Current NanosciencePub Date : 2023-08-31DOI: 10.2174/1573413719666230831152658
Sarwin Yaseen Hussein, Tariq Abdul Hameed Abbas
{"title":"Synthesis and antibacterial activity of ultrasmall silver nanoparticles by pulsed laser ablation in deionized water","authors":"Sarwin Yaseen Hussein, Tariq Abdul Hameed Abbas","doi":"10.2174/1573413719666230831152658","DOIUrl":"https://doi.org/10.2174/1573413719666230831152658","url":null,"abstract":"Background: The main objective of this work is the synthesis and evaluation of silver nanoparticles (Ag NPs) by using pulsed laser ablation of a silver (Ag) target in deionized water and examining their antibacterial activity. Methods: Colloidal solutions of silver nanoparticles were prepared with different pulsed laser energies (620, 880, and 1000) mJ of wavelength 1064 nm and frequency 10 Hz. To determine their structure, optical, morphology, elemental composition, and infrared spectra, the synthesized Ag NPs were characterized using various high-throughput analytical techniques such as (UV-Vis) spectroscopy, transmission electron microgram (TEM), electron dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR) spectra, and Zeta potential. Results: The results show that the properties of synthesized Ag NPs depend much more on the laser energy. The laser energy can be used to control the properties of the prepared nanoparticles. Uniform distributions of spherical ultrasmall Ag NPs with an average size of (3) nm were obtained suspended in deionized water, which is the most effective size for antibacterial activity. However, the result indicated that the ablated Ag NPs were stable for 4 months in deionized water. The antibacterial activity of the colloidal solution of synthesized Ag NPs against Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus aureus (S. aureus) bacteria was then examined using the agar-well diffusion method. Conclusion: It was found that the prepared nanoparticles exhibited strong activity against E. coli and S. aureus bacteria growth. The average zones of inhibition of Ag NPs were found to be about (26) m¬¬¬¬¬¬m for E. coli and (32) mm for S. aureus bacteria.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135890524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-08-29DOI: 10.2174/1573413719666230829142724
Ke Xu, Wei Zheng
{"title":"Fabrication of graphene-based ammonia sensors: a review","authors":"Ke Xu, Wei Zheng","doi":"10.2174/1573413719666230829142724","DOIUrl":"https://doi.org/10.2174/1573413719666230829142724","url":null,"abstract":"\u0000\u0000Graphene gas sensors have gained much scientific interest due to their high sensitivity, selectivity, and fast detection of various gases. This article summarizes the research progress of graphene gas sensors for detecting ammonia gas at room temperature. Firstly, the performance and development trends of the graphene/semiconductor Schottky diode sensor are discussed. Secondly, manufacturing methods and the latest developments in graphene field-effect transistor sensors are reviewed. Finally, the basic challenges and latest efforts of functional ammonia gas sensors are studied. The discussion delves into each sensor type's detection principles and performance indicators, including selectivity, stability, measurement range, response time, recovery time, and relative humidity. A comparative analysis is conducted to highlight the progress achieved in research, elucidating the advantages, disadvantages, and potential solutions associated with various sensors. As a result, the paper concludes by exploring the future development prospects of graphene-based ammonia sensors.\u0000","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44470554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-07-20DOI: 10.2174/1573413719666230720161905
W. Nabgan, V. Adimule, Parashuram Laxminarayana, Kalpana Sharma, Nidhi Manhas
{"title":"Synthesis and Characterization of Carbon Nano Sphere-doped Gd: Alpha Sb2O4Nanostructure for High-Performance Energy Storage Applications","authors":"W. Nabgan, V. Adimule, Parashuram Laxminarayana, Kalpana Sharma, Nidhi Manhas","doi":"10.2174/1573413719666230720161905","DOIUrl":"https://doi.org/10.2174/1573413719666230720161905","url":null,"abstract":"\u0000\u0000To enhance the super capacitive properties of nanocomposites, the effective method is to combine carbon nanospheres with mesoporous structures with Gd3+:α-Sb2O4 inorganic nanocomposites (NC) to form hybrid electrodes. An as-prepared hybrid electrode material possesses increased energy density, high rate of reversibility and cyclic stability when incorporated in electrochemical cyclic voltammetric studies.\u0000\u0000\u0000\u0000In the present investigation, various wt % of C-nanospheres (Cx) (5 %, 10% and 20%) were decorated over Gd3+: α-Sb2O4 nanocomposites and were synthesized by coprecipitation method. XRD, SEM, EDX, UV-visible, and XPS are only a few of the analytical techniques used to describe the as-prepared hybrid nanocomposites. Electrochemical cyclic voltammetry was carried out in a 6M KOH solution, three-electrode system.\u0000\u0000\u0000\u0000The crystal structure and morphology of Cx: Gd3+@ α-Sb2O4 NC showed a mixed hexagonal phase and agglomerated tiny irregularly shaped morphology that appeared as the Cx concentration increased. Redshift in optical absorption peak appeared (near UV-edge), and the optical band gap (Eg) value increased from 3.53 eV to 3.65 eV. The electrochemical supercapacitor showed the highest specific capacitance of 989 F/g at the current density of 1 A/g for C20%:Gd3+@α-Sb2O4 NC compared with Cx:Gd3+@α-Sb2O4 (x = 5 % and 10 %) and undoped Gd3+:α-Sb2O4 NC. The change in phase angle and Rs value of 1.98 was attributed to the ideal supercapacitor properties. The cyclic stability after 5000 cycles with 79.71 % capacitive retention was exhibited by C20%:Gd3+@α-Sb2O4 NC.\u0000\u0000\u0000\u0000The present research introduces ease of synthesis of hybrid electrode materials possessing high active surface area, increased energy density, high cyclic stability, and reversibility in an aqueous solution.\u0000","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43375860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-07-18DOI: 10.2174/1573413719666230718122527
Feng He, Lei Zhang, Jingyi Lin, Can Zhang, Sijing Hu, Yang Dong, Guanwei Fan
{"title":"Recent advances in the nanotechnology-based applications of essential oils","authors":"Feng He, Lei Zhang, Jingyi Lin, Can Zhang, Sijing Hu, Yang Dong, Guanwei Fan","doi":"10.2174/1573413719666230718122527","DOIUrl":"https://doi.org/10.2174/1573413719666230718122527","url":null,"abstract":"\u0000\u0000Essential oils (EOs), which are volatile aromatic substances extracted from plants, exhibit antibacterial, antitumor, antiviral, antioxidant, anti-inflammatory, and other effects. Eos are widely used in different fields because of their various biological activities. EOs are volatile and insoluble in water, so their effective utilization rate is greatly reduced. In this regard, researchers propose to use nanotechnology to construct an EOs nanosystem to solve the application problems and improve the utilization rate of EOs. This review summarizes the latest research progress and application status of EOs nanocapsules, EOs nanoemulsion, EOs nanofiber membrane, EOs nanoparticles and EOs nanoliposome, including the methodologies, characteristics and applications.Analyzes the advantages and disadvantages of existing EOs nanotechnology and provides an outlook for future development.\u0000","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41735769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-07-17DOI: 10.2174/1573413719666230717123734
R. Malviya, Rishav Sharma
{"title":"Virus-like Particles for Disease Diagnosis and Drug Delivery Applications","authors":"R. Malviya, Rishav Sharma","doi":"10.2174/1573413719666230717123734","DOIUrl":"https://doi.org/10.2174/1573413719666230717123734","url":null,"abstract":"\u0000\u0000Virus-like particles (VLPs) are nanoscale, self-assembling cage structures made out of proteins with practical uses in biomedicine. They might be used to create better vaccinations, imaging equipment, gene and drug therapy delivery systems, and in vitro diagnostic equipment. VLPs are nanostructures that might be used in medicine, immunization, and diagnostics, among other areas. Many VLPs-based vaccines are now in use for the treatment of infectious diseases, and many more are on their way to clinical testing thanks to recent advancements in biomedical engineering. Although VLPs exhibit promising qualities in terms of efficacy, safety, and diversity, they may become more widely used in the future. Vaccines based on virus-like particles (VLPs) might serve as an effective addition to current immunization strategies for the prevention and treatment of emerging infectious diseases. The growing field of healthcare prevention has become increasingly interested in VLPs, leading to the discovery of various VLP-based candidate vaccines for vaccination towards a wide range of infectious pathogens, one of the most recent that has been developed is the vaccine against SARS-CoV-2, the effectiveness of that is now being tested. VLPs can elicit both antibody and cell-mediated immune responses, unlike standard inactivated viral vaccines. However, several problems persist with this surface display method and will need fixing in the future. VLPs-based medicinal delivery, nanoreactors for treatment, and imaging systems are being developed with promising results. The latest developments in the generation and fabrication of VLPs involve explorations of several expression systems for their creation and their application as vaccines for the avoidance of infectious diseases and malignancies. This manuscript offers the most advanced perspective on biomedical applications based on VLPs, as well as details innovative methods for manufacturing, functionalization, and delivery of VLPs.\u0000","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41385212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-07-14DOI: 10.2174/1573413719666230714121859
A. Prabhakar, Deepti Verma, Nimisha Roy, Abhipsha Khadanga, Amar Dhwaj
{"title":"The Role Of Biosensors In Detection Of SARS-Cov-2: State-Of-The-Art And Future Prospects","authors":"A. Prabhakar, Deepti Verma, Nimisha Roy, Abhipsha Khadanga, Amar Dhwaj","doi":"10.2174/1573413719666230714121859","DOIUrl":"https://doi.org/10.2174/1573413719666230714121859","url":null,"abstract":"\u0000\u0000The world is fighting a pandemic so grave that perhaps it has never been witnessed before; COVID-19 is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As of August 31st, 2022, the WHO declared the total number of confirmed cases was 599,825,400, with 6,469,458 confirmed deaths from 223 countries under the scourge of this deadly virus. The SARS-CoV-2 is a β-coronavirus, which is an enveloped non-segmented positive-sense RNA virus. It is a close relative of the SARS and MERS viruses and has probably entered humans through bats. Human-to-human transmission is very rapid. People in contact with the patient or even the carriers became infected, leading to a widespread chain of contamination. We are presenting a mini-review on the role of biosensors in detecting SARS-CoV-2. Biosensors have been used for a very long time for viral detection and can be utilized for the prompt detection of the novel coronavirus. This article aims to provide a mini-review on the application of biosensors for the detection of the novel coronavirus with a focus on cost-effective paper-based sensors, nanobiosensors, Field effect transistors (FETs), and lab-on-chip integrated platforms.\u0000","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47780617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-06-08DOI: 10.2174/1573413719666230608112014
A. Tavakoli, Malihe Hamidzade, Saeed Motlaghzadeh, P. Khales, Danesh Aminpanah, S. Minaeian, S. M. Hosseini-Hosseinabad
{"title":"Metal and Metal Oxide Nanoparticles as Agents Against Human Infectious Viruses","authors":"A. Tavakoli, Malihe Hamidzade, Saeed Motlaghzadeh, P. Khales, Danesh Aminpanah, S. Minaeian, S. M. Hosseini-Hosseinabad","doi":"10.2174/1573413719666230608112014","DOIUrl":"https://doi.org/10.2174/1573413719666230608112014","url":null,"abstract":"\u0000\u0000Viral infections remain to be a serious threat to public health on a global scale. Recent outbreaks of viral infections have highlighted the urgent need for novel antiviral treatments. The recent development of metal/metal oxide nanoparticles for the treatment of various pathogenic viruses has received significant attention. There are established mechanisms of action for metal/metal oxide nanoparticles that can occur inside and outside host cells. These mechanisms include the interaction of nanoparticles with viral receptors, interference with viral attachment, interaction with the viral genome, inactivating virus particles prior to cellular entry, and interaction with viral replication factors. In this article, we attempted to present a comprehensive review of all published research on using metal/metal oxide nanoparticles against human infectious diseases and their antiviral modes of action.\u0000","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42498264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-06-05DOI: 10.2174/1573413719666230605120659
Smita D More, Anjali S Wadhokar, Rushali S Bedjawalge
{"title":"A Review on Solid Lipid Nanoparticles as Nano Drug Delivery Transporters","authors":"Smita D More, Anjali S Wadhokar, Rushali S Bedjawalge","doi":"10.2174/1573413719666230605120659","DOIUrl":"https://doi.org/10.2174/1573413719666230605120659","url":null,"abstract":"\u0000\u0000Solid lipid nanoparticles (SLN) have several potential uses in research for medicine such as drug discovery and drug delivery, an area at the forefront of evolving area of nanobiotechnology. In general, SLNs were created to address the drawbacks of conventional colloidal carriers, including emulsions, liposomes, and polymeric nanoparticles since they provide various advantages such as favourable release profiles and tailored drug delivery with outstanding physical-chemical stability. Solid lipid nanoparticles are spherical solid lipid particles that are distributed in water or an aqueous surfactant solution and are in the nanometer size range. Therefore, SLN is used to deliver hydrophilic and lipophilic drugs. The review article focuses on various aspects of SLN including the structure, the influence of excipients, the drug incorporation model, the principle of release, the method of preparation, characterization, the route of administration and biodistribution, and the application of SLN.\u0000","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47959682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Current NanosciencePub Date : 2023-05-25DOI: 10.2174/1573413719666230525093326
Majed M Masadeh, Ayham R. Alnsour, Rawand M. Daghmash, K. Alzoubi, Majd M Masadeh, Nayef H. Batayneh, Hala H. Batayneh, Mustafa S. Al-Ogaidi
{"title":"The Pharmaceutical Role of Silver Nanoparticles in Treating Multidrug-Resistant Bacteria and Biofilms","authors":"Majed M Masadeh, Ayham R. Alnsour, Rawand M. Daghmash, K. Alzoubi, Majd M Masadeh, Nayef H. Batayneh, Hala H. Batayneh, Mustafa S. Al-Ogaidi","doi":"10.2174/1573413719666230525093326","DOIUrl":"https://doi.org/10.2174/1573413719666230525093326","url":null,"abstract":"\u0000\u0000According to the WHO, antimicrobial resistance has recently become worrisome and constitutes an international public health crisis. The advent of multidrug-resistant bacteria has been implicated in the rise in morbidity and death caused by microbial diseases. However, the lack of new and effective antibiotics has been associated with the emergence of drug resistance. This has resulted in worldwide endeavors to advance innovative drugs with higher efficiency and more sophisticated drug delivery technologies. In addition, the utilization of nanoparticles as innovative biological substances is considered a worldwide issue of interest. \u0000Nanoparticles have the potential to become a vital and viable treatment alternative for treating drug-resistant illnesses. Nanoparticles contain metallic substances and their oxides, which have the highest possibility among all nanoparticles and have piqued the curiosity of numerous experts. Furthermore, using silver nanoparticles in photothermal treatment has attracted much interest.\u0000\u0000\u0000\u0000This review includes knowledge about the problems of drug resistance and the mechanism of action of silver nanoparticles.\u0000\u0000\u0000\u0000This review comprehensively assesses the current discoveries for using silver nanoparticles as antimicrobial medicines in infections caused by resistant microorganisms. Also being explored as nanomaterials that can react with light (photothermal treatment) to destroy bacteria and promote improved medication administration and release. Furthermore, it focuses on the synergy between nanoparticles with antimicrobial action and other nanoparticles, microbial adaptation mechanisms to nanoparticles, and existing obstacles and future possibilities that were thoroughly examined.\u0000","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48284376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}