Current Nutrition Reports最新文献_第10页

The Uterine Environment and Childhood Obesity Risk: Mechanisms and Predictions. 子宫环境与儿童肥胖风险:机制和预测。

IF 4.9 3区医学

Current Nutrition Reports Pub Date : 2023-09-01 DOI: 10.1007/s13668-023-00482-z

Andreea Cristian, Jane L Tarry-Adkins, Catherine E Aiken

{"title":"The Uterine Environment and Childhood Obesity Risk: Mechanisms and Predictions.","authors":"Andreea Cristian, Jane L Tarry-Adkins, Catherine E Aiken","doi":"10.1007/s13668-023-00482-z","DOIUrl":"https://doi.org/10.1007/s13668-023-00482-z","url":null,"abstract":"Purpose of review: Childhood obesity is a growing health problem in many populations, hence the urgent need to unravel the underlying mechanisms. Some evidence suggests that exposure to suboptimal intrauterine environments can program foetal metabolic health, with adverse consequences in later life, including susceptibility to childhood obesity.Findings: Factors such as high and low foetal birth weight, excessive gestational-weight-gain, maternal stress and smoking are all associated with increased risk of childhood obesity in observational studies. Animal models, where both genetic background and the postnatal environment can be carefully controlled, suggest that several different mechanisms, including epigenetic changes, dysregulation of adipose tissue development and programming of appetite, may be key drivers of developmental programming of childhood obesity. However, the influence of genetics and the post-natal environment are much more difficult to disentangle as independent effects in human studies, which are also complicated by low follow-up rates. Suboptimal intrauterine environments interact with maternal and foetal genetics and with the postnatal environment to contribute to the risk of childhood obesity. Maternal metabolic challenges, for example obesity and insulin resistance, contribute to the risk of foetal overgrowth and subsequent adiposity in childhood. To protect the long-term health of populations, research focusing on effective means of identifying and intervening in the transgenerational cycle of childhood obesity is required.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10054169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Influence of Grandparents on Children's Dietary Health: A Narrative Review. 祖父母对儿童饮食健康的影响:一个叙述性的回顾。

IF 4.9 3区医学

Current Nutrition Reports Pub Date : 2023-09-01 DOI: 10.1007/s13668-023-00483-y

Michelle I Jongenelis, Timothy Budden

引用次数: 1

IF 4.9 3区医学

Current Nutrition Reports Pub Date : 2023-09-01 DOI: 10.1007/s13668-023-00474-z

Şerife Akpınar, Nilüfer Acar Tek

引用次数: 0

Mitochondrial Damage and Hypertension: Another Dark Side of Sodium Excess. 线粒体损伤和高血压:钠过量的另一个阴暗面。

IF 4.9 3区医学

Current Nutrition Reports Pub Date : 2023-09-01 DOI: 10.1007/s13668-023-00486-9

Baris Afsar, Rengin Elsurer Afsar

{"title":"Mitochondrial Damage and Hypertension: Another Dark Side of Sodium Excess.","authors":"Baris Afsar, Rengin Elsurer Afsar","doi":"10.1007/s13668-023-00486-9","DOIUrl":"https://doi.org/10.1007/s13668-023-00486-9","url":null,"abstract":"Purpose of review: Essential or primary hypertension (HT) is a worldwide health problem with no definitive cure. Although the exact pathogenesis of HT is not known, genetic factors, increased renin-angiotensin and sympathetic system activity, endothelial dysfunction, oxidative stress, and inflammation play a role in its development. Environmental factors such as sodium intake are also important for BP regulation, and excess sodium intake in the form of salt (NaCl, sodium chloride) increases blood pressure in salt-sensitive people. Excess salt intake increases extracellular volume, oxidative stress, inflammation, and endothelial dysfunction. Recent evidence suggests that increased salt intake also disturbs mitochondrial function both structurally and functionally which is important as mitochondrial dysfunction is associated with HT. In the current review, we have summarized the experimental and clinical data regarding the impact of salt intake on mitochondrial structure and function.Recent findings: Excess salt intake damage mitochondrial structure (e.g., shorter mitochondria with less cristae, increased mitochondrial fission, increased mitochondrial vacuolization). Functionally, high salt intake impairs mitochondrial oxidative phosphorylation and electron transport chain, ATP production, mitochondrial calcium homeostasis, mitochondrial membrane potential, and mitochondrial uncoupling protein function. Excess salt intake also increases mitochondrial oxidative stress and modifies Krebs cycle protein expressions. Studies have shown that high salt intake impairs mitochondrial structure and function. These maladaptive mitochondrial changes facilitate the development of HT especially in salt-sensitive individuals. High salt intake impairs many functional and structural components of mitochondria. These mitochondrial alterations along with increased salt intake promote the development of hypertension.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10056448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pathophysiology and Nutritional Approaches in Polycystic Ovary Syndrome (PCOS): A Comprehensive Review. 多囊卵巢综合征(PCOS)的病理生理和营养途径:综合综述。

IF 4.9 3区医学

Current Nutrition Reports Pub Date : 2023-09-01 DOI: 10.1007/s13668-023-00479-8

M Di Lorenzo, N Cacciapuoti, M S Lonardo, G Nasti, C Gautiero, A Belfiore, B Guida, M Chiurazzi

{"title":"Pathophysiology and Nutritional Approaches in Polycystic Ovary Syndrome (PCOS): A Comprehensive Review.","authors":"M Di Lorenzo, N Cacciapuoti, M S Lonardo, G Nasti, C Gautiero, A Belfiore, B Guida, M Chiurazzi","doi":"10.1007/s13668-023-00479-8","DOIUrl":"https://doi.org/10.1007/s13668-023-00479-8","url":null,"abstract":"Purpose of review: Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder in women of reproductive age worldwide. This disease causes menstrual, metabolic, and biochemical abnormalities such as hyperandrogenism, oligo-anovulatory menstrual cycles, polycystic ovary, hyperleptinemia, insulin resistance (IR), and cardiometabolic disorders, often associated with overweight or obesity and visceral adiposity.Recent findings: The etiology and pathophysiology of PCOS are not yet fully understood, but insulin seems to play a key role in this disease. PCOS shares an inflammatory state with other chronic diseases such as obesity, type II diabetes, and cardiovascular diseases; however, recent studies have shown that a healthy nutritional approach can improve IR and metabolic and reproductive functions, representing a valid therapeutic strategy to ameliorate PCOS symptomatology. This review aimed to summarize and collect evidence about different nutritional approaches such as the Mediterranean diet (MedDiet) and the ketogenic diet (KD), as well as bariatric surgery and nutraceutical supplementation as probiotics, prebiotics, and synbiotics, among the others, used in patients with PCOS.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10060832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Butyrate: More Than a Short Chain Fatty Acid. 丁酸盐:不仅仅是一种短链脂肪酸。

IF 4.9 3区医学

Current Nutrition Reports Pub Date : 2023-06-01 DOI: 10.1007/s13668-023-00461-4

Osman Mohamed Elfadil, Manpreet S Mundi, Marwa G Abdelmagid, Ankitaben Patel, Nishant Patel, Robert Martindale

引用次数: 3

Dairy Milk Protein-Derived Bioactive Peptides: Avengers Against Metabolic Syndrome. 牛奶蛋白衍生的生物活性肽:对抗代谢综合征的复仇者。

IF 4.9 3区医学

Current Nutrition Reports Pub Date : 2023-06-01 DOI: 10.1007/s13668-023-00472-1

Pankaj Koirala, Merina Dahal, Sampurna Rai, Milan Dhakal, Nilesh Prakash Nirmal, Sajid Maqsood, Fahad Al-Asmari, Athisaya Buranasompob

{"title":"Dairy Milk Protein-Derived Bioactive Peptides: Avengers Against Metabolic Syndrome.","authors":"Pankaj Koirala, Merina Dahal, Sampurna Rai, Milan Dhakal, Nilesh Prakash Nirmal, Sajid Maqsood, Fahad Al-Asmari, Athisaya Buranasompob","doi":"10.1007/s13668-023-00472-1","DOIUrl":"https://doi.org/10.1007/s13668-023-00472-1","url":null,"abstract":"Purpose of review: Metabolic syndrome is continuously increasing among the world's populations. Metabolic syndrome is a medical condition in which individuals suffer from high blood pressure, high blood glucose levels, and obesity. The in vitro and in vivo bioactivities of dairy milk protein-derived peptides (MPDP) have proven their potential as an excellent natural alternative to the current medical treatment for metabolic syndrome. In this context, the review discussed the major protein source of dairy milk and provides current knowledge on the novel and integrated approach to MPDP production. A detailed comprehensive discussion is provided on the current state of knowledge regarding the in vitro and in vivo bioactivities of MPDP against metabolic syndrome. In addition, the most important aspect of digestive stability, allergenicity, and further directions for MPDP application is provided.Recent findings: The major proteins found in milk are casein and whey, while a minor portion of serum albumin and transferrin are reported. Upon gastrointestinal digestion or enzymatic hydrolysis, these proteins produce peptides with various biological activities including antioxidative, antiinflammatory, antihypertensive, antidiabetic, and antihypercholesterolemic, which could help in ameliorating metabolic syndrome. Bioactive MPDP has the potential to curtail metabolic syndrome and potentially act as a safe replacement for chemical drugs with fewer side effects.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9675192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary Intake and Systemic Inflammation: Can We Use Food as Medicine? 饮食摄入与全身性炎症:我们能以食物为药吗?

IF 4.9 3区医学

Current Nutrition Reports Pub Date : 2023-06-01 DOI: 10.1007/s13668-023-00458-z

Erica Graff, Shyam Vedantam, Mary Parianos, Nabiha Khakoo, Marissa Beiling, Michelle Pearlman

引用次数: 2

Women in Nutrition Science: A Biographical Review. 营养科学中的女性:传记回顾。

IF 4.9 3区医学

Current Nutrition Reports Pub Date : 2023-06-01 DOI: 10.1007/s13668-023-00455-2

Apeksha Shah, Ajanta J Raman, Dustin R Neel, Caleb J Kelly

引用次数: 0

Synbiotics and Surgery: Can Prebiotics and Probiotics Affect Inflammatory Surgical Outcomes? 合成菌与外科:益生元和益生菌能影响炎性手术结果吗?

IF 4.9 3区医学

Current Nutrition Reports Pub Date : 2023-06-01 DOI: 10.1007/s13668-023-00464-1

Kristin Trone, Shahrose Rahman, Caitlin Homberger Green, Carla Venegas, Robert Martindale, Andrea Stroud

{"title":"Synbiotics and Surgery: Can Prebiotics and Probiotics Affect Inflammatory Surgical Outcomes?","authors":"Kristin Trone, Shahrose Rahman, Caitlin Homberger Green, Carla Venegas, Robert Martindale, Andrea Stroud","doi":"10.1007/s13668-023-00464-1","DOIUrl":"https://doi.org/10.1007/s13668-023-00464-1","url":null,"abstract":"Purpose of review: Prebiotics, probiotics, and synbiotics have received increasing attention over the years for their beneficial impact on the gut microbiome and for their systemic anti-inflammatory effects. They have also been shown to improve surgical outcomes. Here, we review the inflammatory effects of surgery as well as the data which suggests a benefit of prebiotics, probiotics, and synbiotics taken in the perioperative period.Recent findings: Synbiotics and fermented foods may have an even greater anti-inflammatory effect than probiotics or prebiotics alone. Recent data suggest that the anti-inflammatory effects and microbiome changes brought on by prebiotics, probiotics, and synbiotics have the potential to improve surgical outcomes. We highlight the potential to alter systemic inflammation, surgical and hospital-acquired infections, colorectal cancer formation, recurrence, and anastomotic leak. Synbiotics could also impact metabolic syndrome. Prebiotics, probiotics, and especially synbiotics may be extremely beneficial when taken in the perioperative period. Even short-term gut microbiome pre-habilitation could alter surgical outcomes significantly.","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10026962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1