Current Opinion in Psychiatry最新文献_第3页

An international initiative to implement recommendations for a lower therapeutic range of maintenance lithium in older adults with bipolar disorder. 在老年双相情感障碍患者中实施低治疗范围维持性锂建议的国际倡议。

IF 5.9 2区医学

Current Opinion in Psychiatry Pub Date : 2026-09-01 Epub Date: 2026-07-01 DOI: 10.1097/YCO.0000000000001105

Kenneth I Shulman, Paula V Nunes, Lei Fu, Lisa T Eyler

{"title":"An international initiative to implement recommendations for a lower therapeutic range of maintenance lithium in older adults with bipolar disorder.","authors":"Kenneth I Shulman, Paula V Nunes, Lei Fu, Lisa T Eyler","doi":"10.1097/YCO.0000000000001105","DOIUrl":"10.1097/YCO.0000000000001105","url":null,"abstract":"Purpose of review: The aim of this study was to promote the universal recommendation that lithium carbonate remains the first-choice mood stabilizer for maintenance treatment of older adults with bipolar disorder (OABD) as concluded in a Delphi survey of the International Society for Bipolar Disorders (ISBD) as well as all other official guidelines.Recent findings: Prescriptions of lithium have continued to decline in OABD worldwide despite these recommendations and in the face of evidence for its effectiveness as a mood stabilizer and lithium's potential for suicide prevention and neuroprotection from dementia. This study describes the results of a recent literature review of the role of lithium in OABD, finding further support from the recommended therapeutic range of 0.4-0.8 mmol/l for those aged 60-79 years and 0.4-0.7 mmol/l for those 80 and over, and summarizing prescribing considerations. We also provide evidence of the practicality of measuring and reporting age-specific ranges from a laboratory medicine perspective. Finally, we report on an international initiative of the ISBD OABD task force that aims to implement the lower recommended therapeutic ranges for maintenance lithium treatment as reported by laboratories around the world.Summary: Initial efforts in Canada have resulted in the implementation of widespread changes in laboratory reporting. International efforts to implement separate and lower therapeutic ranges for lithium in OABD are continuing; so far, 18 dissemination attempts have yielded three successful implementations. This initiative aims to provide well tolerated and effective lithium treatment for OABD while reducing the risk of toxicity in this vulnerable group of patients.","PeriodicalId":11022,"journal":{"name":"Current Opinion in Psychiatry","volume":" ","pages":"406-411"},"PeriodicalIF":5.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148561218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond mood: alcohol and substance use older adults with bipolar disorder. 情绪之外：患有双相情感障碍的老年人酒精和物质使用。

IF 5.9 2区医学

Current Opinion in Psychiatry Pub Date : 2026-09-01 Epub Date: 2026-04-15 DOI: 10.1097/YCO.0000000000001090

Luisa de Siqueira Rotenberg, Hudson Reddon, Paula Villela Nunes

{"title":"Beyond mood: alcohol and substance use older adults with bipolar disorder.","authors":"Luisa de Siqueira Rotenberg, Hudson Reddon, Paula Villela Nunes","doi":"10.1097/YCO.0000000000001090","DOIUrl":"10.1097/YCO.0000000000001090","url":null,"abstract":"Purpose of review: Substance use and substance use disorders (SUD) are common comorbidities in bipolar disorder (BD) and remain clinically consequential in older-age bipolar disorder (OABD), where medical vulnerability increases and detection may be more challenging. This review summarizes epidemiologic and clinical findings on substance use in OABD and highlights implications for assessment and management.Recent findings: Recent longitudinal studies suggest that fluctuations in alcohol consumption, even when modest, are associated with poorer mood stability and functioning in BD, while worsening mood symptoms do not consistently predict subsequent increases in alcohol use, complicating simple self-medication models. Population-based studies continue to demonstrate elevated rates of SUD in individuals with BD compared with age-matched controls, with risk concentrated among those with earlier-onset illness. Large cohort data link SUD to increased mortality and greater cumulative medical burden. Cannabis use has also been consistently associated with worsened clinical outcomes, including greater symptom severity, poorer treatment adherence, and increased hospitalization risk.Summary: Substance use and SUD substantially worsen psychiatric and medical outcomes in OABD. Routine, repeated screening and integrated treatment approaches addressing psychiatric symptoms, medical comorbidity, cognition, and social context are essential to reduce long-term morbidity and improve functional outcomes in later life.","PeriodicalId":11022,"journal":{"name":"Current Opinion in Psychiatry","volume":" ","pages":"412-417"},"PeriodicalIF":5.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147765092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Harmful behaviours and suicide in later life bipolar disorder. 双相情感障碍后期的有害行为和自杀。

IF 5.9 2区医学

Current Opinion in Psychiatry Pub Date : 2026-09-01 Epub Date: 2026-06-15 DOI: 10.1097/YCO.0000000000001106

Juliano Flávio Rubatino Rodrigues, Lívia Peregrino Rodrigues, Gerardo Maria de Araújo Filho

{"title":"Harmful behaviours and suicide in later life bipolar disorder.","authors":"Juliano Flávio Rubatino Rodrigues, Lívia Peregrino Rodrigues, Gerardo Maria de Araújo Filho","doi":"10.1097/YCO.0000000000001106","DOIUrl":"10.1097/YCO.0000000000001106","url":null,"abstract":"Purpose of review: Harmful behaviours and suicidality are often linked to mental disorders, making it crucial to gain a deeper understanding of these issues. One significant area of focus is bipolar disorder in older adults, a condition that requires further exploration to better address its impact on this age group.Recent findings: Longer hospital stays increased harmful behaviour among older adults with bipolar disorder. Older adults with bipolar disorder have lower suicide rates than younger individuals, possibly due to heightened risks shortly after diagnosis, so, it makes it important to pay attention to cases of late-onset bipolar disorder. Early-onset bipolar disorder is often genetically influenced, while late-onset bipolar disorder was more affected by environmental factors, with cognitive impairments leading to poorer functioning. The early years following a diagnosis of dementia associated with bipolar disorder show a higher risk of suicide.Summary: Individuals experiencing manic episodes of bipolar disorder often display a heightened propensity for harmful behaviours. In contrast, during depressive episodes, these individuals are at an increased risk of contemplating or attempting suicide. Research highlights that the threat of suicide is particularly pronounced in the initial years after a bipolar disorder diagnosis, underscoring the critical need for vigilant monitoring during this vulnerable period. This concern is especially significant for cases of late-onset bipolar disorder in older adults, where the unique complexities of age may compound the challenges and risks associated with the condition.","PeriodicalId":11022,"journal":{"name":"Current Opinion in Psychiatry","volume":" ","pages":"418-424"},"PeriodicalIF":5.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148263807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emerging insights into the physical health burden of personality disorders. 对人格障碍的身体健康负担的新见解。

IF 5.9 2区医学

Current Opinion in Psychiatry Pub Date : 2026-09-01 Epub Date: 2026-07-30 DOI: 10.1097/YCO.0000000000001110

Ivona Šimunović Filipčić, Igor Filipčić, Ivana Jurčić Čulina, Darko Marčinko, Nenad Jakšić

{"title":"Emerging insights into the physical health burden of personality disorders.","authors":"Ivona Šimunović Filipčić, Igor Filipčić, Ivana Jurčić Čulina, Darko Marčinko, Nenad Jakšić","doi":"10.1097/YCO.0000000000001110","DOIUrl":"https://doi.org/10.1097/YCO.0000000000001110","url":null,"abstract":"Purpose of review: This review summarizes recent evidence on the physical health burden associated with personality disorders (PDs), focusing on physical comorbidity and multimorbidity, physical symptoms, and premature mortality.Recent findings: Accumulating evidence indicates that individuals with PDs experience markedly elevated rates of chronic physical illness, multimorbidity, and premature mortality. Large-scale cohort studies demonstrate increased risks of cardiovascular disease, myocardial infarction, stroke, and all-cause mortality emerging early in life. Recent investigations further show that nearly half of individuals with PDs meet criteria for chronic physical multimorbidity. Borderline personality disorder (BPD) appears especially associated with broad somatic burden, including pain-related conditions, accompanied by substantially reduced life expectancy. Dimensional approaches additionally suggest that PD severity and maladaptive domains, particularly Negative Affectivity, are independently linked to greater somatic burden. Current evidence supports multifactorial mechanisms involving maladaptive health behaviors, chronic stress-system dysregulation, systemic inflammation, metabolic changes, and healthcare disparities.Summary: PDs are associated with a substantial yet underrecognized physical health burden. Converging evidence supports a systemic model in which personality pathology contributes to increased somatic (multi)morbidity and premature mortality through interacting behavioral, biological, developmental, and healthcare-related mechanisms. Integrating physical and mental healthcare may help reduce excess morbidity and mortality in this population.","PeriodicalId":11022,"journal":{"name":"Current Opinion in Psychiatry","volume":"39 5","pages":"357-363"},"PeriodicalIF":5.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Orthorexia nervosa: assessment, prevalence, high-risk groups, co-occurring features and management. 神经性厌食症：评估、患病率、高危人群、共发特征及处理。

IF 5.9 2区医学

Current Opinion in Psychiatry Pub Date : 2026-08-27 DOI: 10.1097/YCO.0000000000001113

Anna Keski-Rahkonen, Leyla Laçin, Gizem Ağir

{"title":"Orthorexia nervosa: assessment, prevalence, high-risk groups, co-occurring features and management.","authors":"Anna Keski-Rahkonen, Leyla Laçin, Gizem Ağir","doi":"10.1097/YCO.0000000000001113","DOIUrl":"https://doi.org/10.1097/YCO.0000000000001113","url":null,"abstract":"Purpose of review: This review synthesizes research on orthorexia nervosa published in 2025 and early 2026.Recent findings: Orthorexia nervosa is characterized by an excessive focus on healthy eating. Widely used measures, particularly the ORTO-15, have been criticized for poor reliability, prompting the development of new assessment instruments. Recent prevalence estimates of orthorexia nervosa vary widely. Meta-analyses based on ORTO-15 assessment in highly heterogeneous settings suggest an overall prevalence of 27.5%, with men and women equally at risk. However, more recent studies indicate a substantially lower prevalence, 0.5-1.5% for orthorexia nervosa and 7.5-15% for elevated orthorexic tendencies. High-risk groups include dietitians, nutrition and sport science students, athletes, and individuals required to monitor their diet. Dietary patterns involving plant-based eating are associated with orthorexia. Other factors associated with increased risk include societal stressors, such as pandemics and climate concerns, social media use, particularly image-based platforms, and psychological traits, such as perfectionism, emotion regulation difficulties, obsessive-compulsive features, alexithymia, and autistic traits. Evidence on long-term outcomes and treatment remains limited, although psychoeducation appears promising.Summary: Orthorexia nervosa is an eating disorder that also reflects broader nutritional, sociocultural, and moral trends. Longitudinal research is needed on its course and management.","PeriodicalId":11022,"journal":{"name":"Current Opinion in Psychiatry","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148905325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integrating peer support in the treatment of personality disorders: current evidence and dimensional perspective. 在人格障碍治疗中整合同伴支持：当前证据和维度视角。

IF 5.9 2区医学

Current Opinion in Psychiatry Pub Date : 2026-08-27 DOI: 10.1097/YCO.0000000000001120

Martin Blay, Carla Sharp, Nicholas J S Day

{"title":"Integrating peer support in the treatment of personality disorders: current evidence and dimensional perspective.","authors":"Martin Blay, Carla Sharp, Nicholas J S Day","doi":"10.1097/YCO.0000000000001120","DOIUrl":"https://doi.org/10.1097/YCO.0000000000001120","url":null,"abstract":"Purpose of review: Peer support interventions have emerged as a promising adjunct to the treatment of personality disorders, particularly borderline personality disorder (BPD). This review summarizes the rapidly expanding literature on peer support in personality disorders and proposes a dimensional reinterpretation of its potential mechanisms of action through dimensional models of personality functioning.Recent findings: Recent literature supports the feasibility, acceptability, and preliminary efficacy of peer support interventions in BPD. Benefits have been reported across recovery-related outcomes, including validation, hope, empowerment, social connectedness, emotion regulation, and, more recently, BPD symptoms and personality functioning. Despite these advances, evidence remains almost exclusively restricted to BPD. Reinterpreting literature through a dimensional framework suggests that the therapeutic processes most consistently reported may influence core domains of personality functioning, including identity, self-direction, empathy, and intimacy.Summary: Peer support is a feasible and promising complement to evidence-based treatments for personality disorders, provided that adequate training, supervision, role clarity, and organizational support are ensured. A dimensional perspective offers a coherent framework for understanding its potential transdiagnostic relevance by targeting impairments in personality functioning rather than diagnosis-specific symptoms. Future research should extend investigations beyond BPD and clarify the mechanisms through which peer support contributes to recovery.","PeriodicalId":11022,"journal":{"name":"Current Opinion in Psychiatry","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148905346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Arterial spin labeling-derived cerebral blood flow as a translational biomarker and candidate surrogate endpoint for cognitive impairment. 动脉自旋标记衍生的脑血流作为认知障碍的翻译生物标志物和候选替代终点。

IF 5.9 2区医学

Current Opinion in Psychiatry Pub Date : 2026-08-27 DOI: 10.1097/YCO.0000000000001112

Satoshi Hosoki, Perminder S Sachdev, Masafumi Ihara

{"title":"Arterial spin labeling-derived cerebral blood flow as a translational biomarker and candidate surrogate endpoint for cognitive impairment.","authors":"Satoshi Hosoki, Perminder S Sachdev, Masafumi Ihara","doi":"10.1097/YCO.0000000000001112","DOIUrl":"https://doi.org/10.1097/YCO.0000000000001112","url":null,"abstract":"Purpose of review: Arterial spin labeling (ASL) MRI noninvasively quantifies cerebral blood flow (CBF), but its role as a mechanistic biomarker and surrogate endpoint in trials of cognitive impairment remains undefined. This review evaluates evidence linking regional CBF to cognition across Alzheimer's disease, mild cognitive impairment (MCI), and cerebral small vessel disease (SVD), with particular emphasis on CADASIL as a mechanistically informative model.Recent findings: Multipostlabeling-delay ASL, spatial coefficient of variation metrics, and harmonized processing pipelines have improved reproducibility. Cross-sectional and longitudinal studies consistently link reduced CBF to cognitive impairment, with baseline CBF predicting cognitive decline, MCI-to-Alzheimer's disease conversion, white matter hyperintensity progression, and vascular events. In CADASIL, CBF is independently associated with cognitive performance and predicts subcortical hyperintensity progression over 2 years. Interventional data from SPRINT MIND, PRESERVE, and pilot lecanemab studies indicate that ASL-CBF is responsive to therapy.Summary: Within the FDA-NIH BEST framework, ASL-CBF appears to meet several criteria consistent with a reasonably likely surrogate endpoint, capturing upstream, potentially reversible hemodynamic dysfunction beyond established structural markers. CADASIL provides an optimal context for qualifications. Larger clinical trials linking treatment-induced CBF changes to clinical benefit, further protocol harmonization, and regulatory engagement are needed to translate ASL-CBF into a validated trial endpoint.","PeriodicalId":11022,"journal":{"name":"Current Opinion in Psychiatry","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148905320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nonsuicidal self-injury and eating disorders. 非自杀性自残和饮食失调。

IF 5.9 2区医学

Current Opinion in Psychiatry Pub Date : 2026-08-27 DOI: 10.1097/YCO.0000000000001114

Sónia Gonçalves, Paulo P P Machado

{"title":"Nonsuicidal self-injury and eating disorders.","authors":"Sónia Gonçalves, Paulo P P Machado","doi":"10.1097/YCO.0000000000001114","DOIUrl":"https://doi.org/10.1097/YCO.0000000000001114","url":null,"abstract":"Purpose of review: Eating disorders (EDs) are characterized by a significant prevalence of nonsuicidal self-injury (NSSI) compared to healthy and psychiatric controls. This frequent co-occurrence has led researchers to investigate the common mechanisms driving this comorbidity. Understanding these factors is particularly urgent as the presence of NSSI is associated with diminished recovery in ED patients and increased risk for morbidity and mortality. This paper aims to synthesize the current understanding of the intersection between NSSI and ED.Recent findings: NSSI and EDs share common psychological functions, supporting a transdiagnostic approach. This overlapping, multidetermined nature may explain their frequent co-occurrence and why individuals often rely on them interchangeably. Emotion regulation, sensation seeking, and self-punishment might motivate both behaviours. This is crucial for clinical practice; targeting overlapping functions can mitigate both behaviours and disrupt replacement cycles.Summary: NSSI and ED are conceptualized as distinct behaviours on the self-harm spectrum. Their co-occurrence and body-centred focus have prompted significant research into the underlying factors that maintain both conditions. Effectively addressing NSSI and EDs requires looking past the behaviours to evaluate their functions alongside key risk factors. Recognizing the distinct functions of NSSI and ED behaviours can guide treatment decisions and improve outcomes.","PeriodicalId":11022,"journal":{"name":"Current Opinion in Psychiatry","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148975649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A review of contemporary research on eating disorders in the Ukrainian context. 在乌克兰背景下对饮食失调的当代研究综述。

IF 5.9 2区医学

Current Opinion in Psychiatry Pub Date : 2026-07-23 DOI: 10.1097/YCO.0000000000001111

Maryna Fatieieva, Olha Lazarenko

引用次数: 0

Risk and protective factors in addictive behaviors: Integrating artificial intelligence and traditional analytical methods to assess social and psychological determinants. 成瘾行为的风险和保护因素：整合人工智能和传统分析方法来评估社会和心理决定因素。

IF 5.9 2区医学

Current Opinion in Psychiatry Pub Date : 2026-07-01 Epub Date: 2026-04-30 DOI: 10.1097/YCO.0000000000001091

Germano Vera Cruz, Clarice Da Rosa, Yasser Khazaal

{"title":"Risk and protective factors in addictive behaviors: Integrating artificial intelligence and traditional analytical methods to assess social and psychological determinants.","authors":"Germano Vera Cruz, Clarice Da Rosa, Yasser Khazaal","doi":"10.1097/YCO.0000000000001091","DOIUrl":"10.1097/YCO.0000000000001091","url":null,"abstract":"Purpose of review: Addictive behaviors, including both substance use disorders and behavioral addictions, arise from complex interactions among biological, psychological, social, and environmental factors including digital ones. This review focuses on the assessment of social and psychological risk and protective factors, highlighting how artificial intelligence and machine learning approaches complement conventional qualitative and quantitative methodologies. The aim is to clarify how these tools can enhance understanding, prediction, and prevention of addictive behaviors.Recent findings: Recent research identifies impulsivity, emotion dysregulation, peer norms, and family functioning as central psychosocial risk factors for addictive behaviors. Protective factors - such as self-efficacy, social support, and family cohesion - moderate these risks. Conventional analyses provide foundational evidence, while ML methods (predictive machine learning, explainable artificial intelligence, reinforcement learning) now enable integration of multimodal data, detection of nonlinear patterns, and identification of latent psychosocial profiles. Emerging studies demonstrate potential for early-warning prediction and personalized intervention design.Summary: AI/ML offers unprecedented opportunities to advance addiction science by handling high-dimensional psychosocial and behavioral data. Yet, ethical, interpretative, and causal challenges persist. The most promising path forward lies in synergizing theory-driven analytics with data-driven AI approaches to achieve more precise and contextually grounded prevention and intervention strategies for addictive behaviors.","PeriodicalId":11022,"journal":{"name":"Current Opinion in Psychiatry","volume":" ","pages":"294-307"},"PeriodicalIF":5.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147765095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0