发布求助
文献互助 智能选刊 最新文献

Clinical science and molecular medicine. Supplement最新文献

筛选
英文 中文
The retention of lung secretions during the night in normal subjects. 正常受试者夜间肺分泌物潴留。
Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs0550523
J R Bateman, D Pavia, S W Clarke
{"title":"The retention of lung secretions during the night in normal subjects.","authors":"J R Bateman,&nbsp;D Pavia,&nbsp;S W Clarke","doi":"10.1042/cs0550523","DOIUrl":"https://doi.org/10.1042/cs0550523","url":null,"abstract":"<p><p>1. Mucociliary clearance has been measured over a 6 h period by using the radioaerosol technique in seven normal male subjects lying supine, both during the day when awake, and during the night when asleep. 2. The percentage of radioaerosol cleared during the night, when asleep, was significantly less than during the day when awake (P less than 0.02). 3. A comparison of radioaerosol clearance before and after the time of onset of sleep demonstrates that reduced clearance occurred during sleep, indicating that this is probably a sleep-related phenomenon and not merely a result of diurnal variation. 4. This finding has important implications for patients with chronic bronchitis or asthma, in whom early morning cough or wheeze may be a predominant feature.</p>","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"55 6","pages":"523-7"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs0550523","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11496796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 65
Albumin/globulin rations, colloid osmotic pressures and Lowry protein microanalysis in rat plasma. 大鼠血浆白蛋白/球蛋白定量、胶体渗透压和Lowry蛋白微量分析。
Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs0550529
D Weller, S Azar, M A Johnson, M Azar
{"title":"Albumin/globulin rations, colloid osmotic pressures and Lowry protein microanalysis in rat plasma.","authors":"D Weller,&nbsp;S Azar,&nbsp;M A Johnson,&nbsp;M Azar","doi":"10.1042/cs0550529","DOIUrl":"https://doi.org/10.1042/cs0550529","url":null,"abstract":"","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"55 6","pages":"529-32"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs0550529","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11496797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Different responses of active and inactive plasma renin to various stimuli. 血浆肾素活性与非活性对不同刺激的不同反应。
Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055155s
K W Rumpf, B Schächterle, S Schmidt, K Becker, F Scheler
{"title":"Different responses of active and inactive plasma renin to various stimuli.","authors":"K W Rumpf,&nbsp;B Schächterle,&nbsp;S Schmidt,&nbsp;K Becker,&nbsp;F Scheler","doi":"10.1042/cs055155s","DOIUrl":"https://doi.org/10.1042/cs055155s","url":null,"abstract":"<p><p>1. The response of active and inactive plasma renin to orthostasis and frusemide and to inhibition of prostaglandin synthesis by indomethacin was tested in normal human volunteers. 2. Active renin increased by orthostasis and frusemide and decreased by indomethacin. The latter also blunted the increase of active renin after stimuli. 3. Inactive renin was slightly increased by orthostasis, but was not significantly influenced by acute administration of frusemide or inhibition of prostaglandin synthesis by indomethacin. 4. The results show differences in the response of active and inactive renin to stimuli and suppression. Opposite changes of active and inactive renin were not observed in the experimental conditions studied.</p>","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"155s-157s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055155s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11495151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 31
Differences in reflex control of arterial pressure and renin release during head-up tilting in the cat. 猫直立倾斜时动脉压和肾素释放的反射控制差异。
Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055179s
A Stella, R A Dampney, R Golin, A Zanchetti
{"title":"Differences in reflex control of arterial pressure and renin release during head-up tilting in the cat.","authors":"A Stella,&nbsp;R A Dampney,&nbsp;R Golin,&nbsp;A Zanchetti","doi":"10.1042/cs055179s","DOIUrl":"https://doi.org/10.1042/cs055179s","url":null,"abstract":"<p><p>1. Anaesthetized cats were subjected to two 10 min trials of head-up tilting spaced 30 min. Arterial pressure, heart rate, blood flow to an innervated kidney and to the contralateral denervated one, and renin release from both kidneys were measured. 2. The same haemodynamic changes and comparable increases in renin release from innervated kidneys occurred during both episodes of tilting when cats were subjected to sham cervical vagotomy between the two tilting trials. 3. Bilateral cervical vagotomy, performed after the first episode of head-up tilting, did not affect the haemodynamic response to the change in posture, but significantly and markedly reduced the increase in renin release from the innervated kidney. 4. After sino-aortic denervation a marked and sustained arterial hypotension occurred during tilting, and the postural increase in renin release from the innervated kidney was even greater. 5. In no condition, even during the marked fall in blood pressure in sino-aortic denervated cats, did head-up tilting increase renin release from the denervated kidney. 6. It is concluded that maintenance of arterial pressure during tilting is mainly due to sino-aortic reflexes, whereas vagal reflexes are mostly responsible for the postural increase in renin release.</p>","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"179s-181s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055179s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11495155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Circulating catecholamines and systolic time intervals in labile and sustained hypertension. 不稳定和持续性高血压的循环儿茶酚胺和收缩时间间隔。
Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055065s
D Cousineau, J De Champlain, L Lapointe
{"title":"Circulating catecholamines and systolic time intervals in labile and sustained hypertension.","authors":"D Cousineau,&nbsp;J De Champlain,&nbsp;L Lapointe","doi":"10.1042/cs055065s","DOIUrl":"https://doi.org/10.1042/cs055065s","url":null,"abstract":"<p><p>1. Average supine circulating total catecholamine concentrations were found to be higher than the normal range in about 50% of patients with labile hypertension and in about 30% of patients with sustained essential hypertension. 2. These higher resting concentrations were mainly due to an increase in adrenaline in labile hypertension and to an increase in noradrenaline in sustained hypertension. 3. Patients with elevated catecholamine concentrations were also characterized by a higher heart rate, by an increased myocardial contractility and by greater hypotensive response after treatment with beta-adrenoreceptor blocking agents. 4. These studies suggest the existence of sub-groups of hypertensive patients with increased sympathetic tone.</p>","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"65s-68s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055065s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11495624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 39
The effect of mental arithmetic on blood pressure variability and baroreflex sensitivity in man. 心算对人血压变异性和气压反射敏感性的影响。
Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055381s
P Sleight, P Fox, R Lopez, D E Brooks
{"title":"The effect of mental arithmetic on blood pressure variability and baroreflex sensitivity in man.","authors":"P Sleight,&nbsp;P Fox,&nbsp;R Lopez,&nbsp;D E Brooks","doi":"10.1042/cs055381s","DOIUrl":"https://doi.org/10.1042/cs055381s","url":null,"abstract":"<p><p>1. Baroreflex sensitivity was tested in three normal, three borderline and one hypertensive subject before and during mental arithmetic, the prolongation of pulse interval caused by a provoked rise in blood pressure being used as a measure of baroreflex sensitivity. 2. Baroreflex sensitivity was significantly decreased during mental arithmetic. 3. During mental arithmetic the arterial pressure fluctuated markedly. 4. These findings suggest that in man, as well as animals, the defence of alerting reaction depresses baroreflex control and thus contributes to the rise in blood pressure seen at this time.</p>","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"381s-382s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055381s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11495799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 89
Arousal and the circadian rhythm of blood pressure. 觉醒和血压的昼夜节律。
Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055395s
J S Floras, J V Jones, J A Johnston, D E Brooks, M O Hassan, P Sleight
{"title":"Arousal and the circadian rhythm of blood pressure.","authors":"J S Floras,&nbsp;J V Jones,&nbsp;J A Johnston,&nbsp;D E Brooks,&nbsp;M O Hassan,&nbsp;P Sleight","doi":"10.1042/cs055395s","DOIUrl":"https://doi.org/10.1042/cs055395s","url":null,"abstract":"<p><p>1. We have recorded ambulant intra-arterial blood pressure in five normo- and 14 hyper-tensive subjects over 24 h, particular attention being paid to the time of arousal. 2. The data were edited beat-by-beat before storing systolic, diastolic, and mean blood pressure +/- SD for every 2 min period on a computer file. 3. When pooled hourly mean data are plotted there is a rise of 52.9 mmHg systolic and 22.3 mmHg diastolic pressure from 03.00 hours to 11.00 hours in the 14 hypertensive subjects. 4. When the data are plotted in 20 min periods for the hours before and after arousal it is clear that the major rise in pressure occurs abruptly at that time. The 2 h period before arousal shows only a small rise in pressure, i.e. 6.9 mmHg systolic and 2.9 mmHg diastolic. 5. It is suggested that the apparent rapid early morning rise of blood pressure is an artifact of the method of analysis.</p>","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"395s-397s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055395s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11495803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 114
The role of vasopressin in blood pressure control and in experimental hypertension. 加压素在血压控制和实验性高血压中的作用。
Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055251s
P T Pullan, C I Johnston, W P Anderson, P I Korner
{"title":"The role of vasopressin in blood pressure control and in experimental hypertension.","authors":"P T Pullan,&nbsp;C I Johnston,&nbsp;W P Anderson,&nbsp;P I Korner","doi":"10.1042/cs055251s","DOIUrl":"https://doi.org/10.1042/cs055251s","url":null,"abstract":"<p><p>1. The role of vasopressin in blood pressure control and in the pathogenesis of one-kidney Goldblatt hypertension in the conscious dog was investigated. 2. Infusion of synthetic arginine vasopressin to elevate plasma levels approximately five-fold caused bradycardia in normal dogs and increase in mean arterial blood pressure in dogs with pharmacological autonomic blockade. 3. A similar degree of elevation of plasma vasopressin concentration was observed after mild non-hypotensive haemorrhage. 4. Renal artery constriction in unilaterally-nephrectomized dogs caused a rise in plasma renin activity and only a doubling of plasma vasopressin concentration, but a marked rise in mean arterial blood pressure. 5. Vasopressin may play a role in normal cardiovascular homeostatic responses, but its role in the pathogenesis of this form of hypertension is unlikely to be significant.</p>","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"251s-254s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055251s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11496164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 34
The natural history of hypertension in turkeys. 火鸡高血压的自然历史。
Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055213s
A Pagnan, A C Pessina, G Thiene, C Dal Palù
{"title":"The natural history of hypertension in turkeys.","authors":"A Pagnan,&nbsp;A C Pessina,&nbsp;G Thiene,&nbsp;C Dal Palù","doi":"10.1042/cs055213s","DOIUrl":"https://doi.org/10.1042/cs055213s","url":null,"abstract":"<p><p>1. Variables involved in the genesis of hypertension in male broad-breasted white turkeys include social environment, obesity and high salt intake. 2. The hypertension is characterized by low plasma renin activity and, with increasing age, normal to high plasma aldosterone. 3. Medionecrosis of the abdominal aorta is a common pathological finding. 4. The absence of atherosclerotic plaques is probably related to the high concentrations of alpha-lipoproteins.</p>","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"213s-215s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055213s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11496268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Antihypertensive therapy in patients above age 60 years (Fourth Interim report of the European Working Party on High Blood pressure in Elderly: EWPHE). 60岁以上患者的抗高血压治疗(欧洲老年高血压工作组第四次中期报告:EWPHE)。
Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI: 10.1042/cs055263s
A Amery, P Berthaux, W Birkenhäger, A Boel, P Brixko, C Bulpitt, D Clement, F De Padua, M Deruyttere, A De Schaepdryver, C Dollery, R Fagard, F Forette, J Forte, J F Henry, J Hellemans, A Koistinen, U Laaser, P Lund-Johansen, J MacFarlane, P Miguel, A Mutsers, A Nissinen, O T Ohm, W Pelemans, A I Suchett-Kaye, J Tuomilehto, J Willems, P Willemse
{"title":"Antihypertensive therapy in patients above age 60 years (Fourth Interim report of the European Working Party on High Blood pressure in Elderly: EWPHE).","authors":"A Amery,&nbsp;P Berthaux,&nbsp;W Birkenhäger,&nbsp;A Boel,&nbsp;P Brixko,&nbsp;C Bulpitt,&nbsp;D Clement,&nbsp;F De Padua,&nbsp;M Deruyttere,&nbsp;A De Schaepdryver,&nbsp;C Dollery,&nbsp;R Fagard,&nbsp;F Forette,&nbsp;J Forte,&nbsp;J F Henry,&nbsp;J Hellemans,&nbsp;A Koistinen,&nbsp;U Laaser,&nbsp;P Lund-Johansen,&nbsp;J MacFarlane,&nbsp;P Miguel,&nbsp;A Mutsers,&nbsp;A Nissinen,&nbsp;O T Ohm,&nbsp;W Pelemans,&nbsp;A I Suchett-Kaye,&nbsp;J Tuomilehto,&nbsp;J Willems,&nbsp;P Willemse","doi":"10.1042/cs055263s","DOIUrl":"https://doi.org/10.1042/cs055263s","url":null,"abstract":"","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"263s-270s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055263s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11575147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 41
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信