Current Developments in Nutrition最新文献

{"title":"The Adaptation, Implementation, and Performance Evaluation of Intake24, a Digital 24-h Dietary Recall Tool for South Asian Populations: The South Asia Biobank","authors":"Divya Bhagtani ,&nbsp;Birdem Amoutzopoulos ,&nbsp;Toni Steer ,&nbsp;David Collins ,&nbsp;Suzanna Abraham ,&nbsp;Bridget A Holmes ,&nbsp;Baldeesh K Rai ,&nbsp;Rajendra Pradeepa ,&nbsp;Sara Mahmood ,&nbsp;Abu Ahmed Shamim ,&nbsp;Poorvee Mathur ,&nbsp;Lathika Athauda ,&nbsp;Laksara De Silva ,&nbsp;Khadija I Khawaja ,&nbsp;Vinitaa Jha ,&nbsp;Anuradhani Kasturiratne ,&nbsp;Prasad Katulanda ,&nbsp;Malay K Mridha ,&nbsp;Ranjit M Anjana ,&nbsp;John C Chambers ,&nbsp;Nita G Forouhi","doi":"10.1016/j.cdnut.2025.104543","DOIUrl":"10.1016/j.cdnut.2025.104543","url":null,"abstract":"<div><h3>Background</h3><div>South Asia’s diverse food supply, food preparations, and eating behaviors require dietary instruments that reflect the consumption patterns of South Asians to enable context specific dietary assessment. Such instruments are not readily available for detailed dietary assessment at scale in South Asia.</div></div><div><h3>Objectives</h3><div>We describe the adaptation, implementation, and performance evaluation of Intake24, an open-source digital 24-h dietary recall tool, for dietary assessment in South Asia.</div></div><div><h3>Methods</h3><div>We adapted Intake24 for dietary assessment in the South Asia Biobank (SAB), a large population-based study in Bangladesh, India, Pakistan, and Sri Lanka. Intake24 adaptation encompassed the development of a South Asian food database with commonly consumed foods, linked with corresponding portion sizes, food probes, and nutrient information. Trained interviewers conducted the 24-h recalls. Performance of Intake24 was evaluated in 29,113 South Asian adults.</div></div><div><h3>Results</h3><div>The South Asia Intake24 food database included 2283 items and demonstrated good coverage of foods consumed across SAB regions. Median recall completion time was 13 min. Quality control metrics showed 99% of recalls included &gt;8 items and 8% had missing foods. Median energy intake was higher in younger individuals compared to older, and in males compared to females. Underweight participants reported lower energy intake, with no discernible difference across other BMI categories.</div></div><div><h3>Conclusions</h3><div>Intake24 enables comprehensive dietary assessment in regions of South Asia and will facilitate the analysis of dietary patterns, food and nutrient intake, and their relationship with health outcomes among South Asians.</div></div>","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"9 2","pages":"Article 104543"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Where” and “What” Do Adolescent Athletes Learn When It Comes to Food Literacy Compared With Adolescents that Do Not Play Sports? A Gender-Based Thematic Analysis","authors":"Alysha L Deslippe ,&nbsp;Coralie Bergeron ,&nbsp;Olivia Y Wu ,&nbsp;Kimberley J Hernandez ,&nbsp;Emilie Comtois-Rousseau ,&nbsp;Tamara R Cohen","doi":"10.1016/j.cdnut.2024.104525","DOIUrl":"10.1016/j.cdnut.2024.104525","url":null,"abstract":"<div><h3>Background</h3><div>Food literacy skills (e.g., nutrition knowledge, social, cultural, economic, and environmental impacts of food) play a role in high school (13–18 y) athletes’ health and performance. Literature suggests that adolescents are rarely taught concepts beyond nutrition knowledge, and experiences differ with gender or sports involvement. To improve all adolescents’ food literacy, we aimed to clarify differences in athletes’ and nonathletes’ food literacy to inform food literacy program design.</div></div><div><h3>Objectives</h3><div>The objective of this study was to contrast athletes’ and nonathletes’ food literacy using a gender lens.</div></div><div><h3>Methods</h3><div>We conducted 33 semistructured interviews with adolescents from a high school. Adolescents were recruited to balance sports involvement and sex with each self-identifying their gender (<em>n</em> = 15 boys; <em>n</em> = 14 girls; <em>n</em> = 4 nonbinary). Using inductive and deductive techniques, we thematically analyzed the data. Deductive codes were drawn from the Food Literacy for Young Adults Framework including Functional (e.g., nutrition literacy), Relational (e.g., joy in shared meals), and Systems (e.g., food sustainability) competencies.</div></div><div><h3>Results</h3><div>Functional competencies were learned most and often through social media. When it came to differences in food literacy experiences between athletes and nonathletes, athletes valued more credible sources of information (e.g., parents compared with peers) and viewed food as fuel (e.g., eating for hunger cues) instead of as a way to form social bonds. Gender also played a role in adolescents’ recognition of the connection between food and mental health (function competency) and the sources of information athlete boys and girls valued (personal knowledge compared with romantic partners).</div></div><div><h3>Conclusions</h3><div>Improving all adolescents’ food literacy starts with developing skills to judge information credibility (e.g., media literacy). Programs, where adolescent athletes and nonathletes learn together,should also address challenges these groups face, such as eating for performance compared with socialization, the impact of gender on how adolescents view associations between food and mental health, and credible sources of information.</div></div>","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"9 2","pages":"Article 104525"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143104013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplementation of Creatine Monohydrate Improves Sprint Performance but Has no Effect on Glycolytic Contribution: A Nonrandomized, Placebo-Controlled Crossover Trial in Trained Cyclists","authors":"Benedikt Meixner ,&nbsp;Johanna Stegmaier ,&nbsp;Peter Renner ,&nbsp;Karsten Koehler ,&nbsp;Woo-Hwi Yang ,&nbsp;Billy Sperlich","doi":"10.1016/j.cdnut.2025.104561","DOIUrl":"10.1016/j.cdnut.2025.104561","url":null,"abstract":"<div><h3>Background</h3><div>Sprint performance may be crucial for athletes in sprint and endurance sports. In this regard, the maximal glycolytic rate (νLa_max) is a variable within Mader’s model of metabolism that is commonly tested in a 15-s all-out sprint test. The product of lactate accumulation (ΔLa) and lactate distribution space approximated by fat-free mass (FFM) is strongly linked to sprint performance. Creatine monohydrate is a widely used ergogenic aid known for increasing anaerobic performance and FFM and the phosphagenic system contributes most to a 15-s all-out sprint.</div></div><div><h3>Objectives</h3><div>The aim of the study was to analyze the influence of creatine supplementation of 15-s work, FFM, and ΔLa.</div></div><div><h3>Methods</h3><div>Twenty male and 5 female cyclists underwent a placebo-controlled, crossover design with 4 laboratory visits. After a familiarization trial, baseline measurements were performed. Placebo (4 × 5 g/d maltodextrin) and creatine monohydrate (4 × 5 g/d) were administered for 5 d before the respective trials. All participants underwent this order of trials and performed a 15-s all-out sprint test on a Cyclus2-ergometer. Capillary blood was sampled before and every minute (for 8 min) after the sprint to determine ΔLa. Body composition was determined employing bioelectric impedance analysis.</div></div><div><h3>Results</h3><div>Creatine supplementation significantly increased 15-s work output and FFM compared with baseline and placebo conditions. However, no significant differences were found in capillary blood lactate accumulation (ΔLa) or glycolytic contribution.</div></div><div><h3>Conclusions</h3><div>The results indicate potential differences in limitations of sprint performance of participants. Responders to creatine supplementation are potentially limited by mechanical or metabolic factors. The findings of this study highlight the importance of considering supplementation of creatine monohydrate when undergoing testing for the maximal glycolytic rate.</div></div>","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"9 2","pages":"Article 104561"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143429490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital Marketing of Unhealthy Foods and Non-alcoholic Beverages to Children and Adolescents: A Narrative Review","authors":"Gabriela Fretes ,&nbsp;Paula Veliz ,&nbsp;Ana Maria Narvaez ,&nbsp;D’Arcy Williams ,&nbsp;Romain Sibille ,&nbsp;Maaike Arts ,&nbsp;Jef L Leroy","doi":"10.1016/j.cdnut.2025.104545","DOIUrl":"10.1016/j.cdnut.2025.104545","url":null,"abstract":"<div><div>With growing access to electronic devices and time spent online, the food and beverage industry increasingly uses digital media to market unhealthy foods and non-alcoholic beverages (high in unhealthy fats, sugars, and/or salt and often highly processed) to children and adolescents. We conducted a narrative review of the global evidence on digital marketing of these foods and drinks and studied policies and regulations in Latin American and Caribbean (LAC) countries. Evidence was limited to a few high, upper-middle and lower-middle income countries where children and adolescents were found to be extensively exposed to the digital marketing of unhealthy foods and non-alcoholic beverages and this exposure increased with age. A wide range of purposefully designed marketing techniques were used. Exposure to the digital marketing of unhealthy foods appears to be followed by increased consumption, but the quality of the evidence was limited. Accurate assessment of exposure was a shortcoming in most studies. Stronger evidence will require studies with more rigorous designs that minimize confounding and objectively quantify individual exposure. Mandatory comprehensive policies are needed that limit exposure of children and adolescents to the marketing of unhealthy foods and non-alcoholic beverages irrespective of the medium or platform they use. The experience of LAC countries may provide insights for the development of effective policies in other countries. Novel technologies that can be used by governments to monitor digital marketing regulations are needed.</div></div>","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"9 2","pages":"Article 104545"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143438147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Berberine Inhibits Breast Cancer Stem Cell Development and Decreases Inflammation: Involvement of miRNAs and IL-6","authors":"Nour Ibrahim ,&nbsp;Nawal Alsadi ,&nbsp;Hamed Yasavoli-Sharahi ,&nbsp;Roghayeh Shahbazi ,&nbsp;Mary Joe Hebbo ,&nbsp;Darshan Kambli ,&nbsp;Florencia Balcells ,&nbsp;Chantal Matar","doi":"10.1016/j.cdnut.2024.104532","DOIUrl":"10.1016/j.cdnut.2024.104532","url":null,"abstract":"<div><h3>Background</h3><div>Breast cancer (BC) is a health concern worldwide and is often accompanied by depressive symptoms in patients. In BC, elevated interleukin-6 (IL-6) levels contribute to an inflammatory signature linked to cancer stem cell (CSC) stemness and depressive behaviors. Bioactive food components, such as berberine (BBR), have preventative effects against BC by targeting CSCs.</div></div><div><h3>Objectives</h3><div>This study aimed to investigate the effects of BBR on breast CSC proliferation, on levels of specific micro (mi)RNAs and IL-6 in vitro and in vivo, and in alleviating depressive-like behaviors in mice with BC.</div></div><div><h3>Methods</h3><div>Mammosphere formation assays were conducted by treating murine 4T1 and human MDA-MB-231 BC cell lines with BBR. qPCR analysis of miRNAs miR-let-7c and miR-34a-5p was performed on 4T1 CSCs exposed to BBR. BBR was administered orally to female BALB/c, followed by injection with mammary carcinoma cells to induce BC. Behavioral tests were conducted to assess depressive-like behaviors. Tumor tissues were collected for ex vivo mammosphere assays, miRNA expression analysis, and IL-6 detection by ELISA. Serum was also collected for IL-6 analysis.</div></div><div><h3>Results</h3><div>BBR treatment inhibited mammosphere formation and proliferation of CSCs derived from 4T1 and MDA-MB-231 cell lines. Quantification of mammosphere formation showed a significant decrease in both cell lines at 75 μM BBR (4T1: <em>P</em> &lt; 0.001; MDA-MB-231: <em>P</em> &lt; 0.0001). BBR upregulated the expression of miRNAs miR-let-7c and miR-34a in both cell lines, with miR-34a showing a significant increase (<em>P</em> &lt; 0.001) and let-7c showing a significant increase (<em>P</em> &lt; 0.05) in expression. In vivo, oral administration of BBR reduced mammosphere formation in breast tumor tissues (<em>P</em> &lt; 0.0001) and elevated expression of miR-145 and miR-34a, with both showing significant upregulation (<em>P</em> &lt; 0.0001), indicating its potential tumor-suppressive effects. BBR treatment resulted in a significant decrease in serum IL-6 levels (<em>P</em> &lt; 0.05), suggesting anti-inflammatory properties, while the IL-6 in tumor tissue did not show significant changes (<em>P</em> &gt; 0.05). However, no significant differences were observed in depressive-like behaviors between control and treatment groups.</div></div><div><h3>Conclusions</h3><div>BBR may have the potential to be used as an “Epi-Natural Compound” to prevent cancer by reducing inflammation and affecting epigenetics.</div></div>","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"9 2","pages":"Article 104532"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"School Milk Programs in Latin America and the Caribbean","authors":"Ayala Wineman ,&nbsp;Maria Martinez ,&nbsp;Nicole Jacquet ,&nbsp;Eth Ludmilla Rodrigues ,&nbsp;Arlene Mitchell","doi":"10.1016/j.cdnut.2024.104541","DOIUrl":"10.1016/j.cdnut.2024.104541","url":null,"abstract":"<div><h3>Background</h3><div>School milk programs have a long history in Latin America and the Caribbean. In recent decades, the region has undergone a nutrition transition characterized by a rise in children’s overweight/obesity, which adds new challenges for school-based programs.</div></div><div><h3>Objectives</h3><div>This article aimed to unpack how school milk programs in the region have fared as of 2022 and what drives their success (or lack thereof).</div></div><div><h3>Methods</h3><div>Data from the Global Survey of School Meal Programs were analyzed descriptively to broadly summarize the current state of school feeding programs in Latin America and the Caribbean. To probe the status of school milk programs, key informant interviews were conducted with school milk stakeholders in 7 countries (Brazil, Chile, Colombia, the Dominican Republic, Ecuador, Guatemala, and Honduras), and these interviews were analyzed for thematic elements.</div></div><div><h3>Results</h3><div>Five countries were found to have operational school milk programs, whereas the programs in Guatemala and Honduras have not (thus far) endured. Programs often prioritized and took pride in local milk procurement, although there was sometimes incongruity between objectives to improve children’s diets and stimulate local agricultural development. Program implementers grapple with the taste, texture, and safety of milk, and it can be challenging to reconcile concerns over child obesity and the need to ensure the milk is appealing and accepted.</div></div><div><h3>Conclusions</h3><div>In conclusion, programs seek creatively to overcome the aformentioned challenges wherever there is fiscal capacity and political will.</div></div>","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"9 2","pages":"Article 104541"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Dietary Intake and Cardiorespiratory Fitness on Glycemic Variability in Adolescents: An Observational Study","authors":"Mingliang Ge ,&nbsp;Stephanie R Lebby ,&nbsp;Shivani Chowkwale ,&nbsp;Caleb Harrison ,&nbsp;Grace M Palmer ,&nbsp;Keith J Loud ,&nbsp;Diane Gilbert-Diamond ,&nbsp;Mary Ellen Vajravelu ,&nbsp;Jennifer L Meijer","doi":"10.1016/j.cdnut.2025.104547","DOIUrl":"10.1016/j.cdnut.2025.104547","url":null,"abstract":"<div><h3>Background</h3><div>Cardiorespiratory fitness (CRF), estimated by maximum oxygen consumption (VO₂ max) during exercise, is worsening among adolescents and associated with a decline in metabolic health into adulthood. Glycemic patterns may provide a mechanism between CRF and health.</div></div><div><h3>Objectives</h3><div>This study assessed the feasibility of measuring glycemic patterns using continuous glucose monitoring (CGM) in adolescents, aged 14–22 y, to estimate the relationship between VO₂ max and glucose patterns.</div></div><div><h3>Methods</h3><div>Healthy adolescents (<em>n</em> = 30) were recruited for a treadmill VO₂ max test and to complete the following activities for 7–10 d: <em>1</em>) wear a Dexcom G6 CGM, <em>2</em>) complete ≥3 24-h dietary recalls, and <em>3</em>) complete 1 at-home oral glucose tolerance test (OGTT, 75 g glucose). Glycemic patterns were extracted as mean glucose, the coefficient of variance, the mean amplitude of glycemic excursions, and the mean of daily differences. The 2-h glucose responses to the OGTT and individual meals were extracted. Statistical analyses evaluated the relationship between VO₂ max and <em>1</em>) overall glycemic patterns and <em>2</em>) the maximum glucose level and AUC response to OGTT and meals, stratified by sex.</div></div><div><h3>Results</h3><div>Participant feasibility demonstrated that 90% completed CGM data (<em>n</em> = 27), 87% ≥7 d of CGM data (<em>n</em> = 26), 97% attempted OGTT (<em>n</em> = 29), and 93% completed ≥3 dietary recalls (<em>n</em> = 28). Most participants had normal BMI (70%) with an even distribution of sex (44% male). Males exhibited an inverse relationship between VO₂ max and overall mean glucose (ß= –7.7, <em>P</em> = 0.04). Males demonstrated an inverse relationship between VO₂ max and <em>1</em>) maximum glucose (ß = –29, <em>P</em> = 0.006) and AUC (ß = –2702, <em>P</em> = 0.001) in response to the OGTT and <em>2</em>) AUC (ß = –1293, <em>P</em> = 0.03) in response to meals. No association was observed between VO₂ max and glucose patterns in females.</div></div><div><h3>Conclusions</h3><div>A sex-specific relationship between VO₂ max and glycemic patterns was observed, suggesting a unique metabolic capacity during late adolescence by sex.</div><div>This trial was registered at <span><span>clinicaltrials.gov</span><svg><path></path></svg></span> as NCT05845827.</div></div>","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"9 2","pages":"Article 104547"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143317187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Life Expectancy Gain of Implementing the Nordic Nutrition Recommendations 2023: Modeling From 8 Nordic and Baltic Countries","authors":"Elaheh Javadi Arjmand ,&nbsp;Erik K Arnesen ,&nbsp;Øystein Ariansen Haaland ,&nbsp;Jan-Magnus Økland ,&nbsp;Katherine M Livingstone ,&nbsp;John C Mathers ,&nbsp;Carlos Celis-Morales ,&nbsp;Kjell Arne Johansson ,&nbsp;Lars T Fadnes","doi":"10.1016/j.cdnut.2024.104540","DOIUrl":"10.1016/j.cdnut.2024.104540","url":null,"abstract":"<div><h3>Background</h3><div>Dietary guidelines play a key role in promoting health and preventing chronic diseases. The Nordic Nutrition Recommendations (NNR) 2023 provide updated recommendations for healthy eating relevant for the Nordic and Baltic countries, but the potential benefits have yet to be quantified.</div></div><div><h3>Objectives</h3><div>This study aimed to project the population health benefits, specifically, potential gains in life expectancy in Nordic and Baltic countries resulting from long-term dietary changes from current dietary patterns within each country to NNR2023.</div></div><div><h3>Methods</h3><div>For this population-based mathematical model, using the Food4HealthyLife 2.0 calculator, data were obtained from meta-analyses on associations between each food group and mortality, and background mortality data were derived from the Global Burden of Disease study. Standard life-table methods were used, accounting for the correlation between 14 food groups and the anticipated time delay between dietary changes and health effects.</div></div><div><h3>Results</h3><div>For 40-y-old females and males, projected life expectancy gains were from 1.8 and 2.1 y in Finland to 3.4 and 4.1 y, respectively, in Lithuania, changing to feasible NNR2023. Correspondingly, when changing to full-potential NNR2023, gains ranged from 4.4 and 5.0 y in Finland to 6.1 and 7.3 y, respectively, in Lithuania. The largest gains in life expectancy were linked to consuming more legumes (18%), nuts (17%), whole grains (12%), and less processed meat (14%) and added sugars (13%).</div></div><div><h3>Conclusions</h3><div>Adopting dietary patterns in line with the NNR2023 is associated with considerable gains in life expectancy in the Nordic and Baltic countries. The study contributes to the evidence base to support policy measures to achieve NNR2023.</div></div>","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"9 2","pages":"Article 104540"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Pomegranate Supplementation on Markers of Exercise-Induced Muscle Damage: A Systematic Review and Meta-Analysis","authors":"Saba Belyani ,&nbsp;Fatemeh Kazeminasab ,&nbsp;Mahnaz Niazi ,&nbsp;Reza Bagheri ,&nbsp;Mahsa Mahabadi Hesari ,&nbsp;Sara K Rosenkranz ,&nbsp;Donny M Camera ,&nbsp;Fred Dutheil","doi":"10.1016/j.cdnut.2025.104560","DOIUrl":"10.1016/j.cdnut.2025.104560","url":null,"abstract":"<div><h3>Background</h3><div>Pomegranate supplementation has been shown to reduce oxidative stress and inflammation, with some evidence suggesting it may accelerate recovery from exercise-induced muscle damage (EIMD), including metabolic, mechanical, and neuromuscular recovery.</div></div><div><h3>Objectives</h3><div>This systematic review and meta-analysis aimed to investigate the effects of pomegranate supplementation on markers of EIMD.</div></div><div><h3>Methods</h3><div>A systematic search of Scopus, PubMed, and Web of Science up to January 2024 identified studies evaluating pomegranate supplementation and exercise recovery. Studies involving athletes and nonathletes aged 18–55 were included. Weighted mean differences (WMDs) were calculated for EIMD markers. Study quality was assessed using a modified physiotherapy evidence database scale. This review was registered with the International Prospective Register of Systematic Reviews (ID: CRD42024536905).</div></div><div><h3>Results</h3><div>Ten studies were included in the meta-analysis. Pomegranate supplementation did not significantly affect markers of metabolic recovery, including myoglobin (WMD: –1.344 ng/mL; 95% confidence interval (CI): –4.11, 1.42 ng/mL, <em>P</em> = 0.342) and creatine kinase (WMD: –11.990 U/L; 95% CI: –28.64, 4.66 U/L, <em>P</em> = 0.158), or neuromuscular recovery, as indicated by lactate concentrations (WMD: –0.093 mmol/L; 95% CI: –0.39, 0.21 mmol/L, <em>P</em> = 0.546). Muscle soreness also remained unchanged (WMD: 0.999; 95% CI: –0.18, 2.17, <em>P</em> = 0.097). However, a significant reduction in lactate dehydrogenase amounts (WMD: –21.152 U/L; 95% CI: –39.29, –3.01 U/L, <em>P</em> = 0.022) immediately postexercise suggests a short-term protective effect against mechanical muscle damage.</div></div><div><h3>Conclusions</h3><div>Pomegranate supplementation does not appear to enhance overall recovery markers for EIMD but may offer short-term benefits for mechanical muscle damage. Standardizing supplementation regimens, dosages, and exercise protocols is crucial to better understand the potential benefits of pomegranate supplementation in EIMD recovery.</div></div>","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"9 2","pages":"Article 104560"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143403178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Informing the Design of Large-Scale Food Fortification Programs with Secondary Data: Pilot Results from Nigeria and Zambia","authors":"Katherine P Adams ,&nbsp;Emmanuel A Gyimah ,&nbsp;Svenja M Jungjohann ,&nbsp;Jacqueline L Hems ,&nbsp;Musonda J Mofu ,&nbsp;Olufolakemi Mercy Anjorin ,&nbsp;Jennifer Yourkavitch ,&nbsp;Silvia Alayón ,&nbsp;Heather Danton ,&nbsp;Ingrid Weiss ,&nbsp;Omar Dary ,&nbsp;Monica B Woldt","doi":"10.1016/j.cdnut.2024.104522","DOIUrl":"10.1016/j.cdnut.2024.104522","url":null,"abstract":"<div><h3>Background</h3><div>Large-scale food fortification (LSFF) can improve micronutrient intake, but low-income and middle-income countries often lack resources to collect data for LSFF decision making. We designed a methodology using existing data and methods to inform LSFF programming.</div></div><div><h3>Objectives</h3><div>This study aimed to pilot a methodology using existing diet, market, and diet cost data and assess its implementation feasibility and usefulness for LSFF decision making.</div></div><div><h3>Methods</h3><div>We used household food consumption/availability data from Nigeria and Zambia to assess dietary micronutrient inadequacy and model contributions of LSFF. Market survey (Nigeria) and agrifood information system (Zambia) data were used to estimate availability of fortifiable foods. We used Cost of the Diet software to estimate affordability of an adequate diet in Zambia. We engaged country stakeholders to determine modeling parameters and assess methodology implementation.</div></div><div><h3>Results</h3><div>The analyses took ∼6 mo and cost ∼150,000 USD (Nigeria) and ∼250,000 USD (Zambia). Results showed diets were inadequate to meet vitamin A, folate, and zinc requirements of 32%–67% of households in Nigeria and 51%–83% of households in Zambia. Modeling existing LSFF in Nigeria demonstrated improved micronutrient adequacy of diets, with further improvements possible with rice fortification. In Zambia, existing vitamin A–fortified sugar marginally reduced inadequacy. Introducing mandatory wheat flour and/or maize flour fortification could reduce folate and zinc inadequacies. The market assessment demonstrated widespread availability of fortifiable edible oil, sugar, and wheat flour, but not fortifiable maize flour. The cost of the diet in Zambia with LSFF was similar to the cost without LSFF. Stakeholders found the methodology’s components together generated useful, timely evidence for LSFF programming.</div></div><div><h3>Conclusions</h3><div>Our methodology showed opportunities for improving the micronutrient adequacy of diets in Nigeria and Zambia through LSFF. The methodology generated evidence that stakeholders agreed can support LSFF planning. Investments and strategies are needed to strengthen capacity to conduct the assessments, reduce costs, and streamline methods.</div></div>","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"9 2","pages":"Article 104522"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}