Current Nutrition Reports最新文献_第3页

Effects of Phytochemicals on Type 2 Diabetes via MicroRNAs. 植物化学物质通过微RNA对2型糖尿病的影响

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2024-09-01 Epub Date: 2024-05-28 DOI: 10.1007/s13668-024-00549-5

Dilek Sivri, Makbule Gezmen-Karadağ

{"title":"Effects of Phytochemicals on Type 2 Diabetes via MicroRNAs.","authors":"Dilek Sivri, Makbule Gezmen-Karadağ","doi":"10.1007/s13668-024-00549-5","DOIUrl":"10.1007/s13668-024-00549-5","url":null,"abstract":"Purpose of review: Type 2 diabetes, characterized by inadequate insulin secretion and resistance, is increasingly prevalent. To effectively manage type 2 diabetes, identifying new therapeutic targets is crucial. MicroRNAs, short noncoding RNA molecules, play a pivotal role in regulating β-cell function, insulin production, and resistance, and show promise as biomarkers for predicting type 2 diabetes onset. Phytochemicals, known for their antioxidant activities, may influence microRNA expression, potentially improving insulin sensitivity and mitigating associated complications. This review aims to explore the significance of microRNA in type 2 diabetes, their potential as biomarkers, and how certain phytochemicals may modulate microRNA expressions to reduce or prevent diabetes and its complications.Recent findings: Current research suggests that microRNAs show promise as novel therapeutic biomarkers for diagnosing type 2 diabetes and monitoring diabetic complications. Additionally, phytochemicals may regulate microRNAs to control type 2 diabetes, presenting a potential therapeutic strategy. The multifactorial effects of phytochemicals on type 2 diabetes and its complications through microRNAs warrant further research to elucidate their mechanisms. Comprehensive clinical trials are needed to assess the safety and efficacy of phytochemicals and their combinations. Given their ability to modulate microRNAs expression, incorporating phytochemical-rich foods into the diet may be beneficial.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11327184/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141157983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nourishing Physical Productivity and Performance On a Warming Planet - Challenges and Nutritional Strategies to Mitigate Exertional Heat Stress. 在日益变暖的地球上提高体力生产率和工作表现--减轻劳累性热应激的挑战和营养策略。

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2024-09-01 Epub Date: 2024-07-12 DOI: 10.1007/s13668-024-00554-8

Alan J McCubbin, Christopher G Irwin, Ricardo J S Costa

{"title":"Nourishing Physical Productivity and Performance On a Warming Planet - Challenges and Nutritional Strategies to Mitigate Exertional Heat Stress.","authors":"Alan J McCubbin, Christopher G Irwin, Ricardo J S Costa","doi":"10.1007/s13668-024-00554-8","DOIUrl":"10.1007/s13668-024-00554-8","url":null,"abstract":"PURPOSE OF REVIEW: Climate change is predicted to increase the frequency and severity of exposure to hot environments. This can impair health, physical performance, and productivity for active individuals in occupational and athletic settings. This review summarizes current knowledge and recent advancements in nutritional strategies to minimize the impact of exertional-heat stress (EHS). RECENT FINDINGS: Hydration strategies limiting body mass loss to < 3% during EHS are performance-beneficial in weight-supported activities, although evidence regarding smaller fluid deficits (< 2% body mass loss) and weight-dependent activities is less clear due to a lack of well-designed studies with adequate blinding. Sodium replacement requirements during EHS depends on both sweat losses and the extent of fluid replacement, with quantified sodium replacement only necessary once fluid replacement > 60-80% of losses. Ice ingestion lowers core temperature and may improve thermal comfort and performance outcomes when consumed before, but less so during activity. Prevention and management of gastrointestinal disturbances during EHS should focus on high carbohydrate but low FODMAP availability before and during exercise, frequent provision of carbohydrate and/or protein during exercise, adequate hydration, and body temperature regulation. Evidence for these approaches is lacking in occupational settings. Acute kidney injury is a potential concern resulting from inadequate fluid replacement during and post-EHS, and emerging evidence suggests that repeated exposures may increase the risk of developing chronic kidney disease. Nutritional strategies can help regulate hydration, body temperature, and gastrointestinal status during EHS. Doing so minimizes the impact of EHS on health and safety and optimizes productivity and performance outcomes on a warming planet.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11327203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141589848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cholesterol and Immune Microenvironment: Path Towards Tumorigenesis. 胆固醇与免疫微环境：通往肿瘤发生之路。

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2024-09-01 Epub Date: 2024-05-02 DOI: 10.1007/s13668-024-00542-y

Eslam E Saad, Rachel Michel, Mostafa A Borahay

{"title":"Cholesterol and Immune Microenvironment: Path Towards Tumorigenesis.","authors":"Eslam E Saad, Rachel Michel, Mostafa A Borahay","doi":"10.1007/s13668-024-00542-y","DOIUrl":"10.1007/s13668-024-00542-y","url":null,"abstract":"Purpose of review: Since obesity is a major risk factor for many different types of cancer, examining one of the most closely associated comorbidities, such as hypercholesterolemia, is crucial to understanding how obesity causes cancer. Hypercholesterolemia is usually associated with many cardiovascular complications such as hypertension, angina, and atherosclerosis. In addition, cholesterol may be a major factor in increasing cancer risk. Cancer patients who received statins, an anti-hypercholesteremic medicine, demonstrated improved prognosis possibly through its effect on tumor proliferation, apoptosis, and oxidative stress. Cholesterol could also aid in tumor progression through reprogramming tumor immunological architecture and mediators. This review focuses on the immunomodulatory role of cholesterol on cellular and molecular levels, which may explain its oncogenic driving activity. We look at how cholesterol modulates tumor immune cells like dendritic cells, T cells, Tregs, and neutrophils. Further, this study sheds light on the modification of the expression pattern of the common cancer-related immune mediators in the tumor immune microenvironment, such as programmed cell death 1 (PD-1), cytotoxic T lymphocyte antigen-4 (CTLA-4), transforming growth factor-beta (TGF-β), interleukin 12 (IL-12), IL-23, and forkhead box protein P3 (FOXP3).Recent findings: We highlight relevant literature demonstrating cholesterol's immunosuppressive role, leading to a worse cancer prognosis. This review invites further research regarding the pathobiological role of cholesterol in many obesity-related cancers such as uterine fibroids, post-menopausal breast, colorectal, endometrial, kidney, esophageal, pancreatic, liver, and gallbladder cancers. This review suggests that targeting cholesterol synthesis may be a fruitful approach to cancer targeting, in addition to traditional chemotherapeutics.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140854005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Managing Micronutrient Deficiencies in High-Risk Patients: No Small Feat! 管理高危患者的微量营养素缺乏症：非同小可！

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2024-09-01 Epub Date: 2024-07-03 DOI: 10.1007/s13668-024-00552-w

Ethan Steele, David Liu, Endashaw Omer

{"title":"Managing Micronutrient Deficiencies in High-Risk Patients: No Small Feat!","authors":"Ethan Steele, David Liu, Endashaw Omer","doi":"10.1007/s13668-024-00552-w","DOIUrl":"10.1007/s13668-024-00552-w","url":null,"abstract":"Purpose of review: Micronutrients are vital dietary components for growth and development. Adequate intake of vitamins and minerals through diet is crucial for proper biomolecular and cellular functioning. Many developed countries supplement foods and micronutrient deficiencies are less common. However, many disease states impair micronutrient absorption, metabolism, and excretion. Thus, early recognition of the signs and symptoms of micronutrient deficiencies is critical for providers to improve quality of life and prevent complications in high-risk patients. This article reviews the basic function of micronutrients, recognizes the symptoms of each micronutrient deficiency, provides natural sources of intake, and discusses the diagnosis and supplementation of each micronutrient. High risk patients based on disease state for each micronutrient is discussed. In addition, Bariatric patients are a specific group at high risk of micronutrient deficiency and their management and supplementation for treatment is also covered.Recent findings: Micronutrients play a vital role in antioxidant defense, especially in critically ill patients, due to an increase in oxidative stress. Early intervention with high-dose supplementation with vitamin C, vitamin E, zinc and selenium may have beneficial effects. Micronutrients deficiency remains an issue for patients in the developed world. Providers should recognize patients who are at high risk for micronutrients deficiencies and provide proper screening and prompt supplementation after diagnosis to prevent complications of micronutrient deficiencies.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141491195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Short-Chain Fatty Acids in Myocardial Ischemia-Reperfusion Injury. 短链脂肪酸在心肌缺血再灌注损伤中的作用

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2024-08-07 DOI: 10.1007/s13668-024-00564-6

Xunxun Wang, Yalan Dong, Renyin Huang, Fang Wang, Junke Xie, Hui Liu, Yan Wang, Yi Wang, Shanshan Luo, Desheng Hu

{"title":"The Role of Short-Chain Fatty Acids in Myocardial Ischemia-Reperfusion Injury.","authors":"Xunxun Wang, Yalan Dong, Renyin Huang, Fang Wang, Junke Xie, Hui Liu, Yan Wang, Yi Wang, Shanshan Luo, Desheng Hu","doi":"10.1007/s13668-024-00564-6","DOIUrl":"https://doi.org/10.1007/s13668-024-00564-6","url":null,"abstract":"Purpose of review: This study aims to review the effects of short-chain fatty acids (SCFAs) in regulating the myocardial ischemia-reperfusion injury (MIRI).Recent findings: Coronary heart disease (CHD) is a well-known leading cause of death and disability worldwide. Cardiac substrate metabolism plays the determinant role in assessing the severity of heart injury due to the abruptly shifted energy production during the MIRI. Fatty acids are the main energy fuels for the heart, which are classified into long-, medium- and short chain fatty acids by the length of carbon chain. SCFAs are the main metabolites derived from the anaerobic bacterial fermentation of fiber-rich diets, which are shown to play a protective role in cerebrovascular disease previously. Meanwhile, accumulating evidences suggest that SCFAs can also play a crucial role in cardiac energy metabolism. Results of various studies revealed the cardioprotective effects of SCFAs by displaying anti-inflammatory and anti-ferroptotic function, connecting gut-brain neural circuit and regulating the intestinal flora.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systematic Review of the Effects of Sparkling Water Consumption on Blood Pressure. 饮用气泡水对血压影响的系统综述。

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2024-07-30 DOI: 10.1007/s13668-024-00562-8

Héctor Santana-Ramos, Javier Batista

{"title":"Systematic Review of the Effects of Sparkling Water Consumption on Blood Pressure.","authors":"Héctor Santana-Ramos, Javier Batista","doi":"10.1007/s13668-024-00562-8","DOIUrl":"https://doi.org/10.1007/s13668-024-00562-8","url":null,"abstract":"Purpose of review: At present, almost all national health agencies and professional societies recommend reducing dietary sodium to lower blood pressure and prevent cardiovascular disease and stroke. The scientific community has questioned these recommendations multiple times. However, the institutions have clarified that the evidence supporting the reduction of sodium intake remains strong. This review is an examination of the literature on the impact of carbonated water consumption on the blood pressure of hypertensive patients RECENT FINDINGS: Current literature focuses on the act of ingestion and the immediate post-consumption periods, highlighting the significant role of the nervous system on blood pressure increase. This differs from earlier literature, which predominantly focused on hypotheses surrounding the nutritional components responsible for elevated blood pressure Research findings remains uncertainty regarding whether hypertensive patients should avoid the consumption of sparkling water. To contextualize these results, we discuss potential physiological mechanisms, recommendations from relevant organizations, and variations in methodologies and study designs. In conclusion, the question of whether hypertensive patients should steer clear of sparkling water remains unanswered.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141792178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Managing Cardiovascular Risk in Patients with Autoimmune Diseases: Insights from a Nutritional Perspective. 管理自身免疫性疾病患者的心血管风险：从营养角度看问题。

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2024-07-30 DOI: 10.1007/s13668-024-00563-7

Huimin Chen, Lu Liu, Yi Wang, Liqiong Hong, Jiahui Pan, Xiongkai Yu, Haijiang Dai

{"title":"Managing Cardiovascular Risk in Patients with Autoimmune Diseases: Insights from a Nutritional Perspective.","authors":"Huimin Chen, Lu Liu, Yi Wang, Liqiong Hong, Jiahui Pan, Xiongkai Yu, Haijiang Dai","doi":"10.1007/s13668-024-00563-7","DOIUrl":"https://doi.org/10.1007/s13668-024-00563-7","url":null,"abstract":"Purpose of review: Autoimmune diseases manifest as an immune system response directed against endogenous antigens, exerting a significant influence on a substantial portion of the population. Notably, a leading contributor to morbidity and mortality in this context is cardiovascular disease (CVD). Intriguingly, individuals with autoimmune disorders exhibit a heightened prevalence of CVD compared to the general population. The meticulous management of CV risk factors assumes paramount importance, given the current absence of a standardized solution to this perplexity. This review endeavors to address this challenge from a nutritional perspective.Recent findings: Emerging evidence suggests that inflammation, a common thread in autoimmune diseases, also plays a pivotal role in the pathogenesis of CVD. Nutritional interventions aimed at reducing inflammation have shown promise in mitigating cardiovascular risk. The integration of nutritional strategies into the management plans for patients with autoimmune diseases offers a holistic approach to reducing cardiovascular risk. While conventional pharmacological treatments remain foundational, the addition of targeted dietary interventions can provide a complementary pathway to improve cardiovascular outcomes.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141792177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Updated View of the Effect of Probiotic Supplement on Sports Performance: A Detailed Review. 益生菌补充剂对运动成绩影响的最新观点：详细综述。

IF 4.9 3区医学

Current Nutrition Reports Pub Date : 2024-06-01 Epub Date: 2024-03-12 DOI: 10.1007/s13668-024-00527-x

Miray Nur Aykut, Esma Nur Erdoğan, Menşure Nur Çelik, Murat Gürbüz

{"title":"An Updated View of the Effect of Probiotic Supplement on Sports Performance: A Detailed Review.","authors":"Miray Nur Aykut, Esma Nur Erdoğan, Menşure Nur Çelik, Murat Gürbüz","doi":"10.1007/s13668-024-00527-x","DOIUrl":"10.1007/s13668-024-00527-x","url":null,"abstract":"Purpose of review: Modulation of the host microbiota through probiotics has been shown to have beneficial effects on health in the growing body of research. Exercise increases the amount and diversity of beneficial microorganisms in the host microbiome. Although low- and moderate-intensity exercise has been shown to reduce physiological stress and improve immune function, high-intensity prolonged exercise can suppress immune function and reduce microbial diversity due to intestinal hypoperfusion. The effect of probiotic supplementation on sports performance is still being studied; however, questions remain regarding the mechanisms of action, strain used, and dose. In this review, the aim was to investigate the effects of probiotic supplements on exercise performance through modulation of gut microbiota and alleviation of GI symptoms, promotion of the immune system, bioavailability of nutrients, and aerobic metabolism.Recent findings: Probiotic supplementation may improve sports performance by reducing the adverse effects of prolonged high-intensity exercise. Although probiotics have been reported to have positive effects on sports performance, information about the microbiome and nutrition of athletes has not been considered in most current studies. This may have limited the evaluation of the effects of probiotic supplementation on sports performance.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11133216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140109589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimizing Intravenous Access for Long-Term Parenteral Nutrition. 优化长期肠外营养的静脉通路。

IF 4.9 3区医学

Current Nutrition Reports Pub Date : 2024-06-01 Epub Date: 2024-05-02 DOI: 10.1007/s13668-024-00534-y

Ryan T Hurt, Osman Mohamed Elfadil, Jithinraj Edakkanambeth Varayil, Sara L Bonnes, Bradley R Salonen, Manpreet S Mundi

{"title":"Optimizing Intravenous Access for Long-Term Parenteral Nutrition.","authors":"Ryan T Hurt, Osman Mohamed Elfadil, Jithinraj Edakkanambeth Varayil, Sara L Bonnes, Bradley R Salonen, Manpreet S Mundi","doi":"10.1007/s13668-024-00534-y","DOIUrl":"10.1007/s13668-024-00534-y","url":null,"abstract":"Purpose of review: Securing safe and effective intravenous (IV) access is of utmost importance for administering parenteral nutrition (PN). Sustaining this access can indeed pose challenges, especially when dealing with the risk of complications associated with long-term PN. This review emphasizes best practices to optimize intravenous access and reviews the current evidence-based recommendations and consensus guidelines.Recent findings: An individualized approach when selecting central venous catheters (CVC) is recommended, considering the estimated duration of need for IV access and the number of lumens needed. Established and novel approaches to minimize complications, including infection and thrombosis, are recognized. These include placement and positioning of the catheter tip under sonographic guidance and the use of antimicrobial lock therapies. Moreover, when possible, salvaging CVCs can reduce the risk of vascular access loss. CVC selection for patients requiring PN depends on several factors. Carefully reviewing an individual patient's clinical characteristics and discussing options is important. Given the increased infection risk, CVC lumens should be minimized. For long-term PN beyond 6 months, using CVCs with skin barriers and larger diameters should be considered.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140863229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Overview of the Potential Role of Nutrition in Mental Disorders in the Light of Advances in Nutripsychiatry. 从营养精神病学的进展看营养在精神障碍中的潜在作用》（An Overview of the Potential Role of Nutrition in Mental Disorders in Light of Advances in Nutripsychiatry）。

IF 4.9 3区医学

Current Nutrition Reports Pub Date : 2024-06-01 Epub Date: 2024-02-08 DOI: 10.1007/s13668-024-00520-4

Nursel Dal, Saniye Bilici

{"title":"An Overview of the Potential Role of Nutrition in Mental Disorders in the Light of Advances in Nutripsychiatry.","authors":"Nursel Dal, Saniye Bilici","doi":"10.1007/s13668-024-00520-4","DOIUrl":"10.1007/s13668-024-00520-4","url":null,"abstract":"Purpose of review: As research on the potential impact of nutrition on mental disorders, a significant component of global disability continues to grow the concepts of \"nutritional psychiatry, psycho-dietetics/nutripsychiatry\" have taken their place in the literature. This review is a comprehensive examination of the literature on the the potential mechanisms between common mental disorders and nutrition and evaluates the effectiveness of dietary interventions.Recent findings: Inflammation, oxidative stress, intestinal microbiota, mitochondrial dysfunction, and neural plasticity are shown as potential mechanisms in the relationship between mental disorders and nutrition. As a matter of fact, neurotrophic factors, which make important contributions to repair mechanisms throughout life, and neuronal plasticity, which plays a role in mental disorders, are affected by nutritional factors. In metabolism, the antioxidant defense system works with nutritional cofactors and phytochemicals. A balanced, planned diet that provides these components is more likely to provide nutrients that increase resilience against the pathogenesis of mental disorders. Nutrition can be considered a risk factor for mental disorders. Therefore, developing public health strategies focused on improving diet may help reduce the global burden of mental disorders and other related diseases.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11133159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139702062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0