Mehdi Kheirollahpour, Nader Shokoufi, Mohsen Lotfi
{"title":"The Potential of Optical Technologies in Early Virus Detection; Prospects in Addressing Future Viral Outbreaks.","authors":"Mehdi Kheirollahpour, Nader Shokoufi, Mohsen Lotfi","doi":"10.1080/10408347.2025.2481406","DOIUrl":"10.1080/10408347.2025.2481406","url":null,"abstract":"<p><p>The urgent need for sensitive, rapid, and reliable diagnostic methodologies to control and prevent life-threatening pandemic infectious disease, such as COVID-19, remains a critical priority. Timely and on-site detection of viral pathogens is essential for effective disease management and mitigation of societal disruptions. Recent advancements in optical diagnostic methods have positioned them at the forefront of healthcare diagnostics, offering high sensitivity and specificity as viable alternatives to conventional techniques such as the Polymerase Chain Reaction (PCR), which often suffer from time delays and limited accessibility in resource-constrained environments. This review elucidates the potential of various optical diagnostic techniques, highlighting their advantages over traditional methods. It encompasses a range of optical modalities, including fluorescence-based approaches, Raman spectroscopy (RS), Plasmonic techniques (e.g., surface plasmon resonance (SPR), localized SPR, (LSPR), surface-enhanced Raman spectroscopy (SERS), and surface-enhanced fluorescence (SEF)), super resolution microscopies (SRMs), attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), and integrated platforms such as waveguides and molecularly imprinted polymer (MIP)-based biosensors. Additionally, the evolution of novel biosensors, particularly 5th and 6th generation biosensors, in healthcare and the challenges related to these technologies were discussed. This studies reviewed aims to advance the development of portable, sensitive, specific, and cost-effective point-of-care (POC) diagnostic devices for the rapid detection of viral pathogens.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-29"},"PeriodicalIF":4.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ebraheem Abdu Musad Saleh, Hiba M Saleem, Mohammed Asiri, Subasini Uthirapathy, Subbulakshmi Ganesan, Piyus Kumar Pathak, Rsk Sharma, Bhanu Juneja, Naher H S, Ayham Sameer Faaq
{"title":"A Review of Recent Trends in the Development of Analytical Methods for Useful Compounds and Contaminations in Fruits Juices.","authors":"Ebraheem Abdu Musad Saleh, Hiba M Saleem, Mohammed Asiri, Subasini Uthirapathy, Subbulakshmi Ganesan, Piyus Kumar Pathak, Rsk Sharma, Bhanu Juneja, Naher H S, Ayham Sameer Faaq","doi":"10.1080/10408347.2025.2477536","DOIUrl":"https://doi.org/10.1080/10408347.2025.2477536","url":null,"abstract":"<p><p>In modern lifestyles, the consumption of fruit juice is increasing among different societies. Many people consider fruit juices to be safe beverages with numerous health benefits for human bodies. Although fruit juices contain several useful compounds that can promote human health, there is a probability of both microbiological and non-microbiological contaminations in these juices. It is important to have reliable detection methods to analyze the useful and harmful compounds present in different fruit juices. In fruit juice industry, various analytical methods have been used for analyzing different parameters, contaminations, and useful compounds in fruit juices. However, some limitations restrict their application in this field. Biosensors, as newly emerging sensing approaches, have been developed in this field. The sensitivity, selectivity, portability, and accuracy are key considerations in developing biosensors for detection of contaminations and antioxidants. This was achieved by the application of bioreceptors, nanomaterials, and novel designed technologies. In this review, the role of different techniques, nanomaterials, and bioreceptors is reviewed for development new biosensors in terms of analyzing fruit juices. In addition, the future prospects and challenges are also examined.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-20"},"PeriodicalIF":4.2,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CRISPR/Cas System-Based Fluorescent Sensor for Analysis and Detection.","authors":"Huiru Niu, Lina Zou, Yanan Liu, Zheng Li, Huanyu Ren, Hao Liao, Xiaojing Zhang, Shanshan An, Fei Ren, Xiuhong Ge, Lang Cheng, Feiyan Yang, Hongzhi Pan, Shengzhong Rong, Dong Chang, Hongkun Ma","doi":"10.1080/10408347.2025.2481409","DOIUrl":"https://doi.org/10.1080/10408347.2025.2481409","url":null,"abstract":"<p><p>Fluorescent sensor is an important tool to reliaze qualitative or quantitative detection of target analyte based on the fluorescence principle. Clustered regularly interspaced short palindromic repeats/CRISPR-associated protein (CRISPR/Cas) has been utilized to develop as a precise, efficient, and highly sensitive molecular diagnostic tool due to its efficient targeting and gene editing ability. At present, CRISPR/Cas system-based fluorescent sensors have shown excellent performance in the field of analysis and detection, and have received widespread attention. Therefore, this paper reviews the mechanism of the CRISPR/Cas system, the characteristics of different Cas proteins, and the principle and characteristics of the fluorescent sensor, with a focus on summarizing the application of the CRISPR/Cas system-based fluorescent sensor for analysis and detection.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-16"},"PeriodicalIF":4.2,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Masoomeh Naseri, Ali Niazi, Atisa Yazdanipour, Kowsar Bagherzadeh
{"title":"Recent Advances in Electrochemical Aptasensors for Detection of Clinical and Veterinary Drugs.","authors":"Masoomeh Naseri, Ali Niazi, Atisa Yazdanipour, Kowsar Bagherzadeh","doi":"10.1080/10408347.2025.2469781","DOIUrl":"https://doi.org/10.1080/10408347.2025.2469781","url":null,"abstract":"<p><p>Nowadays, aptamer-based biosensors and electrochemical measurements represent one of the efficient tools for the detection of drugs in both medical and veterinary. Precise trace values analysis of chemicals, especially drugs, plays a crucial role in food and therapeutic safety evaluations that are often time-consuming and costly. Ultimately, accurate determination of therapeutic medications like antibiotics in food, environmental resources, and biological matrices is very important for protecting public health and drug monitoring (TDM) for effective treatment. This review highlights recent advancements in electrochemical aptasensors as an innovative approach offering high sensitivity, specificity, and rapid detection of clinical and veterinary drugs at lower costs. We provide a comprehensive overview of the advancements and discuss the challenges and prospects of electrochemical aptasensing in drug residue detection across various samples.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-15"},"PeriodicalIF":4.2,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anti-diabetic Biologicals: Exploring the Role of Different Analytical Techniques.","authors":"Zahid Yaseen, Mukesh Nandave, Lalit Sharma","doi":"10.1080/10408347.2025.2472793","DOIUrl":"https://doi.org/10.1080/10408347.2025.2472793","url":null,"abstract":"<p><p>Antidiabetic biologicals (ADBs) have revolutionized the treatment of diabetes mellitus, once considered incurable through conventional medicine. These biological products, derived from natural sources <i>via</i> extraction, semi-synthesis, or recombinant DNA technology, include insulin and its analogs, GLP-1 receptor agonists, amylin analogs, and the recently approved monoclonal antibody teplizumab. Regulatory authorities worldwide have established QC parameters outlined in pharmacopoeias, alongside analytical techniques to ensure their safety and efficacy. This review focuses on the analytical techniques used to assess QC parameters of ADBs, including chromatographic methods, spectroscopic techniques, capillary electrophoresis, immunoassays, and endotoxin testing. Key parameters such as identification, potency, purity, and impurity profiling are thoroughly examined. The paper provides a comprehensive and up-to-date compilation of QC requirements and methodologies, along with a detailed comparison of analytical techniques. In doing so, it highlights their advantages and limitations, offering valuable insights for researchers and regulatory professionals involved in selecting suitable methods for QC assessment and understanding the complexities of ADBs evaluation. Furthermore, the article discusses the paramount importance of QC and future perspectives, emphasizing the transition to advanced versions of current techniques driven by the need for efficiency and reliability in quality testing.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-22"},"PeriodicalIF":4.2,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Sofia Almeida, Paula Guedes de Pinho, Fernando Remião, Carla Fernandes
{"title":"Metabolomics as a Tool for Unraveling the Impact of Enantioselectivity in Cellular Metabolism.","authors":"Ana Sofia Almeida, Paula Guedes de Pinho, Fernando Remião, Carla Fernandes","doi":"10.1080/10408347.2025.2468926","DOIUrl":"https://doi.org/10.1080/10408347.2025.2468926","url":null,"abstract":"<p><p>Metabolomics is an emerging interdisciplinary field focused on the comprehensive analysis of all metabolites within biological samples, making it valuable for areas such as drug development, and environmental analysis. Many compounds, including pharmaceuticals and agrochemicals that have been extensively studied by metabolomics are chiral. The intrinsic chirality of biological targets can lead to a selective recognition of enantiomers resulting in distinct pharmacokinetic, pharmacodynamic and/or toxicological profiles (enantioselectivity). Given that metabolomics captures an instant snapshot of an organism's metabolic state, it serves as a powerful tool to investigate chiral compounds and understand enantioselective effects. Herein, a systematic compilation of scientific literature was performed and 48 enantioselectivity studies using metabolomics were selected. These studies revealed an increasing focus on chiral pesticides (77%), the use of animal models (59%), reliance on LC-MS techniques (52%), and predominantly untargeted approaches (83%). Enantioselective effects were described in most studies. This review describes significant advances in this emerging field and highlights the use of metabolomics to unravel the role of stereochemistry in cellular metabolism by the examination of enantiomer-specific metabolic effects. Furthermore, it elucidates enantioselectivity mechanism that can be further applied to other groups of chiral compounds.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-21"},"PeriodicalIF":4.2,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Statement of Retraction: Recent Progress in Aptamer-Functionalized Metal-Organic Frameworks-Based Optical and Electrochemical Sensors for Detection of Mycotoxins.","authors":"","doi":"10.1080/10408347.2024.2437855","DOIUrl":"https://doi.org/10.1080/10408347.2024.2437855","url":null,"abstract":"","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1"},"PeriodicalIF":4.2,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Statement of Retraction: Current Progress in Aptasensor for Ultra-Low Level Monitoring of Parkinson's Disease Biomarkers.","authors":"","doi":"10.1080/10408347.2024.2437859","DOIUrl":"https://doi.org/10.1080/10408347.2024.2437859","url":null,"abstract":"","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1"},"PeriodicalIF":4.2,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Statement of Retraction: Optical and Electrochemical Aptasensors Developed for the Detection of Alpha-Fetoprotein.","authors":"","doi":"10.1080/10408347.2024.2437857","DOIUrl":"https://doi.org/10.1080/10408347.2024.2437857","url":null,"abstract":"","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1"},"PeriodicalIF":4.2,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent Developments in Colorimetric and Fluorimetric Chemosensors for the Detection of Mn<sup>2+</sup> Ions: A Review (2010-2024).","authors":"Eid H Alosaimi","doi":"10.1080/10408347.2025.2460091","DOIUrl":"https://doi.org/10.1080/10408347.2025.2460091","url":null,"abstract":"<p><p>Manganese is an essential metal ion involved in various biological and environmental processes, but its excess can lead to toxicity, particularly affecting the nervous system. Therefore, developing selective and sensitive detection methods for Mn<sup>2+</sup> ions is of paramount importance. Colorimetric and fluorimetric chemosensors have emerged as promising tools for the detection of Mn<sup>2+</sup> due to their simplicity, cost-effectiveness, and real-time monitoring capabilities. This review discusses recent advances in the colorimetric and fluorimetric chemosensors that exhibit distinct color or fluorescence changes upon interaction with Mn<sup>2+</sup> ions. The review explores different organic and nanomaterials, focusing on their mechanisms of sensing, sensitivity, selectivity, and practical applications in environmental monitoring, healthcare, and food safety. The article also provides insights into future research directions aimed at overcoming these challenges, improving chemosensor performance, and expanding the applicability of colorimetric and fluorimetric chemosensors for Mn<sup>2+</sup> detection in diverse real-world scenarios.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-21"},"PeriodicalIF":4.2,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}