Critical reviews in analytical chemistry最新文献_第4页

CRISPR/Cas System-Based Fluorescent Sensor for Analysis and Detection. 基于CRISPR/Cas系统的荧光分析检测传感器。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-03-24 DOI: 10.1080/10408347.2025.2481409

Huiru Niu, Lina Zou, Yanan Liu, Zheng Li, Huanyu Ren, Hao Liao, Xiaojing Zhang, Shanshan An, Fei Ren, Xiuhong Ge, Lang Cheng, Feiyan Yang, Hongzhi Pan, Shengzhong Rong, Dong Chang, Hongkun Ma

引用次数: 0

Recent Advances in Electrochemical Aptasensors for Detection of Clinical and Veterinary Drugs. 用于临床和兽药检测的电化学感应传感器研究进展。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-03-18 DOI: 10.1080/10408347.2025.2469781

Masoomeh Naseri, Ali Niazi, Atisa Yazdanipour, Kowsar Bagherzadeh

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Anti-diabetic Biologicals: Exploring the Role of Different Analytical Techniques. 抗糖尿病生物制剂：探讨不同分析技术的作用。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-03-15 DOI: 10.1080/10408347.2025.2472793

Zahid Yaseen, Mukesh Nandave, Lalit Sharma

{"title":"Anti-diabetic Biologicals: Exploring the Role of Different Analytical Techniques.","authors":"Zahid Yaseen, Mukesh Nandave, Lalit Sharma","doi":"10.1080/10408347.2025.2472793","DOIUrl":"https://doi.org/10.1080/10408347.2025.2472793","url":null,"abstract":"Antidiabetic biologicals (ADBs) have revolutionized the treatment of diabetes mellitus, once considered incurable through conventional medicine. These biological products, derived from natural sources via extraction, semi-synthesis, or recombinant DNA technology, include insulin and its analogs, GLP-1 receptor agonists, amylin analogs, and the recently approved monoclonal antibody teplizumab. Regulatory authorities worldwide have established QC parameters outlined in pharmacopoeias, alongside analytical techniques to ensure their safety and efficacy. This review focuses on the analytical techniques used to assess QC parameters of ADBs, including chromatographic methods, spectroscopic techniques, capillary electrophoresis, immunoassays, and endotoxin testing. Key parameters such as identification, potency, purity, and impurity profiling are thoroughly examined. The paper provides a comprehensive and up-to-date compilation of QC requirements and methodologies, along with a detailed comparison of analytical techniques. In doing so, it highlights their advantages and limitations, offering valuable insights for researchers and regulatory professionals involved in selecting suitable methods for QC assessment and understanding the complexities of ADBs evaluation. Furthermore, the article discusses the paramount importance of QC and future perspectives, emphasizing the transition to advanced versions of current techniques driven by the need for efficiency and reliability in quality testing.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-22"},"PeriodicalIF":4.2,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolomics as a Tool for Unraveling the Impact of Enantioselectivity in Cellular Metabolism. 代谢组学作为揭示细胞代谢中对映体选择性影响的工具。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-03-04 DOI: 10.1080/10408347.2025.2468926

Ana Sofia Almeida, Paula Guedes de Pinho, Fernando Remião, Carla Fernandes

{"title":"Metabolomics as a Tool for Unraveling the Impact of Enantioselectivity in Cellular Metabolism.","authors":"Ana Sofia Almeida, Paula Guedes de Pinho, Fernando Remião, Carla Fernandes","doi":"10.1080/10408347.2025.2468926","DOIUrl":"https://doi.org/10.1080/10408347.2025.2468926","url":null,"abstract":"Metabolomics is an emerging interdisciplinary field focused on the comprehensive analysis of all metabolites within biological samples, making it valuable for areas such as drug development, and environmental analysis. Many compounds, including pharmaceuticals and agrochemicals that have been extensively studied by metabolomics are chiral. The intrinsic chirality of biological targets can lead to a selective recognition of enantiomers resulting in distinct pharmacokinetic, pharmacodynamic and/or toxicological profiles (enantioselectivity). Given that metabolomics captures an instant snapshot of an organism's metabolic state, it serves as a powerful tool to investigate chiral compounds and understand enantioselective effects. Herein, a systematic compilation of scientific literature was performed and 48 enantioselectivity studies using metabolomics were selected. These studies revealed an increasing focus on chiral pesticides (77%), the use of animal models (59%), reliance on LC-MS techniques (52%), and predominantly untargeted approaches (83%). Enantioselective effects were described in most studies. This review describes significant advances in this emerging field and highlights the use of metabolomics to unravel the role of stereochemistry in cellular metabolism by the examination of enantiomer-specific metabolic effects. Furthermore, it elucidates enantioselectivity mechanism that can be further applied to other groups of chiral compounds.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-21"},"PeriodicalIF":4.2,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Statement of Retraction: Recent Progress in Aptamer-Functionalized Metal-Organic Frameworks-Based Optical and Electrochemical Sensors for Detection of Mycotoxins. 撤回声明：用于真菌毒素检测的适配体功能化金属有机框架光学和电化学传感器的最新进展。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-02-21 DOI: 10.1080/10408347.2024.2437855

引用次数: 0

Statement of Retraction: Current Progress in Aptasensor for Ultra-Low Level Monitoring of Parkinson's Disease Biomarkers. 撤回声明：超低水平监测帕金森病生物标志物的aptassensor的最新进展。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-02-21 DOI: 10.1080/10408347.2024.2437859

引用次数: 0

Statement of Retraction: Optical and Electrochemical Aptasensors Developed for the Detection of Alpha-Fetoprotein. 撤回声明：开发用于检测甲胎蛋白的光学和电化学感应传感器。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-02-21 DOI: 10.1080/10408347.2024.2437857

引用次数: 0

Recent Developments in Colorimetric and Fluorimetric Chemosensors for the Detection of Mn²⁺ Ions: A Review (2010-2024). 比色和荧光化学传感器检测Mn2+离子的最新进展：综述（2010-2024）。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-02-19 DOI: 10.1080/10408347.2025.2460091

Eid H Alosaimi

{"title":"Recent Developments in Colorimetric and Fluorimetric Chemosensors for the Detection of Mn2+ Ions: A Review (2010-2024).","authors":"Eid H Alosaimi","doi":"10.1080/10408347.2025.2460091","DOIUrl":"https://doi.org/10.1080/10408347.2025.2460091","url":null,"abstract":"Manganese is an essential metal ion involved in various biological and environmental processes, but its excess can lead to toxicity, particularly affecting the nervous system. Therefore, developing selective and sensitive detection methods for Mn2+ ions is of paramount importance. Colorimetric and fluorimetric chemosensors have emerged as promising tools for the detection of Mn2+ due to their simplicity, cost-effectiveness, and real-time monitoring capabilities. This review discusses recent advances in the colorimetric and fluorimetric chemosensors that exhibit distinct color or fluorescence changes upon interaction with Mn2+ ions. The review explores different organic and nanomaterials, focusing on their mechanisms of sensing, sensitivity, selectivity, and practical applications in environmental monitoring, healthcare, and food safety. The article also provides insights into future research directions aimed at overcoming these challenges, improving chemosensor performance, and expanding the applicability of colorimetric and fluorimetric chemosensors for Mn2+ detection in diverse real-world scenarios.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-21"},"PeriodicalIF":4.2,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analytical Capabilities and Future Perspectives of Chemometrics in Omics for Food Microbial Investigation. 化学计量学在食品微生物组学研究中的分析能力及未来展望。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-02-13 DOI: 10.1080/10408347.2025.2463430

Feifei Sun, Yu Zhang, Chin Ping Tan, Ying Gu, Yuanfa Liu, Yong-Jiang Xu

{"title":"Analytical Capabilities and Future Perspectives of Chemometrics in Omics for Food Microbial Investigation.","authors":"Feifei Sun, Yu Zhang, Chin Ping Tan, Ying Gu, Yuanfa Liu, Yong-Jiang Xu","doi":"10.1080/10408347.2025.2463430","DOIUrl":"https://doi.org/10.1080/10408347.2025.2463430","url":null,"abstract":"Microbiomes significantly impact food flavor, food quality and human health. The development of omics technologies has revolutionized our understanding of the microbiome, the generated complex datasets, as well as their processing and interpretation need to be taken seriously. Currently, chemometrics has shown huge potential in omics data analysis, which is crucial to reveal the functional attributes and mechanisms of microbiomes in food nutrition and safety. However, various chemometric tools have their own characteristics, selecting appropriate technologies and performing multiomics data fusion analysis to improve the precision and reliability of food microbial investigations is still a huge challenge. In this review, we summarized the omics technologies used in food microbiome studies, overviewed the principle and applicability of chemometrics in omics, and discussed the challenges and prospects of chemometrics. The urgent need for chemometrics is to integrate deep learning (DL) and artificial intelligence algorithms to enhance its analytical capabilities and prediction accuracy. We hope this review will provide valuable insights of the integration of multiomics and bioinformatics combined with various chemometric techniques in data analysis for food microbial investigation. In the future, chemometrics combined with modern technologies for multiomics data analysis will further deepen our understanding of food microbiology and improve food safety.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-14"},"PeriodicalIF":4.2,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Application of Inductively Coupled Plasma Mass Spectrometry in Cancer Research. 电感耦合等离子体质谱法在癌症研究中的应用。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-02-13 DOI: 10.1080/10408347.2025.2463437

Zhikun Zang, Xiaolan Liu, Meng Wang, Zhibin Wang

{"title":"The Application of Inductively Coupled Plasma Mass Spectrometry in Cancer Research.","authors":"Zhikun Zang, Xiaolan Liu, Meng Wang, Zhibin Wang","doi":"10.1080/10408347.2025.2463437","DOIUrl":"https://doi.org/10.1080/10408347.2025.2463437","url":null,"abstract":"Inductively coupled plasma mass spectrometry (ICP-MS) technology has demonstrated immense potential in cancer research. This paper explores the diverse applications and significance of ICP-MS in this field. ICP-MS plays a pivotal role in tumor marker detection by enabling the identification of cancer-related biomolecules through elemental labeling, such as metallic labeling of antibodies or nucleic acids, and by detecting cancer cell surface markers. Additionally, it facilitates the discovery of potential biomarkers by analyzing elemental changes and their metabolites in biological fluids and tissue samples. Single-cell ICP-MS techniques provide insights into cell-to-cell heterogeneity, offering cell-level information for cancer studies. In the realm of metallic anticancer drug research, ICP-MS is employed to investigate drug uptake and distribution. This includes analyzing metallodrug uptake in cells, and distribution in tissues and organs at the single-cell level, and elucidating anticancer mechanisms by monitoring the distribution and metabolism of these metallodrugs. The application of ICP-MS in cancer research offers robust technical support for early diagnosis, treatment evaluation, and drug discovery, promising broad prospects in this domain.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-25"},"PeriodicalIF":4.2,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0