Kelly C Cara, Joan Sabaté, Terryl J Hartman, Alpa V Patel, Caroline Y Um, Marissa M Shams-White
{"title":"Associations between White Meat-Only and Vegetarian Diets with Mortality from All Causes, Heart Diseases, Cancers, and Stroke in the American Cancer Society’s Cancer Prevention Study-II","authors":"Kelly C Cara, Joan Sabaté, Terryl J Hartman, Alpa V Patel, Caroline Y Um, Marissa M Shams-White","doi":"10.1016/j.cdnut.2026.109438","DOIUrl":"10.1016/j.cdnut.2026.109438","url":null,"abstract":"<div><h3>Background</h3><div>Many dietary guidelines recommend limiting or excluding red and processed meat to promote health and prevent chronic diseases.</div></div><div><h3>Objectives</h3><div>This study investigated associations between white meat-only and vegetarian diets and mortality from all causes, heart diseases, cancers, and stroke.</div></div><div><h3>Methods</h3><div>The American Cancer Society’s Cancer Prevention Study-II (CPS-II) cohort participants aged 30 to 95 y at baseline (1982) with mortality data through 2020 were examined (<em>n =</em> 998,378; 45% male, <em>n</em> = 626,017 deaths). A brief diet questionnaire identified meat intake [red/processed meat intake: high (≥6 d/wk); moderate (4 to <6 d/wk); low (0.5 to <4 d/wk); white meat-only; vegetarian]. Cox proportional hazards models adjusted for demographic, lifestyle, and health factors examined associations between diet categories and mortality risk. Effect modification by sex, smoking, BMI, baseline age group, and attained age was examined.</div></div><div><h3>Results</h3><div>Most participants consumed red/processed meat (high = 37%, moderate = 31%, low = 31%; white meat-only = 1%; vegetarian = 0.4%). Compared with high red/processed meat intake, low intake was associated with 1% to 5% lower mortality risk from all causes, heart diseases, and cancers across multiple strata, and 4% lower stroke mortality risk overall [hazard ratio (HR): 0.96; 95% confidence interval (CI): 0.94, 0.99]. White meat-only was associated with 5% to 7% lower all-cause mortality risk among males (HR: 0.93; 95% CI: 0.89, 0.98), individuals with healthy weight (HR: 0.95; 95% CI: 0.91, 0.98), and the 50 to 64 y age group (HR: 0.94; 95% CI: 0.90, 0.97), where results were similar with a vegetarian diet (50–64 y; HR: 0.94; 95% CI: 0.88, 1.00). Among participants reaching age ≥80, white meat-only was associated with lower all-cause (HR: 0.94; 95% CI: 0.91, 0.97) and cancer mortality risk (HR: 0.91; 95% CI: 0.83, 0.99). No other associations were statistically significant.</div></div><div><h3>Conclusions</h3><div>In CPS-II, limiting red/processed meat intake was associated with a small but significantly lower risk of all-cause and cause-specific mortality. Diets excluding red/processed meat may lower risk in certain subgroups, but large studies targeting these diets are needed to elucidate associations with mortality.</div></div>","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"10 8","pages":"Article 109438"},"PeriodicalIF":4.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148733638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nitya Rao, Arundhita Bhanjdeo, Madhuri Kamtam, Gurpreet Kaur, Tina Banerjee
{"title":"Building on Indigenous Knowledge for Strengthening Food Security and Nutrition: Evidence from a Community-based Intervention in Eastern India","authors":"Nitya Rao, Arundhita Bhanjdeo, Madhuri Kamtam, Gurpreet Kaur, Tina Banerjee","doi":"10.1016/j.cdnut.2026.109434","DOIUrl":"10.1016/j.cdnut.2026.109434","url":null,"abstract":"<div><h3>Background</h3><div>Indigenous communities in India face high rates of malnutrition despite living in biodiverse regions. Structural drivers, including declining forest cover due to land use changes (mining, urbanization, and infrastructure development), male outmigration, women’s time poverty, and the erosion of intergenerational food knowledge, exacerbate these inequities.</div></div><div><h3>Objectives</h3><div>The participatory action research project aimed to improve dietary diversity and nutrition among an Indigenous community—the Santals—in 2 development blocks in the states of Bihar and Jharkhand in Eastern India.</div></div><div><h3>Methods</h3><div>Building on a community-led, culturally grounded food and nutrition intervention, involving the documentation and nutritional analysis of local foods, and development and dissemination of 9 meal templates, data were collected through preinterventional and postinterventional assessment, designed as a knowledge, attitudes, and practices survey, with 684 individual women who were part of self-help groups (SHGs). Alongside this, focus group discussions with SHG members and semistructured interviews with 14 frontline workers and 2 local government (Panchayat) leaders were conducted. Participatory nutrition literacy workshops, recipe-based demonstrations, and training of local women as nutrition champions was undertaken.</div></div><div><h3>Results</h3><div>Postintervention, nutrition knowledge improved significantly (i.e., awareness of iron for anemia prevention rose from 45%–80%), alongside adoption of diverse, balanced diets. Approximately 65% of the women reported increased meal planning, inclusion of seasonal greens, eggs, local fish, and revived traditional recipes. The intervention strengthened women’s agency, food equity in households, peer-to-peer learning, and intergenerational knowledge exchange. Panchayat engagement and integration with government programs such as “Didi-Bari” (Sister’s garden) supported sustainability. The seasonality of food availability, water scarcity, and women’s time and labor for the collection and preparation of diverse diets remain key constraints.</div></div><div><h3>Conclusions</h3><div>Community-led, culturally relevant nutrition interventions can enhance dietary diversity, revive Indigenous knowledge, and empower women. Scaling these approaches through policy convergence offers a pathway toward equitable and sustainable food systems.</div></div>","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"10 8","pages":"Article 109434"},"PeriodicalIF":4.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148660154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Baiwen Peng, Kate Welshons, Trina Adler, Hyunjun Kim, Elder June M Blue
{"title":"Remembering What We Always Knew: Development of an Indigenous Diabetes Prevention Model","authors":"Baiwen Peng, Kate Welshons, Trina Adler, Hyunjun Kim, Elder June M Blue","doi":"10.1016/j.cdnut.2025.104570","DOIUrl":"10.1016/j.cdnut.2025.104570","url":null,"abstract":"<div><h3>Background</h3><div>Although the National Diabetes Prevention Program in the United States demonstrates success in physical health improvements, it lacks efficacy for recruiting and retaining Indigenous participants. In response to its shortcomings, diabetes prevention initiatives that integrate Indigenous traditional ecological knowledge emerged. Nevertheless, these initiatives also face various challenges that undermine their connections to authentic Indigenous needs, and their developments within the context of mainstream organizations are laden with complexity.</div></div><div><h3>Objectives</h3><div>The purpose of this initiative was to develop a culturally relevant diabetes prevention program for Indigenous women in the United States aged 40 and older that would address challenges to existing programs.</div></div><div><h3>Methods</h3><div>Informed by a detailed analysis of culturally relevant diabetes prevention programs in the United States and the Two-Eyed Seeing approach, the University of Minnesota Extension gathered an advisory council of Indigenous women-Elders to cocreate and field-test a culturally centered program model. Extension supported the process through sharing literature review findings, creating connections to national expertise in Indigenous diabetes prevention, and facilitating participatory evaluation.</div></div><div><h3>Results</h3><div>The initiative facilitated reconnection with Indigenous cultural practices and healthy living traditions through Indigenous activities. The program provided a sisterhood of support for the women as they explored and reclaimed their cultural identities. Outcomes reported by participants included increased sense of belonging, increased reliance on cultural ways for healthy living, increased capability to engage in cultural practices, increased confidence in using cultural medicines for health and healing for self and others, and improved confidence in Elder status.</div></div><div><h3>Conclusions</h3><div>Indigenous cultural approaches to health promotion emphasize community values, offer a holistic approach to health that integrates mental, physical, emotional, and spiritual well-being, and consciously recognize historical trauma and racism. Applying the Two-Eyed Seeing approach to program development can successfully integrate Indigenous cultural approaches to health promotion in the context of mainstream systems.</div></div>","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"10 ","pages":"Article 104570"},"PeriodicalIF":4.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149013937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Davrina Rianda, Lisa M Oakes, Charles D Arnold, Michaela C DeBolt, Matthews George, Aaron G Beckner, Kenneth M Maleta, Jennifer T Smilowitz, Christine P Stewart
{"title":"Growth Trajectories and Cognitive Outcomes in Childhood: A Comparative Study of Malawi and the USA","authors":"Davrina Rianda, Lisa M Oakes, Charles D Arnold, Michaela C DeBolt, Matthews George, Aaron G Beckner, Kenneth M Maleta, Jennifer T Smilowitz, Christine P Stewart","doi":"10.1016/j.cdnut.2026.107826","DOIUrl":"10.1016/j.cdnut.2026.107826","url":null,"abstract":"","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"10 ","pages":"Article 107826"},"PeriodicalIF":4.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148587472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Functional Performance in Response to a Dietary Guidelines for Americans Diet in Older Adults: Results From a Randomized-Controlled Crossover Diet Intervention","authors":"Cydne A Perry, Beate Henschel","doi":"10.1016/j.cdnut.2026.107755","DOIUrl":"10.1016/j.cdnut.2026.107755","url":null,"abstract":"","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"10 ","pages":"Article 107755"},"PeriodicalIF":4.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148587598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suyun Choi, Kristofer Terrell, Sung Gi Noh, Siyun Kim, Chaoyi Deng, Yi Wang, Oh Sung Kwon, Sangyong Choi
{"title":"Age-Dependent Effects of Zinc Deficiency on Skeletal Muscle Mitochondria and Metal Distribution","authors":"Suyun Choi, Kristofer Terrell, Sung Gi Noh, Siyun Kim, Chaoyi Deng, Yi Wang, Oh Sung Kwon, Sangyong Choi","doi":"10.1016/j.cdnut.2026.107738","DOIUrl":"10.1016/j.cdnut.2026.107738","url":null,"abstract":"","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"10 ","pages":"Article 107738"},"PeriodicalIF":4.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148587840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Activation of ARE/Nrf2 and Inhibition of NFƙB and AP-1 Are Involved in the Protective Effect of Phytonutrients in Human Skin Cells Under Mitochondrial Oxidative Stress","authors":"Yoav Sharoni, Aya Darawshe, Aviram Trachtenberg","doi":"10.1016/j.cdnut.2026.107787","DOIUrl":"10.1016/j.cdnut.2026.107787","url":null,"abstract":"","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"10 ","pages":"Article 107787"},"PeriodicalIF":4.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148587878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carolyn Sui, Fawaz G Haj, MingFo Hsu, Elizabeth Neumann
{"title":"Investigating the Impact of Liver-Specific Src Homology Phosphatase 2 Disruption in Lipid Metabolism in Alcohol-Associated Liver Disease and Acetaminophen Overdose","authors":"Carolyn Sui, Fawaz G Haj, MingFo Hsu, Elizabeth Neumann","doi":"10.1016/j.cdnut.2026.107759","DOIUrl":"10.1016/j.cdnut.2026.107759","url":null,"abstract":"","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"10 ","pages":"Article 107759"},"PeriodicalIF":4.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148588653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}