Current NanosciencePub Date : 2023-10-05DOI: 10.2174/0115734137252527230919110809
Himanshu Chaudhrya, Naresh K. Rangraa, Pooja A. Chawlaa
{"title":"Synthetic Strategies for Vitamin-loaded Carbon Dots and their Detection using Biosensors: A Review","authors":"Himanshu Chaudhrya, Naresh K. Rangraa, Pooja A. Chawlaa","doi":"10.2174/0115734137252527230919110809","DOIUrl":"https://doi.org/10.2174/0115734137252527230919110809","url":null,"abstract":"Abstract: Carbon dots belong to the class of nanomaterials invented accidentally and are attracting a lot of attention these days. Carbon dots are non-toxic, photostable, and easy-to-synthesize nano formulations having good water-soluble properties when treated chemically by manipulating surface active groups, followed by the addition of solubilizing agents and size reduction. These are widely used in bioimaging, electrochemical sensing, targeted drug delivery, and other biomedical activities. In recent years, significant attempts have been emphasized by analysts to the detection of vitamins embedded carbon dots using biosensors. The biosensing of vitamins has become easy due to the luminescence property of carbon dots, which makes them easy to detect. Therefore, in this review, we have reported synthetic strategies and recent biosensorbased detection techniques used in the analysis of vitamin-loaded carbon dots. Even from the carbon dot’s analytical perspective, there is still a lot of research needed in the area of biosensing, bioimaging, and healthcare applications. Unique features, along with the controllable synthesis methods, will lead to a bright future in the detection and characterization of drugs using carbon dots.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135546667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-10-04DOI: 10.2174/0115734137268768230919170012
S. Sreejith, J. Ajayan, N.V. Uma Reddy, Manikandan M., Radhika J.M
{"title":"A Critical Review on Various Buffer Layers used to Enhance the Photovoltaic Performance of Organic Solar Cells","authors":"S. Sreejith, J. Ajayan, N.V. Uma Reddy, Manikandan M., Radhika J.M","doi":"10.2174/0115734137268768230919170012","DOIUrl":"https://doi.org/10.2174/0115734137268768230919170012","url":null,"abstract":"Abstract: Due to the high need for sustainable energy sources, there has been a tremendous increase in SC (solar cell) production and research in recent years. Despite the fact that inorganic SC has led the SC consumer market due to its exceptional efficiency, its expensive and difficult manufacture method makes it unaffordable. Hence alternative technology for SC has been explored by researchers to overcome the draw backs of inorganic SC fabrication. OSC (organic solar cell) alternatively known as polymer SC has the advantage of having lightweight, low production cost, and simple device structure. During the last few years, significant attention has been given in order to overcome the material and technological barriers in OSC devices to make them commercially viable. Buffer layers play a significant part in improving the power conversion efficiencies in OSCs, thus it is necessary to comprehend the underlying microscopic mechanisms that underlie the advancements in order to support the current qualitative knowledge. In this review article, we have studied extensively the impact of different BLs (buffer-layer) in enhancing the PCE (power conversion efficiency) and absorption capabilities of OSCs.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":"199 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-10-03DOI: 10.2174/0115734137259719230921065320
Qiang Wan, Rong Li, Meiping Ren, Gang Ke
{"title":"Hydrothermally Synthesized Boletus Brucella-derived Carbon Quantum Dots as a Fluorescent Probe for the Detection of Vitamin B2","authors":"Qiang Wan, Rong Li, Meiping Ren, Gang Ke","doi":"10.2174/0115734137259719230921065320","DOIUrl":"https://doi.org/10.2174/0115734137259719230921065320","url":null,"abstract":"Background:: In the paper, Boletus Brucella was used as carbon source material to prepare carbon dots (CDs) by one-step hydrothermal method. The CDs had high quantum yield and high photostability. Methods:: A range of characterization studies were conducted on CDs, and the results showed that the average particle size of CDs was 5 nm, emitting blue fluorescence. The optimal excitation wavelength was 337 nm, and the emission wavelength was 440 nm. Results:: Based on the static quenching, the fluorescence of CDs could be effectively quenched by VB2. Therefore, a highly sensitive and selective fluorescent probe for detecting VB2 was constructed. The CDs were successfully used to detect tablets, human blood, and urine. Conclusion:: The recovery rate of VB2 was 97.55~99.45%, and the relative standard deviation was 1.29~3.76 (n=3). conclusion: The recovery rate of VB2 was 97.55~99.45%, and the relative standard deviation was 1.29~3.76 (n=3).","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135789236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-09-15DOI: 10.2174/1573413719666230915103459
Ke Xu, Bingge Wang
{"title":"Study on Measurement Method of Three-dimensional Position of Unlabeled Microspheres under Bright Background","authors":"Ke Xu, Bingge Wang","doi":"10.2174/1573413719666230915103459","DOIUrl":"https://doi.org/10.2174/1573413719666230915103459","url":null,"abstract":"Abstract: Using computer vision technology to obtain the position and trajectory data of particle probe microspheres from microscope images has significance and value in the molecular field. However, most of the existing microsphere measurement methods are based on transmission, which can only be measured under transparent samples and substrates and are not suitable for the application scenario of living cell measurement. In this paper, a method based on reflectivity imaging is proposed to measure the three-dimensional position of the dark microspheres in the bright field. Based on the outermost ring radius method, the relationship between the inner ring radius of the microsphere spot and the out-of-focus distance was explored to measure the coordinates in the Z direction. Cardiomyocytes were combined with 10um size silica microspheres. Experiments show that in a bright field with a high perturbation environment, it can achieve high precision measurement of dark microspheres and achieve three-dimensional position measurement with an accuracy of 50nm in XY direction and 100nm in Z direction.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135485374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-09-01DOI: 10.2174/1573413718666220607164053
Khaled Alkhuder
{"title":"Surface-Enhanced Raman Scattering: A Promising Nanotechnology for Anti-Counterfeiting and Tracking Systems","authors":"Khaled Alkhuder","doi":"10.2174/1573413718666220607164053","DOIUrl":"https://doi.org/10.2174/1573413718666220607164053","url":null,"abstract":"Abstract: Surface-enhanced Raman Scattering (SERS) is a sensing method based on inelastic scattering of a laser beam by a reporter molecule absorbed on a plasmonic substrate. The incident laser beam induces a localized-surface plasmon resonance in the substrate, which generates an oscillating electromagnetic field on the substrate dielectric surface. Under the influence of this field, the reporter molecule absorbed on the plasmonic substrate starts to vibrate, causing inelastic scattering of the laser beam. The laser-induced electromagnetic field is also the main contributor to the enhancement observed in the intensity of the scattered light. Plasmonic substrates are nanostructured surfaces often made of noble metals. The surface enhancement of a plasmonic substrate is determined primarily by factors related to the substrate’s nano-architecture and its composition. SERS-based labeling has emerged as a reliable and sophisticated anti-counterfeiting technology with potential applications in a wide range of industries. This technology is based on detecting the SERS signals produced by SERS tags using Raman spectroscopy. SERS tags are generally made of a plasmonic substrate, a Raman reporter, and a protective coating shell. They can be engineered using a wide variety of materials and methods. Several SERS-based anticounterfeiting labels have been developed in the past two decades. Some of these labels have been successfully combined with identification systems based on artificial intelligence. The purpose of this review is to shed light on the SERS technology and the progress that has been achieved in the SERS-based tracking systems.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135685709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-08-31DOI: 10.2174/1573413719666230831152658
Sarwin Yaseen Hussein, Tariq Abdul Hameed Abbas
{"title":"Synthesis and antibacterial activity of ultrasmall silver nanoparticles by pulsed laser ablation in deionized water","authors":"Sarwin Yaseen Hussein, Tariq Abdul Hameed Abbas","doi":"10.2174/1573413719666230831152658","DOIUrl":"https://doi.org/10.2174/1573413719666230831152658","url":null,"abstract":"Background: The main objective of this work is the synthesis and evaluation of silver nanoparticles (Ag NPs) by using pulsed laser ablation of a silver (Ag) target in deionized water and examining their antibacterial activity. Methods: Colloidal solutions of silver nanoparticles were prepared with different pulsed laser energies (620, 880, and 1000) mJ of wavelength 1064 nm and frequency 10 Hz. To determine their structure, optical, morphology, elemental composition, and infrared spectra, the synthesized Ag NPs were characterized using various high-throughput analytical techniques such as (UV-Vis) spectroscopy, transmission electron microgram (TEM), electron dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR) spectra, and Zeta potential. Results: The results show that the properties of synthesized Ag NPs depend much more on the laser energy. The laser energy can be used to control the properties of the prepared nanoparticles. Uniform distributions of spherical ultrasmall Ag NPs with an average size of (3) nm were obtained suspended in deionized water, which is the most effective size for antibacterial activity. However, the result indicated that the ablated Ag NPs were stable for 4 months in deionized water. The antibacterial activity of the colloidal solution of synthesized Ag NPs against Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus aureus (S. aureus) bacteria was then examined using the agar-well diffusion method. Conclusion: It was found that the prepared nanoparticles exhibited strong activity against E. coli and S. aureus bacteria growth. The average zones of inhibition of Ag NPs were found to be about (26) m¬¬¬¬¬¬m for E. coli and (32) mm for S. aureus bacteria.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135890524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-08-29DOI: 10.2174/1573413719666230829142724
Ke Xu, Wei Zheng
{"title":"Fabrication of graphene-based ammonia sensors: a review","authors":"Ke Xu, Wei Zheng","doi":"10.2174/1573413719666230829142724","DOIUrl":"https://doi.org/10.2174/1573413719666230829142724","url":null,"abstract":"\u0000\u0000Graphene gas sensors have gained much scientific interest due to their high sensitivity, selectivity, and fast detection of various gases. This article summarizes the research progress of graphene gas sensors for detecting ammonia gas at room temperature. Firstly, the performance and development trends of the graphene/semiconductor Schottky diode sensor are discussed. Secondly, manufacturing methods and the latest developments in graphene field-effect transistor sensors are reviewed. Finally, the basic challenges and latest efforts of functional ammonia gas sensors are studied. The discussion delves into each sensor type's detection principles and performance indicators, including selectivity, stability, measurement range, response time, recovery time, and relative humidity. A comparative analysis is conducted to highlight the progress achieved in research, elucidating the advantages, disadvantages, and potential solutions associated with various sensors. As a result, the paper concludes by exploring the future development prospects of graphene-based ammonia sensors.\u0000","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44470554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-07-20DOI: 10.2174/1573413719666230720161905
W. Nabgan, V. Adimule, Parashuram Laxminarayana, Kalpana Sharma, Nidhi Manhas
{"title":"Synthesis and Characterization of Carbon Nano Sphere-doped Gd: Alpha Sb2O4Nanostructure for High-Performance Energy Storage Applications","authors":"W. Nabgan, V. Adimule, Parashuram Laxminarayana, Kalpana Sharma, Nidhi Manhas","doi":"10.2174/1573413719666230720161905","DOIUrl":"https://doi.org/10.2174/1573413719666230720161905","url":null,"abstract":"\u0000\u0000To enhance the super capacitive properties of nanocomposites, the effective method is to combine carbon nanospheres with mesoporous structures with Gd3+:α-Sb2O4 inorganic nanocomposites (NC) to form hybrid electrodes. An as-prepared hybrid electrode material possesses increased energy density, high rate of reversibility and cyclic stability when incorporated in electrochemical cyclic voltammetric studies.\u0000\u0000\u0000\u0000In the present investigation, various wt % of C-nanospheres (Cx) (5 %, 10% and 20%) were decorated over Gd3+: α-Sb2O4 nanocomposites and were synthesized by coprecipitation method. XRD, SEM, EDX, UV-visible, and XPS are only a few of the analytical techniques used to describe the as-prepared hybrid nanocomposites. Electrochemical cyclic voltammetry was carried out in a 6M KOH solution, three-electrode system.\u0000\u0000\u0000\u0000The crystal structure and morphology of Cx: Gd3+@ α-Sb2O4 NC showed a mixed hexagonal phase and agglomerated tiny irregularly shaped morphology that appeared as the Cx concentration increased. Redshift in optical absorption peak appeared (near UV-edge), and the optical band gap (Eg) value increased from 3.53 eV to 3.65 eV. The electrochemical supercapacitor showed the highest specific capacitance of 989 F/g at the current density of 1 A/g for C20%:Gd3+@α-Sb2O4 NC compared with Cx:Gd3+@α-Sb2O4 (x = 5 % and 10 %) and undoped Gd3+:α-Sb2O4 NC. The change in phase angle and Rs value of 1.98 was attributed to the ideal supercapacitor properties. The cyclic stability after 5000 cycles with 79.71 % capacitive retention was exhibited by C20%:Gd3+@α-Sb2O4 NC.\u0000\u0000\u0000\u0000The present research introduces ease of synthesis of hybrid electrode materials possessing high active surface area, increased energy density, high cyclic stability, and reversibility in an aqueous solution.\u0000","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43375860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-07-18DOI: 10.2174/1573413719666230718122527
Feng He, Lei Zhang, Jingyi Lin, Can Zhang, Sijing Hu, Yang Dong, Guanwei Fan
{"title":"Recent advances in the nanotechnology-based applications of essential oils","authors":"Feng He, Lei Zhang, Jingyi Lin, Can Zhang, Sijing Hu, Yang Dong, Guanwei Fan","doi":"10.2174/1573413719666230718122527","DOIUrl":"https://doi.org/10.2174/1573413719666230718122527","url":null,"abstract":"\u0000\u0000Essential oils (EOs), which are volatile aromatic substances extracted from plants, exhibit antibacterial, antitumor, antiviral, antioxidant, anti-inflammatory, and other effects. Eos are widely used in different fields because of their various biological activities. EOs are volatile and insoluble in water, so their effective utilization rate is greatly reduced. In this regard, researchers propose to use nanotechnology to construct an EOs nanosystem to solve the application problems and improve the utilization rate of EOs. This review summarizes the latest research progress and application status of EOs nanocapsules, EOs nanoemulsion, EOs nanofiber membrane, EOs nanoparticles and EOs nanoliposome, including the methodologies, characteristics and applications.Analyzes the advantages and disadvantages of existing EOs nanotechnology and provides an outlook for future development.\u0000","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41735769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-07-17DOI: 10.2174/1573413719666230717123734
R. Malviya, Rishav Sharma
{"title":"Virus-like Particles for Disease Diagnosis and Drug Delivery Applications","authors":"R. Malviya, Rishav Sharma","doi":"10.2174/1573413719666230717123734","DOIUrl":"https://doi.org/10.2174/1573413719666230717123734","url":null,"abstract":"\u0000\u0000Virus-like particles (VLPs) are nanoscale, self-assembling cage structures made out of proteins with practical uses in biomedicine. They might be used to create better vaccinations, imaging equipment, gene and drug therapy delivery systems, and in vitro diagnostic equipment. VLPs are nanostructures that might be used in medicine, immunization, and diagnostics, among other areas. Many VLPs-based vaccines are now in use for the treatment of infectious diseases, and many more are on their way to clinical testing thanks to recent advancements in biomedical engineering. Although VLPs exhibit promising qualities in terms of efficacy, safety, and diversity, they may become more widely used in the future. Vaccines based on virus-like particles (VLPs) might serve as an effective addition to current immunization strategies for the prevention and treatment of emerging infectious diseases. The growing field of healthcare prevention has become increasingly interested in VLPs, leading to the discovery of various VLP-based candidate vaccines for vaccination towards a wide range of infectious pathogens, one of the most recent that has been developed is the vaccine against SARS-CoV-2, the effectiveness of that is now being tested. VLPs can elicit both antibody and cell-mediated immune responses, unlike standard inactivated viral vaccines. However, several problems persist with this surface display method and will need fixing in the future. VLPs-based medicinal delivery, nanoreactors for treatment, and imaging systems are being developed with promising results. The latest developments in the generation and fabrication of VLPs involve explorations of several expression systems for their creation and their application as vaccines for the avoidance of infectious diseases and malignancies. This manuscript offers the most advanced perspective on biomedical applications based on VLPs, as well as details innovative methods for manufacturing, functionalization, and delivery of VLPs.\u0000","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41385212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}