Critical reviews in analytical chemistry最新文献_第4页

GC-IMS in Medicine: Transforming Diagnostics with Sensitivity and Speed. 医学中的气相色谱- ims：以灵敏度和速度转变诊断。

IF 5.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-07-28 DOI: 10.1080/10408347.2025.2536822

Xiaoyue Zhao, Miao Zhang, Jing He, Xin Li, Xuewei Zhuang

{"title":"GC-IMS in Medicine: Transforming Diagnostics with Sensitivity and Speed.","authors":"Xiaoyue Zhao, Miao Zhang, Jing He, Xin Li, Xuewei Zhuang","doi":"10.1080/10408347.2025.2536822","DOIUrl":"https://doi.org/10.1080/10408347.2025.2536822","url":null,"abstract":"Rapid, nondestructive, high-throughput volatile constituent screening and detection is becoming more and more crucial in the medical field's illness analysis. GC-IMS, or gas chromatography-ion mobility spectrometry, is a potent method for the sensitive identification and separation of volatile organic molecules. GC-IMS enables rapid detection with high sensitivity, allowing for the identification of volatile organic compounds (VOCs) in a short time, making it particularly suitable for rapid screening and on-site analysis. This technique is user-friendly, requiring no complex sample preparation and enabling direct analysis, thereby streamlining the workflow and reducing time costs. Moreover, the equipment is portable and has low maintenance costs, offering significant potential for widespread application. The operating idea of GC-IMS is briefly explained in this study, along with recent research that has used GC-IMS on various human metabolites, such as urine, feces, bile, serum, and exhaled breath, for purposes like disease and pathogenic microbe differential detection. Lastly, a summary and recommendation are made on the future development direction of GC-IMS.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-17"},"PeriodicalIF":5.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144728501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent Developments in Colorimetric and Fluorimetric Sensing of Fe²⁺ and Fe³⁺ Ions: A Review (2021 to 2025). Fe2+和Fe3+离子的比色和荧光传感的最新进展：综述（2021年至2025年）。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-07-23 DOI: 10.1080/10408347.2025.2531970

Ali Q Alorabi

{"title":"Recent Developments in Colorimetric and Fluorimetric Sensing of Fe2+ and Fe3+ Ions: A Review (2021 to 2025).","authors":"Ali Q Alorabi","doi":"10.1080/10408347.2025.2531970","DOIUrl":"https://doi.org/10.1080/10408347.2025.2531970","url":null,"abstract":"Iron ions, Fe2+ and Fe3+, play essential roles in biological, environmental, and industrial processes. However, their imbalance can lead to severe health and ecological issues, including oxidative stress-related diseases and water contamination. Both metal ions are commonly found in environmental water sources, biological fluids, and food products, necessitating their precise detection and quantification. Colorimetric and fluorimetric chemosensors are powerful tools, offering simple, rapid, and highly sensitive methods for monitoring Fe2+ and Fe3+ ions. These chemosensors are based on changes in color or fluorescence intensity upon interaction with target ions, providing clear and easily interpretable signals. Both types of chemosensors can be designed using organic molecules, polymers, or nanomaterials, each with unique advantages in selectivity, stability, and sensitivity, making them highly effective for environmental and biological ion detection. The aim of this review is to provide a comprehensive overview of the recent advancements in the development of colorimetric and fluorimetric chemosensors for the detection of Fe2+ and Fe3+ ions, with a focus on innovations from 2021 to 2025. This review explores the progress in organic, polymeric, and nanomaterial-based chemosensors, highlighting their design, sensing mechanisms, and practical applications. By examining the sensitivity, selectivity, and stability of these chemosensors, the review aims to identify key trends, challenges, and future directions in the field, offering valuable insights for researchers and practitioners working on the detection of Fe2+ and Fe3+ in environmental, biological, and industrial contexts.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-18"},"PeriodicalIF":4.2,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144697833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent Advances in Organic Colorimetric and Fluorimetric Detection of Co²⁺ Ions: Strategies, Challenges, and Future Perspectives (2020-2025). 有机比色法和荧光法检测Co2+离子的最新进展：策略、挑战和未来展望（2020-2025）。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-07-16 DOI: 10.1080/10408347.2025.2527741

Mohsen A M Alhamami

{"title":"Recent Advances in Organic Colorimetric and Fluorimetric Detection of Co2+ Ions: Strategies, Challenges, and Future Perspectives (2020-2025).","authors":"Mohsen A M Alhamami","doi":"10.1080/10408347.2025.2527741","DOIUrl":"https://doi.org/10.1080/10408347.2025.2527741","url":null,"abstract":"Cobalt is essential in various biological systems, but their excessive accumulation can pose significant health and ecological risks. The development of sensitive, selective, and rapid detection methods is crucial for monitoring Co2+ contamination in water, food, and biological samples. Organic fluorimetric and colorimetric chemosensors have gained considerable attention due to their high sensitivity, simplicity, and real-time detection capabilities. These chemosensors function through fluorescence quenching/enhancement and visible color changes induced by Co2+ interactions, enabling efficient and portable detection. Recent advancements have focused on designing novel organic fluorophores that improve selectivity, response time, and detection limits. This review provides a comprehensive overview of recent advancements in organic fluorimetric and colorimetric detection of Co2+, emphasizing innovative sensing strategies, emerging materials, and detection mechanisms. It critically discusses key challenges, including sensitivity limitations, selectivity in complex environments, and stability concerns, while offering insights into future research directions aimed at enhancing detection performance, broadening applicability, and integrating advanced analytical technologies for real-world applications.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-19"},"PeriodicalIF":4.2,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Liquid Biopsy-Based Smart Sensors for Ovarian Cancer Detection. 基于液体活检的卵巢癌检测智能传感器。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-07-16 DOI: 10.1080/10408347.2025.2530177

Pallavi Kumari, Anupama Aiyar, Shweta Dang

{"title":"Liquid Biopsy-Based Smart Sensors for Ovarian Cancer Detection.","authors":"Pallavi Kumari, Anupama Aiyar, Shweta Dang","doi":"10.1080/10408347.2025.2530177","DOIUrl":"https://doi.org/10.1080/10408347.2025.2530177","url":null,"abstract":"Ovarian cancer is one of the most aggressive gynecologic malignancies, with a vast majority of patients diagnosed at advanced stages owing to the lack of available early detection methods. Liquid biopsy, a noninvasive method for detecting circulating biomarkers such as circulating tumor cells (CTCs), cell-free DNA (cfDNA), exosomes, and a wide range of non-coding RNAs (including microRNAs, long non-coding RNAs, and circular RNAs), enables the detection of ovarian cancer using composite biomarker panels tailored for disease specificity. Liquid biopsy-based diagnostics have also made a significant leap forward in terms of sensitivity, specificity, and real-time monitoring due to integration of smart sensor technology. To meet the challenge of sensitivity, highly specific bioelectrical and electrochemical, optical as well and nanomaterial-based sensors have been developed to detect ovarian cancer biomarkers within minutes that are cost-effective and scalable. The progress of Lab-on-Chip technologies, nano-bio sensing systems, and artificial intelligence-driven diagnostic models have further redefined this field by increasing biomarker detection and facilitating clinical decision-making efficiencies. This review discusses the state-of-the-art of liquid biopsy in smart sensors, their fundamentals, and the breakthroughs of these technologies of interest for ovarian cancer detection. Moreover, both clinical utility and regulatory hurdles of this biosensing will be interpreted to decipher the translational readiness for broad clinical application. The smart biosensors will continue to evolve, determining the future of ovarian cancer diagnostics by providing early detection and personalized treatment options and quality of life for patients.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-16"},"PeriodicalIF":4.2,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emetine: Advances in Pharmacology, Toxicology, and Chromatographic Approaches. 艾美汀：药理学、毒理学和色谱方法的进展。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-07-15 DOI: 10.1080/10408347.2025.2529458

Weldejeworgis Gebrehiwot, Kenan Can Tok, Jamilah S Alkhashi, Oladapo Bakare, Mehmet Gumustas

{"title":"Emetine: Advances in Pharmacology, Toxicology, and Chromatographic Approaches.","authors":"Weldejeworgis Gebrehiwot, Kenan Can Tok, Jamilah S Alkhashi, Oladapo Bakare, Mehmet Gumustas","doi":"10.1080/10408347.2025.2529458","DOIUrl":"https://doi.org/10.1080/10408347.2025.2529458","url":null,"abstract":"Emetine, derived from Psychotria ipecacuanha, is a tetrahydroisoquinoline alkaloid known for its diverse pharmacological activities, making it a versatile candidate for therapeutic applications. It has demonstrated efficacy against various conditions, including cancer and other viral infections by disrupting viral protein synthesis and assembly, particularly against influenza and Ebola viruses. Despite its therapeutic potential, concerns about cardiotoxicity have limited its clinical use, prompting exploration into safer administration routes and novel formulations. Emetine's anti-cancer properties involve inhibiting the Wnt/β-catenin pathway in breast cancer cells and showing promise in treating pulmonary arterial hypertension by suppressing pulmonary artery smooth muscle cell proliferation. Liquid chromatography plays a pivotal role in characterizing and quantifying emetine and related compounds, crucial for drug development and quality control by enhancing detection sensitivity and specificity in samples. Addressing concerns over emetine's toxicity novel approaches like pH-dependent prodrugs and targeted delivery systems are under development to improve safety and efficacy profiles. This review consolidates current knowledge on emetine's pharmacology and the essential role of analytical methodologies in its study and development. It focuses on recent advancements from 1979 to 2024 in liquid chromatography analysis and applications of emetine and its derivatives in drug research, health sciences, as well as forensic purposes.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-14"},"PeriodicalIF":4.2,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Organic Explosives in Plants and Soil: Accumulation, Analysis and Risk assessment - A Review. 植物和土壤中的有机炸药：积累、分析和风险评估综述。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-07-14 DOI: 10.1080/10408347.2025.2517797

Inga Sowik, Lena Ruzik

{"title":"Organic Explosives in Plants and Soil: Accumulation, Analysis and Risk assessment - A Review.","authors":"Inga Sowik, Lena Ruzik","doi":"10.1080/10408347.2025.2517797","DOIUrl":"https://doi.org/10.1080/10408347.2025.2517797","url":null,"abstract":"Explosives originating from military operations, industrial processes, and armed conflicts have become persistent environmental contaminants, with nitroaromatic and nitroheterocyclic compounds such as 2,4,6-trinitrotoluene (TNT) and 1,3,5-trinitro-1,3,5-triazinane (RDX) among the most hazardous. These substances can accumulate in soil and water at high concentrations and undergo chemical transformation, degradation, and plant uptake, posing serious risks to ecosystems and human health. While the analysis of explosives in water and soil has advanced significantly-primarily through techniques like LC-MS/MS-there remains a critical gap in understanding their behavior and metabolism in plant matrices. This review critically examines current analytical methodologies for detecting explosives and their transformation products in environmental samples, with special emphasis on soil and plant systems. We discuss the strengths and limitations of extraction techniques such as ultrasound-assisted extraction, pressurized liquid extraction, and accelerated solvent extraction, as well as challenges posed by matrix complexity and analyte instability. Instrumental techniques including LC-MS/MS, GC-ECD, MALDI-TOF, and emerging ambient ionization mass spectrometry approaches are evaluated in terms of sensitivity, selectivity, and field applicability. Additionally, this review highlights gaps in regulatory frameworks concerning permissible residue levels in plants and proposes future directions for standardizing methods and improving risk assessment protocols. By focusing on plant contamination-an often-overlooked yet crucial link in environmental exposure pathways-this work underscores the urgent need for integrated analytical strategies to monitor, manage, and mitigate the environmental and health impacts of explosive residues.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-14"},"PeriodicalIF":4.2,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of Ternary Deep Eutectic Solvent in Liquid-Phase Microextraction Techniques. 三元深共晶溶剂在液相微萃取技术中的应用。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-07-10 DOI: 10.1080/10408347.2025.2527758

Enoch Olvera-Ureña, Begoña Aguilar-Perez, Karen A Escamilla-Lara, Jorge Lopez-Tellez, Sandra Ramirez-Montes, Jose A Rodriguez

{"title":"Application of Ternary Deep Eutectic Solvent in Liquid-Phase Microextraction Techniques.","authors":"Enoch Olvera-Ureña, Begoña Aguilar-Perez, Karen A Escamilla-Lara, Jorge Lopez-Tellez, Sandra Ramirez-Montes, Jose A Rodriguez","doi":"10.1080/10408347.2025.2527758","DOIUrl":"https://doi.org/10.1080/10408347.2025.2527758","url":null,"abstract":"In recent years, deep eutectic solvents (DESs) have experienced widespread growth due to their potential use as \"green solvents\" replacing traditional organic solvents. DESs present important advantages such as easy preparation, high affinity, low toxicity and accessibility of their components. Therefore, they have been applied as extracting agents in liquid phase microextraction techniques. Despite the DESs advantages, some limitations have been described related to their solubility, viscosity, selectivity and stability, consequently, an alternative described is binary DESs incorporation of a third component (ternary deep eutectic solvents) have been developed as an alternative. This new type of solvents improves some physical and chemical characteristics as well as extraction efficiency and selectivity, besides to exhibit good stability in polar or nonpolar matrices, high ratio dispersion and separation from extraction media, good selectivity and affinity toward various compounds. This review classifies ternary DESs based on the components used in their synthesis, as hydrophilic ternary DESs, hydrophobic ternary DESs, magnetic ternary DESs, supramolecular ternary DESs, and polymeric ternary DESs and their sub-classifications. Emerging trends in the development of ternary DES, including the interaction mechanisms for the extraction process, their application in various matrices, and the results obtained for different target compounds, are described and discussed.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-25"},"PeriodicalIF":4.2,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comprehensive Review of Terahertz Time-Domain Spectroscopy for Agri-Food Safety Detection: Enhanced Sensing Performance Through Multidisciplinary Technology Integration. 太赫兹时域光谱用于农业食品安全检测的综合综述：通过多学科技术集成提高传感性能。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-07-09 DOI: 10.1080/10408347.2025.2527748

Lintong Zhang, Shuhui Wang, Wangjincheng Yang, Xinze Liu, Zenghui Wei, Alwaseela Abdalla, Jiachen Zhang, Xiangzeng Kong, Fangfang Qu

{"title":"A Comprehensive Review of Terahertz Time-Domain Spectroscopy for Agri-Food Safety Detection: Enhanced Sensing Performance Through Multidisciplinary Technology Integration.","authors":"Lintong Zhang, Shuhui Wang, Wangjincheng Yang, Xinze Liu, Zenghui Wei, Alwaseela Abdalla, Jiachen Zhang, Xiangzeng Kong, Fangfang Qu","doi":"10.1080/10408347.2025.2527748","DOIUrl":"https://doi.org/10.1080/10408347.2025.2527748","url":null,"abstract":"The development of efficient and accurate methods for detecting contamination in agri-foods is critical for ensuring food safety. Terahertz time-domain spectroscopy (THz-TDS), distinguished by its unique spectral characteristics and nondestructive detection capabilities, emerges as a powerful tool for analyzing agri-food safety. This review systematically examines the integration of THz-TDS with frontier technologies (machine learning [ML], metamaterials [MM], microfluidics [MF], and functional nanomaterials [FN]) to enhance detection capabilities. The article delves into the advancements achieved in detecting physical, chemical, and microbial contaminants in agri-food over the past five years (2020-2024) through the integration of THz-TDS with these frontier technologies. Based on the current state of research, this article summarizes the challenges and prospects of THz-TDS with interdisciplinary integration technologies in applications. To advance THz-TDS for agri-food safety monitoring, multidisciplinary integration is required. ML is critical for deciphering complex THz spectral datasets, while MM play a pivotal role in amplifying analyte-specific spectral signatures. FN leverage their potential high-throughput specific adsorption and plasmonic resonance properties to enhance detection sensitivity and specificity. The MF systems can reduce absorption induced by water. This review aims to provide new insights into the multidisciplinary convergence to propel THz-TDS toward transformative agri-food safety applications.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-22"},"PeriodicalIF":4.2,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144590629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Smart Organic Probes and Their Applications: Sequential Fluorometric and Colorimetric Sensing of Cu²⁺ and CN^- Ions: A Review (2018-2025). 智能有机探针及其应用：Cu2+和CN-离子的顺序荧光和比色传感：综述（2018-2025）。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-07-07 DOI: 10.1080/10408347.2025.2527761

Jari S Algethami

{"title":"Smart Organic Probes and Their Applications: Sequential Fluorometric and Colorimetric Sensing of Cu2+ and CN- Ions: A Review (2018-2025).","authors":"Jari S Algethami","doi":"10.1080/10408347.2025.2527761","DOIUrl":"https://doi.org/10.1080/10408347.2025.2527761","url":null,"abstract":"The detection of Cu2+ and CN- ions is of significant importance due to their crucial roles in biological and environmental systems. While CN- is widely utilized in industrial applications, its high toxicity poses severe risks to human health and the environment, necessitating precise monitoring. Similarly, Cu2+, an essential trace element, becomes hazardous at excessive concentrations, leading to liver damage, cardiovascular diseases, and ecological toxicity. Dual-channel sensors that employ both colorimetric and fluorometric responses have gained attention for their ability to detect multiple analytes simultaneously with high specificity, cost-effectiveness, and operational simplicity. This review highlights recent advancements (2018-2025) in smart organic probes for sequential fluorometric and colorimetric sensing of Cu2+ and CN- ions. Various sensing mechanisms, including deprotonation, coordination, and addition reactions, have been explored to achieve selective recognition. The challenges associated with interference from other metal ions, solubility issues, and real-world applicability are critically analyzed. The development of multi-target sensors is emphasized, showing their potential for real-time environmental monitoring, medical diagnostics, and industrial safety applications. Future perspectives focus on improving probe performance through structural modifications, enhancing water solubility, and integrating smart materials for portable sensing platforms.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-16"},"PeriodicalIF":4.2,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trends and Innovations in Tools for Processing Chromatographic Data Using Mass Spectrometry Detection: A Systematic Review. 使用质谱检测处理色谱数据的工具的趋势和创新：系统综述。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2025-07-06 DOI: 10.1080/10408347.2025.2528134

Jelmir Craveiro de Andrade, Gislaine Natiele Dos Santos Costa, Celeste Yara Dos Santos Siqueira, Carlos Alberto Carbonezi, Regina Binotto, Vinicius Kartnaller

{"title":"Trends and Innovations in Tools for Processing Chromatographic Data Using Mass Spectrometry Detection: A Systematic Review.","authors":"Jelmir Craveiro de Andrade, Gislaine Natiele Dos Santos Costa, Celeste Yara Dos Santos Siqueira, Carlos Alberto Carbonezi, Regina Binotto, Vinicius Kartnaller","doi":"10.1080/10408347.2025.2528134","DOIUrl":"https://doi.org/10.1080/10408347.2025.2528134","url":null,"abstract":"Chromatographic data processing represents an increasing challenge in analytical science, particularly due to the complexity of samples and the large volume of data generated by chromatographic techniques coupled with mass spectrometry (MS). This paper presents a systematic review of technological innovations over the last six years in the development of computational tools for processing these data. The review follows the PRISMA protocol, with a search conducted across five databases (SciFinder, Scopus, Web of Science, Embase, and ScienceDirect), utilizing strategies based on indexed descriptors and Boolean combinations. Thirty-three studies were selected that met the criteria of originality, applicability, and innovation in analytical tools. The results reveal significant advancements in algorithms for peak detection, alignment, and deconvolution, with an emphasis on machine learning, deep learning, and multivariate resolution approaches. Tools such as DeepResolution, SeA-M2Net, SLAW, QPMASS, autoGCMSDataAnal, and AntDAS demonstrate automation, scalability, and higher accuracy in critical tasks such as noise filtering, baseline correction, and compound identification. The analysis also highlights the progress of open-source software, which promotes greater access and interoperability. Although challenges such as the need for annotated data and standardization remain, recent advancements signal a shift toward more robust, accessible, and adaptable solutions for chromatographic data processing, expanding the potential of analyses across various scientific and industrial contexts. In this review, 'peak deconvolution' refers to separating co-eluting chromatographic signals, while 'spectral deconvolution' denotes reconstructing pure MS/MS spectra from mixed fragments.\"","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-20"},"PeriodicalIF":4.2,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144574980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0