Current Nutrition Reports最新文献

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Nutritional Problems in Neurodevelopmental Disorders: A Narrative Review. 神经发育障碍的营养问题:叙述性回顾。
IF 8 3区 医学
Current Nutrition Reports Pub Date : 2026-09-04 DOI: 10.1007/s13668-026-00797-7
Merve Nur Sariyer Temelli̇, Hilal Hizli Güldemi̇r, Esra Kilinç, Dilara Karaahmetoğlu, Nazan Özöner
{"title":"Nutritional Problems in Neurodevelopmental Disorders: A Narrative Review.","authors":"Merve Nur Sariyer Temelli̇, Hilal Hizli Güldemi̇r, Esra Kilinç, Dilara Karaahmetoğlu, Nazan Özöner","doi":"10.1007/s13668-026-00797-7","DOIUrl":"10.1007/s13668-026-00797-7","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review aims to provide a synthesized overview of dietary patterns and nutrition-related problems in individuals with neurodevelopmental disorders. The review focuses on studies addressing eating behaviors, nutritional difficulties, and intervention approaches in individuals diagnosed with Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD), intellectual disability, and Down syndrome. Relevant studies were identified through systematic searches of PubMed, Scopus, and Web of Science for articles published after 2010. Selection criteria included peer-reviewed studies examining sensory, behavioral, physiological, and environmental factors affecting dietary patterns.</p><p><strong>Recent findings: </strong>The reviewed studies indicate that individuals with ASD frequently exhibit food selectivity and sensory sensitivities that limit dietary variety. In ADHD, impulsive eating behaviors and irregular dietary patterns are associated with an increased risk of obesity. Individuals with intellectual disabilities often experience poor diet quality, swallowing difficulties, and micronutrient deficiencies, frequently influenced by environmental and caregiver-related factors. In Down syndrome, both feeding difficulties and an elevated risk of obesity are observed, influenced by genetic and metabolic characteristics. Nutritional problems in neurodevelopmental disorders are multifactorial, involving biological, behavioral, sensory, cognitive, and environmental influences. These findings highlight the importance of early identification and the implementation of individualized, multidisciplinary intervention strategies, including active family involvement. Further research using more standardized and methodologically rigorous approaches is needed to strengthen the evidence base.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"15 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sustainable Plant-Based Diets in Children and Adolescents: Current Evidence on Metabolic Syndrome and Cardiometabolic Health. 儿童和青少年可持续植物性饮食:代谢综合征和心脏代谢健康的最新证据
IF 8 3区 医学
Current Nutrition Reports Pub Date : 2026-09-03 DOI: 10.1007/s13668-026-00796-8
Yasemin Açar Kuru, Eda Köksal
{"title":"Sustainable Plant-Based Diets in Children and Adolescents: Current Evidence on Metabolic Syndrome and Cardiometabolic Health.","authors":"Yasemin Açar Kuru, Eda Köksal","doi":"10.1007/s13668-026-00796-8","DOIUrl":"10.1007/s13668-026-00796-8","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review summarizes current evidence on the role of plant-based and sustainable dietary patterns in relation to metabolic syndrome (MetS) during childhood and adolescence and examines how sustainability-oriented nutrition indices can be used to assess both health and environmental outcomes in younger populations, highlighting their potential role in supporting long-term metabolic health.</p><p><strong>Recent findings: </strong>Childhood and adolescence are critical periods for establishing lifelong dietary behaviors and preventing metabolic and cardiovascular diseases. Well-planned plant-based diets, rich in fiber, antioxidants, and phytochemicals, are associated with improved glycemic control, lipid profiles, and body composition, thereby positively influencing key components of MetS. Beyond these metabolic benefits, plant-based diets are associated with lower environmental impacts, including reductions in greenhouse gas emissions and a decreased use of natural resources. Several dietary indices have been developed to evaluate these relationships in children and adolescents, including the Planetary Health Diet Index (PHDI and PHDI-C), the Mediterranean Diet Quality Index (KIDMED), the DASH diet index, and the Plant-Based Diet Index (PDI). However, most available studies are cross-sectional, and longitudinal or randomized controlled trials investigating causal associations between sustainable diets and metabolic health outcomes in youth remain limited. Current evidence suggests that plant-based, nutritionally adequate, and sustainable diets during childhood and adolescence may contribute to improved metabolic health, a lower risk of MetS, and healthy growth and development. Integrating sustainability concepts into nutrition policies, dietary guidelines, and educational programs may promote healthier dietary behaviors and increase awareness among children, adolescents, and their families. However, current evidence is largely based on cross-sectional studies, and well-designed longitudinal and intervention studies are needed to strengthen the evidence base and clarify causal relationships.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"15 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional Modulation of the Gut Microbiome-Metabolite Axis in Cardiovascular Disease: From Dietary Patterns to Cardiovascular Risk. 心血管疾病中肠道微生物代谢物轴的营养调节:从饮食模式到心血管风险
IF 8 3区 医学
Current Nutrition Reports Pub Date : 2026-09-02 DOI: 10.1007/s13668-026-00795-9
Mina Mohammadzadeh, Mehtap Ünlü Söğüt, Amin Fazlzadeh, Menşure Nur Çelik
{"title":"Nutritional Modulation of the Gut Microbiome-Metabolite Axis in Cardiovascular Disease: From Dietary Patterns to Cardiovascular Risk.","authors":"Mina Mohammadzadeh, Mehtap Ünlü Söğüt, Amin Fazlzadeh, Menşure Nur Çelik","doi":"10.1007/s13668-026-00795-9","DOIUrl":"10.1007/s13668-026-00795-9","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Purpose of review: &lt;/strong&gt;Cardiovascular disease (CVD) remains the leading cause of mortality worldwide, and dietary modification represents one of the most important modifiable strategies for its prevention and management. Increasing evidence indicates that the cardiovascular effects of diet extend beyond direct effects of nutrients and are partly mediated by interactions between dietary substrates, the gut microbiota, and host metabolism. This review critically evaluates the role of diet-microbiota interactions in CVD pathogenesis and provides an integrated, metabolite-centered perspective on how major dietary patterns influence gut microbial metabolism and cardiovascular health. Particular attention is given to trimethylamine N-oxide (TMAO), lipopolysaccharides (LPS), short-chain fatty acids (SCFAs), bile acids (BAs), phenylacetylglutamine (PAGln), indolepropionic acid (IPA), and hydrogen sulfide (H₂S).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Recent findings: &lt;/strong&gt;Dietary patterns substantially influence microbial composition, substrate availability, intestinal barrier integrity, and the production or transformation of microbiota-associated metabolites. Western-style, animal-based, and high-fat dietary patterns, may promote proteolytic and sulfidogenic fermentation, dysbiosis, impaired intestinal barrier function, and increased production or availability of potentially harmful metabolites. TMAO and PAGln have been associated with atherosclerosis, endothelial dysfunction, platelet activation, thrombosis, and other cardiometabolic outcomes, although their associations with cardiovascular risk may depend on dietary source, renal function, host metabolism, and individual microbial characteristics. LPS provides an important link between intestinal permeability, metabolic endotoxemia, inflammation, and vascular dysfunction. In contrast, fiber-rich and plant-based dietary patterns promote saccharolytic fermentation and SCFA production, support microbial diversity and intestinal barrier integrity, and may reduce endotoxemia and the production of potentially adverse microbial metabolites. Mediterranean dietary patterns, characterized by high consumption of plant foods, whole grains, fiber, olive oil, polyphenols, and fish together with lower intake of red and processed meat and refined sugars, appear to favor a more beneficial microbial and metabolic profile. BAs have more complex and context-dependent effects through microbial transformation and host signaling pathways, particularly FXR and TGR5. Emerging evidence also suggests potentially important cardiovascular roles for IPA and H₂S; however, their dietary regulation and clinical relevance remain less well established. The gut microbiota represents an important metabolic interface linking dietary patterns with cardiovascular physiology and disease. The available evidence suggests that dietary patterns rich in plant foods, fiber, unsaturated fats, polyphenols, and other bioactive components may support benef","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"15 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148879417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential of Non-Conventional Processing to Modulate the Technobiofunctionality of Legumes. 非常规加工对豆科植物技术生物功能调节的潜力。
IF 8 3区 医学
Current Nutrition Reports Pub Date : 2026-08-28 DOI: 10.1007/s13668-026-00794-w
Kiranbeer Kaur, Barinderjeet Singh Toor, Ankita Kataria
{"title":"Potential of Non-Conventional Processing to Modulate the Technobiofunctionality of Legumes.","authors":"Kiranbeer Kaur, Barinderjeet Singh Toor, Ankita Kataria","doi":"10.1007/s13668-026-00794-w","DOIUrl":"10.1007/s13668-026-00794-w","url":null,"abstract":"<p><strong>Purpose of review: </strong>The growing global demand for sustainable and nutritionally rich food sources has led to increased interest in legumes, owing to their high nutritional content and environmental benefits. Conventional processing techniques often pose constraints such as nutrient loss, flavour degradation, and energy inefficiency. Exploring and implementing non-conventional processing techniques may address these issues and open new opportunities for enhancing legume functionality.</p><p><strong>Recent findings: </strong>Several approaches for coupling conventional and non-conventional technologies have been explored to process legumes and achieve an optimal balance of enhanced nutritional and functional properties with reduced antinutritional components. The various categories of non-conventional techniques include thermal methods (microwave and ohmic heating), non-thermal methods (ultrasonication, high-pressure processing and pulsed electric field treatment), and emerging technologies (3D food printing, cold plasma processing and superheated steam processing). These techniques have been reviewed, with an emphasis on their principles and effects on compositional, antioxidative, and functional parameters when applied to various legumes. Non-conventional techniques, individually or in combination with conventional processes, exhibit significant potential to enhance the functionality of legumes. Their application can effectively improve the nutritional quality, functionality, and suitability of legumes for incorporation into various functional food formulations, thereby contributing to sustainable food innovation and global nutrition security.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"15 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148839413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A National Framework for Home Parenteral Nutrition in the United States: Accreditation, Reimbursement, Registry. 美国家庭肠外营养国家框架:认证、报销、登记。
IF 8 3区 医学
Current Nutrition Reports Pub Date : 2026-08-28 DOI: 10.1007/s13668-026-00793-x
Andrew B Schneider, Elizabeth Bruenderman, Keith Miller
{"title":"A National Framework for Home Parenteral Nutrition in the United States: Accreditation, Reimbursement, Registry.","authors":"Andrew B Schneider, Elizabeth Bruenderman, Keith Miller","doi":"10.1007/s13668-026-00793-x","DOIUrl":"10.1007/s13668-026-00793-x","url":null,"abstract":"<p><strong>Purpose of review: </strong>The United States delivers home parenteral nutrition (HPN) for chronic intestinal failure through a fragmented mix of hospitals, home-infusion companies, and individual clinicians, with no national accreditation pathway and no mandated standards for prescriber expertise or institutional capability. This review proposes a national framework for accountable, outcomes-driven HPN care and a phased path to its implementation.</p><p><strong>Recent findings: </strong>Claims-based analyses of approximately 24,000 U.S. adults on parenteral support show that most orders are written by clinicians managing very few patients over short intervals, with expertise concentrated in a small minority of providers and substantial travel burden in rural regions. A recently published international framework proposes principles for centralizing adult intestinal failure services but does not address implementation within the U.S. regulatory and payment architecture. Long-standing centralized systems in Denmark and the Czech Republic demonstrate what an organized system can achieve and what it can observe about its own performance. The fundamental problem is not that decentralized U.S. HPN care is demonstrably worse, but that the absence of national data makes the question unanswerable. There is no national registry, no standardized outcome reporting, and no national figure for infection, readmission, or weaning. We propose three pillars to centralize accountability rather than geography: tiered accreditation distinguishing Level I hubs from Level II regional spokes, with volume measured as network accountability; reimbursement reform funding longitudinal clinical management separately from supply; and a national registry with participation tied to payment.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"15 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148839447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultra-Processed Foods and Metabolic Dysfunction: Mechanisms, Clinical Implications, and Public Health Perspectives. Position Paper of the Italian Association of Dietetics and Clinical Nutrition (ADI). 超加工食品和代谢功能障碍:机制、临床意义和公共卫生观点。意大利营养和临床营养协会(ADI)的立场文件。
IF 8 3区 医学
Current Nutrition Reports Pub Date : 2026-08-26 DOI: 10.1007/s13668-026-00790-0
Giovanna Trinchese, Barbara Paolini, Fabiano Cimmino, Filippo Valoriani, Lucio Lucchin, Carmela Bagnato, Annarita Sabbatini, Massimiliano Petrelli, Pietro Losignore, Francesca Marino, Giulia Tavella, Odette Misa Sonia Hassan, Annalisa Maghetti, Maria Grazia Carbonelli, Sebastiano Banni, Luigi Barrea, Maria Pina Mollica
{"title":"Ultra-Processed Foods and Metabolic Dysfunction: Mechanisms, Clinical Implications, and Public Health Perspectives. Position Paper of the Italian Association of Dietetics and Clinical Nutrition (ADI).","authors":"Giovanna Trinchese, Barbara Paolini, Fabiano Cimmino, Filippo Valoriani, Lucio Lucchin, Carmela Bagnato, Annarita Sabbatini, Massimiliano Petrelli, Pietro Losignore, Francesca Marino, Giulia Tavella, Odette Misa Sonia Hassan, Annalisa Maghetti, Maria Grazia Carbonelli, Sebastiano Banni, Luigi Barrea, Maria Pina Mollica","doi":"10.1007/s13668-026-00790-0","DOIUrl":"10.1007/s13668-026-00790-0","url":null,"abstract":"<p><strong>Purpose of review: </strong>This position paper by the Italian Association of Dietetics and Clinical Nutrition (ADI) evaluates the impact of ultra-processed foods (UPFs) on metabolic health and chronic disease risk, with particular attention to the biological and behavioural mechanisms involved.</p><p><strong>Recent findings: </strong>High UPFs consumption has been associated with obesity, insulin resistance, cardiovascular disease, metabolic dysfunction-associated steatotic liver disease (MASLD), cancer, neuroinflammation, and immune dysregulation. Proposed mechanisms include gut microbiota alterations, increased intestinal permeability, mitochondrial dysfunction, oxidative stress, impaired metabolic flexibility, and chronic low-grade inflammation. The hyperpalatable nature of UPFs may also impair appetite regulation and promote overconsumption, especially among children and adolescents. Additional concerns involve food additives, processing-derived contaminants, and endocrine disruptors from packaging materials. Current evidence identifies UPFs as a major modifiable risk factor for non-communicable chronic diseases. Reducing UPFs exposure should therefore represent a public health priority, supported by preventive nutritional strategies, improved food classification systems, and targeted educational and regulatory interventions.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"15 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13518480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148826043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolic Changes of Perimenopause and Nutritional Advice. 围绝经期代谢变化及营养建议。
IF 8 3区 医学
Current Nutrition Reports Pub Date : 2026-08-17 DOI: 10.1007/s13668-026-00788-8
S L R Bonnes, H Nordhues, R Sood, D Kulick, A Muratore, E Bischof
{"title":"Metabolic Changes of Perimenopause and Nutritional Advice.","authors":"S L R Bonnes, H Nordhues, R Sood, D Kulick, A Muratore, E Bischof","doi":"10.1007/s13668-026-00788-8","DOIUrl":"https://doi.org/10.1007/s13668-026-00788-8","url":null,"abstract":"<p><strong>Purpose of review: </strong>Perimenopause is a period of hormonal volatility associated with clinically relevant changes in metabolism and cardiometabolic risk. In addition to vasomotor symptoms, sleep disruption, and changes in body composition, the transition from the late reproductive years to early postmenopause is characterized by physiologic alterations that may precede formal diagnostic thresholds for metabolic syndrome. However, screening and risk stratification are often anchored to postmenopausal benchmarks, potentially delaying identification of individuals at elevated risk.</p><p><strong>Recent findings: </strong>Accumulating evidence supports earlier attention to dynamic indices of cardiometabolic deterioration during perimenopause. Lifestyle interventions and, for selected individuals, menopausal hormone therapy may mitigate progression, although important uncertainties remain, including the long-term effectiveness of precision nutrition approaches and genotype-informed strategies. This narrative review summarizes physiologic changes across the menopausal transition and evaluates nutrition and lifestyle interventions that may attenuate adverse metabolic trajectories.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"15 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13481730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148789301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanistic Insights into Houttuynia cordata Thunb. as a Potential Therapeutic Strategy Targeting Metabolic Disorders in Preclinical Models. 鱼腥草(Houttuynia cordata Thunb)的机理研究。在临床前模型中作为针对代谢紊乱的潜在治疗策略。
IF 8 3区 医学
Current Nutrition Reports Pub Date : 2026-08-14 DOI: 10.1007/s13668-026-00791-z
Manashi Karmakar, Binita Chakraborty, Simanta Jyoti Chetia, Nasrin Haque, Punam Kumari, Ameena Ahmed, Pervej Alom Barbhuiya, Pratap Kalita, Kalyani Pathak, Manash Pratim Pathak
{"title":"Mechanistic Insights into Houttuynia cordata Thunb. as a Potential Therapeutic Strategy Targeting Metabolic Disorders in Preclinical Models.","authors":"Manashi Karmakar, Binita Chakraborty, Simanta Jyoti Chetia, Nasrin Haque, Punam Kumari, Ameena Ahmed, Pervej Alom Barbhuiya, Pratap Kalita, Kalyani Pathak, Manash Pratim Pathak","doi":"10.1007/s13668-026-00791-z","DOIUrl":"10.1007/s13668-026-00791-z","url":null,"abstract":"<p><strong>Background: </strong>Metabolic syndrome comprises insulin resistance, obesity, hypertension, and dyslipidaemia, increasing the risk of diabetes and cardiovascular diseases. It is a major contributor to global mortality. Approximately 28-31% of the global adult population is affected, with higher prevalence in women (~ 31%) than men (~ 25.7%). Metformin, pioglitazone, and vitamin E are examples of conventional medications that have demonstrated therapeutic advantages, while some patients may experience side effects. This has led to increasing interest in complementary natural compounds that are being studied for their potential efficacy and safety. Houttuynia cordata (H.C), an edible medicinal plant rich in bioactive compounds, has shown potential to regulate lipid metabolism, improve insulin sensitivity, and support hepatic function. This review therefore, focuses on the current preclinical evidence regarding the mechanistic roles of H.C and its bioactive compounds in ameliorating metabolic syndrome and related metabolic abnormalities.</p><p><strong>Main findings: </strong>H.C contains bioactive compounds such as α-pinene, myrcene, β-caryophyllene, limonene, and linalool, which exhibit therapeutic potential. Studies report its extracts (volatile and non-volatile), flavonoids, and phenolics demonstrate anti-hyperglycaemic effects, improve lipid profiles, reduce hepatic lipid accumulation via AMPK activation, and downregulate lipogenic genes. Although generally considered safe as an edible plant, some evidence suggests potential renal toxicity linked to aristolochic acid.</p><p><strong>Conclusion: </strong>H.C and its bioactive phytoconstituents have demonstrated promising potential in ameliorating metabolic syndrome in preclinical studies. However, the current evidence supporting the efficacy of H.C extracts in managing metabolic syndrome remains limited. Therefore, further investigations employing well-designed methodologies are essential. Comprehensive research and clinical evaluations are needed to elucidate the precise mechanisms of H.C, which may facilitate its development into an effective therapeutic strategy for the treatment of metabolic syndrome.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"15 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148759847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Sprouting in Gluten-Free Foods: Effects on Glycemic Response and Antioxidant Activity. 无麸质食品中发芽的作用:对血糖反应和抗氧化活性的影响。
IF 8 3区 医学
Current Nutrition Reports Pub Date : 2026-08-14 DOI: 10.1007/s13668-026-00792-y
Rabia Busra Isin, Mevlude Kizil
{"title":"The Role of Sprouting in Gluten-Free Foods: Effects on Glycemic Response and Antioxidant Activity.","authors":"Rabia Busra Isin, Mevlude Kizil","doi":"10.1007/s13668-026-00792-y","DOIUrl":"10.1007/s13668-026-00792-y","url":null,"abstract":"<p><strong>Purpose of review: </strong>Gluten-free (GF) products are frequently characterized by reduced nutritional and sensory quality, as well as a higher glycemic index (GI) compared to conventional products. These attributes may pose challenges for individuals who adhere to a lifelong gluten-free diet (GFD). Sprouting has emerged as a promising strategy to enhance the nutritional profile of GF foods. This review evaluates the impact of sprouting on glycemic response and antioxidant activity in GF foods, with a particular focus on the underlying mechanisms.</p><p><strong>Recent findings: </strong>Recent studies indicate that sprouting enhances antioxidant activity, primarily by increasing endogenous enzyme activity and releasing bound phenolic compounds. However, its effects on glycemic response remain inconsistent. Sprouting may increase starch digestibility through enhanced α-amylase activity, yet it can also promote the formation of resistant starch and increase dietary fiber content, potentially contributing to lower glycemic responses. These changes are influenced by processing conditions such as time and temperature, as well as by factors related to the food system, including matrix characteristics and seed properties. Sprouting represents a promising approach to improving the functional properties of GF foods, particularly by enhancing antioxidant activity. However, its impact on glycemic response is variable and largely determined by the specific food system and processing context. Current evidence emphasizes the importance of considering formulation and matrix interactions when assessing glycemic outcomes. Future research should focus on well-controlled human studies and standardized formulations to clarify the independent effects of sprouting and to support the development of low-glycemic, nutritionally improved GF products.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"15 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148766009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Healthy Diet for Healthy Minds: Insights from Recent Epidemiological Studies. 健康的饮食健康的头脑:从最近的流行病学研究的见解。
IF 8 3区 医学
Current Nutrition Reports Pub Date : 2026-08-10 DOI: 10.1007/s13668-026-00789-7
Suvisesh Pothuraju, Siddharth Narayanan, Sarah J Chen, Abid Hussain, Yaser Al-Salmay, Mary Eng, Jason M Vanatta, Sara L R Bonnes, Sunhee Park, Christopher M Jones
{"title":"Healthy Diet for Healthy Minds: Insights from Recent Epidemiological Studies.","authors":"Suvisesh Pothuraju, Siddharth Narayanan, Sarah J Chen, Abid Hussain, Yaser Al-Salmay, Mary Eng, Jason M Vanatta, Sara L R Bonnes, Sunhee Park, Christopher M Jones","doi":"10.1007/s13668-026-00789-7","DOIUrl":"10.1007/s13668-026-00789-7","url":null,"abstract":"<p><strong>Purpose of review: </strong>Age-related cognitive decline is a major public health challenge and has a significant impact on a country's economy and economic growth. Evidence suggests dietary patterns such as the Mediterranean Diet (MeDi), Dietary Approaches to Stop Hypertension (DASH), Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND), Alternative Health Eating Index (AHEI) and plant-based diets are associated with reduced cognitive decline and improved brain health. The main objective of this review is to summarize recent data and provide a literature-based evaluation of the effects of popular dietary patterns associated with cognitive health.</p><p><strong>Recent findings: </strong>An in-depth evaluation of the current literature suggests that adherence to healthy dietary patterns-including the MeDi, DASH, MIND, AHEI, and plant-based diets-can play an important role in preserving cognitive function and delaying cognitive aging. However, gaps remain in understanding the effects of long-term dietary adherence, specific food constituents, culturally diverse dietary practices, and the underlying molecular and neurophysiological mechanisms. These factors warrant further investigation to identify causal relationships between dietary patterns and beneficial effects on cognitive health. Literature-based evaluation offers a strong correlation between diet, nutrition, and age-related cognitive health. Despite these observations, studies affirm that new research incorporating well-powered longitudinal studies and culturally adaptable interventions are equally necessary. Furthermore, public health officials and global health entities should implement evidence-based and well-researched nutritional policies that are aimed at preserving cognitive health.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"15 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148700903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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