Current Nutrition Reports最新文献

{"title":"Cancer Risk and Mortality Following Substitution of Animal Foods with Plant Foods: A Systematic Review.","authors":"Mariana Del Carmen Fernández-Fígares Jiménez, Maximilian Andreas Storz","doi":"10.1007/s13668-025-00688-3","DOIUrl":"10.1007/s13668-025-00688-3","url":null,"abstract":"<p><strong>Purpose of the review: </strong>This systematic review aims to evaluate the evidence on replacing animal foods (eggs, red meat, processed meat, poultry, fish, and dairy products) with plant foods (fruits, vegetables, nuts, whole grains, soy, and non-soy legumes) regarding cancer risk, cancer mortality, and all-cause mortality.</p><p><strong>Recent findings: </strong>A systematic search was done using PubMed and Web of Science, adhering to the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analysis. Randomized controlled trials and cohort studies that substituted animal foods or animal protein with plant foods or plant protein were considered. The ROBINS-E tool was used to assess the risk of bias. A total of 17 articles were included, thereof 14 cohort studies, one case-cohort study, and two pooled analyses of cohort studies. Replacing animal foods or animal protein with plant foods or plant protein was associated with a reduced cancer risk in six studies (two studies on colorectal cancer, one on rectal cancer, and three on breast cancer), whereas four studies found no associations (one each for liver, bladder, colon and total cancer). The substitution of animal foods or animal protein with plant foods or plant protein was associated with a lower risk of cancer mortality and total mortality in three and five studies, respectively. Meta-analysis was not conducted due to the high heterogeneity of the studies. Substituting animal foods with plant foods may contribute to reducing the risk of breast and colorectal cancer, cancer mortality, and total mortality. Future studies should assess the effect of this substitution on other cancer types.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"99"},"PeriodicalIF":5.5,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144798458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanotechnology-Based Plant Antioxidants: A Current Literature Review on Bioavailability and Oxidative Stress.","authors":"Gül Eda Kılınç, Yasemin Açar Kuru","doi":"10.1007/s13668-025-00689-2","DOIUrl":"https://doi.org/10.1007/s13668-025-00689-2","url":null,"abstract":"","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"98"},"PeriodicalIF":5.5,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144788495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ergogenic Aid by Cordyceps: Does It Work??","authors":"Luthfia Dewi, Chutimon Khemtong","doi":"10.1007/s13668-025-00690-9","DOIUrl":"https://doi.org/10.1007/s13668-025-00690-9","url":null,"abstract":"<p><strong>Purpose of review: </strong>Supplements for exercise have gained significant attention among athletes and sports practitioners. Herbs with high bioactive content are commonly used to enhance exercise performance. Among these, Cordyceps spp., a traditional herb from China, is recognized for its pharmacological properties, including immunomodulatory, anti-inflammatory, and anti-fibrotic effects observed in vitro. As an immunomodulatory agent, Cordyceps has been shown to successfully stimulate cytokine synthesis in human peripheral blood. Given that inflammation is a natural part of the aerobic exercise response, We aim in this review to summarize the effects of Cordyceps on aerobic performance and fitness in human studies.</p><p><strong>Recent findings: </strong>Most studies involved active, young participants. Long-term supplementation with Cordyceps, ranging from 2 to 16 weeks, has demonstrated improvements in aerobic performance in a dose-dependent manner, as evidenced by an increase in time to exhaustion. However, the effects on aerobic fitness remain inconsistent. Furthermore, the ergogenic potential of Cordyceps in aging and sedentary populations requires further investigation due to the limited number of studies available. It also appears that Cordyceps supplementation may have a greater impact on aerobic performance and fitness when combined with other herbs and exercise training. Cordyceps supplementation shows potential as an ergogenic aid for exercise. Further research is needed to explore its effects at the cellular level in human studies.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"97"},"PeriodicalIF":5.5,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144788494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trans Fatty Acids and Chronic Metabolic Diseases: Molecular Mechanisms and Public Health Strategies for Risk Mitigation.","authors":"Nageena Qayyum, Ya Wang, Tingyi Mo, Zhixin Li, Shan Wang, Ruijie Liu, Bingquan Mo, Honghui Guo","doi":"10.1007/s13668-025-00683-8","DOIUrl":"https://doi.org/10.1007/s13668-025-00683-8","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review provides a comprehensive analysis of trans fatty acids (TFAs) and their impact on human health, examining the molecular mechanisms underlying TFA-induced pathogenesis of chronic diseases. We combine current evidence on TFA metabolism, cellular effects, and associated health outcomes to inform public health strategies.</p><p><strong>Recent findings: </strong>TFAs are mainly derived from two sources: industrial processes and natural biohydrogenation. Following dietary intake, TFAs are absorbed in the gastrointestinal tract and enter systemic circulation. Recent epidemiological and experimental evidence has shown that TFAs disrupt lipid metabolism, elevate oxidative stress, and activate inflammatory signaling pathways, including NF-κB. Additionally, TFAs induce endoplasmic reticulum stress and impair autophagy, contributing to insulin resistance, hepatic steatosis, and adipose tissue dysfunction. These processes impair systemic metabolic dysfunction. TFAs exert multiple adverse effects on metabolic and cellular processes, supporting their role in the progression of chronic diseases. Understanding the mechanistic basis of TFA-induced dysfunction underscores the importance of reducing dietary intake through regulatory policies and public health interventions.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"96"},"PeriodicalIF":5.5,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144783672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Vitamins and their Interactions on Depression: A Review.","authors":"Neil Mistry, Logan T Cowan, Hani M Samawi, Amenah Qotineh, Kelly L Sullivan","doi":"10.1007/s13668-025-00686-5","DOIUrl":"10.1007/s13668-025-00686-5","url":null,"abstract":"<p><strong>Purpose of review: </strong>Depression is highly prevalent in the United States. Literature has investigated common demographic risk factors and pharmacological and non-pharmacological treatments. The effects of vitamins and their interactions on depression prevalence and symptoms has gained interest, especially in the context of a large representative sample. The review aims to evaluate the literature concerning individual vitamins and their association with depression.</p><p><strong>Recent findings: </strong>Several observational studies have been conducted to determine the effects of individual vitamins on depression. These studies have conflicting results regarding the impact and magnitude of vitamin effects, and previous studies evaluating the effect of vitamin interactions on depression have limited generalizability. Despite pharmacologic and biological rationale supporting the potential role of vitamins in combating depression, results of studies evaluating vitamin intake and depression in humans are inconsistent and limited. Further research is needed to assess the link between nutrition and depression in robust populations, particularly in groups at risk for or suffering from depression.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"95"},"PeriodicalIF":5.5,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144717714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aging-Related Obesity: Unveiling Mitochondrial and Metabolic Dysfunction.","authors":"Tongbing Qi, Kexin Zhang, Jingwen Zhang, Yujie Ma, Ningning Hou, Xiaodong Sun, Fang Han, Sufang Sheng, Chengxia Kan","doi":"10.1007/s13668-025-00685-6","DOIUrl":"https://doi.org/10.1007/s13668-025-00685-6","url":null,"abstract":"","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"94"},"PeriodicalIF":4.6,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144697844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intermittent Fasting for the Prevention of Cardiovascular Disease Risks: Systematic Review and Network Meta-Analysis.","authors":"Kelemu Tilahun Kibret, Anna Peeters, Teketo Kassaw Tegegne, Yonatan Moges Mesfin, Melanie Nichols","doi":"10.1007/s13668-025-00684-7","DOIUrl":"10.1007/s13668-025-00684-7","url":null,"abstract":"<p><strong>Context: </strong>While several studies have assessed the potential effect of intermittent fasting on reducing cardiovascular risks, the findings are inconclusive.</p><p><strong>Objective: </strong>To compare the relative effectiveness of intermittent fasting methods in reducing key cardiovascular risks.</p><p><strong>Methods: </strong>Studies were searched from Medline, Embase, Cochrane Library Central and Global Health to identify studies that enrolled adults (≥ 18 years) to intermittent fasting methods and reported effects on one of the six specified cardiovascular risk factors. We performed a random-effects network meta-analysis using a frequentist framework. Outcomes were reported as mean differences (MD) with their corresponding 95% confidence intervals (CI).</p><p><strong>Results: </strong>Fifty-six studies were included in the analysis. With high certainty of evidence, modified alternate-day fasting was found to be the most effective intervention compared to a usual diet in reducing body weight (MD= -5.18 kg; 95% CI: -7.04, -3.32), waist circumference (-3.55 cm; -5.66, -1.45), systolic blood pressure (-7.24 mmHg; -11.90, -2.58), diastolic blood pressure (-4.70 mmHg; -8.46, -0.95). With high certainty, time-restricted eating was the most effective intervention compared to usual diet in reducing fat-free mass (-0.82 kg; -1.46, -0.17), waist circumference (-3.00 cm; -4.50, -1.51), diastolic blood pressure (-3.24 mmHg; -4.69, -1.79) and fasting plasma glucose (-3.74 mg/dL; -6.01, -1.46).</p><p><strong>Conclusions: </strong>Modified alternate-day fasting, and time-restricted eating appear to be promising approaches for reducing most cardiovascular risk factors. These intermittent fasting methods may be considered as potential components of lifestyle interventions aimed at managing cardiovascular disease risk factors. However, further long-term randomised controlled trials comparing intermittent fasting methods are needed to confirm their efficacy and assess their safety over time.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"93"},"PeriodicalIF":5.5,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12289860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144697845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbiota-Gut-Brain Axis and Impaired Satiety in Individuals with Obesity: A Potentially Bidirectional Association.","authors":"Mariana de Moura E Dias, Madalena Geralda Cupertino Ribeiro, Ana Claudia Pelissari Kravchychyn, Helen Hermana Miranda Hermsdorff","doi":"10.1007/s13668-025-00682-9","DOIUrl":"https://doi.org/10.1007/s13668-025-00682-9","url":null,"abstract":"","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"92"},"PeriodicalIF":4.6,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence in Clinical Nutrition: Bridging Data Analytics and Nutritional Care.","authors":"Jithinraj Edakkanambeth Varayil, Suzette J Bielinski, Manpreet S Mundi, Sara L Bonnes, Bradley R Salonen, Ryan T Hurt","doi":"10.1007/s13668-025-00680-x","DOIUrl":"https://doi.org/10.1007/s13668-025-00680-x","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review explores how artificial intelligence can help advance clinical nutrition and address nutrition education and practice challenges. It highlights the role of AI, mainly through advanced clinical decision-making using generative AI, in supporting clinicians as they develop personalized nutrition interventions for individual patients. Furthermore, the review discusses how AI technologies are helping to close the knowledge gap in nutrition and delivering real-time, evidence-based insights to healthcare professionals.</p><p><strong>Recent findings: </strong>AI processes, such as machine learning and natural language processing, have shown promising results in predicting nutritional outcomes and complications, such as malnutrition and central line-associated bloodstream infections. Studies highlight the capability of AI to efficiently process large datasets, identify key risk factors, and provide real-time support to clinicians. Furthermore, AI can personalize educational content, making complex nutritional concepts more accessible. AI has demonstrated multiple potential use cases in nutrition. However, much work still needs to be done to evaluate its accuracy, accessibility and ethical considerations.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"91"},"PeriodicalIF":4.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Nutraceutical Interventions for Hypertension: A Comprehensive Review of Randomized Clinical Evidence.","authors":"Liu Yanru, Vaidehi Ulaganathan, Baskaran Gunasekaran, Tanima Bhattacharya","doi":"10.1007/s13668-025-00681-w","DOIUrl":"https://doi.org/10.1007/s13668-025-00681-w","url":null,"abstract":"","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"90"},"PeriodicalIF":4.6,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144539364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}