Clinical science and molecular medicine. Supplement最新文献_第8页

The effects of calcium and calcium-ionophores (X 537 A and A 23187) on renin release in the isolated perfused rat kidney. 钙和钙离子载体(X 537a和A 23187)对离体灌注大鼠肾脏肾素释放的影响。

Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01

U Schwertschlag, E Hackenthal, R Hackenthal, G H Rohs

引用次数: 0

Long-term treatment of hypertension in man by an orally active angiotensin-converting enzyme inhibitor. 口服活性血管紧张素转换酶抑制剂对高血压的长期治疗。

Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055293s

H R Brunner, H Gavras, G A Turini, B Waeber, P Cappuis, D N McKinstry

引用次数: 21

Brain catecholamines and catecholamine-synthesizing enzymes in renovascular hypertension in the rat. 肾血管性高血压大鼠脑内儿茶酚胺及儿茶酚胺合成酶的研究。

Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055101s

M A Petty, J L Reid

引用次数: 4

Labetalol in hypertensive patients with angina pectoris: beneficial effect of combined alpha- and beta-adrenoreceptor blockade. 拉贝他洛尔对合并心绞痛的高血压患者:联合肾上腺素受体阻断的有益效果。

Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055283s

W F Lubbe, D A White

{"title":"Labetalol in hypertensive patients with angina pectoris: beneficial effect of combined alpha- and beta-adrenoreceptor blockade.","authors":"W F Lubbe, D A White","doi":"10.1042/cs055283s","DOIUrl":"https://doi.org/10.1042/cs055283s","url":null,"abstract":"1. Eight hypertensive patients with angina pectoris had placebo added to their existing medications for 8 weeks, then incremental doses of active labetalol with simultaneous stepwise reduction in other medicines until blood pressure was satisfactorily controlled; after that only labetalol and thiazide (8 weeks) and finally labetalol-placebo together with previous beta-adrenoreceptor antagonists and thiazide for 4 weeks were administered. 2. During the labetalol plus thiazide period resting blood pressures and measurements obtained during isotonic exercise, isometric exercise and the cold pressor test were significantly lower than during the initial placebo addition period. Angina scores were significantly reduced during this period. 3. During the final treatment with placebo, beta-adrenoreceptor antagonist and thiazide, blood pressures remained reduced, but angina was significantly worse. 4. Labetalol which antagonizes both alpha- and beta-adrenoreceptors produced better relief of angina pectoris than beta-adrenoreceptor antagonists during improvement in blood pressure in hypertensive patients.","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"283s-286s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055283s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11254598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Relation between prognosis and the blood pressure before and during treatment of hypertensive patients. 高血压患者治疗前后血压与预后的关系。

Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055333s

D G Beevers, J Johnston, B L Devine, F G Dunn, H Larkin, D M Titterington

{"title":"Relation between prognosis and the blood pressure before and during treatment of hypertensive patients.","authors":"D G Beevers, J Johnston, B L Devine, F G Dunn, H Larkin, D M Titterington","doi":"10.1042/cs055333s","DOIUrl":"https://doi.org/10.1042/cs055333s","url":null,"abstract":"1. A study was conducted amongst 1247 treated hypertensive patients to determine the predictive power of untreated baseline and achieved treated blood pressures in the development of the complications of hypertension. In addition the relative importance of systolic and diastolic pressures was calculated. 2. Statistical analysis was done by calculating univariate differences in blood pressure between cases with and without complications. The higher the univariate distance, the greater the predictive power. 3. Blood pressures achieved during treatment were more important than baseline pressures for predicting stroke in both men and women, confirming the benefits of antihypertensive therapy in preventing strokes. 4. There was some evidence of prevention of myocardial infarction in men and of angina in women as a result of therapy. 5. There was no evidence to suggest that any one group of drugs, including beta-adrenoreceptor-blocking drugs and thiazides, conferred any extra benefit in preventing coronary heart disease. 6. The systolic blood pressures achieved during treatment predicted stroke better than diastolic pressure, but no consistent trends were found for coronary heart disease.","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"333s-336s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055333s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11255435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24

Altered activity of the sodium-potassium pump in arteries of rats with steroid hypertension. 类固醇性高血压大鼠动脉钠钾泵活性的改变。

Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055041s

M B Pamnani, D L Clough, F J Haddy

引用次数: 72

The hypertension register of the North Karelia project. 北卡累利阿项目的高血压登记册。

Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055355s

A Nissinen, J Tuomilehto, P Puska

{"title":"The hypertension register of the North Karelia project.","authors":"A Nissinen, J Tuomilehto, P Puska","doi":"10.1042/cs055355s","DOIUrl":"https://doi.org/10.1042/cs055355s","url":null,"abstract":"1. One major subprogramme of the North Karelia Project was the hypertension programme which aimed at lowering of the high blood pressure among the whole population, and expecially among middle-aged men. The hypertension programme consisted of intervention integrated with the existing health care structure of the county of North Karelia. 2. The hypertension register, which was the major tool of the programme, aimed to maintain patients in treatment and to get information about the development of the programme. Registration of hypertensive subjects was continuous between 1972 and 1977 and registered patients had annual follow-up examinations. 3. After 5 years of the programme, there were approximately 17 000 registered patients which is 9.7% of the total population. 4. Proportion of drop-outs at the annual follow-up examinations was less than 10%. 83% of the registered hypertensive subjects were under drug treatment after 3 years intervention. The percentage of normotensive subjects increased significantly year by year. 5. Preliminary results from the stroke register of the North Karelia Project indicate that the incidence of stroke decreased as hypertension control was improved.","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"355s-358s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055355s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11495792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Pressure-independent hypertrophy of veins and pulmonary arteries of spontaneously hypertensive rats. Characterization of function, structural and histochemical changes. 自发性高血压大鼠静脉和肺动脉的压力不依赖型肥大。功能、结构和组织化学变化的表征。

Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055031s

S Greenberg, E C Palmer, W M Wilborn

引用次数: 30

The relationship between blood pressure and aortic collagen metabolism in renal hypertensive rats. 肾性高血压大鼠血压与主动脉胶原代谢的关系。

Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055027s

J M Foidart, G L Rorive, B V Nusgens, C M Lapiere

引用次数: 0

Evidence for an unidentified, adrenocorticotrophic hormone-dependent mineralocorticoid maintaining hypertension in young women with hypoaldosteronism. 证据不明，肾上腺皮质促激素依赖的矿物皮质激素维持高血压的年轻女性低醛固酮增多症。

Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055271s

W H Hoefnagels, J I Drayer, J A Hofman, A G Smals, T J Benraad, P W Kloppenborg

引用次数: 0