Current Cardiology Reports最新文献

In-Stent Restenosis: Incidence, Mechanisms, and Treatment Options. 支架内再狭窄：发生率、机制和治疗选择。

IF 3.1 3区医学

Current Cardiology Reports Pub Date : 2025-06-19 DOI: 10.1007/s11886-025-02249-0

Michael Sola, Zachary Tugaoen, Jessica Willis, George A Stouffer

{"title":"In-Stent Restenosis: Incidence, Mechanisms, and Treatment Options.","authors":"Michael Sola, Zachary Tugaoen, Jessica Willis, George A Stouffer","doi":"10.1007/s11886-025-02249-0","DOIUrl":"https://doi.org/10.1007/s11886-025-02249-0","url":null,"abstract":"Purpose of review: To provide an overview of up-to-date treatment practices for in-stent restenosis (ISR).Recent findings: ISR is treated with similar effectiveness by paclitaxel drug coated balloons and second-generation drug eluting stents. Sirolimus coated balloons are an emerging technology that requires further investigation. The management of ISR remains challenging even with the newest generation of drug-eluting stents. The use of intravascular imaging is highly recommended to identify the mechanisms of stent failure and to tailor the method of treatment, whether it is plain old balloon angioplasty, plaque/calcium modifying tools such as intravascular lithotripsy or rotational atherectomy, additional drug eluting stents, or drug coated balloons. Paclitaxel drug coated balloons are the most recent technological advancement which has provided an option to treat ISR that doesn't require further layers of metal. Currently, other drug coatings are being studied but it is unclear whether these balloons are as effective as paclitaxel coated balloons, with ongoing trials designed to answer this question.","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"96"},"PeriodicalIF":3.1,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiac Regeneration and Repair in Zebrafish and Mammalian Models. 斑马鱼和哺乳动物心脏再生和修复模型。

IF 3.1 3区医学

Current Cardiology Reports Pub Date : 2025-06-17 DOI: 10.1007/s11886-025-02235-6

Stanislao Igor Travisano, Ching-Ling Lien

{"title":"Cardiac Regeneration and Repair in Zebrafish and Mammalian Models.","authors":"Stanislao Igor Travisano, Ching-Ling Lien","doi":"10.1007/s11886-025-02235-6","DOIUrl":"https://doi.org/10.1007/s11886-025-02235-6","url":null,"abstract":"Aim: In this review, we discuss the regenerative processes in the heart, focusing on non-cardiomyocyte cell populations (fibroblasts, immune cells, and endothelial cells) in zebrafish and mammals. We highlight the role of signaling pathways in heart repair and the potential for therapeutic strategies based on these mechanisms.Purpose of review: The review examines key molecular and cellular mechanisms in cardiac regeneration, with a focus on fibroblasts, immune modulation, and endothelial function, to identify strategies for enhancing heart repair.Recent findings: Recent advancements in characterization of different cell types at the single cell level, along with the discovery of regeneration enhancer elements, have opened new avenues for cardiac regeneration. Targeting the epicardium, along with fibroblast activation, immune modulation, and endothelial signaling, may offer therapeutic strategies to enhance heart regeneration by supporting cardiomyocytes in mice and humans. While non-cardiomyocytes in zebrafish contribute to heart regeneration, in mice and humans, these cells often drive fibrosis instead. Understanding these species-specific differences is crucial for optimizing therapeutic approaches to treat cardiac injury and prevent fibrosis.","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"95"},"PeriodicalIF":3.1,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current Status of Cardiovascular Disease in Asian Americans: One Size Does Not Fit All. 亚裔美国人心血管疾病的现状：一种模式不适合所有人。

IF 3.1 3区医学

Current Cardiology Reports Pub Date : 2025-06-17 DOI: 10.1007/s11886-025-02245-4

Pristine Mei, Yamini S Levitzky, Susmita Parashar, Roopa A Rao, Lavanya Kondapalli, D Elizabeth Le

{"title":"Current Status of Cardiovascular Disease in Asian Americans: One Size Does Not Fit All.","authors":"Pristine Mei, Yamini S Levitzky, Susmita Parashar, Roopa A Rao, Lavanya Kondapalli, D Elizabeth Le","doi":"10.1007/s11886-025-02245-4","DOIUrl":"https://doi.org/10.1007/s11886-025-02245-4","url":null,"abstract":"Purpose of review: To provide an updated summary of knowledge about cardiovascular disease in Asian Americans living in the United States.Recent findings: Asian Americans living in the United States are a heterogenous and diverse group of individuals with variable coronary artery disease, heart failure, and stroke prevalence and risks and mortality rates. Compared to other Asian American subgroups, East Asians tend to have lower coronary artery disease risks, South Asians have high prevalence of traditional cardiovascular risks, particularly diabetes, and Southeast Asians have high rates of hypertension and age-adjusted stroke mortality death rate. Multiple studies have demonstrated disparities among various Asian Americans subgroups in cardiovascular disease, heart failure, and stroke risk. Valvular heart disease, arrhythmia, pharmacotherapy treatment, and procedural outcome data are limited. It is important to report disaggregated and sex-specific data in future clinical trials not only for racial groups but also for Asian American ethnic subgroups.","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"94"},"PeriodicalIF":3.1,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiovascular Care in Women Veterans: An Updated Profile. 女性退伍军人的心血管护理：最新概况

IF 3.1 3区医学

Current Cardiology Reports Pub Date : 2025-06-12 DOI: 10.1007/s11886-025-02247-2

Pristine Mei, Delia Cotiga, Ingy Mahana, Nimra Gilani, Michelle L Dew, Susmita Parashar, D Elizabeth Le

{"title":"Cardiovascular Care in Women Veterans: An Updated Profile.","authors":"Pristine Mei, Delia Cotiga, Ingy Mahana, Nimra Gilani, Michelle L Dew, Susmita Parashar, D Elizabeth Le","doi":"10.1007/s11886-025-02247-2","DOIUrl":"https://doi.org/10.1007/s11886-025-02247-2","url":null,"abstract":"Purpose of review: To provide an updated summary of the burden and care of cardiovascular disease in women veterans.Recent findings: Women veterans can develop atherosclerotic cardiovascular disease at a much earlier age of 30 years compared to non-veteran women. Those who experienced chronic stress and environmental exposures were more likely to develop early menopause and premature coronary artery disease. Despite major improvements in therapeutic options for cardiovascular disease, the mortality rate of women veterans continues to rise while that of their counterparts has steadily decreased. Women veterans is the fastest growing group of the veteran population. This is a unique and diverse population with a complex intersection of traditional, sex-specific, and military service-related risks for cardiovascular disease. They have a higher prevalence of both traditional and non-traditional risk factors compared to non-veteran women and are especially impacted by depression, post-traumatic stress syndrome, military sexual trauma, and housing instability.","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"93"},"PeriodicalIF":3.1,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychological Aspects of Wearable Health Technologies in Patients with Cardiovascular Disease: A Literature Review and Call to Action. 心血管疾病患者可穿戴健康技术的心理方面：文献综述和行动呼吁

IF 3.1 3区医学

Current Cardiology Reports Pub Date : 2025-06-06 DOI: 10.1007/s11886-025-02234-7

Allison E Gaffey, Stephanie A Hooker, Rachel Lampert, Anil K Gehi, Lindsey Rosman

{"title":"Psychological Aspects of Wearable Health Technologies in Patients with Cardiovascular Disease: A Literature Review and Call to Action.","authors":"Allison E Gaffey, Stephanie A Hooker, Rachel Lampert, Anil K Gehi, Lindsey Rosman","doi":"10.1007/s11886-025-02234-7","DOIUrl":"https://doi.org/10.1007/s11886-025-02234-7","url":null,"abstract":"Purpose of review: This review summarizes the psychological effects of consumer wearables in patients with established cardiovascular disease (CVD) and helps to identify remaining challenges that must be resolved to support the appropriate implementation of wearables.Recent findings: Consumer wearables (e.g., smartwatches, portable rhythm devices, rings, fitness bands, skin-surface patches) are increasingly used \"off label\" by patients and healthcare providers for ambulatory CVD monitoring and lifestyle modification. Emerging research suggests that while these technologies can motivate some patients to engage in healthy behaviors, they can also provoke adverse psychological reactions in others. Additionally, there are unintended, downstream consequences for clinicians and healthcare systems. Wearables show great promise for enhancing CVD management by providing patients and clinicians with continuous data on key health metrics that can be used for diagnostic and therapeutic purposes. Yet, the potential risks associated with their use must be acknowledged, rigorously investigated, and appropriately managed. Findings from this review emphasize the need for large, well-designed prospective studies and randomized trials to evaluate a broad range of wearable technologies and their influence on patients' mental health, quality of life, and CVD self-management over longer time periods and in high-risk groups (e.g., women, minorities, and children), and to determine their impact on patient outcomes, provider burden, healthcare utilization and costs. Addressing these challenges is crucial for fully integrating wearable health technologies into clinical practice.","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"92"},"PeriodicalIF":3.1,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144233470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multilevel Racism and Discrimination and Cardiovascular Disease and Related Biopsychosocial Mechanisms: An Integrated Scoping and Literature Review and Future Research Agenda. 多层次种族主义和歧视与心血管疾病及相关的生物心理社会机制：综合范围和文献综述及未来研究议程。

IF 3.1 3区医学

Current Cardiology Reports Pub Date : 2025-06-04 DOI: 10.1007/s11886-025-02238-3

Danielle L Beatty Moody, Elizabeth J Pantesco, Ayla Novruz, Nedelina Tchangalova, Richard C Sadler, Kellee White Whilby, Jason Ashe, Gilbert C Gee, LaBarron K Hill, Shari R Waldstein

{"title":"Multilevel Racism and Discrimination and Cardiovascular Disease and Related Biopsychosocial Mechanisms: An Integrated Scoping and Literature Review and Future Research Agenda.","authors":"Danielle L Beatty Moody, Elizabeth J Pantesco, Ayla Novruz, Nedelina Tchangalova, Richard C Sadler, Kellee White Whilby, Jason Ashe, Gilbert C Gee, LaBarron K Hill, Shari R Waldstein","doi":"10.1007/s11886-025-02238-3","DOIUrl":"10.1007/s11886-025-02238-3","url":null,"abstract":"Purpose of review: In the last two decades, empirical research has significantly advanced our understanding of the link between discrimination and cardiovascular disease (CVD). This integrated scoping and narrative literature review delineates the extant peer-reviewed research on discrimination and clinical and subclinical CVD in samples that include Black adults, using a multilevel conceptualization of race-related discrimination and racism. We also identify potential intermediary mechanisms in the racism-CVD relationship and propose a comprehensive future research agenda.Recent findings: Using the Population, Exposure and Outcome framework and PRISMA guidelines, we identified 37 empirical reports for inclusion drawn from 1900 to 2024. The bulk of the literature has focused on discrimination and racism that occurs at the interpersonal level (28 studies), while a smaller but growing body of work has examined cultural (5 studies) or institutional and structural-level racism and discrimination (4 studies) in relation to CVD risk. The majority of these studies show that greater exposure to discrimination or racism is associated with increased clinical or subclinical CVD risk. Potential pathways include societal, environmental, psychological, and biological factors; however, few studies have conducted formal tests of mediation. The literature suggests robust relations of multilevel racism and discrimination to manifestations of CVD across diverse exposure and outcome measures in Black adults. Our recommendations to eliminate cardiovascular health inequities in Black communities include enhancing academic scholarship training, securing targeted and protected funding, and adopting more robust methodological approaches.","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"91"},"PeriodicalIF":3.1,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12137394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interventional Management of Intracoronary Dissection/Hematoma: A Comprehensive Review. 冠状动脉内夹层/血肿的介入治疗：综合综述。

IF 3.1 3区医学

Current Cardiology Reports Pub Date : 2025-06-03 DOI: 10.1007/s11886-025-02237-4

Federico Giannino, Gabriele Carciotto, Francesco Pallante, Gabriele Monciino, Matteo Mancuso, Davide Raspanti, Giustina Iuvara, Manuela Ajello, Stefania Lo Giudice, Marcello Marchetta, Samuel La Cola, Maurizio Cusmà Piccione, Vittorio Virga, Antonio Micari, Giampiero Vizzari

{"title":"Interventional Management of Intracoronary Dissection/Hematoma: A Comprehensive Review.","authors":"Federico Giannino, Gabriele Carciotto, Francesco Pallante, Gabriele Monciino, Matteo Mancuso, Davide Raspanti, Giustina Iuvara, Manuela Ajello, Stefania Lo Giudice, Marcello Marchetta, Samuel La Cola, Maurizio Cusmà Piccione, Vittorio Virga, Antonio Micari, Giampiero Vizzari","doi":"10.1007/s11886-025-02237-4","DOIUrl":"https://doi.org/10.1007/s11886-025-02237-4","url":null,"abstract":"Purpose of review: Intracoronary dissection and hematoma are rare but significant causes of acute coronary syndromes (ACS), often leading to myocardial ischemia and infarction. Given their heterogeneous clinical presentation and the limited evidence on optimal management strategies, this review aims to evaluate current treatment approaches, including conservative, percutaneous, and surgical options, while highlighting emerging innovations and future research directions.Recent findings: Recent studies emphasize the role of advanced intracoronary imaging techniques, such as optical coherence tomography (OCT) and intravascular ultrasound (IVUS), in improving diagnostic accuracy and guiding therapeutic decisions. Conservative management is increasingly recognized as a viable option for stable patients, offering favorable long-term outcomes. Percutaneous coronary intervention (PCI) is indicated in cases with ongoing ischemia, hemodynamic instability, or high-risk anatomical features, though it carries risks such as dissection propagation and coronary rupture. Surgical intervention remains essential in cases of failed PCI or left main stem involvement, demonstrating high survival rates despite procedural challenges. Tailored therapeutic strategies, informed by patient-specific factors and intracoronary imaging, are crucial for optimizing outcomes in intracoronary dissection and hematoma. While conservative management is effective in selected cases, PCI and surgical interventions remain vital for high-risk patients. Future research should focus on refining risk stratification tools, improving imaging modalities, and developing standardized treatment algorithms to enhance patient care and clinical outcomes.","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"90"},"PeriodicalIF":3.1,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of Cardio-Renal-Metabolic Profile in Dilated Cardiomyopathy. 心肾代谢谱对扩张型心肌病的影响。

IF 3.1 3区医学

Current Cardiology Reports Pub Date : 2025-05-23 DOI: 10.1007/s11886-025-02241-8

Tamim Akbari, Daniel J Hammersley, Clarice Yau-Yee May, Brian P Halliday, Sanjay K Prasad

引用次数: 0

Polygenic Risk Scores in Dilated Cardiomyopathy: Towards the Future. 扩张型心肌病的多基因风险评分：走向未来。

IF 3.1 3区医学

Current Cardiology Reports Pub Date : 2025-05-14 DOI: 10.1007/s11886-025-02239-2

Daria R Kramarenko, Sean J Jurgens, Yigal M Pinto, Connie R Bezzina, Ahmad S Amin

{"title":"Polygenic Risk Scores in Dilated Cardiomyopathy: Towards the Future.","authors":"Daria R Kramarenko, Sean J Jurgens, Yigal M Pinto, Connie R Bezzina, Ahmad S Amin","doi":"10.1007/s11886-025-02239-2","DOIUrl":"https://doi.org/10.1007/s11886-025-02239-2","url":null,"abstract":"Purpose of review: Genome-wide association studies (GWASs) have recently shown that common genetic variations significantly affect the risk of developing dilated cardiomyopathy (DCM). This has enabled the development of polygenic scores (PGSs), which aim to aggregate the impact of multiple common genetic variants across the genome to provide an overall genetic risk score for disease manifestation and disease severity. In this review, we discuss the latest findings pertaining to GWASs and PGSs for DCM and various ways in which PGSs could improve the management of patients with DCM or risk of developing DCM.Recent findings: In 2024 the two largest GWAS meta-analyses for DCM were published. Notably, both studies produced PGSs that were able to discriminate healthy subjects from DCM patients which brings promise for potential clinical application of the scores. Large-scale GWAS have identified common genetic variants associated with DCM, leading to the development of PGS, which show strong associations with disease risk and hold potential for clinical applications. However, before clinical implementation, further research is needed to explore their utility in real-world settings and across diverse populations.","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"87"},"PeriodicalIF":3.1,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12078399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reproducibility of ¹⁸F-Sodium Fluoride Positron Emission Tomography for Assessing Microcalcification in Coronary Arterial and Thoracic Aortic Atherosclerosis: Is the Signal below the Resolution of PET? 18f -氟化钠正电子发射断层扫描评估冠状动脉和胸主动脉粥样硬化微钙化的再现性：信号是否低于PET分辨率？

IF 3.1 3区医学

Current Cardiology Reports Pub Date : 2025-05-14 DOI: 10.1007/s11886-025-02240-9

Ondrej Fanta, Shiv Patil, Thomas Werner, Drew A Torigian, Abass Alavi

{"title":"Reproducibility of 18F-Sodium Fluoride Positron Emission Tomography for Assessing Microcalcification in Coronary Arterial and Thoracic Aortic Atherosclerosis: Is the Signal below the Resolution of PET?","authors":"Ondrej Fanta, Shiv Patil, Thomas Werner, Drew A Torigian, Abass Alavi","doi":"10.1007/s11886-025-02240-9","DOIUrl":"https://doi.org/10.1007/s11886-025-02240-9","url":null,"abstract":"Purpose of review: The rising prevalence of atherosclerosis has prompted the development of novel diagnostic methods capable of identifying early-stage disease when therapeutic interventions may be most effective. 18F-sodium fluoride (NaF) positron emission tomography/computed tomography (PET/CT) is a molecular imaging technique that can quantify subclinical microcalcification in arterial plaque. The focus of this review article is to discuss the utility of 18F-NaF PET/CT in assessing atherosclerotic disease of major susceptible blood vessels, particularly the coronary arteries and thoracic aorta.Recent findings: 18F-NaF uptake observed on PET imaging demonstrates promising potential as a marker of atherosclerotic burden in individual coronary arteries, whole heart segmentations, and the thoracic aorta. Global versus focal assessment of 18F-NaF uptake in small arteries is a significant source of methodological heterogeneity among studies. The accuracy and reproducibility of 18F-NaF PET/CT may be improved by standardized quantification methods in light of the limited spatial resolution of PET, particularly through the use of techniques to evaluate global atherosclerotic burden.","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"88"},"PeriodicalIF":3.1,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12078425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0