18F-FDG PET/CT在直肠癌中对模拟腹膜癌的聚苯乙烯磺酸钠晶体的巨噬反应

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-10-01 Epub Date: 2025-04-18 DOI:10.1097/RLU.0000000000005917

V Habouzit, F Casteillo, H Boutallaka, O Perotto, R Grange

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引用次数: 0

摘要

一位68岁的男性在接受上直肠癌高度复杂的手术1年后出现直肠出血。内镜活检证实直肠残端局部复发。18F-FDG PET/CT显示腹膜结节强烈摄取，提示腹膜癌。然而，腹腔镜检查和病理分析发现，与聚苯乙烯磺酸钠（Kayexalate）一致的嗜碱性晶体是异物肉芽肿反应的原因，没有肿瘤复发的证据。本病例强调了在有严重腹部并发症史的患者中考虑腹膜PET/CT假阳性的罕见原因的重要性，以确保准确的诊断和适当的处理。

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Macrophagic Reaction to Sodium Polystyrene Sulfonate Crystals Mimicking Peritoneal Carcinomatosis on 18 F-FDG PET/CT in Rectal Cancer.

A 68-year-old man presented with rectal bleeding 1 year after a highly complicated surgical course for upper rectal cancer. Endoscopic biopsy confirmed a local recurrence at the rectal stump. 18 F-FDG PET/CT showed intense uptake in peritoneal nodules, suggesting peritoneal carcinomatosis. However, exploratory laparoscopy and pathologic analysis identified basophilic crystals consistent with sodium polystyrene sulfonate (Kayexalate) as the cause of a foreign-body granulomatous reaction, with no evidence of tumor recurrence. This case underscores the importance of considering rare causes of peritoneal false-positive PET/CT findings in patients with a history of severe abdominal complications, ensuring accurate diagnosis and appropriate management.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.