Current Cardiology Reports最新文献

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Diagnosis and Management of Acute Coronary Syndrome Patients Without Obstructive Epicardial Stenosis.
IF 3.1 3区 医学
Current Cardiology Reports Pub Date : 2025-01-30 DOI: 10.1007/s11886-025-02191-1
Khaled Ziada, Hassan Alkhawam, Haidar Hajeh, Malak Modi, Tarek Helmy
{"title":"Diagnosis and Management of Acute Coronary Syndrome Patients Without Obstructive Epicardial Stenosis.","authors":"Khaled Ziada, Hassan Alkhawam, Haidar Hajeh, Malak Modi, Tarek Helmy","doi":"10.1007/s11886-025-02191-1","DOIUrl":"10.1007/s11886-025-02191-1","url":null,"abstract":"<p><strong>Purpose of review: </strong>What is the pathophysiology and clinical findings as well as management of patients presenting with INOCA/MINOCA (Ischemia/Myocardial Infarction with Non-Obstructive Coronary Arteries).</p><p><strong>Recent findings: </strong>INOCA/MINOCA has a complex pathophysiology. In this review article, we aim to summarize the complex pathophysiology and clinical diagnosis, and review the current management options.</p>","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"43"},"PeriodicalIF":3.1,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11782288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimizing Sedation Strategies in the Cardiac ICU: Induction, Maintenance and Weaning.
IF 3.1 3区 医学
Current Cardiology Reports Pub Date : 2025-01-29 DOI: 10.1007/s11886-024-02161-z
Laith Alhuneafat, Effimia Maria Zacharia, Pratik Velangi, Jason Bartos, Alejandra Gutierrez
{"title":"Optimizing Sedation Strategies in the Cardiac ICU: Induction, Maintenance and Weaning.","authors":"Laith Alhuneafat, Effimia Maria Zacharia, Pratik Velangi, Jason Bartos, Alejandra Gutierrez","doi":"10.1007/s11886-024-02161-z","DOIUrl":"https://doi.org/10.1007/s11886-024-02161-z","url":null,"abstract":"<p><strong>Purpose of review: </strong>We aim to summarize the available literature guiding tailored sedation practices for specific conditions encountered in the Cardiovascular Intensive Care Unit (CICU).</p><p><strong>Recent findings: </strong>Data specific for the CICU population is lacking. Preclinical data and observational studies guide sedation approaches for specific pathologies that we have used to generate a guideline for sedative choice for various scenarios. We discuss the challenges associated with extubation and highlight the importance of spontaneous breathing trials and role of non invasive ventilation. Understanding the underlying pathology and the effects of sedation and positive pressure ventilation is the base to guide induction and sedation management for patients in the CICU. There is a pressing need for further research to generate high quality clinical data to improve sedation techniques in the CICU.</p>","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"42"},"PeriodicalIF":3.1,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143058287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The ImageGuideEcho Registry: Using Data Science to Understand and Improve Echocardiography.
IF 3.1 3区 医学
Current Cardiology Reports Pub Date : 2025-01-29 DOI: 10.1007/s11886-025-02199-7
Nicholas Spetko, Jessica Oribabor, Emeka Anyanwu, Thomas B Iii Tyler, Deily F Rodriguez, David Ouyang, Jordan B Strom
{"title":"The ImageGuideEcho Registry: Using Data Science to Understand and Improve Echocardiography.","authors":"Nicholas Spetko, Jessica Oribabor, Emeka Anyanwu, Thomas B Iii Tyler, Deily F Rodriguez, David Ouyang, Jordan B Strom","doi":"10.1007/s11886-025-02199-7","DOIUrl":"10.1007/s11886-025-02199-7","url":null,"abstract":"<p><strong>Purpose of review: </strong>To provide a contemporary update on the American Society of Echocardiography's ImageGuideEcho Registry and present a case study of an individual institution's experience with enrollment.</p><p><strong>Recent findings: </strong>Technical innovation in clinical echocardiography has expanded the impact of echocardiography in cardiovascular care and provides new opportunities to leverage clinical data to inform quality improvement initiatives and research. The ImageGuideEcho Registry is the first echocardiography-specific imaging registry in the United States and provides a data infrastructure for quality improvement and multicenter research. The ImageGuideEcho Registry continues to grow, offering a window into echocardiography care across the United States in a variety of practice settings. This early experience highlights its value, opportunities, and ongoing challenges. Continued innovation, such as the addition of primary images, will further add to the substantial value of the registry.</p>","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"41"},"PeriodicalIF":3.1,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11779749/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143058288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contemporary Insights into LMNA Cardiomyopathy.
IF 3.1 3区 医学
Current Cardiology Reports Pub Date : 2025-01-27 DOI: 10.1007/s11886-025-02195-x
Iswaree D Balakrishnan, Neal K Lakdawala
{"title":"Contemporary Insights into LMNA Cardiomyopathy.","authors":"Iswaree D Balakrishnan, Neal K Lakdawala","doi":"10.1007/s11886-025-02195-x","DOIUrl":"https://doi.org/10.1007/s11886-025-02195-x","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review aims to explore how a diagnosis of LMNA-related cardiomyopathy (LMNA-CM) informs clinical management, focusing on the prevention and management of its complications, through practical clinical strategies.</p><p><strong>Recent findings: </strong>Longitudinal studies have enhanced our understanding of the natural history of LMNA-CM including its arrhythmic and non-arrhythmic complications. A LMNA specific ventricular arrhythmia risk prediction strategy has been integrated into clinical practice guidelines. Although less robust, observational studies are shaping gene-specific strategies for mitigating other complications including atrioventricular block, atrial fibrillation and cardiomyopathy, while novel therapies have been evaluated in clinical trials. LMNA-CM follows an aggressive yet generally stereotyped course. Early recognition of anticipated complications allows for more effective prevention and management in both symptomatic and asymptomatic patients.</p>","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"40"},"PeriodicalIF":3.1,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Evolving Features of Takotsubo Syndrome.
IF 3.1 3区 医学
Current Cardiology Reports Pub Date : 2025-01-24 DOI: 10.1007/s11886-024-02154-y
Marco Giuseppe Del Buono, Giulia La Vecchia, Rocco Antonio Montone, Paula Rodriguez-Miguelez, Antonio Maria Leone, Tommaso Sanna, Francesco Burzotta, Filippo Crea, Antonio Abbate
{"title":"The Evolving Features of Takotsubo Syndrome.","authors":"Marco Giuseppe Del Buono, Giulia La Vecchia, Rocco Antonio Montone, Paula Rodriguez-Miguelez, Antonio Maria Leone, Tommaso Sanna, Francesco Burzotta, Filippo Crea, Antonio Abbate","doi":"10.1007/s11886-024-02154-y","DOIUrl":"https://doi.org/10.1007/s11886-024-02154-y","url":null,"abstract":"<p><strong>Purpose of the review: </strong>Takotsubo syndrome (TTS) is a transient form of left ventricular dysfunction, typically affecting post-menopausal females, often preceded by emotional or physical stressful events that act as triggers. Initially believed to be a rare and benign condition for its reversible nature, TTS has recently emerged as a complex multifaceted clinical entity, with heterogenous clinical presentations and a non-negligible risk of serious in-hospital complications, including acute heart failure, arrhythmias and death.</p><p><strong>Recent findings: </strong>Emerging pathophysiological hypotheses, ranging from microvascular dysfunction to systemic inflammation, offer new insights into the underlying mechanisms of TTS. Moreover, increasing awareness of potential complications during the acute phase of the disease underscores its significant prognostic implications and emphasizes the need for randomized clinical trials to guide the therapeutic management of TTS. In this narrative review article, we aim to discuss the recent insights on the epidemiology, pathophysiology, treatment and prognosis of patients affected by TTS discussing the emerging evidence and the remaining knowledge gap in the field.</p>","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"39"},"PeriodicalIF":3.1,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Narrative Review of Cardiometabolic Profiles among U.S. Adults: Temporal Trends and Implications.
IF 3.1 3区 医学
Current Cardiology Reports Pub Date : 2025-01-23 DOI: 10.1007/s11886-024-02179-3
Junxiu Liu, Lei Hao, Carl J Lavie
{"title":"A Narrative Review of Cardiometabolic Profiles among U.S. Adults: Temporal Trends and Implications.","authors":"Junxiu Liu, Lei Hao, Carl J Lavie","doi":"10.1007/s11886-024-02179-3","DOIUrl":"https://doi.org/10.1007/s11886-024-02179-3","url":null,"abstract":"<p><strong>Purpose of review: </strong>To provide a narrative overview of trends and disparities in the cardiometabolic profiles of U.S. adults by synthesizing findings from nationally representative studies conducted between 1999 and 2020.</p><p><strong>Recent findings: </strong>During the study period, the cardiometabolic profiles of U.S. adults displayed a complex mix of trends. While there were notable improvements in specific risk factors, such as reductions in total cholesterol, triglycerides, and low-density lipoprotein cholesterol levels, other aspects of cardiometabolic health worsened. The mean body mass index and hemoglobin A1c levels increased, accompanied by significant rises in the prevalence of obesity, type 2 diabetes, and metabolic syndrome. Despite some progress in blood pressure and lipid profiles, the overall cardiometabolic health of the population declined, with only a small percentage of adults maintaining optimal health by 2018. Furthermore, significant disparities persisted across racial and socioeconomic groups, with non-Hispanic Black participants and those with lower education and income facing higher cardiometabolic risks compared to their counterparts. Despite improvements in certain aspects of cardiometabolic profiles among U.S. adults, significant challenges remain, particularly with the rising rates of obesity, type 2 diabetes, and metabolic syndrome. Persistent disparities in cardiometabolic health across sociodemographic groups emphasize the need for comprehensive public health strategies that address medical care, lifestyle factors, and social determinants of health. Future efforts should prioritize reducing these disparities and enhancing health equity to mitigate the overall burden of cardiometabolic disease.</p>","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"36"},"PeriodicalIF":3.1,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Accuracy of Technetium-99 m Pyrophosphate Imaging in Diagnosing Transthyretin Cardiac Amyloidosis and Its Impact on Patient Management.
IF 3.1 3区 医学
Current Cardiology Reports Pub Date : 2025-01-23 DOI: 10.1007/s11886-025-02202-1
Zainab Altaha, Robert J H Miller
{"title":"The Accuracy of Technetium-99 m Pyrophosphate Imaging in Diagnosing Transthyretin Cardiac Amyloidosis and Its Impact on Patient Management.","authors":"Zainab Altaha, Robert J H Miller","doi":"10.1007/s11886-025-02202-1","DOIUrl":"https://doi.org/10.1007/s11886-025-02202-1","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review evaluates recent advancements in Technetium-99 m pyrophosphate (99mTc-PYP) imaging for transthyretin amyloid cardiomyopathy (ATTR-CM). We summarize the advantages of single-photon emission computed tomography (SPECT) over planar imaging, the potential impact of quantitative methods, and emerging data for quantifying response to therapy.</p><p><strong>Recent findings: </strong>The current literature demonstrates the superior diagnostic accuracy of SPECT compared with planar imaging in 99mTc-PYP studies. Emerging quantitative methods, using hybrid SPECT/CT and artificial intelligence, show promise for enhancing diagnostic precision and risk assessment. Recent studies have also highlighted the potential of 99mTc-PYP quantification for monitoring treatment response. 99mTc-PYP SPECT imaging has exceptional diagnostic accuracy for ATTR-CM. Quantitative techniques, which can be facilitated by artificial intelligence, improve risk stratification and may aid in treatment monitoring. Future research should focus on clarifying the clinical role and optimal approach for quantification.</p>","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"37"},"PeriodicalIF":3.1,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eosinophilic Myocarditis: A Concise Review.
IF 3.1 3区 医学
Current Cardiology Reports Pub Date : 2025-01-23 DOI: 10.1007/s11886-024-02184-6
Ashlee M Asada, Rami Kahwash, Vincenzo Trovato
{"title":"Eosinophilic Myocarditis: A Concise Review.","authors":"Ashlee M Asada, Rami Kahwash, Vincenzo Trovato","doi":"10.1007/s11886-024-02184-6","DOIUrl":"10.1007/s11886-024-02184-6","url":null,"abstract":"<p><strong>Purpose of review: </strong>Eosinophilic myocarditis (EM) is a rare and heterogeneous form of inflammatory heart disease that can present with a wide range of severity. Current literature is limited to case reports or small case series that outline the evaluation process, disease course, and the nonstandardized treatments trialed. This review aims to concisely summarize the current literature on EM including an update on maintenance therapy for refractory or recurrent disease.</p><p><strong>Recent findings: </strong>In the last several years, several observational studies have reported the clinical benefit of mepolizumab and benralizumab in refractory EM. EM is a complex and heterogenous cause of inflammatory heart disease with a wide range of etiologies and presentations. Treatment of this disease has not been standardized as there are no large scale trials quantifying benefit of any specific therapy regimen. Targeted biologics show promise in observational studies; therefore, prospective studies are needed to quantify this benefit in EM.</p>","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"38"},"PeriodicalIF":3.1,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transthyretin Cardiac Amyloidosis: Current and Emerging Therapies. 转甲状腺素型心脏淀粉样变性:当前和新出现的治疗方法。
IF 3.1 3区 医学
Current Cardiology Reports Pub Date : 2025-01-22 DOI: 10.1007/s11886-024-02172-w
Aditi G M Patel, Pengyang Li, Narotham Badrish, Aditya Kesari, Keyur B Shah
{"title":"Transthyretin Cardiac Amyloidosis: Current and Emerging Therapies.","authors":"Aditi G M Patel, Pengyang Li, Narotham Badrish, Aditya Kesari, Keyur B Shah","doi":"10.1007/s11886-024-02172-w","DOIUrl":"10.1007/s11886-024-02172-w","url":null,"abstract":"<p><strong>Purpose of review: </strong>In this article, we describe current and newer TTR stabilizers, TTR silencers which include small interfering RNA agents (siRNA), antisense oligonucleotides (ASO) and CRISPR-Cas9 gene editing, and TTR depleters, which investigates the use of monoclonal antibodies to remove amyloid fibril deposits for patients with advanced disease.</p><p><strong>Recent findings: </strong>Once thought to be a rare and fatal condition, increased recognition, improved non-invasive diagnostic tools, and the explosive development of novel therapies, has transformed the landscape of transthyretin amyloid cardiomyopathy (ATTR-CM). Advances in cardiac imaging with respect to echocardiography, cardiac magnetic resonance imaging (CMR), and radionuclide bone scintigraphy has increased the diagnosis of ATTR-CM over the last twenty years. Ongoing clinical trials are evaluating several novel therapies at several mechanistic targets in the transthyretin (TTR) amyloidogenesis cascade, including the recently published findings from the study of vutrisiran, a siRNA agent. Our review provides a comprehensive summary of current and emerging therapies for ATTR-CM. While these are promising, disease-modifying treatments, reaching vulnerable populations early in the disease course should be a focus for future studies and interventions.</p>","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"33"},"PeriodicalIF":3.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11754378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Echocardiographic Updates in the Assessment of Cardiomyopathy. 超声心动图评价心肌病的最新进展。
IF 3.1 3区 医学
Current Cardiology Reports Pub Date : 2025-01-22 DOI: 10.1007/s11886-024-02159-7
Baoqiong Liu, Kandarp Suthar, Christine M Gerula
{"title":"Echocardiographic Updates in the Assessment of Cardiomyopathy.","authors":"Baoqiong Liu, Kandarp Suthar, Christine M Gerula","doi":"10.1007/s11886-024-02159-7","DOIUrl":"10.1007/s11886-024-02159-7","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review aims to provide an updated overview of the role of echocardiography in the assessment of cardiomyopathies, highlighting recent findings and technological advancements.</p><p><strong>Recent findings: </strong>Over the past few years, significant advancements in echocardiographic techniques have improved diagnostic accuracy and provided important prognostic value in the assessment of cardiomyopathies. Cardiomyopathy is a group of diseases affecting the heart muscle. Echocardiography, a non-invasive imaging modality provides crucial information on cardiac structure, function, and hemodynamics. Recent advancements, including strain imaging, speckle-tracking, and 3D echocardiography enhance the precision of structural and functional assessments, while artificial intelligence integration improves diagnostic accuracy and workflow efficiency. These advancements not only refine diagnostic capabilities but also provide prognostic insights and facilitate better patient outcomes.</p>","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"34"},"PeriodicalIF":3.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11754376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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