Critical reviews in analytical chemistry最新文献_第10页

Chromatographic Methods and Sample Pretreatment Techniques for Aldehydes, Biogenic Amine, and Carboxylic Acids in Food Samples. 食品样品中醛类、生物胺和羧酸的色谱法和样品预处理技术。

IF 4.2 2区化学

Critical reviews in analytical chemistry Pub Date : 2024-06-20 DOI: 10.1080/10408347.2024.2367232

Raneen Albarri, Hümeyra Funda Vardara, Selen Al, Armağan Önal

{"title":"Chromatographic Methods and Sample Pretreatment Techniques for Aldehydes, Biogenic Amine, and Carboxylic Acids in Food Samples.","authors":"Raneen Albarri, Hümeyra Funda Vardara, Selen Al, Armağan Önal","doi":"10.1080/10408347.2024.2367232","DOIUrl":"https://doi.org/10.1080/10408347.2024.2367232","url":null,"abstract":"This review paper critically examines the current state of research concerning the analysis and derivatization of aldehyde, aromatic hydrocarbons and carboxylic acids components in foods and drinks samples, with a specific focus on the application of Chromatographic techniques. These diverse components, as vital contributors to the sensory attributes of food, necessitate accurate and sensitive analytical methods for their identification and quantification, which is crucial for ensuring food safety and compliance with regulatory standards. In this paper, High-Performance Liquid Chromatography (HPLC) and Gas Chromatographic (GC) methods for the separation, identification, and quantification of aldehydes in complex food matrices were reviewed. In addition, the review explores derivatization strategies employed to enhance the detectability and stability of aldehydes during chromatographic analysis. Derivatization methods, when applied judiciously, improve separation efficiency and increase detection sensitivity, thereby ensuring a more accurate and reliable quantification of aldehyde aromatic hydrocarbons and carboxylic acids species in food samples. Furthermore, methodological aspects encompassing sample preparation, chromatographic separation, and derivatization techniques are discussed. Validation was carried out in term of limit of detections are highlighted as crucial elements in achieving accurate quantification of compounds content. The discussion presented by emphasizing the significance of the combined HPLC and GC chromatography methods, along with derivatization strategies, in advancing the analytical capabilities within the realm of food science.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-22"},"PeriodicalIF":4.2,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mass Spectrometry Imaging Techniques: Non-Ambient and Ambient Ionization Approaches. 质谱成像技术：非环境和环境电离方法。

IF 5 2区化学

Critical reviews in analytical chemistry Pub Date : 2024-06-18 DOI: 10.1080/10408347.2024.2362703

Shundi Hu, Ahsan Habib, Wei Xiong, La Chen, Lei Bi, Luhong Wen

{"title":"Mass Spectrometry Imaging Techniques: Non-Ambient and Ambient Ionization Approaches.","authors":"Shundi Hu, Ahsan Habib, Wei Xiong, La Chen, Lei Bi, Luhong Wen","doi":"10.1080/10408347.2024.2362703","DOIUrl":"https://doi.org/10.1080/10408347.2024.2362703","url":null,"abstract":"Molecular information can be acquired from sample surfaces in real time using a revolutionary molecular imaging technique called mass spectrometry imaging (MSI). The technique can concurrently provide high spatial resolution information on the spatial distribution and relative proportion of many different compounds. Thus, many scientists have been drawn to the innovative capabilities of the MSI approach, leading to significant focus in various fields during the past few decades. This review describes the sampling protocol, working principle and applications of a few non-ambient and ambient ionization mass spectrometry imaging techniques. The non-ambient techniques include secondary ionization mass spectrometry and matrix-assisted laser desorption ionization, while the ambient techniques include desorption electrospray ionization, laser ablation electrospray ionization, probe electro-spray ionization, desorption atmospheric pressure photo-ionization and femtosecond laser desorption ionization. The review additionally addresses the advantages and disadvantages of ambient and non-ambient MSI techniques in relation to their suitability, particularly for biological samples used in tissue diagnostics. Last but not least, suggestions and conclusions are made regarding the challenges and future prospects of MSI.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-54"},"PeriodicalIF":5.0,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141418286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancements in Biosensors for Point-of-Care Testing of Nucleic Acid. 核酸床旁检测生物传感器的进展。

IF 5 2区化学

Critical reviews in analytical chemistry Pub Date : 2024-06-18 DOI: 10.1080/10408347.2024.2366943

Tao Ming, Tingting Lan, Mingxing Yu, Shuhan Cheng, Xu Duan, Hong Wang, Juan Deng, Deling Kong, Shuang Yang, Zhongyang Shen

{"title":"Advancements in Biosensors for Point-of-Care Testing of Nucleic Acid.","authors":"Tao Ming, Tingting Lan, Mingxing Yu, Shuhan Cheng, Xu Duan, Hong Wang, Juan Deng, Deling Kong, Shuang Yang, Zhongyang Shen","doi":"10.1080/10408347.2024.2366943","DOIUrl":"https://doi.org/10.1080/10408347.2024.2366943","url":null,"abstract":"Rapid, low-cost and high-specific diagnosis based on nucleic acid detection is pivotal in both detecting and controlling various infectious diseases, effectively curbing their spread. Moreover, the analysis of circulating DNA in whole blood has emerged as a promising noninvasive strategy for cancer diagnosis and monitoring. Although traditional nucleic acid detection methods are reliable, their time-consuming and intricate processes restrict their application in rapid field assays. Consequently, an urgent emphasis on point-of-care testing (POCT) of nucleic acids has arisen. POCT enables timely and efficient detection of specific sequences, acting as a deterrent against infection sources and potential tumor threats. To address this imperative need, it is essential to consolidate key aspects and chart future directions in POCT biosensors development. This review aims to provide an exhaustive and meticulous analysis of recent advancements in POCT devices for nucleic acid diagnosis. It will comprehensively compare these devices across crucial dimensions, encompassing their integrated structures, the synthesized nanomaterials harnessed, and the sophisticated detection principles employed. By conducting a rigorous evaluation of the current research landscape, this review will not only spotlight achievements but also identify limitations, offering valuable insights into the future trajectory of nucleic acid POCT biosensors. Through this comprehensive analysis, the review aspires to serve as an indispensable guide for fostering the development of more potent biosensors, consequently fostering precise and efficient POCT applications for nucleic acids.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-16"},"PeriodicalIF":5.0,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141418285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in Chromatographic and Mass Spectrometric Techniques for Analyzing Reducing Monosaccharides and Their Phosphates in Biological Samples. 分析生物样本中还原单糖及其磷酸盐的色谱和质谱技术的进展。

IF 5 2区化学

Critical reviews in analytical chemistry Pub Date : 2024-06-10 DOI: 10.1080/10408347.2024.2364232

Jiaqi Chen, Yifeng Lou, Yuwei Liu, Bowen Deng, Zheng Zhu, Sen Yang, Di Chen

{"title":"Advances in Chromatographic and Mass Spectrometric Techniques for Analyzing Reducing Monosaccharides and Their Phosphates in Biological Samples.","authors":"Jiaqi Chen, Yifeng Lou, Yuwei Liu, Bowen Deng, Zheng Zhu, Sen Yang, Di Chen","doi":"10.1080/10408347.2024.2364232","DOIUrl":"https://doi.org/10.1080/10408347.2024.2364232","url":null,"abstract":"Reducing monosaccharides and their phosphates are critical metabolites in the central carbon metabolism pathway of living organisms. Variations in their content can indicate abnormalities in metabolic pathways and the onset of certain diseases, necessitating their analysis and detection. Reducing monosaccharides and their phosphates exhibit significant variations in content within biological samples and are present in many isomers, which makes the accurate quantification of reducing monosaccharides and their phosphates in biological samples a challenging task. Various analytical methods such as spectroscopy, fluorescence detection, colorimetry, nuclear magnetic resonance spectroscopy, sensor-based techniques, chromatography, and mass spectrometry are employed to detect monosaccharides and phosphates. In comparison, chromatography and mass spectrometry are highly favored for their ability to simultaneously analyze multiple components and their high sensitivity and selectivity. This review thoroughly evaluates the current chromatographic and mass spectrometric methods used for detecting reducing monosaccharides and their phosphates from 2013 to 2023, highlighting their efficacy and the advancements in these analytical technologies.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-23"},"PeriodicalIF":5.0,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent Advances in Organic Small-Molecule Fluorescent Probes Based on Dicyanoisophorone Derivatives. 基于二氰异佛尔酮衍生物的有机小分子荧光探针的最新进展。

IF 5 2区化学

Critical reviews in analytical chemistry Pub Date : 2024-06-05 DOI: 10.1080/10408347.2024.2354328

Liqiang Yan, Liting Tang, Xiongzhi Wu, Lin Li

{"title":"Recent Advances in Organic Small-Molecule Fluorescent Probes Based on Dicyanoisophorone Derivatives.","authors":"Liqiang Yan, Liting Tang, Xiongzhi Wu, Lin Li","doi":"10.1080/10408347.2024.2354328","DOIUrl":"https://doi.org/10.1080/10408347.2024.2354328","url":null,"abstract":"Fluorescent probe technology holds great promise in the fields of environmental monitoring and clinical diagnosis due to its inherent advantages, including easy operation, reliable detection signals, fast analysis speed, and in situ imaging capabilities. In recent years, a wide range of fluorescent probes based on diverse fluorophores have been developed for the analysis and detection of various analytes, yielding significant achievement. Among these fluorophores, the dicyanoisophorone-based fluorophores have garnered significant attention. Dicyanoisoporone exhibits minimal fluorescence, yet possesses a robust electron-withdrawing capability, rendering it suitable for constructing of D-π-A structured fluorophores. Leveraging the intramolecular charge transfer (ICT) effect, such fluorophores exhibit near-infrared (NIR) fluorescence emission with a large Stokes shift, thereby offering remarkable advantages in the design and development of NIR fluorescence probes. This review article primarily focus on small-molecule dicyanoisoporone-based probes from the past two years, elucidating their design strategies, detection performances, and applications. Additionally, we summarize current challenges while predicting future directions to provide valuable references for developing novel and advanced fluorescence probes based on dicyanoisoporone derivatives.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-28"},"PeriodicalIF":5.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Label-Free Field Effect Transistors (FETs) for Fabrication of Point-of-Care (POC) Biomedical Detection Probes. 用于制造护理点 (POC) 生物医学检测探头的无标签场效应晶体管 (FET)。

IF 5 2区化学

Critical reviews in analytical chemistry Pub Date : 2024-06-03 DOI: 10.1080/10408347.2024.2356842

Zena Kadhim Al-Younis, Yasir Qasim Almajidi, Sofiene Mansouri, Irfan Ahmad, Umid Turdialiyev, Hashem O Alsaab, Montather F Ramadan, S K Joshi, Ahmed Hussien Alawadi, Ali Alsaalamy

{"title":"Label-Free Field Effect Transistors (FETs) for Fabrication of Point-of-Care (POC) Biomedical Detection Probes.","authors":"Zena Kadhim Al-Younis, Yasir Qasim Almajidi, Sofiene Mansouri, Irfan Ahmad, Umid Turdialiyev, Hashem O Alsaab, Montather F Ramadan, S K Joshi, Ahmed Hussien Alawadi, Ali Alsaalamy","doi":"10.1080/10408347.2024.2356842","DOIUrl":"https://doi.org/10.1080/10408347.2024.2356842","url":null,"abstract":"Field effect transistors (FETs)-based detection probes are powerful platforms for quantification in biological media due to their sensitivity, ease of miniaturization, and ability to function in biological media. Especially, FET-based platforms have been utilized as promising probes for label-free detections with the potential for use in real-time monitoring. The integration of new materials in the FET-based probe enhances the analytical performance of the developed probes by increasing the active surface area, rejecting interfering agents, and providing the possibility for surface modification. Furthermore, the use of new materials eliminates the need for traditional labeling techniques, providing rapid and cost-effective detection of biological analytes. This review discusses the application of materials in the development of FET-based label-free systems for point-of-care (POC) analysis of different biomedical analytes from 2018 to 2024. The mechanism of action of the reported probes is discussed, as well as their pros and cons were also investigated. Also, the possible challenges and potential for the fabrication of commercial devices or methods for use in clinics were discussed.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-22"},"PeriodicalIF":5.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141198784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent Trends and Perspectives in Single-Entity Electrochemistry: A Review with Focus on a Water Splitting Reaction. 单实体电化学的最新趋势和前景：以水分离反应为重点的综述。

IF 5 2区化学

Critical reviews in analytical chemistry Pub Date : 2024-06-03 DOI: 10.1080/10408347.2024.2358492

Gowrisankar Aruchamy, Byung-Kwon Kim

{"title":"Recent Trends and Perspectives in Single-Entity Electrochemistry: A Review with Focus on a Water Splitting Reaction.","authors":"Gowrisankar Aruchamy, Byung-Kwon Kim","doi":"10.1080/10408347.2024.2358492","DOIUrl":"https://doi.org/10.1080/10408347.2024.2358492","url":null,"abstract":"Electrochemical measurements involving single nanoparticles have attracted considerable research attention. In recent years, various studies have been conducted on single-entity electrochemistry (SEE) for the in-depth analyses of catalytic reactions. Although, several electrocatalysts have been developed for H2 energy production, designing innovative electrocatalysts for this purpose remains a challenging task. Stochastic collision electrochemistry is gaining increased attention because it has led to new findings in the SEE field. Importantly, it facilitates establishing structure activity relationships for electrocatalysts by monitoring transient signals. This article reviews the recent achievements related to hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) using different electrocatalysts at the nanoscale level. In particular, it discusses the electrocatalytic activities of noble metal nanoparticles, including Ag, Au, Pt, and Pd nanoparticles, at the single-particle level. Because heterogeneity is a key factor affecting the catalytic activity of nanostructures, our work focuses on the influence of heterogeneities in catalytic materials on the OER and HER activities. These results may help to achieve a better understanding of the fundamental processes involved in the water splitting reaction.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-17"},"PeriodicalIF":5.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141237325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cyclodextrin Functionalized Ionic Liquids: Synthesis and Application in Analytical Chemistry. 环糊精功能化离子液体：环糊精功能化离子液体：合成及在分析化学中的应用》。

IF 5 2区化学

Critical reviews in analytical chemistry Pub Date : 2024-05-16 DOI: 10.1080/10408347.2024.2351815

Ayushi Aggarwal, Harish Kumar Chopra

{"title":"Cyclodextrin Functionalized Ionic Liquids: Synthesis and Application in Analytical Chemistry.","authors":"Ayushi Aggarwal, Harish Kumar Chopra","doi":"10.1080/10408347.2024.2351815","DOIUrl":"https://doi.org/10.1080/10408347.2024.2351815","url":null,"abstract":"Cyclodextrins belong to a class of cyclic oligosaccharides composing of α-(1,4) linked glucopyranose subunits having a torus-like macro ring shape. Cyclodextrins based materials find a wide range of applications in separation technology due to their unique property to differentiate between enantiomers, positional isomers and functional groups. Conversely, ionic liquids are the non-molecular compounds composed of different anion and cations with low melting point making them a designer and greener solvents. Because of their fascinating properties, the combined effect of cyclodextrin and ionic liquids as cyclodextrin functionalized ionic liquids (CDILs) have nowadays led to an excellent development for their utilization in the area of analytical chemistry. This review focuses mainly on the synthesis of cyclodextrin functionalized ionic liquids and their application in separation techniques like capillary electrophoresis (CE), high-performance liquid chromatography (HPLC) and gas chromatography (GC). The nature of the interactions between CDILs and analytes have also been highlighted in this review.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-26"},"PeriodicalIF":5.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140944258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent Advancements in Molecularly Imprinted Polymers Based Aptasensors: Critical Role of Nanomaterials for the Efficient Food Safety Analysis. 基于分子印迹聚合物的光电传感器的最新进展：纳米材料在高效食品安全分析中的关键作用。

IF 5 2区化学

Critical reviews in analytical chemistry Pub Date : 2024-05-16 DOI: 10.1080/10408347.2024.2351826

Sofiene Mansouri

{"title":"Recent Advancements in Molecularly Imprinted Polymers Based Aptasensors: Critical Role of Nanomaterials for the Efficient Food Safety Analysis.","authors":"Sofiene Mansouri","doi":"10.1080/10408347.2024.2351826","DOIUrl":"https://doi.org/10.1080/10408347.2024.2351826","url":null,"abstract":"Biosensors are being studied extensively for their ability to detect and analyze molecules. There has been a growing interest in combining molecular imprinted polymers (MIPs) and aptamers to create hybrid recognition elements that offer advantages such as target binding, sensitivity, selectivity, and stability. These hybrid elements have been successfully used in identifying a wide range of analytes in food samples. However, the application of MIP-based aptasensors in different sensing approaches is still challenging due to the low conductivity of MIPs-aptamers and limited adsorption capacity of MIPs. To address these limitations, researchers have been exploring the use of nanomaterials (NMs) to design efficient multiple-recognition systems that exploit the synergies between aptamers and MIPs. These hybrid systems can enhance the sensitivity and selectivity of MIP-based aptasensors in quantifying analytical samples. This review provides a comprehensive overview of recent advancements in the field of MIP-based aptasensors. It also introduces technologies that combine MIPs and aptamers to achieve higher sensitivity and selectivity in quantifying analytical samples. The review also highlights potential future trends and practical approaches that can be employed to address the limitations of MIP-based aptasensors, including the use of new NMs, the development of new fabrication techniques, and the integration of MIP-based aptasensors with other analytical tools.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-16"},"PeriodicalIF":5.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140955881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrochemical Sensors and Biosensors for Identification of Viruses: A Critical Review. 用于识别病毒的电化学传感器和生物传感器：批判性评论。

IF 5 2区化学

Critical reviews in analytical chemistry Pub Date : 2024-05-16 DOI: 10.1080/10408347.2024.2343853

Bozena Hosnedlova, Julia Werle, Jana Cepova, Vedha Hari B Narayanan, Lenka Vyslouzilova, Carlos Fernandez, Arli Aditya Parikesit, Marta Kepinska, Eva Klapkova, Karel Kotaska, Olga Stepankova, Geir Bjorklund, Richard Prusa, Rene Kizek

{"title":"Electrochemical Sensors and Biosensors for Identification of Viruses: A Critical Review.","authors":"Bozena Hosnedlova, Julia Werle, Jana Cepova, Vedha Hari B Narayanan, Lenka Vyslouzilova, Carlos Fernandez, Arli Aditya Parikesit, Marta Kepinska, Eva Klapkova, Karel Kotaska, Olga Stepankova, Geir Bjorklund, Richard Prusa, Rene Kizek","doi":"10.1080/10408347.2024.2343853","DOIUrl":"https://doi.org/10.1080/10408347.2024.2343853","url":null,"abstract":"Due to their life cycle, viruses can disrupt the metabolism of their hosts, causing diseases. If we want to disrupt their life cycle, it is necessary to identify their presence. For this purpose, it is possible to use several molecular-biological and bioanalytical methods. The reference selection was performed based on electronic databases (2020-2023). This review focused on electrochemical methods with high sensitivity and selectivity (53% voltammetry/amperometry, 33% impedance, and 12% other methods) which showed their great potential for detecting various viruses. Moreover, the aforementioned electrochemical methods have considerable potential to be applicable for care-point use as they are portable due to their miniaturizability and fast speed analysis (minutes to hours), and are relatively easy to interpret. A total of 2011 articles were found, of which 86 original papers were subsequently evaluated (the majority of which are focused on human pathogens, whereas articles dealing with plant pathogens are in the minority). Thirty-two species of viruses were included in the evaluation. It was found that most of the examined research studies (77%) used nanotechnological modifications. Other ones performed immunological (52%) or genetic analyses (43%) for virus detection. 5% of the reports used peptides to increase the method's sensitivity. When evaluable, 65% of the research studies had LOD values in the order of ng or nM. The vast majority (79%) of the studies represent proof of concept and possibilities with low application potential and a high need of further research experimental work.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-30"},"PeriodicalIF":5.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140955797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0