发布求助
文献互助 智能选刊 最新文献

Clinical Nuclear Medicine最新文献

筛选
英文 中文
Feasibility and Safety of Peptide Receptor Radionuclide Therapy With 177Lu-DOTATATE for Neuroendocrine Tumor in a Patient With Sickle Cell Anemia.
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-03-03 DOI: 10.1097/RLU.0000000000005790
Ismaheel O Lawal, Olumide B Gbolahan, Charles Marcus, Aaron T Jones, Walid L Shaib, Saima Muzahir
{"title":"Feasibility and Safety of Peptide Receptor Radionuclide Therapy With 177Lu-DOTATATE for Neuroendocrine Tumor in a Patient With Sickle Cell Anemia.","authors":"Ismaheel O Lawal, Olumide B Gbolahan, Charles Marcus, Aaron T Jones, Walid L Shaib, Saima Muzahir","doi":"10.1097/RLU.0000000000005790","DOIUrl":"https://doi.org/10.1097/RLU.0000000000005790","url":null,"abstract":"<p><p>A 56-year-old woman with sickle cell anemia (SCA) and metastatic neuroendocrine tumor refractory to somatostatin analog received 4 cycles of peptide receptor radionuclide therapy (PRRT) with 177Lu-DOTATATE. The treatment schedule was delayed by multiple episodes of hospitalizations related to underlying SCA. PRRT was well-tolerated with stable renal, hematologic, and liver lab parameters. After PRRT, the disease remained stable for up to 13 months, and serum chromogranin levels declined by 45%. PRRT with 177Lu-DOTATATE can be safely administered for metastatic neuroendocrine tumors in patients with SCA with good anti-tumor effect. Disruption to the therapy schedule should be anticipated, given the potential for recurrent hospitalization for illnesses related to the underlying SCA.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
68Ga PSMA PET/CT and 18F FDG PET/CT Findings in Osteonecrosis of the Jaw Induced by Denosumab.
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-03-03 DOI: 10.1097/RLU.0000000000005751
Zehranur Tosunoğlu, Göksel Alçin, Elife Akgün, İlkay Gültürk, Esra Arslan
{"title":"68Ga PSMA PET/CT and 18F FDG PET/CT Findings in Osteonecrosis of the Jaw Induced by Denosumab.","authors":"Zehranur Tosunoğlu, Göksel Alçin, Elife Akgün, İlkay Gültürk, Esra Arslan","doi":"10.1097/RLU.0000000000005751","DOIUrl":"https://doi.org/10.1097/RLU.0000000000005751","url":null,"abstract":"<p><p>Breast cancer, prostate cancer, kidney cancer, multiple myeloma, osteoporosis, and the use of antiresorptive and antiangiogenic drugs are risk factors for osteonecrosis of the jaw (ONJ). Denosumab is a Receptor activator of nuclear factor kappa-Β ligand antagonist monoclonal antibody that inhibits the differentiation and function of osteoclasts over osteoblasts. It is an antiresorptive drug used to reduce the development of skeletal events in solid cancers. Denosumab-induced ONJ is a rare condition, occurring in 0% to 4.6% of cases. In this case, the findings of 68Ga prostate specific membrane antigen (PSMA) positron emission tomography (PET)/Computed Tomography (CT) and 18F Fluorodeoxyglucose (FDG) PET/CT are presented in a man with metastatic castration-resistant prostate cancer who developed ONJ due to denosumab use.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distinct Characteristics of Suspected Non-Alzheimer Pathophysiology in Relation to Cognitive Status and Cerebrovascular Burden.
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-03-03 DOI: 10.1097/RLU.0000000000005793
Min Young Chun, Yu Hyun Park, Hee Jin Kim, Duk L Na, Jun Pyo Kim, Sang Won Seo, Hyemin Jang
{"title":"Distinct Characteristics of Suspected Non-Alzheimer Pathophysiology in Relation to Cognitive Status and Cerebrovascular Burden.","authors":"Min Young Chun, Yu Hyun Park, Hee Jin Kim, Duk L Na, Jun Pyo Kim, Sang Won Seo, Hyemin Jang","doi":"10.1097/RLU.0000000000005793","DOIUrl":"https://doi.org/10.1097/RLU.0000000000005793","url":null,"abstract":"<p><strong>Purpose of the report: </strong>This study investigated the prevalence and clinical characteristics of suspected non-Alzheimer disease pathophysiology (SNAP) across varying cognitive statuses and cerebral small vessel disease (CSVD) burden.</p><p><strong>Patients and methods: </strong>We included 1992 participants with cognitive status categorized as cognitively unimpaired, mild cognitive impairment, or dementia. β-amyloid (Aβ, A) positivity was assessed by Aβ PET, and neurodegeneration (N) positivity was determined through hippocampal volume. Participants were further divided by the presence or absence of severe CSVD. The clinical and imaging characteristics of A-N+ (SNAP) group were compared with those of the A-N- and A+N+ groups.</p><p><strong>Results: </strong>SNAP participants were older and had more vascular risk factors compared with A-N- and A+N+ in the CSVD(-) cohort. SNAP and A+N+ showed similar cortical thinning. At the dementia stage, SNAP had a cognitive trajectory similar to A+N+ in the CSVD(-) cohort. However, SNAP exhibited less cognitive decline than A+N+ in the CSVD(+) cohort.</p><p><strong>Conclusions: </strong>SNAP is characterized by distinct clinical and imaging characteristics; however, it does not necessarily indicate a benign prognosis, particularly at the dementia stage. These findings highlight the need to assess SNAP in relation to the cognitive stage and CSVD presence to better understand its progression and guide interventions.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
18F-FDG PET/CT Findings Mimicking Gallbladder Metastasis From a Rectal Adenocarcinoma: Rare Synchronous Gallbladder and Rectal Cancer.
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-03-03 DOI: 10.1097/RLU.0000000000005812
Ahmet Ertuğrul Öztürk, Elife Akgün, Göksel Alçin, İlkay Gültürk, Saime Gül Barut, Esra Arslan
{"title":"18F-FDG PET/CT Findings Mimicking Gallbladder Metastasis From a Rectal Adenocarcinoma: Rare Synchronous Gallbladder and Rectal Cancer.","authors":"Ahmet Ertuğrul Öztürk, Elife Akgün, Göksel Alçin, İlkay Gültürk, Saime Gül Barut, Esra Arslan","doi":"10.1097/RLU.0000000000005812","DOIUrl":"https://doi.org/10.1097/RLU.0000000000005812","url":null,"abstract":"<p><p>Metastasis from rectal adenocarcinoma (RAC) to the gallbladder (GB) is rare. Differentiating GB metastasis from primary gallbladder cancer (GBC) is important for treatment planning. A patient diagnosed RAC with 18F-FDG PET/CT found suspicious findings of GB metastasis. However, after surgery was found to be primary GBC. The incidence of multiple primary tumors (MPTs) varies 2.4%-8%. In this case report, we would like to present 18F-FDG PET/CT findings of rare synchronous coexistence of GBC and RAC, and also that, although rare, metastasis from the RAC to the GB should definitely be kept in mind.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two Distinct Hyperactive Thyrothymic Remnants in a Patient With Graves' Disease.
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-03-03 DOI: 10.1097/RLU.0000000000005715
Malik E Juweid, Marwah Abdulrahman, Omar Albtoush, Soud F Al-Qasem
{"title":"Two Distinct Hyperactive Thyrothymic Remnants in a Patient With Graves' Disease.","authors":"Malik E Juweid, Marwah Abdulrahman, Omar Albtoush, Soud F Al-Qasem","doi":"10.1097/RLU.0000000000005715","DOIUrl":"https://doi.org/10.1097/RLU.0000000000005715","url":null,"abstract":"<p><p>A 40-year-old woman with Graves' disease underwent a technetium-99m pertechnetate thyroid scan showing two distinct foci of increased uptake, one just inferior to the right thyroid lobe and another further down in the right supraclavicular region. The foci were subsequently identified by contrast-enhanced computed tomography and interpreted as grade 4 thyrothymic remnants, both separate from the genuine thyroid. Detection of such variants by thyroid scintigraphy and anatomic imaging in such patients is important to minimize the risk of persistent/recurrent hyperthyroidism after surgery.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary Metastases From Early-stage Granulosa Cell Tumor 15 Years Later on 18F-NOTA-FAPI-04 and 18F-FDG PET/CT.
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-03-03 DOI: 10.1097/RLU.0000000000005801
Yan Cui, Xin Zhou, Xiangping Guan, Nan Li
{"title":"Pulmonary Metastases From Early-stage Granulosa Cell Tumor 15 Years Later on 18F-NOTA-FAPI-04 and 18F-FDG PET/CT.","authors":"Yan Cui, Xin Zhou, Xiangping Guan, Nan Li","doi":"10.1097/RLU.0000000000005801","DOIUrl":"https://doi.org/10.1097/RLU.0000000000005801","url":null,"abstract":"<p><p>This article reports a case of rare pulmonary metastases arising from an ovarian granulosa cell tumor using 18F-NOTA-FAPI-04 PET/CT. We discussed a patient who was diagnosed with ovarian granulosa cell tumor (stage IA) after surgery 15 years ago and developed pulmonary metastases. The metastatic lesions with solid and (or) cystic components displayed variable (none to mild) fluorodeoxyglucose (FDG) avidity and significantly higher uptake of FAPI. This case highlighted the utility of 18F-NOTA-FAPI-04 PET/CT, suggesting that it may serve as a promising novel tool for the diagnosis and staging of ovarian granulosa cell tumors.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
99mTc-PSMA Uptake in Neurofibroma.
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-03-03 DOI: 10.1097/RLU.0000000000005797
Mohammad Hadi Samadi, Pegah Sahafi, Haniye Elahifard, Sima Davoodi, Emran Askari
{"title":"99mTc-PSMA Uptake in Neurofibroma.","authors":"Mohammad Hadi Samadi, Pegah Sahafi, Haniye Elahifard, Sima Davoodi, Emran Askari","doi":"10.1097/RLU.0000000000005797","DOIUrl":"https://doi.org/10.1097/RLU.0000000000005797","url":null,"abstract":"<p><p>We present a 74-year-old man with a history of very high-risk prostate cancer (Gleason score: 5+4 in 11 of 14 cores) who was referred for initial staging with 99mTc-HYNIC-PSMA. The scan was reported as miT2m N2(REI, ROB) M1b(uni) M1c(skin?), PRIMARY score: 4, PSMA expression score: 1-3. We incidentally discovered increased uptake in the left skull region on whole-body images. Subsequent SPECT/CT imaging localized this uptake to a subcutaneous nodule in the scalp, which pathologic analysis confirmed to be a neurofibroma. Several lesions of neurological origin may exhibit significant PSMA avidity, which is reviewed here.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oromandibular Dyskinesia: Diagnostic Insights From 18F-FDG PET/CT Imaging.
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-03-03 DOI: 10.1097/RLU.0000000000005725
Anjali Jain, Sharjeel Usmani, Khulood Al Riyami, Asiya Al Busaidi, Sofiullah Abubakar, Subhash Kheruka, Rashid Al Sukaiti
{"title":"Oromandibular Dyskinesia: Diagnostic Insights From 18F-FDG PET/CT Imaging.","authors":"Anjali Jain, Sharjeel Usmani, Khulood Al Riyami, Asiya Al Busaidi, Sofiullah Abubakar, Subhash Kheruka, Rashid Al Sukaiti","doi":"10.1097/RLU.0000000000005725","DOIUrl":"https://doi.org/10.1097/RLU.0000000000005725","url":null,"abstract":"<p><p>Oromandibular dyskinesia is an abnormal, repetitive, involuntary movement of the jaw, tongue, and lips. We report an interesting image of a 72-year-old woman, who underwent 18F- FDG PET/CT for restaging of treated colon cancer. PET/CT scan shows diffuse uptake in orbicularis oris, muscles of the lips, muscles around the mandible and in the oral cavity, and anterior tongue muscles with no abnormality seen on corresponding CT images. A thorough search into patient history revealed the diagnosis of oromandibular dyskinesia.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positive 68 Ga-FAPI-04 PET/MRI and Negative 18 F-FDG PET/CT Imaging in Incidental Appendiceal Goblet Cell Adenocarcinoma. 阑尾鹅口疮细胞腺癌的 68Ga-FAPI-04 PET/MRI 阳性和 18F-FDG PET/CT 阴性成像。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-03-01 Epub Date: 2024-10-02 DOI: 10.1097/RLU.0000000000005490
Yu Sun, Haiyan Wang, Xing Chen, Weilun Wang, Jun Zhao
{"title":"Positive 68 Ga-FAPI-04 PET/MRI and Negative 18 F-FDG PET/CT Imaging in Incidental Appendiceal Goblet Cell Adenocarcinoma.","authors":"Yu Sun, Haiyan Wang, Xing Chen, Weilun Wang, Jun Zhao","doi":"10.1097/RLU.0000000000005490","DOIUrl":"10.1097/RLU.0000000000005490","url":null,"abstract":"<p><strong>Abstract: </strong>A 70-year-old woman presented with left ovarian mass and thickened peritoneum. 18 F-FDG PET/CT showed no significant FDG-avid in the whole body. 68 Ga-FAPI-04 demonstrated abnormally high FAPI uptake in the ileocecal region, left ovarian lesion, and thickened peritoneum. The postoperative pathology confirmed the appendiceal goblet cell adenocarcinoma. This case highlights the superior and innovative diagnostic role of 68 Ga-FAPI-04 in appendiceal goblet cell adenocarcinoma and its metastases.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"250-251"},"PeriodicalIF":9.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142361267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FDG Uptake in Brown Adipose Tissue Activated by a Long-Acting β2-Adrenergic Receptor Agonist Inhaler Prescribed for Bronchial Asthma. 治疗支气管哮喘的长效β2-肾上腺素能受体激动剂吸入剂激活了棕色脂肪组织的 FDG 摄取。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-03-01 Epub Date: 2024-10-10 DOI: 10.1097/RLU.0000000000005529
Akira Nitta, Tomoya Kotani, Chio Okuyama
{"title":"FDG Uptake in Brown Adipose Tissue Activated by a Long-Acting β2-Adrenergic Receptor Agonist Inhaler Prescribed for Bronchial Asthma.","authors":"Akira Nitta, Tomoya Kotani, Chio Okuyama","doi":"10.1097/RLU.0000000000005529","DOIUrl":"10.1097/RLU.0000000000005529","url":null,"abstract":"<p><strong>Abstract: </strong>We herein report a case of an elderly woman in whom brown adipose tissue (BAT) was visible on 18 F-FDG PET imaging performed in the summer. In this patient, none of the well-known factors that induce BAT activation in adults, including cold exposure, catecholamine-producing tumors, or β3-adrenergic receptor agonists administration, were present. Daily inhalation of a long-acting β2-adrenergic agonist for treatment of her bronchial asthma was considered the cause of her BAT visualization. This case suggests the need to consider β2-adrenergic receptor agonists as a cause of BAT visualization.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"252-254"},"PeriodicalIF":9.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142388649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信