Neil Mistry, Logan T Cowan, Hani M Samawi, Amenah Qotineh, Kelly L Sullivan
{"title":"Association of Vitamins and their Interactions on Depression: A Review.","authors":"Neil Mistry, Logan T Cowan, Hani M Samawi, Amenah Qotineh, Kelly L Sullivan","doi":"10.1007/s13668-025-00686-5","DOIUrl":"10.1007/s13668-025-00686-5","url":null,"abstract":"<p><strong>Purpose of review: </strong>Depression is highly prevalent in the United States. Literature has investigated common demographic risk factors and pharmacological and non-pharmacological treatments. The effects of vitamins and their interactions on depression prevalence and symptoms has gained interest, especially in the context of a large representative sample. The review aims to evaluate the literature concerning individual vitamins and their association with depression.</p><p><strong>Recent findings: </strong>Several observational studies have been conducted to determine the effects of individual vitamins on depression. These studies have conflicting results regarding the impact and magnitude of vitamin effects, and previous studies evaluating the effect of vitamin interactions on depression have limited generalizability. Despite pharmacologic and biological rationale supporting the potential role of vitamins in combating depression, results of studies evaluating vitamin intake and depression in humans are inconsistent and limited. Further research is needed to assess the link between nutrition and depression in robust populations, particularly in groups at risk for or suffering from depression.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"95"},"PeriodicalIF":5.5,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144717714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intermittent Fasting for the Prevention of Cardiovascular Disease Risks: Systematic Review and Network Meta-Analysis.","authors":"Kelemu Tilahun Kibret, Anna Peeters, Teketo Kassaw Tegegne, Yonatan Moges Mesfin, Melanie Nichols","doi":"10.1007/s13668-025-00684-7","DOIUrl":"10.1007/s13668-025-00684-7","url":null,"abstract":"<p><strong>Context: </strong>While several studies have assessed the potential effect of intermittent fasting on reducing cardiovascular risks, the findings are inconclusive.</p><p><strong>Objective: </strong>To compare the relative effectiveness of intermittent fasting methods in reducing key cardiovascular risks.</p><p><strong>Methods: </strong>Studies were searched from Medline, Embase, Cochrane Library Central and Global Health to identify studies that enrolled adults (≥ 18 years) to intermittent fasting methods and reported effects on one of the six specified cardiovascular risk factors. We performed a random-effects network meta-analysis using a frequentist framework. Outcomes were reported as mean differences (MD) with their corresponding 95% confidence intervals (CI).</p><p><strong>Results: </strong>Fifty-six studies were included in the analysis. With high certainty of evidence, modified alternate-day fasting was found to be the most effective intervention compared to a usual diet in reducing body weight (MD= -5.18 kg; 95% CI: -7.04, -3.32), waist circumference (-3.55 cm; -5.66, -1.45), systolic blood pressure (-7.24 mmHg; -11.90, -2.58), diastolic blood pressure (-4.70 mmHg; -8.46, -0.95). With high certainty, time-restricted eating was the most effective intervention compared to usual diet in reducing fat-free mass (-0.82 kg; -1.46, -0.17), waist circumference (-3.00 cm; -4.50, -1.51), diastolic blood pressure (-3.24 mmHg; -4.69, -1.79) and fasting plasma glucose (-3.74 mg/dL; -6.01, -1.46).</p><p><strong>Conclusions: </strong>Modified alternate-day fasting, and time-restricted eating appear to be promising approaches for reducing most cardiovascular risk factors. These intermittent fasting methods may be considered as potential components of lifestyle interventions aimed at managing cardiovascular disease risk factors. However, further long-term randomised controlled trials comparing intermittent fasting methods are needed to confirm their efficacy and assess their safety over time.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"93"},"PeriodicalIF":5.5,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12289860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144697845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariana de Moura E Dias, Madalena Geralda Cupertino Ribeiro, Ana Claudia Pelissari Kravchychyn, Helen Hermana Miranda Hermsdorff
{"title":"Microbiota-Gut-Brain Axis and Impaired Satiety in Individuals with Obesity: A Potentially Bidirectional Association.","authors":"Mariana de Moura E Dias, Madalena Geralda Cupertino Ribeiro, Ana Claudia Pelissari Kravchychyn, Helen Hermana Miranda Hermsdorff","doi":"10.1007/s13668-025-00682-9","DOIUrl":"https://doi.org/10.1007/s13668-025-00682-9","url":null,"abstract":"","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"92"},"PeriodicalIF":4.6,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jithinraj Edakkanambeth Varayil, Suzette J Bielinski, Manpreet S Mundi, Sara L Bonnes, Bradley R Salonen, Ryan T Hurt
{"title":"Artificial Intelligence in Clinical Nutrition: Bridging Data Analytics and Nutritional Care.","authors":"Jithinraj Edakkanambeth Varayil, Suzette J Bielinski, Manpreet S Mundi, Sara L Bonnes, Bradley R Salonen, Ryan T Hurt","doi":"10.1007/s13668-025-00680-x","DOIUrl":"https://doi.org/10.1007/s13668-025-00680-x","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review explores how artificial intelligence can help advance clinical nutrition and address nutrition education and practice challenges. It highlights the role of AI, mainly through advanced clinical decision-making using generative AI, in supporting clinicians as they develop personalized nutrition interventions for individual patients. Furthermore, the review discusses how AI technologies are helping to close the knowledge gap in nutrition and delivering real-time, evidence-based insights to healthcare professionals.</p><p><strong>Recent findings: </strong>AI processes, such as machine learning and natural language processing, have shown promising results in predicting nutritional outcomes and complications, such as malnutrition and central line-associated bloodstream infections. Studies highlight the capability of AI to efficiently process large datasets, identify key risk factors, and provide real-time support to clinicians. Furthermore, AI can personalize educational content, making complex nutritional concepts more accessible. AI has demonstrated multiple potential use cases in nutrition. However, much work still needs to be done to evaluate its accuracy, accessibility and ethical considerations.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"91"},"PeriodicalIF":4.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aneta Sokal-Dembowska, Sara Jarmakiewicz-Czaja, Jacek Tabarkiewicz, Rafał Filip
{"title":"Nitrate and Nitrite in the Diet: Protective and Harmful Effects in Health and Disease.","authors":"Aneta Sokal-Dembowska, Sara Jarmakiewicz-Czaja, Jacek Tabarkiewicz, Rafał Filip","doi":"10.1007/s13668-025-00678-5","DOIUrl":"10.1007/s13668-025-00678-5","url":null,"abstract":"","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"89"},"PeriodicalIF":4.6,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12209013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Georgy Leonov, Elena Livantsova, Yurgita Varaeva, Antonina Starodubova
{"title":"Probiotics and Prebiotics in Post-Myocardial Infarction Rehabilitation: Mechanisms, Benefits, and Future Directions.","authors":"Georgy Leonov, Elena Livantsova, Yurgita Varaeva, Antonina Starodubova","doi":"10.1007/s13668-025-00679-4","DOIUrl":"10.1007/s13668-025-00679-4","url":null,"abstract":"<p><strong>Purpose of review: </strong>Myocardial infarction (MI) remains a leading cause of morbidity and mortality worldwide, and rehabilitation is essential to improve patient outcomes and reduce the risk of recurrent cardiovascular events. This review aims to summarize research on the gut-heart axis and the therapeutic potential of probiotics and prebiotics in MI rehabilitation, highlighting their ability to modulate gut microbiota composition and activity to benefit cardiovascular health.</p><p><strong>Recent findings: </strong>Recent studies have identified the gut microbiome as a critical modulator of myocardial health, with dysbiosis-an imbalance in microbial populations-associated with increased production of proinflammatory metabolites such as trimethylamine-N-oxide (TMAO), which exacerbate endothelial dysfunction and thrombosis in MI patients. Studies show that probiotic strains and prebiotics can improve blood lipid profiles, regulate blood pressure, inhibit the progression of endothelial dysfunction, promote the growth of beneficial bacteria, and increase cardioprotective short-chain fatty acids. The use of probiotics and prebiotics in MI patients may be of advantage in cardiac rehabilitation. Probiotics and prebiotics have been shown to offer potential benefits in mitigating inflammation, improving endothelial function, and optimizing metabolic health. These microbiome-targeted strategies may complement existing rehabilitation approaches, potentially reducing the risk of recurrent cardiovascular events and improving long-term outcomes for patients with MI. However, further research is necessary to elucidate the underlying mechanisms and substantiate the clinical efficacy of these therapeutic interventions.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"88"},"PeriodicalIF":4.6,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yin Liew, Leanne J Brown, Renaye Madden, Laura Alston, Lisa Urquhart, Susan Heaney, Tracy Schumacher
{"title":"Understanding the Use of Community Involvement in Rural Food Environment Modifications: A Systematic Review.","authors":"Yin Liew, Leanne J Brown, Renaye Madden, Laura Alston, Lisa Urquhart, Susan Heaney, Tracy Schumacher","doi":"10.1007/s13668-025-00674-9","DOIUrl":"10.1007/s13668-025-00674-9","url":null,"abstract":"","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"87"},"PeriodicalIF":4.6,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12206173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michelle Coutiño Díaz, Arnold Prieto Martínez, Reza Zare, Ali Ali Redha, Scott C Forbes
{"title":"Evidence-Based Supplementation Strategies for Wrestlers: A Systematic Review.","authors":"Michelle Coutiño Díaz, Arnold Prieto Martínez, Reza Zare, Ali Ali Redha, Scott C Forbes","doi":"10.1007/s13668-025-00672-x","DOIUrl":"10.1007/s13668-025-00672-x","url":null,"abstract":"<p><strong>Background: </strong>Wrestling is a popular combat sport that requires muscular strength, power, agility, and endurance. Weight classes have motivated wrestlers to compete at a lower weight to optimise power-to-weight ratio and performance. To achieve these characteristics, athletes may use dietary supplements, however, their efficacy in wrestlers has not been systematically evaluated.</p><p><strong>Objective: </strong>The purpose was to systematically review the literature to determine the efficacy of dietary supplements to improve body composition, physiological status, and performance in wrestlers.</p><p><strong>Methods: </strong>A systematic search was conducted in PubMed, ProQuest Medline, Web of Science, Cochrane Library, and Scopus on the 21st of January 2024 and updated on the 6th of January 2025. Studies were included if the participants were healthy wrestlers ingesting any type of dietary supplement in comparison to a control. Data associated with intervention type and characteristics, target populations, outcomes, and analysis methods were extracted.</p><p><strong>Results: </strong>A total of 24 eligible original articles were included that assessed various supplementation strategies on body composition, exercise performance, and metabolic markers in wrestlers. Individual studies revealed significant effects of sodium citrate, creatine monohydrate, spirulina, green tea and oolong tea extracts, and branched-chain amino acids on body mass or composition. β-Hydroxy-β-methylbutyrate (HMB-FA), creatine monohydrate, and iron supplementation improved recovery and may improve exercise performance. Beet-root juice supplementation enhanced muscular strength and balance. BCAA supplementation produced mixed results on muscle damage biomarkers and performance, while sodium citrate, creatine, and spirulina can act as buffering agents. Thyme tea appears to improve antioxidant capacity.</p><p><strong>Conclusions: </strong>Overall, individual studies show some promise for several dietary supplements to alter body mass and body composition, improve exercise recovery and performance, delay fatigue, and modify serum biomarkers; nevertheless, effect sizes were often small, and results were often mixed.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"86"},"PeriodicalIF":4.6,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12198300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}