Current Nutrition Reports最新文献

The Impact of Diet Quality on COVID-19 Severity and Outcomes-A Scoping Review.

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2025-02-01 DOI: 10.1007/s13668-025-00618-3

Athina Tassakos, Alanna Kloppman, Jimmy Chun Yu Louie

{"title":"The Impact of Diet Quality on COVID-19 Severity and Outcomes-A Scoping Review.","authors":"Athina Tassakos, Alanna Kloppman, Jimmy Chun Yu Louie","doi":"10.1007/s13668-025-00618-3","DOIUrl":"10.1007/s13668-025-00618-3","url":null,"abstract":"Purpose of review: The COVID-19 pandemic, caused by SARS-CoV-2, has highlighted the potential role of nutrition in modifying disease susceptibility and severity. This review aims to systematically evaluate the current evidence on associations between dietary patterns, assessed using diet quality scores (DQS), and COVID-19 severity and outcomes.Recent findings: A comprehensive literature search identified 15 studies across diverse populations. Prospective cohort studies generally found higher diet quality associated with lower COVID-19 infection rates. Case-control studies consistently showed reduced odds of COVID-19 infection and severe illness with adherence to anti-inflammatory dietary patterns, particularly the Mediterranean diet. Cross-sectional data revealed associations between higher DQS and reduced COVID-19 symptom burden and improved prognostic biomarkers. An ecological study demonstrated inverse relationships between national-level diet quality and COVID-19 caseloads. Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and plant-based diet scores were notably predictive of favourable outcomes, even after adjusting for confounders. Conversely, consumption of processed foods high in saturated fats, sugars, and additives was linked to increased COVID-19 complications. Despite these findings, research gaps remain, including the impacts of specific dietary components, effect modifiers across populations, and establishing causality through interventional trials. This review highlights the observational evidence supporting the potential integration of optimal nutrition into pandemic preparedness strategies. Further research is needed to strengthen these findings and inform evidence-based dietary recommendations for COVID-19 prevention and management.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"27"},"PeriodicalIF":4.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Longitudinal Effects of Lifetime Caffeine Consumption on Levels of Depression, Anxiety, and Stress: A Comprehensive Review.

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2025-02-01 DOI: 10.1007/s13668-025-00616-5

Sena Unsal, Nevin Sanlier

{"title":"Longitudinal Effects of Lifetime Caffeine Consumption on Levels of Depression, Anxiety, and Stress: A Comprehensive Review.","authors":"Sena Unsal, Nevin Sanlier","doi":"10.1007/s13668-025-00616-5","DOIUrl":"10.1007/s13668-025-00616-5","url":null,"abstract":"Purpose of review: Caffeine has high bioavailability and a purine-like alkaloid structure. It exerts wide-ranging physiological effects by binding to adenosine receptors throughout the human body. Through the activation of those receptors, it can regulate many physiological events in the body. The impact of caffeine consumption on depression, anxiety, stress, and human health remains unclear, constituting an important knowledge gap. This review was conducted to examine the effects of caffeine consumption on depression, anxiety, and stress levels and to offer some recommendations for its future use.Recent findings: We performed a comprehensive literature search using PubMed, Web of Science and Google Scholar databases for original articles published in recent years on \"caffeine metabolism\", \"caffeine mechanism\", \"anxiety\", \"depression\", \"stress\". Caffeine, which has an antagonistic effect on adenosine, can reduce the risk and symptoms of depression and improve general mental health by modulating the central nervous system and neurotransmitter systems. However, increases in anxiety and stress levels, which are often seen together with depression, are observed due to high-dose caffeine consumption. Caffeine's effects on depression, anxiety, and stress may vary depending on different factors, but the level of consumption is particularly important and attention should be paid to upper limits and reference values while evaluating consumption amounts.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"26"},"PeriodicalIF":4.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11785678/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leaky Gut Syndrome: An Interplay Between Nutrients and Dysbiosis.

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2025-01-31 DOI: 10.1007/s13668-025-00614-7

Ana Beatriz Marcari, Aline Dias Paiva, Claudio Roberto Simon, Maria Emilia Soares Martins Dos Santos

{"title":"Leaky Gut Syndrome: An Interplay Between Nutrients and Dysbiosis.","authors":"Ana Beatriz Marcari, Aline Dias Paiva, Claudio Roberto Simon, Maria Emilia Soares Martins Dos Santos","doi":"10.1007/s13668-025-00614-7","DOIUrl":"https://doi.org/10.1007/s13668-025-00614-7","url":null,"abstract":"Purpose of review: The gut microbiota (GM) is directly related to health and disease. In this context, disturbances resulting from excessive stress, unbalanced diet, alcohol abuse, and antibiotic use, among other factors, can contribute to microbiota imbalance, with significant impacts on host health. This review provides a comprehensive examination of the literature on the influence of diet on dysbiosis and increased intestinal permeability over the past five years.Recent findings: Diet can be considered one of the main modulating factors of GM, impacting its composition and functionality. Excessive consumption of simple carbohydrates, saturated fats, and processed foods appears to be directly linked to dysbiosis, which can lead to intestinal hyperpermeability and leaky gut syndrome. On the other hand, diets primarily composed of food groups such as nuts, vegetables, fruits, fish, and poultry in moderate quantities, along with limited consumption of red and processed meats, are associated with a more diverse, healthier, and beneficial GM for the host. It is worth noticing that the use of prebiotics and probiotics, omega-3 supplementation, polyunsaturated fatty acids, and vitamins A, B, C, D, and E can positively modulate the intestinal microbiota by altering its metabolic activity, microbial composition, and improve intestinal barrier function. This review points to a new perspective regarding individualized dietary intervention and the need to integrate it into several aspects of cellular biology, biochemistry, and microbiology to prescribe more effective diets and thus contribute to patients' comprehensive health.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"25"},"PeriodicalIF":4.6,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Critical Review of Ketogenic Diet Throughout the Cancer Continuum for Neuroglioma: Insights from a Medical Nutrition Therapy (MNT) Perspective.

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2025-01-30 DOI: 10.1007/s13668-025-00609-4

Kristina D Thomopoulos-Titomihelakis, Hillary Sach, Rayna McCann, Qianhui Zhang, Sydney Kurnit, Genesis Codoni De Juan, Amanda Rushing

{"title":"Critical Review of Ketogenic Diet Throughout the Cancer Continuum for Neuroglioma: Insights from a Medical Nutrition Therapy (MNT) Perspective.","authors":"Kristina D Thomopoulos-Titomihelakis, Hillary Sach, Rayna McCann, Qianhui Zhang, Sydney Kurnit, Genesis Codoni De Juan, Amanda Rushing","doi":"10.1007/s13668-025-00609-4","DOIUrl":"https://doi.org/10.1007/s13668-025-00609-4","url":null,"abstract":"PURPOSE OF REVIEW: A Ketogenic diet (KD; a diet comprised of 75% fat, 20% protein and 5% carbohydrates) has gained much popularity in recent years, especially regarding neurogliomas (or \"gliomas\"). This review critically assesses literature on the application of KD throughout the cancer continuum from a Medical Nutrition Therapy (MNT) perspective. RECENT FINDINGS: 2021 revised classification standards for Central Nervous System (CNS) tumors are available. Despite research on KD and CNS tumors increasing, the role and benefits of MNT to augment side effects of traditional treatment and KD throughout the cancer continuum remain unclear. Glioma cancer survivors may benefit from a KD. It is a challenging, yet feasible non-pharmacological adjuvant approach. More research is needed regarding KD for prevention and post-treatment of glioma. Standard guidelines regarding macronutrient composition of KD for glioma are warranted. The need and benefits of nutritional guidance provided by a Registered Dietitian Nutritionist (RD or RDNs) during adherence to KD are understated.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"24"},"PeriodicalIF":4.6,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Anthocyanins on Cognition: A Systematic Review and Meta-analysis of Randomized Clinical Trial Studies in Cognitively Impaired and Healthy Adults.

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2025-01-29 DOI: 10.1007/s13668-024-00595-z

Elnaz Lorzadeh, Katrina Weston-Green, Steven Roodenrys, Vinicius do Rosario, Katherine Kent, Karen Charlton

{"title":"The Effect of Anthocyanins on Cognition: A Systematic Review and Meta-analysis of Randomized Clinical Trial Studies in Cognitively Impaired and Healthy Adults.","authors":"Elnaz Lorzadeh, Katrina Weston-Green, Steven Roodenrys, Vinicius do Rosario, Katherine Kent, Karen Charlton","doi":"10.1007/s13668-024-00595-z","DOIUrl":"10.1007/s13668-024-00595-z","url":null,"abstract":"Purpose of the review: Clinical trials suggest that dietary anthocyanins may enhance cognitive function. This systematic literature review and meta-analysis aimed to identify the effect of anthocyanin on cognition and mood in adults.Recent findings: Using a random-effects model, Hedge's g scores were calculated to estimate the effect size. Across 30 randomized controlled trials, fourteen (n = 733 participants) met the criteria for meta-analysis following PRISMA guidelines (Registration number: CRD42021279470). Qualitative synthesis showed improvements in multiple domains after anthocyanin intake: short-term memory, verbal learning and working memory, executive function, visual-spatial function, psychomotor skills, attention and semantic memory. Four of 15 studies reported significant mood improvements, including anti-fatigue and reduced anxiety and depression scores. However, there were no significant effects for working memory (Hedges's g = -0.183, 95% CI = -0.407 to 0.041, P = 0.110), verbal learning (Hedges's g = 0.054, 95% CI = -0.215 to 0.324, P = 0.69), immediate memory (Hedges's g = 0.196, 95% CI = -0.242 to 0.633, P = 0.38) and delayed memory (Hedges's g = -0.188, 95% CI = -0.629 to -0.252, P = 0.402) according to the meta-analysis. This review suggests potential benefits of anthocyanin intake on cognition and mood. However, in meta-analysis of 14 eligible studies, effects on working, immediate, delayed memory and verbal learning were not significant, likely due to study heterogeneity. Recommendations for future study designs are discussed.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"23"},"PeriodicalIF":4.6,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11775034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143058257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current State of Research on Health-Promoting Functional Properties in Berry-Based Foods.

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2025-01-25 DOI: 10.1007/s13668-025-00615-6

Rocío Corfield, Milagros Gomez Mattson, Oscar E Pérez, Daniela Salvatori, Carolina Schebor

{"title":"Current State of Research on Health-Promoting Functional Properties in Berry-Based Foods.","authors":"Rocío Corfield, Milagros Gomez Mattson, Oscar E Pérez, Daniela Salvatori, Carolina Schebor","doi":"10.1007/s13668-025-00615-6","DOIUrl":"https://doi.org/10.1007/s13668-025-00615-6","url":null,"abstract":"Purpose of review: This review aims to consolidate recent findings on the development and functional validation of berry-based foods while proposing guidelines for future advancements.Recent findings: Current investigations on berry-based functional foods (dairy and bakery products, snacks, etc.) emphasize their potential health benefits, including antioxidant effects, glycemic control, enzyme modulation, among others. Although there is valuable information on the capacity of berry-derived food products to confer health benefits, only 10% of the reviewed publications reached the final validation stage of the formulated product through in vivo assays. The analyzed publications were classified according to the approach used to study the functional potential of the developed berry-based products, considering simple spectrophotometric analysis, in vitro biological studies, and in vivo studies. Guidelines for a successful development of berry-based health enhancing foods were presented. Future research should include functional validation of final food products and confirm their bioactivity through in vivo studies.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"22"},"PeriodicalIF":4.6,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Nutrition and Nutritional Supplements in the Prevention and Treatment of Malnutrition in Chronic Obstructive Pulmonary Disease: Current Approaches in Nutrition Therapy.

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2025-01-25 DOI: 10.1007/s13668-025-00613-8

Tuğba Tuna, Gülhan Samur

{"title":"The Role of Nutrition and Nutritional Supplements in the Prevention and Treatment of Malnutrition in Chronic Obstructive Pulmonary Disease: Current Approaches in Nutrition Therapy.","authors":"Tuğba Tuna, Gülhan Samur","doi":"10.1007/s13668-025-00613-8","DOIUrl":"10.1007/s13668-025-00613-8","url":null,"abstract":"Purpose of review: Malnutrition is a significant comorbidity in Chronic Obstructive Pulmonary Disease (COPD), contributing to disease progression and reduced quality of life. This narrative review examines the role of nutritional therapy in the prevention and management of malnutrition in COPD, emphasizing evidence-based approaches and their clinical implications.Recent findings: COPD patients face increased metabolic demands, systemic inflammation, and reduced dietary intake, resulting in muscle wasting, sarcopenia, and cachexia. Recent evidence highlights the efficacy of targeted nutritional strategies, including essential amino acid supplementation, omega-3 fatty acids, vitamin D, and antioxidants, in improving respiratory function, muscle strength, and patient well-being. Comprehensive nutritional assessments and personalized interventions are increasingly recognized as critical components of COPD care. However, long-term efficacy data remain limited. Nutritional therapy plays a pivotal role in managing malnutrition and improving clinical outcomes in COPD. This review synthesizes the latest evidence, identifies gaps in current research, and proposes strategies for integrating personalized nutrition into COPD care. Future studies are needed to establish the long-term benefits of these interventions and to develop tailored nutritional guidelines for COPD patients.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"21"},"PeriodicalIF":4.6,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mitigating Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD): The Role of Bioactive Phytoconstituents in Indian Culinary Spices.

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2025-01-22 DOI: 10.1007/s13668-024-00598-w

Pervej Alom Barbhuiya, Ameena Ahmed, Partha Pratim Dutta, Saikat Sen, Manash Pratim Pathak

{"title":"Mitigating Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD): The Role of Bioactive Phytoconstituents in Indian Culinary Spices.","authors":"Pervej Alom Barbhuiya, Ameena Ahmed, Partha Pratim Dutta, Saikat Sen, Manash Pratim Pathak","doi":"10.1007/s13668-024-00598-w","DOIUrl":"https://doi.org/10.1007/s13668-024-00598-w","url":null,"abstract":"Purpose of review: The term metabolic dysfunction-associated steatotic liver disease (MASLD) refers to a group of progressive steatotic liver conditions that include metabolic dysfunction-associated steatohepatitis (MASH), which has varying degrees of liver fibrosis and may advance to cirrhosis, and independent hepatic steatosis. MASLD has a complex underlying mechanism, with patients exhibiting diverse causes and phases of the disease. India has a pool prevalence of MASLD of 38.6% in adults. In 2023, the term NAFLD has been redefined and changed to MASLD. Currently, there are no drugs approved by the FDA for the treatment of MASLD. This study investigates the potential of bioactive phytoconstituents present in spices as a therapeutic approach for MASLD. Moreover, it offers comprehensive data on several pre-clinical studies of bioactive phytoconstituents derived from spices that primarily focus on treating obesity-associated MASLD.Recent findings: Spices include a high amount of bioactive chemicals and several research have indicated their diverse pharmacological activities. Bioactive phytoconstituents from common Indian spices like cinnamic acid, eugenol, curcumin, allicin, 6-gingerols, capsaicin, piperine, eucalyptol, trigonelline, and linalool have been reported to exhibit anti-MASLD effects both in-vivo and in-vitro. Bioactive phytoconstituents from different culinary species of India have shown promising potential against MASLD in pre-clinical status. Further clinical studies on a large scale would be beneficial for paving the path to the development of a new drug which is the need of time.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"20"},"PeriodicalIF":4.6,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143058254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of Grape-Based Interventions on Cognitive and Mental Health: Evidence From Human Trials. 基于葡萄的认知和心理健康干预的有效性：来自人体试验的证据。

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2025-01-16 DOI: 10.1007/s13668-025-00612-9

Keotshepile Precious Bojang, Manchana Varalakshmi

{"title":"Effectiveness of Grape-Based Interventions on Cognitive and Mental Health: Evidence From Human Trials.","authors":"Keotshepile Precious Bojang, Manchana Varalakshmi","doi":"10.1007/s13668-025-00612-9","DOIUrl":"https://doi.org/10.1007/s13668-025-00612-9","url":null,"abstract":"Purpose of review: This review evaluates current research on grape-based interventions and their impact on cognitive and mental health. It also explores the putative mechanisms by which the grape-derived compounds might modulate cognitive function. The growing prevalence of cognitive decline and mental health disorders necessitates exploring novel dietary approaches. Grapes, rich in polyphenols, have demonstrated potential benefits in preclinical studies. However, translating these findings to humans remains an ongoing endeavor.Recent findings: Recent clinical trials complement existing observational data, suggesting a positive influence of grape consumption on cognition, particularly in areas of memory, learning, and overall cognitive function and emotional well-being. The potential mechanisms involve the antioxidant and anti-inflammatory properties of grapes, which may mitigate neuroinflammation and protect brain cells from free radical damage. Evidence from existing research suggests that grape based interventions may improve cognitive performance through several neuroprotective mechanisms; however, further investigation is needed to understand the protective effects of grape-based interventions on brain function and mental health. Large-scale trials to assess the long-term effects and safety profile of grape interventions are required. Additionally, extensive epidemiological research is needed to confirm the effect of grape interventions on cognitive health and to determine the best beneficial dosage and duration of supplementations to maximise cognitive benefits.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"19"},"PeriodicalIF":4.6,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutrition and Huntington's Disease- A Review of Current Practice and Theory. 营养与亨廷顿氏病——当前实践与理论综述。

IF 4.6 3区医学

Current Nutrition Reports Pub Date : 2025-01-16 DOI: 10.1007/s13668-025-00610-x

Ann Gaba

引用次数: 0