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Diagnostic Challenges in Invasive Mole With 18 F-FDG PET/CT. 利用 18F-FDG PET/CT 诊断侵袭性痣的挑战。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2024-12-01 Epub Date: 2024-07-22 DOI: 10.1097/RLU.0000000000005378
Akihiko Minami, Ryusuke Nakamoto, Takuto Shimamura, Yurika Kitano, Yuji Nakamoto
{"title":"Diagnostic Challenges in Invasive Mole With 18 F-FDG PET/CT.","authors":"Akihiko Minami, Ryusuke Nakamoto, Takuto Shimamura, Yurika Kitano, Yuji Nakamoto","doi":"10.1097/RLU.0000000000005378","DOIUrl":"10.1097/RLU.0000000000005378","url":null,"abstract":"<p><strong>Abstract: </strong>A 34-year-old woman underwent 18 F-FDG PET/CT scan following a diagnosis of an invasive mole. Although CT indicated multiple lung metastases, FDG uptakes were not evident. In contrast, FDG uptakes were observed in the pelvic lesion including the left ovary, suggestive of ovarian metastasis. MRI disclosed a ring-shaped enhancement typical of a corpus luteum. This corpus luteum was supposed to be maintained by the elevated human chorionic gonadotropin excreted from the invasive mole. This case underlines the importance of careful interpretation of 18 F-FDG PET/CT in the evaluation of invasive moles, highlighting potential false positive in corpus luteum.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"1148-1149"},"PeriodicalIF":9.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141751283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FDG PET/CT in Staging of α-Fetoprotein-Producing Hepatoid Adenocarcinoma of the Pancreas. FDG PET/CT 在α-胎儿蛋白肝胰腺腺癌分期中的应用
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2024-12-01 Epub Date: 2024-08-01 DOI: 10.1097/RLU.0000000000005399
Xia Ji, Aisheng Dong, Yang Wang
{"title":"FDG PET/CT in Staging of α-Fetoprotein-Producing Hepatoid Adenocarcinoma of the Pancreas.","authors":"Xia Ji, Aisheng Dong, Yang Wang","doi":"10.1097/RLU.0000000000005399","DOIUrl":"10.1097/RLU.0000000000005399","url":null,"abstract":"<p><strong>Abstract: </strong>Hepatoid adenocarcinoma of the pancreas is a rare aggressive tumor with poor prognosis. We describe contrast-enhanced CT and FDG PET/CT findings in a case of pancreatic hepatoid adenocarcinoma with significantly elevated α-fetoprotein level presenting as acute pancreatitis. The primary pancreatic tumor diffusely involved the pancreas and showed heterogeneous enhancement mimicking acute necrotizing pancreatitis on contrast-enhanced CT. FDG PET/CT showed intense FDG uptake (SUV max , 24.5) of the left supraclavicular and retroperitoneal lymph node metastases, suggesting FDG PET/CT may be useful for staging of this aggressive tumor.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"1115-1117"},"PeriodicalIF":9.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodality Evaluation of Persistent Hyperparathyroidism in a Rare Case of Ectopic Submandibular Parathyroid Adenoma. 对一例异位颌下腺甲状旁腺腺瘤罕见病例的持续性甲状旁腺功能亢进进行多模式评估
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2024-12-01 Epub Date: 2024-09-25 DOI: 10.1097/RLU.0000000000005495
Yeshwanth Edamadaka, Gaurav Malhotra, Aaditya Daga, Saba S Memon, Anurag R Lila, Tushar Bandgar
{"title":"Multimodality Evaluation of Persistent Hyperparathyroidism in a Rare Case of Ectopic Submandibular Parathyroid Adenoma.","authors":"Yeshwanth Edamadaka, Gaurav Malhotra, Aaditya Daga, Saba S Memon, Anurag R Lila, Tushar Bandgar","doi":"10.1097/RLU.0000000000005495","DOIUrl":"10.1097/RLU.0000000000005495","url":null,"abstract":"<p><strong>Abstract: </strong>A 53-year-old woman of primary hyperparathyroidism with both ultrasound neck examination and planar 99m Tc-MIBI scan being negative revealed a tracer-avid focus in the left submandibular region in early (15 minutes postinjection) 99m Tc-MIBI SPECT/CT views, raising a suspicion of rare ectopic parathyroid adenoma. This finding was correlated on 4D-CT and confirmed on histopathology following surgical excision. Submandibular region is an unusual location for ectopic parathyroid adenoma. Nevertheless, high degree of suspicion with utilization of multimodality imaging including 99m Tc MIBI-SPECT/CT and 4D-CT improves preoperative detection of parathyroid adenoma at rare ectopic sites as seen in this case of persistent hyperparathyroidism.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e670-e673"},"PeriodicalIF":9.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142343073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metastatic Lung Adenocarcinoma Presenting Within Struma Ovarii: A Rare Case of Tumor-to-Tumor Metastasis. 转移性肺腺癌出现在鳞状上皮内：肿瘤间转移的罕见病例
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2024-12-01 Epub Date: 2024-10-24 DOI: 10.1097/RLU.0000000000005527
Lee So Maeng, Ah Young Shin, Eun Kyoung Choi, Jin Kyoung Oh, Yong-An Chung
{"title":"Metastatic Lung Adenocarcinoma Presenting Within Struma Ovarii: A Rare Case of Tumor-to-Tumor Metastasis.","authors":"Lee So Maeng, Ah Young Shin, Eun Kyoung Choi, Jin Kyoung Oh, Yong-An Chung","doi":"10.1097/RLU.0000000000005527","DOIUrl":"10.1097/RLU.0000000000005527","url":null,"abstract":"<p><strong>Abstract: </strong>Tumor-to-tumor metastasis is extremely rare. We herein describe a 67-year-old woman who underwent FDG PET/CT for initial staging of lung cancer. This imaging examination revealed a pelvic mass with peripheral FDG uptake, suggesting a metastatic tumor from lung cancer or a secondary malignancy. Examination of a surgical specimen confirmed metastatic lung adenocarcinoma within a struma ovarii, suggesting tumor-to-tumor metastasis.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e699-e701"},"PeriodicalIF":9.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Elevated 68 Ga-FAPI Activity in Benign Carotid Body Tumors. 良性颈动脉体瘤的 68Ga-FAPI 活性升高
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2024-12-01 Epub Date: 2024-07-16 DOI: 10.1097/RLU.0000000000005364
Yang Xie, Wenxin Tang, Xi Chen, Xue Bai, Yue Chen
{"title":"Elevated 68 Ga-FAPI Activity in Benign Carotid Body Tumors.","authors":"Yang Xie, Wenxin Tang, Xi Chen, Xue Bai, Yue Chen","doi":"10.1097/RLU.0000000000005364","DOIUrl":"10.1097/RLU.0000000000005364","url":null,"abstract":"<p><strong>Abstract: </strong>We present 68 Ga-FAPI PET/CT findings of benign carotid body tumor in a 33-year-old woman. Benign carotid body tumor demonstrated intense tracer uptakes on 68 Ga-FAPI PET/CT. Our case suggests that benign carotid body tumors should be considered in the differential diagnosis of neck mass with elevated 68 Ga-FAPI activity.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"1122-1123"},"PeriodicalIF":9.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141619577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Osteoid Osteoma of the Medial Cuneiform Bone at Tibialis Anterior Insertion Confirmed by Bone Scan SPECT/CT. 通过骨扫描 SPECT/CT 确诊的胫骨前端内侧楔骨骨样骨瘤罕见病例
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2024-12-01 Epub Date: 2024-10-10 DOI: 10.1097/RLU.0000000000005497
Pegah Sahafi, Ramin Sadeghi, Alireza Mousavian
{"title":"A Rare Case of Osteoid Osteoma of the Medial Cuneiform Bone at Tibialis Anterior Insertion Confirmed by Bone Scan SPECT/CT.","authors":"Pegah Sahafi, Ramin Sadeghi, Alireza Mousavian","doi":"10.1097/RLU.0000000000005497","DOIUrl":"10.1097/RLU.0000000000005497","url":null,"abstract":"<p><strong>Abstract: </strong>A 34-year-old man presented with progressive foot pain that was initially on the medial soft tissue but eventually localized to the medial side of midfoot. Despite undergoing various imaging tests and conservative treatments over 2 years, the patient remained undiagnosed. After 6 months, soft tissue and bone involvement were observed on the medial cuneiform. A needle biopsy was inconclusive. Since bone tumor is rare in the medial cuneiform, the patient was referred to our department for 99m Tc-MDP bone scan. The imaging and clinical findings suggested osteoid osteoma as the likely diagnosis, which was confirmed as intraarticular nidus under tibialis anterior attachment, after surgical resection and pathological examination.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e680-e681"},"PeriodicalIF":9.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
177 Lu-PSMA-617 Radioligand Therapy in Patient With Prostate Cancer Sciatic Nerve Metastasis. 前列腺癌坐骨神经转移患者的 177Lu-PSMA-617 放射配体疗法
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2024-12-01 Epub Date: 2024-10-14 DOI: 10.1097/RLU.0000000000005503
David Tonnelet, Agathe Edet-Sanson, Laetitia Augusto, Marine Cabourg, Sébastien Thureau
{"title":"177 Lu-PSMA-617 Radioligand Therapy in Patient With Prostate Cancer Sciatic Nerve Metastasis.","authors":"David Tonnelet, Agathe Edet-Sanson, Laetitia Augusto, Marine Cabourg, Sébastien Thureau","doi":"10.1097/RLU.0000000000005503","DOIUrl":"10.1097/RLU.0000000000005503","url":null,"abstract":"<p><strong>Abstract: </strong>Patients with metastatic castration-resistant prostate cancer usually have lymph nodes and bone metastasis. We present a rare case of a 51-year-old patient with metastatic castration-resistant prostate cancer who complained of left truncated sciatica and diffuse bone pain and who was referred for 177 Lu-prostate-specific membrane antigen (PSMA) screening. Pretreatment 68 Ga-PSMA showed left sciatic nerve and multiple bone uptake. Patient underwent stereotactic radiotherapy on the sciatic nerve metastasis (30 Gy in 6 fractions of 5 Gy) before 7.4 GBq of 177 Lu-PSMA infusions. Left truncated sciatica disappeared after stereotactic radiotherapy. No additional toxicity was added to the sciatic nerve from 177 Lu-PSMA after stereotactic radiotherapy.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e668-e669"},"PeriodicalIF":9.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142521229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heterogeneous Uptake of Al 18 F-NOTA-FAPI and 18 F-FDG in Apical Aneurysm in Apical Hypertrophic Cardiomyopathy. 心尖肥厚型心肌病心尖动脉瘤对 Al 18 F-NOTA-FAPI 和 18 F-FDG 的异质性摄取
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2024-12-01 Epub Date: 2024-10-10 DOI: 10.1097/RLU.0000000000005530
Yang Xu, Yue-Hong Guo, Min-Fu Yang
{"title":"Heterogeneous Uptake of Al 18 F-NOTA-FAPI and 18 F-FDG in Apical Aneurysm in Apical Hypertrophic Cardiomyopathy.","authors":"Yang Xu, Yue-Hong Guo, Min-Fu Yang","doi":"10.1097/RLU.0000000000005530","DOIUrl":"10.1097/RLU.0000000000005530","url":null,"abstract":"<p><strong>Abstract: </strong>Apical aneurysm in apical hypertrophic cardiomyopathy (HCM) is a very rare condition in clinical practice. Some studies have reported abnormal uptake of 18 F-FDG and 18 F-FAPI in HCM, respectively. We presented a case of FAPI and FDG imaging in a patient with apical aneurysm in apical HCM, and further analyzed the discrepancy of spatial distribution pattern of these 2 radiotracers.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e715-e717"},"PeriodicalIF":9.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142388651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-TACE FDG Accumulation in HCC Surrounding the Liver Parenchyma: Distinguishing Between Inflammatory Pseudotumors and HCC. 肝实质周围 HCC 的 TACE 后 FDG 累积：区分炎性假瘤和 HCC。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2024-12-01 Epub Date: 2024-10-10 DOI: 10.1097/RLU.0000000000005486
Mirei Abe, Yoshitaka Toyama, Akitoshi Sano, Kentaro Takanami, Kei Takase
{"title":"Post-TACE FDG Accumulation in HCC Surrounding the Liver Parenchyma: Distinguishing Between Inflammatory Pseudotumors and HCC.","authors":"Mirei Abe, Yoshitaka Toyama, Akitoshi Sano, Kentaro Takanami, Kei Takase","doi":"10.1097/RLU.0000000000005486","DOIUrl":"10.1097/RLU.0000000000005486","url":null,"abstract":"<p><strong>Abstract: </strong>An 80-year-old patient with hepatocellular carcinoma (HCC) underwent an 18 F-FDG PET/CT scan owing to suspected lumbar metastasis identified via a CT scan performed during transarterial chemoembolization (TACE) 2 weeks earlier. The PET scan revealed segmental high uptake in the HCC and surrounding liver parenchyma, where lipiodol deposited during TACE had mostly washed out. The segmental uptake was attributed to TACE-induced inflammatory changes in the liver parenchyma around the HCC, confirmed by reduced uptake in a follow-up 18 F-FDG PET/CT scan 4 months later. This highlights the need to differentiate between inflammation and viable HCC in post-TACE 18 F-FDG PET/CT evaluations.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"1109-1111"},"PeriodicalIF":9.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142388655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physiological Gallbladder Accumulation on 68 Ga-FAPI-46 PET/CT. 68Ga-FAPI-46 PET/CT 上的胆囊生理性积聚。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2024-12-01 Epub Date: 2024-10-10 DOI: 10.1097/RLU.0000000000005480
Ömer Faruk Şahin, Göksel Alçın, Nurhan Ergül, Tevfik Fikret Çermik, Esra Arslan
{"title":"Physiological Gallbladder Accumulation on 68 Ga-FAPI-46 PET/CT.","authors":"Ömer Faruk Şahin, Göksel Alçın, Nurhan Ergül, Tevfik Fikret Çermik, Esra Arslan","doi":"10.1097/RLU.0000000000005480","DOIUrl":"10.1097/RLU.0000000000005480","url":null,"abstract":"<p><strong>Abstract: </strong>Radiolabeled fibroblast activation protein inhibitors (FAPIs) are a novel approach in cancer detection and treatment. Targeting fibroblast activation protein, extensively produced by cancer-associated fibroblasts, FAPI plays a key role in tumor development. Its advanced imaging capabilities offer clearer results in solid tumors compared with traditional methods, drawing significant interest in oncology. Additionally, FAPI's activity in conditions requiring tissue remodeling, such as atherosclerosis and arthritis, highlights its broader potential. This interesting image shows the physiological accumulation of 68 Ga-FAPI in the gallbladder, emphasizing the importance of accurate interpretation to prevent misdiagnoses and ensure effective patient management.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e685-e686"},"PeriodicalIF":9.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142521236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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