results: </strong>The materials presented significant differences in ΔE00 when immersed in distilled water (p = 0.043), coffee (p = 0.010) and red wine (p < 0.001). Acceptable values for ΔE00 were recorded for distilled water and the energy drink with regard to AH, and for the energy drink and orange juice with regard to VE. Regarding the Ra data, the VE samples showed a difference after immersion in all the tested beverages, while AH differed only when immersed in distilled water and the energy drink. Immersion in the beverages seemed to reduce KHN in the tested materials, although significant differences were detected only in the VE samples from the energy drink (p < 0.001) and orange juice (p < 0.001) groups.</p><p><strong>Conclusions: </strong>Based on the results, it can be concluded that the beverages tested may affect the esthetics and surface characteristics of the materials tested.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"62 2","pages":"299-307"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circulating biomarkers of nitrosative stress, protein glycoxidation and inflammation in maxillofacial surgery patients treated with titanium implants.","authors":"Bożena Antonowicz, Jan Borys, Anna Zalewska, Małgorzata Żendzian-Piotrowska, Kamila Łukaszuk, Łukasz Woźniak, Mariusz Szuta, Mateusz Maciejczyk","doi":"10.17219/dmp/188863","DOIUrl":"10.17219/dmp/188863","url":null,"abstract":"<p><strong>Background: </strong>Titanium (Ti) biomaterials are widely used in the surgical management of maxillofacial trauma, in oncology and orthognathic surgery. Although Ti is considered highly biocompatible, adverse reactions at the implant site have been reported in numerous clinical studies. However, the influence of Ti mandibular implants on glutathione metabolism, nitrosative stress and systemic inflammation has not been investigated to date.</p><p><strong>Objectives: </strong>The study aimed to evaluate the acute (short-term) effects of Ti mandibular implants on the circulating biomarkers of the antioxidant defense system, on oxidative and nitrosative stress, as well as the inflammatory response of the blood plasma/erythrocytes, in maxillofacial surgery patients compared to the control group.</p><p><strong>Material and methods: </strong>The experimental group consisted of 40 patients with bilateral mandibular fractures, who received osteosynthesis treatment with the use of Ti-6Al-4V alloy miniplates and screws. The control group comprised 40 ageand gender-matched patients who were qualified for the surgical treatment of craniofacial defects through bimaxillary osteotomy.</p><p><strong>Results: </strong>An increase in the activity of pro-oxidant enzymes (↑ nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX), ↑ xanthine oxidase (XO)), impaired glutathione metabolism (↓ total glutathione, ↑ oxidized glutathione (GSSG), ↓ reduced glutathione (GSH), ↓ redox status), higher levels of oxidative stress (↓ total thiols, ↑ malondialdehyde (MDA), ↑ lipid hydroperoxides (LOOHs)), ↓ total antioxidant status (TAS)), carbonyl stress (↑ dityrosine, ↑ N-formylkynurenine) and nitrosative stress (↑ nitric oxide (NO), ↑ S-nitrosothiols, ↑ peroxynitrite, ↑ nitrotyrosine), as well as an intensified systemic inflammatory response (↑ interleukin (IL)-1β, ↑ IL-6), were observed in maxillofacial surgery patients.</p><p><strong>Conclusions: </strong>Despite the fact that the study examined only the circulating biomarkers of redox balance and inflammation, the results suggest that a systemic inflammatory response can be triggered by local immune reactions. Systemic inflammation and oxidative stress may stem from an early adaptive immune response to foreign objects in the body. Although further research is required, the removal of the existing Ti mandibular implants should be considered.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":" ","pages":"225-236"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of facial soft tissue thickness in subjects with different malocclusions according to the lateral cephalograms of an Iranian adult population.","authors":"Milad Ali Asgharlou, Mahsa Esfehani, Maryam Tofangchiha, Amir Javadi, Nima Sheikhdavoodi, Zahra Yousefi, Rodolfo Reda, Luca Testarelli","doi":"10.17219/dmp/171501","DOIUrl":"https://doi.org/10.17219/dmp/171501","url":null,"abstract":"<p><strong>Background: </strong>Facial characteristics are determined by the thickness of facial soft tissue and parameters of the dentoskeletal system.</p><p><strong>Objectives: </strong>The aim of the study was to compare the soft tissue thickness in individuals with different malocclusions, based on their lateral cephalograms.</p><p><strong>Material and methods: </strong>In this retrospective study, 285 lateral cephalograms of 141 males and 144 females aged between 18 and 40 years were evaluated in the following 4 groups of malocclusions: class I (n = 72); class II division 1 (n = 71); class II division 2 (n = 72); and class III (n = 70). Linear measurements of the soft tissue thickness were obtained at 9 facial midline landmarks. Angular measurements were made by calculating the ANB angle and the inclination angle of upper central incisors. The data was statistically analyzed using the χ2 test, the Shapiro-Wilk test, the t-test, analysis of variance (ANOVA), Tukey's test, and Pearson's correlation.</p><p><strong>Results: </strong>A comparison of the soft tissue thickness revealed that male subjects demonstrated greater thickness than female subjects. This difference was statistically significant at all points in the skeletal class III individuals (p < 0.05). Different skeletal classes demonstrated significant differences in the soft tissue thickness at the subnasale, stomion, labrale inferius, labiomentale, and menton (p < 0.05).</p><p><strong>Conclusions: </strong>Males exhibited a greater facial soft tissue thickness than females. A statistically significant difference in the soft tissue thickness was observed among the different skeletal classes, particularly at regions located farther from the underlying bone. The class III individuals revealed an increased upper lip thickness and a decreased lower lip thickness. A decrease in the upper lip thickness and an increase in the lower lip thickness were observed in the class II individuals. This pattern suggests that the underlying skeletal discrepancy is being concealed.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"62 2","pages":"255-263"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the relationship between sleep bruxism, reported pain and headache, selected health factors, and general health conditions among temporomandibular disorder patients: A preliminary report.","authors":"Sylwia Orzeszek, Helena Martynowicz, Joanna Smardz, Katarzyna Kresse-Walczak, Anna Wojakowska, Wojciech Bombała, Marta Bort, Mieszko Wieckiewicz","doi":"10.17219/dmp/192824","DOIUrl":"https://doi.org/10.17219/dmp/192824","url":null,"abstract":"<p><strong>Background: </strong>Temporomandibular disorders (TMD) constitute a serious health problem that can have a negative effect on patients' lives, impair work performance, and result in work absences and restrictions in daily activities. Therefore, it is of great importance not only to employ appropriate diagnostic and therapeutic procedures in the case of patients suffering from TMD and/or sleep bruxism (SB), but also to analyze the impact of different medical and non-medical factors on the occurrence of such conditions, as the proper modification of these factors may mitigate the severity of patients' symptoms.</p><p><strong>Objectives: </strong>The present preliminary study aimed to assess the relationship between SB, reported pain and headache, selected health factors, and general health conditions among TMD patients.</p><p><strong>Material and methods: </strong>A total of 114 patients from the Outpatient Clinic for Temporomandibular Disorders in Wroclaw, Poland, had single-night video-polysomnography (PSG) performed. The patients completed questionnaires about their pain experience, headache and health condition, including the presence or history of diseases such as hypothyroidism, arterial hypertension, cancer, diabetes, myocardial infarction, stroke, gastroesophageal reflux disease (GERD), and were asked about the frequency of alcohol consumption, smoking, caffeine use, and physical activity. The collected data was statistically analyzed.</p><p><strong>Results: </strong>It seems that among patients with TMD, a history of cancer and GERD may have an impact on the experience of pain and headache. Smoking was significantly associated with the occurrence and intensity of SB.</p><p><strong>Conclusions: </strong>A few habits, health factors and general health conditions of patients with TMD are associated with SB, and reported pain and headache, but this relationship requires further research conducted on a larger study group.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"62 2","pages":"393-399"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the antibacterial and antibiofilm activity of Zataria multiflora in comparison with chlorhexidine, using a tooth model: A preliminary study.","authors":"Aida Mehdipour, Raziye Pourreisi, Hossein Amini-Khoei, Saeed Shams","doi":"10.17219/dmp/150652","DOIUrl":"https://doi.org/10.17219/dmp/150652","url":null,"abstract":"<p><strong>Background: </strong>The formation of biofilm on the tooth surface can lead to the dissolution of the enamel minerals and the onset of tooth decay. Natural compounds may prove to be effective in the prevention of biofilm formation.</p><p><strong>Objectives: </strong>The present study aimed to evaluate the antibacterial and antibiofilm activity of the Zataria multiflora ethanolic extract in comparison with chlorhexidine, using a novel tooth model.</p><p><strong>Material and methods: </strong>The study used teeth extracted due to orthodontic treatment or impacted wisdom tooth surgery. Saliva was collected from a volunteer 12 h after tooth brushing, before the test, and it was used freshly. The teeth were placed in 5 test tubes containing a broth medium and serial dilutions of the Z. multiflora extract (50, 25, 12.5, 6.25, and 3.125 mg/mL). A total of 1 mL of the collected saliva was added to each test tube. The growth of microorganisms in the medium was examined visually and the antibiofilm activity of the plant extract was assessed after 72 h, using a spatula. The results were compared with those of positive and negative controls.</p><p><strong>Results: </strong>Considerable turbidity was observed in the positive control tube containing a tooth, the culture medium and saliva, indicating that the conditions were favorable for the growth of oral flora. No bacterial growth or biofilm formation were observed in the test tubes containing ≥25 mg/mL of the plant extract.</p><p><strong>Conclusions: </strong>The study results indicated that the Z. multiflora extract had an excellent inhibitory effect against microorganisms and plaque formation in the tooth model, suggesting a suitable substitute for chlorhexidine. However, further studies in this area are recommended.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"62 2","pages":"293-298"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of the pharmacotherapy of general diseases on the severity of symptoms of temporomandibular disorders.","authors":"Katarzyna Grad, Zuzanna Kazibudzka, Małgorzata Pihut, Aneta Wieczorek","doi":"10.17219/dmp/175417","DOIUrl":"https://doi.org/10.17219/dmp/175417","url":null,"abstract":"<p><strong>Background: </strong>Temporomandibular disorders (TMD) constitute a heterogeneous group of conditions affecting the temporomandibular joints (TMJs) and the surrounding tissues. The etiology of these anomalies has been extensively discussed due to their multifactorial and diverse nature; however the influence of many factors remains ambiguous. Temporomandibular disorders may be manifested as pain or in a painless form, characterized by acoustic symptoms in TMJs or their dysfunction. The presence of a causal relationship between the use of medications for chronic diseases and TMD symptoms can simplify the diagnostic and therapeutic approach in TMD treatment.</p><p><strong>Objectives: </strong>The aim of the study was to verify the existence of and assess the correlation between the usage of pharmacotherapy in chronic diseases and the occurrence and severity of TMD symptoms.</p><p><strong>Material and methods: </strong>This retrospective study was based on the analysis of 252 questionnaires completed by patients who had previously reported to the University Dental Clinic in Krakow, Poland, due to the occurrence of TMD symptoms. The patients were categorized into 4 subgroups, depending on the type of drugs taken: endocrine; cardiological; psychotropic; and other. Data was subjected to statistical analysis.</p><p><strong>Results: </strong>In the tested group, an association between the usage of endocrine drugs and the risk of headaches was observed. The patients taking cardiological drugs exhibited a reduced likelihood of experiencing difficulties in opening the mouth wide as compared to those under treatment for other reasons. However, no significant impact of the drugs on the intensity of TMD pain symptoms was observed. Furthermore, no correlation was found between the medications taken and the occurrence of clicking in TMJ and behaviors in the form of clenching and/or grinding of the teeth.</p><p><strong>Conclusions: </strong>The pharmacotherapy of chronic diseases in TMD patients might be associated with an increased risk of headaches. Nonetheless, there were no statistically significant differences between the types of drugs taken with regard to the intensity of TMD pain symptoms, as well as the presence of clicking and behaviors in the form of clenching and/or grinding of the teeth.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"62 2","pages":"247-253"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global co-occurrence of bruxism and temporomandibular disorders: A meta-regression analysis.","authors":"Grzegorz Zieliński, Beata Pająk-Zielińska, Agnieszka Pająk, Marcin Wójcicki, Monika Litko-Rola, Michał Ginszt","doi":"10.17219/dmp/201376","DOIUrl":"10.17219/dmp/201376","url":null,"abstract":"<p><strong>Background: </strong>Bruxism and temporomandibular disorders (TMD) are closely related, yet the relationship between bruxism and TMD remains one of the most debated topics in the literature.</p><p><strong>Objectives: </strong>The aim of the study was to estimate the overall proportions of the co-occurrence of bruxism and TMD, and the prevalence of TMD in individuals with bruxism by continent. Additionally, factors that have an influence on these proportions, including geographical region, sex and other demographic variables, were analyzed.</p><p><strong>Material and methods: </strong>A synthesis of data from 6 meta-analyses and systematic reviews published up to October 2024 was conducted. The data was extracted from 30 studies that analyzed 31 populations, with a total of 37,680 participants, of whom 5,117 were diagnosed with both bruxism and TMD. The analyses were conducted using the R statistical language.</p><p><strong>Results: </strong>The global co-occurrence of bruxism and TMD was 17%, with significant differences observed between continents. In North America, the co-occurrence of these 2 conditions was 70%, followed by 24% in South America, 14% in Europe and 9% in Asia. The analysis revealed that the sex of the participants was a significant factor, as higher proportions of female participants in a study sample increased the likelihood of the co-occurrence of TMD and bruxism. The mean prevalence of TMD among patients with bruxism was 63.5%, with the highest rate observed in North America (98.3%) and the lowest in Asia (53.9%).</p><p><strong>Conclusions: </strong>The meta-analysis underscores the high prevalence of TMD in individuals with bruxism, highlighting significant geographical variations in the co-occurrence of these conditions. A 1% increase in the proportion of female participants in a study group was associated with a 4.4% rise in the probability of the co-occurrence of TMD and bruxism. These findings suggest that temporal factors and the average age of participants did not significantly contribute to observed variability across studies. The results underscore the importance of geographical and demographic factors in understanding the interplay between bruxism and TMD.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":" ","pages":"309-321"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indications for antibiotic prophylaxis, and algorithms for dental management after open and endovascular surgery in patients with aortic diseases.","authors":"Dorota Łyko-Morawska, Michał Serafin, Łukasz Szkółka, Maryam Kazelka, Millena Levin, Emila Senderek, Agnieszka Święszek, Mariusz Szuta, Wacław Kuczmik","doi":"10.17219/dmp/193485","DOIUrl":"https://doi.org/10.17219/dmp/193485","url":null,"abstract":"<p><p>As the population of patients with aortic prostheses continues to grow, it becomes increasingly vital to implement comprehensive and rigorous protocols for antibiotic prophylaxis during dental procedures. That ensures strict adherence to the updated guidelines in order to effectively prevent the risk of life-threatening infections associated with vascular grafts and stent-grafts, thus safeguarding patient outcomes over the long term.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"62 2","pages":"201-207"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revisiting and rethinking on staging (severity and complexity) periodontitis from the new classification system: A critical review with suggestions for adjustments and a proposal of a new flowchart.","authors":"Gustavo Vicentis De Oliveira Fernandes, Juliana Campos Hasse Fernandes","doi":"10.17219/dmp/192121","DOIUrl":"https://doi.org/10.17219/dmp/192121","url":null,"abstract":"<p><p>This critical review revisited the new classification system for periodontitis, specifically for staging, suggesting modifications and introducing a new flowchart for a better clinical evaluation. It evaluated articles published between 2018 and 2024 in the English language, which had an educational motivation focused on staging periodontitis. The PubMed/MEDLINE, Web of Science and Embase databases were used to retrieve the articles. The focus questions involved the analysis of all parameters for staging periodontitis.A total of 836 articles were initially found, of which 388 duplicates were excluded, 448 were evaluated by title and abstract, 26 articles were followed for full-text reading, and 6 articles were finally included in this critical review (k = 0.98). All articles included detailed parameters and steps referring to diagnosing periodontitis. Therefore, it was possible to observe instability and 'gray zones' in the staging step, which was due to the lack of priority and an organized order sequence.This review suggests the severity parameters cannot be overcome by the complexity parameters, following a cumulative sequence: clinical attachment loss (CAL) (1st); radiographic bone loss (RBL) (2nd); tooth loss due to periodontitis (TLP) (3rd); and then the complexity parameters. An exception must be permitted only for the complexity factors between Stages III and IV that can change the initial Stage (III or IV) obtained through the severity analysis, but only between the 2 stages. Moreover, for patients without tooth loss or with TLP ≤ 4 (without the need for complex rehabilitation), and presenting any type of drifting or flaring or a secondary traumatic occlusion, there is no justification for moving the diagnosis from Stage III to Stage IV.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"62 2","pages":"371-391"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of phosphorylated chitosan and carbodiimide on the surface wettability, surface free energy and surface morphology of the eroded dentin.","authors":"Mirian Saavedra Lopes Ururahy, Erick Silva Barbosa, Rafaela Manente, Ana Paula Ramos, Antônio Eduardo Miller Crotti, Silmara Aparecida Milori Corona","doi":"10.17219/dmp/170245","DOIUrl":"https://doi.org/10.17219/dmp/170245","url":null,"abstract":"<p><strong>Background: </strong>Biomodifiers can reinforce the collagen matrix, improving the biomechanical and biochemical properties of dentin.</p><p><strong>Objectives: </strong>The present study aimed to evaluate how 2.5% phosphorylated chitosan (P-Chi) and 0.5 mol/L carbodiimide (EDC) affect the surface wettability, surface free energy and surface morphology of the eroded dentin.</p><p><strong>Material and methods: </strong>Bovine tooth specimens (N = 144) were randomly divided into 6 groups according to the dentin substrate (sound or eroded) and surface treatment (2.5% P-Chi, 0.5 mol/L EDC or no biomodification (control)). Half of the specimens (n = 72) were submitted to erosive challenge by immersion in 0.3% citric acid (pH 3.2) for 2 h. For the surface wettability analysis (n = 12), the contact angles between the dentin surface and the 3M™ Scotchbond™ Universal adhesive were measured with a goniometer. For the surface free energy analysis (n = 3), the contact angles between the dentin surface and 3 organic solvents of distinct polarities (water, formamide and diiodomethane) were recorded. Surface morphology (n = 3) was analyzed with the use of scanning electron microscopy (SEM). The data was statistically analyzed using the two-way analysis of variance (ANOVA) (α = 0.05).</p><p><strong>Results: </strong>Neither 2.5% P-Chi nor 0.5 mol/L EDC influenced the dentin surface wettability (p > 0.05). Surface free energy decreased in the eroded substrate after biomodification with EDC (p < 0.05). Biomodification with P-Chi demineralized the dentin surface and increased the dentin tubule embouchure.</p><p><strong>Conclusions: </strong>It can be concluded that 2.5% P-Chi and 0.5 mol/L EDC did not impact the surface wettability of the eroded dentin. However, EDC promoted lower surface free energy, while P-Chi altered surface morphology, causing demineralization and the opening of dentin tubules.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"62 2","pages":"275-283"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}