Diabetes technology & therapeutics最新文献

{"title":"Advances in Exercise and Nutrition as Therapy in Diabetes.","authors":"Dessi P Zaharieva, Dorsa Shakeri, Lauren V Turner, Michael C Riddell","doi":"10.1089/dia.2025.8809.dpz","DOIUrl":"https://doi.org/10.1089/dia.2025.8809.dpz","url":null,"abstract":"","PeriodicalId":11159,"journal":{"name":"Diabetes technology & therapeutics","volume":"27 S1","pages":"S126-S140"},"PeriodicalIF":5.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immune Intervention and Replacement Therapies in Type 1 Diabetes.","authors":"Laura M Jacobsen, Nataša Bratina, Desmond Schatz","doi":"10.1089/dia.2025.8815.lmj","DOIUrl":"https://doi.org/10.1089/dia.2025.8815.lmj","url":null,"abstract":"","PeriodicalId":11159,"journal":{"name":"Diabetes technology & therapeutics","volume":"27 S1","pages":"S200-S207"},"PeriodicalIF":5.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on Preechasuk et al.: Switching from Intermittently-Scanned Continuous Glucose Monitoring to Real-Time Continuous Glucose Monitoring with a Predictive Urgent Low Soon Alert Reduces Exposure to Hypoglycemia.","authors":"Alexander Seibold","doi":"10.1089/dia.2024.0345","DOIUrl":"10.1089/dia.2024.0345","url":null,"abstract":"","PeriodicalId":11159,"journal":{"name":"Diabetes technology & therapeutics","volume":" ","pages":"e243-e244"},"PeriodicalIF":5.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetes Technology and Therapy in the Pediatric Age Group.","authors":"David M Maahs, Priya Prahalad, Darja Šmigoc Schweiger, Shlomit Shalitin","doi":"10.1089/dia.2025.8808.dmm","DOIUrl":"https://doi.org/10.1089/dia.2025.8808.dmm","url":null,"abstract":"","PeriodicalId":11159,"journal":{"name":"Diabetes technology & therapeutics","volume":"27 S1","pages":"S103-S125"},"PeriodicalIF":5.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Closed-Loop, Artificial Intelligence-Based Decision Support Systems, and Data Science.","authors":"Revital Nimri, Moshe Phillip, Mark A Clements, Boris Kovatchev","doi":"10.1089/dia.2025.8805.rev","DOIUrl":"https://doi.org/10.1089/dia.2025.8805.rev","url":null,"abstract":"","PeriodicalId":11159,"journal":{"name":"Diabetes technology & therapeutics","volume":"27 S1","pages":"S64-S78"},"PeriodicalIF":5.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insulin Delivery Hardware: Pumps and Pens.","authors":"Rayhan Lal, Lalantha Leelarathna","doi":"10.1089/dia.2025.8803.rl","DOIUrl":"https://doi.org/10.1089/dia.2025.8803.rl","url":null,"abstract":"","PeriodicalId":11159,"journal":{"name":"Diabetes technology & therapeutics","volume":"27 S1","pages":"S31-S40"},"PeriodicalIF":5.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Technology and Pregnancy.","authors":"Jennifer M Yamamoto, Helen R Murphy","doi":"10.1089/dia.2025.8807.jmy","DOIUrl":"https://doi.org/10.1089/dia.2025.8807.jmy","url":null,"abstract":"","PeriodicalId":11159,"journal":{"name":"Diabetes technology & therapeutics","volume":"27 S1","pages":"S92-S102"},"PeriodicalIF":5.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Digital Health Technology to Prevent and Treat Diabetes.","authors":"Mark A Clements, Neal Kaufman, Eran Mel","doi":"10.1089/dia.2025.8806.mcl","DOIUrl":"https://doi.org/10.1089/dia.2025.8806.mcl","url":null,"abstract":"","PeriodicalId":11159,"journal":{"name":"Diabetes technology & therapeutics","volume":"27 S1","pages":"S79-S91"},"PeriodicalIF":5.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhaled Technosphere Insulin Plus Insulin Degludec for Adults with Type 1 Diabetes: The INHALE-3 Extension Study.","authors":"Roy W Beck, Ryan J Bailey, Klara R Klein, Grazia Aleppo, Carol J Levy, Jamie Diner, Christopher Jacobson, Camilla M Levister, Peter Calhoun, Katrina J Ruedy, Irl B Hirsch","doi":"10.1089/dia.2024.0582","DOIUrl":"https://doi.org/10.1089/dia.2024.0582","url":null,"abstract":"<p><p><b><i>Background:</i></b> Postmeal hyperglycemia is difficult to avoid even with automated insulin delivery (AID) due to the delayed effect of subcutaneously administered rapid-acting insulin analogs. Inhaled technosphere insulin (TI, Afrezza®) has a more rapid onset of action with the potential to reduce the postmeal glucose rise. We evaluated the effects of a regimen of TI and degludec over 30 weeks. <b><i>Methods:</i></b> In total, 123 adults with type 1 diabetes (T1D) participated in a 17-week multicenter randomized controlled trial comparing a regimen of TI plus insulin degludec versus usual care, which consisted predominantly of AID or multiple daily insulin injections (MDI). Interested participants in the TI-degludec group continued this regimen for an additional 13 weeks, with no scheduled visits prior to a final visit at 30 weeks to approximate real-world care. <b><i>Results:</i></b> Of the 62 participants in the TI-degludec group, 58 completed the 17-week visit and 45 continued into the extension phase. Prior to the study, 44% were using AID, 9% a sensor-augmented pump without automation, and 47% MDI. Mean HbA1c was 7.6% ± 1.0% at baseline, 7.6% ± 1.0% at 17 weeks, and 7.4% ± 1.0% at 30 weeks. Mean HbA1c change from 17 weeks to 30 weeks was -0.21% (95% confidence interval -0.33% to -0.09%, <i>P</i> < 0.001). HbA1c was <7.0% in 21% at baseline, 30% at 17 weeks, and 42% at 30 weeks. Mean time in range 70-180 mg/dL was 52% ± 18% at baseline, 53% ± 20% at 17 weeks, and 54% ± 20% at 30 weeks. Mean percent time <54 mg/dL was 0.4% ± 0.6%, 0.4% ± 0.8%, and 0.6% ± 1.0%, respectively. Mean total daily TI dose at 30 weeks was 53 ± 31 U/day, which was about twice the total daily rapid-acting insulin analog dose of 24 ± 12 U/day at baseline prior to switching to TI. <b><i>Conclusions:</i></b> HbA1c levels were sustained over 30 weeks using a TI-degludec regimen after switching from AID or MDI. TI should be considered an option for people with T1D.</p>","PeriodicalId":11159,"journal":{"name":"Diabetes technology & therapeutics","volume":"27 3","pages":"170-178"},"PeriodicalIF":5.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toward Automation: The Road Traveled and Road Ahead for Integrating Automated Insulin Delivery into Inpatient Care.","authors":"Michael S Hughes, Francisco J Pasquel, Georgia M Davis, Rayhan A Lal, Bruce A Buckingham, Charlotte K Boughton, Sue A Brown, Lia Bally","doi":"10.1089/dia.2024.0343","DOIUrl":"10.1089/dia.2024.0343","url":null,"abstract":"<p><p>The introduction of automated insulin delivery (AID) systems represents a significant advancement in diabetes care, offering substantial benefits in outpatient settings. Although clinical studies suggest that these systems can also help improve glycemic control in acutely ill patients, several barriers remain for the actual implementation and use of these technologies in clinical practice. Three main contexts for inpatient use are addressed, including: (a) continuation of personal AID systems, (b) initiation of AID during hospitalization, and (c) initiation of AID systems at discharge. A research road map with immediate to long-term actions is presented. Initially, it calls for clinical studies assessing in-hospital efficacy, safety, and utility, addressing specific patient needs and health care operational impacts. Midterm, it focuses on practical integration, simplifying AID use, ensuring electronic health record compatibility, clarifying regulatory uncertainties, and supporting health care professionals and patients. Long-term goals include system optimizations and policy advocacy for in-hospital AID use.</p>","PeriodicalId":11159,"journal":{"name":"Diabetes technology & therapeutics","volume":" ","pages":"217-242"},"PeriodicalIF":5.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11971560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}