Current opinion in pediatrics最新文献

Editorial introductions.

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2025-04-01 Epub Date: 2025-03-06 DOI: 10.1097/MOP.0000000000001447

引用次数: 0

HPV vaccine hesitancy in the United States.

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2025-04-01 Epub Date: 2025-01-22 DOI: 10.1097/MOP.0000000000001441

Riya Joshi, Alexandra Kilinsky

{"title":"HPV vaccine hesitancy in the United States.","authors":"Riya Joshi, Alexandra Kilinsky","doi":"10.1097/MOP.0000000000001441","DOIUrl":"10.1097/MOP.0000000000001441","url":null,"abstract":"Purpose of review: Human papillomavirus (HPV) is the most common STI and accounts for roughly 37 000 HPV-associated cancers annually in the United States. Despite documented safety and effectiveness of the HPV vaccine, vaccination rates should be higher. We summarize literature surrounding vaccine hesitancy, a main reason for suboptimal vaccine coverage. We aim to describe the complex factors that lead to hesitancy in order to support improvement of vaccination rates in our communities.Recent findings: Studies document sustained immunogenicity and effectiveness 10 years post HPV vaccination. Vaccine coverage was rising until 2022, when initiation declined. Primary reasons for hesitancy are: perceived lack of provider recommendation, a lack of parental knowledge and necessity especially if an adolescent is not sexually active, and safety concerns. The COVID-19 pandemic challenged access to care and exacerbated vaccine-related discourse. Studies of hesitant adopters reveal that social processes, including conversations with community members, have a substantial impact on decisions to vaccinate.Summary: We highlight recent literature behind parental hesitancy toward the HPV vaccine, focusing on concerns about its necessity and safety, exacerbated by medical mistrust and misinformation. We summarize findings of successful educational outreach and community-based interventions to improve vaccination rates in the postpandemic social media era.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":" ","pages":"198-204"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reimagining apnea monitoring in the neonatal ICU. 新生儿ICU呼吸暂停监测的重新构想。

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2025-04-01 Epub Date: 2024-12-11 DOI: 10.1097/MOP.0000000000001432

Emily Jeanne, Ruben Alvaro, Wissam Shalish

{"title":"Reimagining apnea monitoring in the neonatal ICU.","authors":"Emily Jeanne, Ruben Alvaro, Wissam Shalish","doi":"10.1097/MOP.0000000000001432","DOIUrl":"10.1097/MOP.0000000000001432","url":null,"abstract":"Purpose of review: This review outlines the prevalence and complications of apneas and intermittent hypoxemic events in preterm infants, examines current monitoring limitations in neonatal ICUs (NICUs), and explores emerging technologies addressing these challenges.Recent findings: New evidence from the Prematurity-Related Ventilatory Control (Pre-Vent) study, which analyzed cardiorespiratory data from 717 extremely preterm infants, exposes the varying frequency, duration, and severity of apneas, intermittent hypoxemia, bradycardias, and periodic breathing during hospitalization, and highlights the negative impact of intermittent hypoxemia on pulmonary outcomes at discharge. Although traditional monitoring methods cannot differentiate between apnea types and quantify their burden, recent advancements in sensor technologies and data integration hold promise for improving real-time detection and evaluation of apneas in the NICU. Notably, small wearable mechano-acoustic sensors could improve apnea monitoring through continuous detection of airflow and respiratory efforts. Additionally, integrating bedside physiological data with modalities such as near-infrared spectroscopy, diaphragmatic activity, and electrical impedance tomography could help predict adverse outcomes by monitoring regional oxygen saturation and lung function in relation to apneas.Summary: Enhancing our understanding of neonatal apneas and overcoming the current limitations in apnea monitoring through advanced sensor technologies and data integration could lead to more personalized management and improved outcomes for preterm infants.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":" ","pages":"173-181"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utilizing preterm infant body composition assessments to guide neonatal nutrition. 利用早产儿身体成分评估指导新生儿营养。

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2025-04-01 Epub Date: 2025-01-02 DOI: 10.1097/MOP.0000000000001434

Catherine O Buck

{"title":"Utilizing preterm infant body composition assessments to guide neonatal nutrition.","authors":"Catherine O Buck","doi":"10.1097/MOP.0000000000001434","DOIUrl":"10.1097/MOP.0000000000001434","url":null,"abstract":"Purpose of review: The use of body composition to assess the quality of infant growth may add valuable information to pediatric clinical care. Preterm infants have differences in their fat and muscle mass development compared with infants born at term, which may be related to their early nutritional exposures. This review focuses on recent studies examining early nutrition in preterm infants and related body composition outcomes in the newborn period and beyond.Recent findings: Overall, the evidence shows that early nutrient delivery in parenteral nutrition and through formula supplementation or human milk fortification is associated with increased fat-free mass or lean mass in early life. However, future research is needed to fully understand the link between these body composition changes and longitudinal outcomes in preterm infants.Summary: Inclusion of body composition assessments in preterm infant nutrition research is critical to understand the factors associated with differences in adiposity and lean mass development in preterm infants. Medical fragility in preterm infants limits the routine use of body composition assessment tools which are currently validated, and additional studies are needed to thoroughly assess other methods which may be more feasible to integrate into bedside routine.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":" ","pages":"191-197"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reversal of Roe v. Wade and implications of legal restrictions for neonatal care.

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2025-04-01 Epub Date: 2025-02-07 DOI: 10.1097/MOP.0000000000001445

Christine E Bishop, Maya Manian

{"title":"Reversal of Roe v. Wade and implications of legal restrictions for neonatal care.","authors":"Christine E Bishop, Maya Manian","doi":"10.1097/MOP.0000000000001445","DOIUrl":"10.1097/MOP.0000000000001445","url":null,"abstract":"Purpose of review: This review examines the implications of the 2022 Dobbs v. Jackson Women's Health Organization decision on neonatal care and explores how legal restrictions on abortion are influencing medical practices for neonates and the broader healthcare landscape for neonates.Recent findings: The Dobbs decision has led to increased uncertainty and challenges in both maternal and neonatal healthcare. Restrictive abortion laws are associated with higher infant mortality rates, increased health disparity, and increased care provider ethical dilemmas and moral distress due to legal uncertainty surrounding the care of infants. However, current changes in federal and state law regarding abortion do not change the previously established standard of care for neonates. Other federal legal statutes potentially addressing the care of neonates have existed for over 20 years and have had minimal effect on the practice of neonatology, because there is no record of federal enforcement actions or federal case law to clarify how the law should be interpreted.Summary: While restrictive abortion laws primarily affect women and pregnant people's health care, indirect effects on neonatal care are becoming more common. There are other laws and policies with greater potential to regulate care for infants at the federal and state level. Professional medical standards remain the guiding framework in neonatal care. Clinicians can mitigate legal concerns through knowledge and advocacy.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":" ","pages":"165-172"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synchronicity of climate change and outbreaks of infectious diseases in children.

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2025-04-01 Epub Date: 2025-03-06 DOI: 10.1097/MOP.0000000000001443

Elijah Paintsil

引用次数: 0

Long-term impact of early identification of cerebral palsy. 早期识别脑瘫的长期影响。

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2025-04-01 Epub Date: 2025-01-10 DOI: 10.1097/MOP.0000000000001439

Ana-Marie Rojas

{"title":"Long-term impact of early identification of cerebral palsy.","authors":"Ana-Marie Rojas","doi":"10.1097/MOP.0000000000001439","DOIUrl":"10.1097/MOP.0000000000001439","url":null,"abstract":"Purpose of review: Early identification of cerebral palsy (CP), as in all neurologic conditions, has a profound impact on the ability to initiate interventions, support the education and empowerment of parents, ameliorate the effect of the conditions, and importantly identifies cohorts for neuroprotection or repair to address the primary injury. CP is a life span condition. Rapid initiation of services, support and anticipatory guidance is essential to maximize functional outcomes, prevent or manage complications and improve quality of life.Recent findings: CP diagnosis should not be delayed. Early imaging as well as motor and neurologic evaluation can aid in early detection of CP before age 5 months. Early therapeutic intervention can influence function and assist in prevention of complications that can impact abilities. There is important ongoing research with efforts to prevent CP or alter the phenotype of the condition.Summary: Literature review provides evidence to change in standard of care in diagnosing CP. There are published guidelines on how to pursue the diagnosis during early infancy. Early identification results in early intervention with the purpose of enhancing functional skill development, prevention of complications, and establishing parental support. Early identification provides an optimistic view and opportunity to intervene immediately in hopes to have an impact in the functional outcome and improving quality of life.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":" ","pages":"205-210"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The challenge of antimicrobial resistance in the Asia-Pacific: a pediatric perspective.

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2025-04-01 Epub Date: 2025-02-04 DOI: 10.1097/MOP.0000000000001437

Nguyen Xuan Huong, Michelle Harrison, Erena Kasahara, Ben Marais, Nina Dwi Putri, Phoebe Cm Williams

{"title":"The challenge of antimicrobial resistance in the Asia-Pacific: a pediatric perspective.","authors":"Nguyen Xuan Huong, Michelle Harrison, Erena Kasahara, Ben Marais, Nina Dwi Putri, Phoebe Cm Williams","doi":"10.1097/MOP.0000000000001437","DOIUrl":"10.1097/MOP.0000000000001437","url":null,"abstract":"Purpose of review: The densely populated Asia Pacific region is home to 600 million children, and suffers from a significant burden of morbidity and mortality due to infections associated with antimicrobial resistance (AMR). We aimed to identify the drivers, challenges and potential opportunities to alter the burden of AMR within the region.Recent findings: Despite the high AMR burden borne by the Asia Pacific region, there are limited (and geographically imbalanced) published data to delineate the contemporary epidemiology of serious multidrug-resistant bacterial infections in children. Furthermore, the region is impacted by overcrowded and poorly resourced healthcare facilities, insufficient microbiological resources, and widespread community and environmental antibiotic use leading to limited efficacy for frequently prescribed antibiotics. Vaccine coverage is also inadequate and inequitable, further driving the burden of infectious disease (and antibiotic overuse) in children.Summary of implications: There are many challenges in implementing antimicrobial stewardship and infection prevention and control programs to reduce the excessive AMR disease burden in children across the Asia Pacific region, yet locally-driven strategies have successfully reduced antibiotic overuse in some settings, and should be replicated. Reducing the AMR disease burden will require improved healthcare resourcing, including better access to microbiological diagnosis, and multidisciplinary approaches to enhance infection prevention and antibiotic prescribing.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":" ","pages":"116-123"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transgression of planetary boundaries and the effects on child health through an infectious diseases lens.

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2025-04-01 Epub Date: 2025-01-29 DOI: 10.1097/MOP.0000000000001442

Mikaela Coleman, Palwasha Y Khan, Lauren Linde, Phoebe C M Williams, Ben J Marais

{"title":"Transgression of planetary boundaries and the effects on child health through an infectious diseases lens.","authors":"Mikaela Coleman, Palwasha Y Khan, Lauren Linde, Phoebe C M Williams, Ben J Marais","doi":"10.1097/MOP.0000000000001442","DOIUrl":"10.1097/MOP.0000000000001442","url":null,"abstract":"Purpose of review: Life on earth, as we know it, is changing. The likelihood of more frequent pandemics and disease outbreaks is something that current global healthcare infrastructure is ill equipped to navigate. Human activity is forcing our planet into a new geologic epoch, the Anthropocene, which is typified by increased uncertainty resulting from human disruption of earth's life-giving ecosystems. Plagues and pandemics have always been unfortunate partners to periods of disruption, as they will be again if the frequency and severity of climate and conflict-mediated disasters increase in coming years. If we continue to exceed and degrade the planetary boundaries that protect human health, our children and their children will reap the consequences.Recent findings: Scientists have defined nine 'safe operating' planetary boundaries for life in all its glorious diversity to thrive on planet earth. Recent evidence suggests that six of these nine boundaries have already been transgressed, but the potential implications for these transgressions upon child health is not well articulated. We highlight how contravention of these boundaries will impact infectious disease risk and humans' ability to survive and thrive. We reflect specifically on how paediatricians are called upon to speak up for the most vulnerable members of our species, young children and as yet unborn future generations.Summary: Post COVID-19 initiatives to improve pandemic preparedness and response are certainly warranted, but pandemic prevention should include committed efforts not to exceed safe planetary boundaries. Willingly exceeding these boundaries has deep moral consequences that are poorly articulated by current ethical frameworks. Paediatricians are best placed to develop and champion the neglected 'third dimension' of medical ethics, recognizing the moral imperative to protect the long-term best interests of children and future generations.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":" ","pages":"124-136"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Overview of mucosal immunity and respiratory infections in children: a focus on Africa. 儿童粘膜免疫和呼吸道感染概述：聚焦非洲。

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2025-04-01 Epub Date: 2025-02-05 DOI: 10.1097/MOP.0000000000001438

Richard K Mwape, Mish-Al Barday, Marieke M van der Zalm, Lilly M Verhagen

{"title":"Overview of mucosal immunity and respiratory infections in children: a focus on Africa.","authors":"Richard K Mwape, Mish-Al Barday, Marieke M van der Zalm, Lilly M Verhagen","doi":"10.1097/MOP.0000000000001438","DOIUrl":"10.1097/MOP.0000000000001438","url":null,"abstract":"Purpose of review: Given the substantial burden of respiratory tract infections (RTIs) on global paediatric health, enhancing our understanding of mucosal immunity can help us advance mucosal biomarkers for diagnosis, prognosis and possible interventions in order to improve health outcomes. This review highlights the critical role of mucosal immunity in paediatric RTIs and recent advances in mucosal interventions, which offer promising strategies to improve outcomes.Recent findings: The significant burden of paediatric RTIs and growing interest in mucosal immunity advanced our understanding of the role of the respiratory mucosal immune system in protective immunity against RTIs. Studies show that sub-Saharan Africa is disproportionately affected by paediatric RTIs with poverty-associated factors such as human immunodeficiency virus (HIV) and malnutrition as risk factors. Emerging evidence highlights the important role of the respiratory microbiome and mucosal innate and adaptive immune responses in protective immunity against RTIs.Summary: The growing interest in mucosal immunity in RTIs has not only advanced our understanding of the overall immune responses in RTIs but also created opportunities to improve RTI care through translation of knowledge from these studies into diagnostics, therapeutics, and vaccines.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":" ","pages":"137-144"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0