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18 F-FDG PET/CT Positive and 68 Ga-DOTA-Bombesin PET/CT Negative Focus of Benign Apocrine Metaplasia Mimicking Malignancy. 18F-FDG PET/CT阳性病灶和68Ga-DOTA-Bombesin PET/CT阴性病灶模拟恶性大汗腺化生。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-05-01 Epub Date: 2025-03-03 DOI: 10.1097/RLU.0000000000005709
Esra Arslan, Mehmet Can Baloğlu, İrem Aylin Özkan, Göksel Alçin, Elife Akgün, Tevfik Fikret Çermik
{"title":"18 F-FDG PET/CT Positive and 68 Ga-DOTA-Bombesin PET/CT Negative Focus of Benign Apocrine Metaplasia Mimicking Malignancy.","authors":"Esra Arslan, Mehmet Can Baloğlu, İrem Aylin Özkan, Göksel Alçin, Elife Akgün, Tevfik Fikret Çermik","doi":"10.1097/RLU.0000000000005709","DOIUrl":"10.1097/RLU.0000000000005709","url":null,"abstract":"<p><p>Gastrin-releasing peptide receptor (GRPR) is a promising agent for imaging and development of theranostic radioligands in estrogen receptor (ER)-positive luminal type breast cancer (BC) and may show expression not only in primary malignant lesions but also in lymph node metastases and distant organ metastases. We would like to present a lesion diagnosed as benign apocrine metaplasia in a 45-year-old woman diagnosed with BC, which was negative in 68 Ga-DOTA-Bombesin PET-CT and false positive in 18 F-FDG PET-CT imaging, within the scope of the ongoing study.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e300-e302"},"PeriodicalIF":9.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concomitant ATTR and AL Cardiac Amyloidosis With Matching 99m Tc-DPD Scintigraphy and 18 F-Flutemetamol PET/CT. 伴发ATTR和AL型心脏淀粉样变性伴99mTc-DPD显像和18f -氟替他莫PET/CT
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-05-01 Epub Date: 2025-02-24 DOI: 10.1097/RLU.0000000000005784
Joo Hyun O, Jong-Chan Youn, Eun Ji Han, Mi-Hyang Jung, Jung Yeon Lee, Sung-Soo Park, Yeoun Eun Sung, Chang-Ki Min
{"title":"Concomitant ATTR and AL Cardiac Amyloidosis With Matching 99m Tc-DPD Scintigraphy and 18 F-Flutemetamol PET/CT.","authors":"Joo Hyun O, Jong-Chan Youn, Eun Ji Han, Mi-Hyang Jung, Jung Yeon Lee, Sung-Soo Park, Yeoun Eun Sung, Chang-Ki Min","doi":"10.1097/RLU.0000000000005784","DOIUrl":"10.1097/RLU.0000000000005784","url":null,"abstract":"<p><p>Two distinct types of systemic amyloidosis-transthyretin (ATTR) and light chain (AL)-account for the majority of cardiac amyloidosis (CA), which have been considered mutually exclusive. Diagnostic confusion can arise when both proteins are identified from an amyloid deposit. We present a rare occurrence of histopathologically confirmed concomitant ATTR and AL CA captured on 99m Tc-3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) scan and 18 F-flutemetamol (FMM) PET/CT.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"460-461"},"PeriodicalIF":9.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
18 F-FDG PET/CT Revealed Bone Infarction as the Cause of Unexplained Fever. 18F-FDG PET/CT显示骨梗死是不明原因发热的原因。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-05-01 Epub Date: 2024-12-23 DOI: 10.1097/RLU.0000000000005637
Xueqi Chen, Qian Li, Zhanli Fu
{"title":"18 F-FDG PET/CT Revealed Bone Infarction as the Cause of Unexplained Fever.","authors":"Xueqi Chen, Qian Li, Zhanli Fu","doi":"10.1097/RLU.0000000000005637","DOIUrl":"10.1097/RLU.0000000000005637","url":null,"abstract":"<p><strong>Abstract: </strong>An 18 F-FDG PET/CT was conducted on a 44-year-old man with a history of dermatomyositis and avascular necrosis of left femoral head, due to a fever of unknown origin. The scan revealed patchy and cloudy high densities within the medullary cavities of bilateral distal femur and proximal tibia, exhibiting peripheral high 18 F-FDG avidity. Subsequent MRI confirmed bone infarction.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e305-e306"},"PeriodicalIF":9.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Walthard Cell Nests Leading to 18 F-FDG Increased Uptake of Fallopian Tube. Walthard细胞巢导致输卵管18F-FDG摄取增加。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-05-01 Epub Date: 2025-01-23 DOI: 10.1097/RLU.0000000000005682
Shufan Xu, Lei Ou, Xiaoliang Chen
{"title":"Walthard Cell Nests Leading to 18 F-FDG Increased Uptake of Fallopian Tube.","authors":"Shufan Xu, Lei Ou, Xiaoliang Chen","doi":"10.1097/RLU.0000000000005682","DOIUrl":"10.1097/RLU.0000000000005682","url":null,"abstract":"<p><strong>Abstract: </strong>We present 18 F-FDG PET/CT findings of fallopian tube with Walthard cell nests. The images revealed a thickening of the bilateral fallopian tubes with increased FDG uptake. Malignant tumor or tuberculosis of the fallopian tube was suspected. Histopathology suggested fallopian tube with Walthard cell nests.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"452-453"},"PeriodicalIF":9.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Significantly Elevated FDG Activity in Esophageal Inflammatory Myofibroblastic Tumor of a Pediatric Patient. 1例小儿食管炎性肌纤维母细胞瘤中FDG活性显著升高。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-05-01 Epub Date: 2025-01-23 DOI: 10.1097/RLU.0000000000005684
Xin Cheng, Liyan Xue, Lin Lin, Jing Li, Xuejuan Wang
{"title":"Significantly Elevated FDG Activity in Esophageal Inflammatory Myofibroblastic Tumor of a Pediatric Patient.","authors":"Xin Cheng, Liyan Xue, Lin Lin, Jing Li, Xuejuan Wang","doi":"10.1097/RLU.0000000000005684","DOIUrl":"10.1097/RLU.0000000000005684","url":null,"abstract":"<p><strong>Abstract: </strong>A 13-year-old girl presented with dysphagia underwent contrast-enhanced CT and endoscopy. The CT revealed cervical esophageal wall thickening with heterogeneous enhancement. Microscopic examination of the biopsy specimen suggested a possible mesenchymal tumor. She underwent an 18 F-FDG PET/CT scan for staging. The scan showed local thickening of the cervical esophageal wall with heterogeneous and significantly elevated FDG activity. Subsequent immunohistochemical staining and fluorescence in situ hybridization confirmed the diagnosis of esophageal inflammatory myofibroblastic tumor.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"464-465"},"PeriodicalIF":9.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Collagen Vascular Disease-Associated Interstitial Pneumonia With Accumulation of 18F-fluoroestradiol. 胶原血管病相关的间质性肺炎与18f -氟雌二醇的积累。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-05-01 Epub Date: 2025-04-07 DOI: 10.1097/RLU.0000000000005743
Sumika Yasumura, Kanae K Miyake, Yoichi Shimizu, Tomomi Nobashi, Yuji Nakamoto
{"title":"Collagen Vascular Disease-Associated Interstitial Pneumonia With Accumulation of 18F-fluoroestradiol.","authors":"Sumika Yasumura, Kanae K Miyake, Yoichi Shimizu, Tomomi Nobashi, Yuji Nakamoto","doi":"10.1097/RLU.0000000000005743","DOIUrl":"10.1097/RLU.0000000000005743","url":null,"abstract":"<p><p>18F-fluoroestradiol (18F-FES) is a PET radiotracer that binds to the estrogen receptor (ER) in the nucleus of ER-expressing cells and is increasingly used clinically in breast cancer patients to visualize ER expression in lesions. Although 18F-FES accumulation is generally specific, radiation-induced pneumonitis can produce false-positive results, but the underlying mechanisms remain largely unclear. Here, we report the case of a 72-year-old woman with known collagen vascular disease-associated interstitial pneumonia and the accumulation of 18F-FES on 18F-FES-PET/CT, which was conducted to investigate suspected recurrent breast cancer.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":"50 5","pages":"428-430"},"PeriodicalIF":9.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extrarenal Uptake of 99mTc-DMSA in Uterine Leiomyoma: From Misdiagnosis to Clarity With SPECT/CT Imaging. 子宫平滑肌瘤肾外摄取99mTc-DMSA：从误诊到SPECT/CT显像的澄清。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-05-01 Epub Date: 2025-04-07 DOI: 10.1097/RLU.0000000000005721
Mohammad Hadi Samadi, Pegah Sahafi, Haniye Elahifard, Bahram Memar, Somaye Barashki
{"title":"Extrarenal Uptake of 99mTc-DMSA in Uterine Leiomyoma: From Misdiagnosis to Clarity With SPECT/CT Imaging.","authors":"Mohammad Hadi Samadi, Pegah Sahafi, Haniye Elahifard, Bahram Memar, Somaye Barashki","doi":"10.1097/RLU.0000000000005721","DOIUrl":"10.1097/RLU.0000000000005721","url":null,"abstract":"<p><p>We present a DMSA renal scan finding in a 42-year-old woman with new flank pain. Ultrasonography revealed hydronephrosis and renal stones. A 99mTc-DMSA renal scan showed global cortical loss and multiple cortical defects in the left kidney, with an incidental large zone of uptake in the abdominopelvic region initially suspected as bladder. SPECT/CT imaging clarified this as a large leiomyoma which is proved in permanent pathology. This case highlights the importance of advanced imaging to distinguish physiological organs from tumoral masses and avoid misdiagnosis.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":"50 5","pages":"e317-e319"},"PeriodicalIF":9.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subcutaneous Infection With Snow Leopard Sign on 18 F-FDG PET/CT Mimicking Subcutaneous Panniculitis-Like T-Cell Lymphoma. 18F-FDG PET/CT模拟皮下泛膜炎样t细胞淋巴瘤伴有雪豹征象的皮下感染。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-05-01 Epub Date: 2025-01-20 DOI: 10.1097/RLU.0000000000005669
Xinyue Zheng, Tingting Zhang, Xiaofang Yan, Xinhui Su, Peipei Wang
{"title":"Subcutaneous Infection With Snow Leopard Sign on 18 F-FDG PET/CT Mimicking Subcutaneous Panniculitis-Like T-Cell Lymphoma.","authors":"Xinyue Zheng, Tingting Zhang, Xiaofang Yan, Xinhui Su, Peipei Wang","doi":"10.1097/RLU.0000000000005669","DOIUrl":"10.1097/RLU.0000000000005669","url":null,"abstract":"<p><strong>Abstract: </strong>A 37-year-old man presented with a 2-month history of fever of unknown origin and erythema rashes on the trunk and limbs. 18 F-FDG PET/CT revealed increased 18 F-FDG uptake in subcutaneous panniculitis, forming a snow leopard sign, along with enlarged lymph nodes, which suggested subcutaneous panniculitis-like T-cell lymphoma. However, skin biopsy indicated subcutaneous infection, and bone marrow biopsy revealed no abnormal lymphocytes. After anti-infection treatment, symptoms improved, leading to a final diagnosis of systemic infection. This case demonstrates how extensive subcutaneous infections on PET/CT could be misinterpreted as subcutaneous panniculitis-like T-cell lymphoma.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e310-e311"},"PeriodicalIF":9.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skull Base Metastasis of Uterine Carcinosarcoma Mimicking Primary Carcinoma of the Middle Ear. 模拟中耳原发癌的子宫癌肉瘤的颅底转移。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-05-01 Epub Date: 2025-01-23 DOI: 10.1097/RLU.0000000000005678
Yuxiang Wang, Yan Cui, Bulin Du, Xuena Li, Yaming Li
{"title":"Skull Base Metastasis of Uterine Carcinosarcoma Mimicking Primary Carcinoma of the Middle Ear.","authors":"Yuxiang Wang, Yan Cui, Bulin Du, Xuena Li, Yaming Li","doi":"10.1097/RLU.0000000000005678","DOIUrl":"10.1097/RLU.0000000000005678","url":null,"abstract":"<p><strong>Abstract: </strong>Uterine carcinosarcoma is a rare type of endometrial carcinoma with poor prognosis. A bone metastasis to the skull base is extremely scarce in uterine carcinosarcoma. A 54-year-old woman with uterine carcinosarcoma complained of right ear otorrhea and otalgia. 18 F-FDG PET/CT presented an increased FDG uptake at the right middle ear involving the mastoid process and external acoustic meatus. Primary carcinoma of the middle ear was considered according to clinical symptoms and PET manifestation. However, the skull base metastasis from uterine carcinosarcoma was pathologically confirmed. The rare metastasis from uterine carcinosarcoma should be differentiated from primary carcinoma of the middle ear.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"419-420"},"PeriodicalIF":9.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mirrored Metastatic Neuroendocrine Tumor in a Mother-Daughter Duo With Mutations in the MEN1 Gene. MEN1基因突变的母女二人镜像转移性神经内分泌肿瘤
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-05-01 Epub Date: 2025-02-28 DOI: 10.1097/RLU.0000000000005732
Piyush Aggarwal, Gurjeet Kaur, Sanjay Kumar Bhadada, Rajender Kumar, Somit Pandey, Ashwani Sood, Bhagwant Rai Mittal
{"title":"Mirrored Metastatic Neuroendocrine Tumor in a Mother-Daughter Duo With Mutations in the MEN1 Gene.","authors":"Piyush Aggarwal, Gurjeet Kaur, Sanjay Kumar Bhadada, Rajender Kumar, Somit Pandey, Ashwani Sood, Bhagwant Rai Mittal","doi":"10.1097/RLU.0000000000005732","DOIUrl":"10.1097/RLU.0000000000005732","url":null,"abstract":"<p><p>Multiple endocrine neoplasia (MEN) 1 syndrome may present with either of any or all neuroendocrine tumors (NETs), parathyroid and pituitary adenoma. There is a paucity of data on the intronic and exonic mutations in the MEN1 gene associated with the MEN1 syndrome. We present an interesting study of a mother-daughter duo of MEN1 who had a similar lesions distribution of metastatic NET and underwent genetic analysis to reveal a rare mutation in the MEN1 gene and both first-degree relatives presented with metastatic NET without any other syndromic manifestation of MEN1 syndrome. Both patients received peptide receptor radionuclide therapy.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e307-e309"},"PeriodicalIF":9.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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