Michelle Goodrick, Eleazar Samuel Kolosovas-Machuca, Edgar Guevara
{"title":"Yoga Asana Increases Prefrontal Cortex Activity and Reduces Resting-State Functional Connectivity.","authors":"Michelle Goodrick, Eleazar Samuel Kolosovas-Machuca, Edgar Guevara","doi":"10.1159/000545381","DOIUrl":"10.1159/000545381","url":null,"abstract":"<p><strong>Introduction: </strong>Various aspects of yoga have been researched for their psychological benefits, yet the neurological mechanisms underlying physical yoga postures (asana) remain inadequately explored due to limitations in prior neuroimaging techniques. The prefrontal cortex (PFC) has been established as an important region of interest concerning psychological health. Therefore, this study aimed to characterize changes in the PFC before, during, and after asana by applying the functional near-infrared spectroscopy (fNIRS) mobile neuroimaging technique.</p><p><strong>Methods: </strong>Twenty-seven healthy adults completed two 6-min, task-independent resting states before and after a 23-min asana routine. With the fNIRS device positioned on the frontal region of the skull, PFC activity was measured during each asana and resting state. The block design involved alternating between three active postures and one control posture. Each active posture was performed for 30 s and repeated 8 times, while the control posture was held during inter-trial intervals lasting 25-30 s. Across the session, this block design resulted in a total of 24 active blocks (8 repetitions of each active posture) and 25 baseline blocks (control posture intervals).</p><p><strong>Results: </strong>All three active asanas significantly increased PFC activity versus baseline, particularly in the right PFC. Furthermore, analysis of short-term changes in resting-state functional connectivity (rsFC) revealed a significant decrease, primarily in the left medial PFC, a key region of the default mode network (DMN), an area known to exhibit heightened activity in individuals suffering from depression and anxiety.</p><p><strong>Conclusion: </strong>This study provides neurological insight into the effects of yoga asana and supports fNIRS for assessing movement-based practices in real-world settings.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"214-223"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Özge Gedik Toker, Erdem Emre Yilmaz, Büşra Özbay, Elif İlayda Aksakal, Ayşe Güneş Bayir
{"title":"Do Individuals with Vertigo or Dizziness Complaints Have a Tendency to Use Complementary and Alternative Medicine Approaches? A Case-Control Study.","authors":"Özge Gedik Toker, Erdem Emre Yilmaz, Büşra Özbay, Elif İlayda Aksakal, Ayşe Güneş Bayir","doi":"10.1159/000548835","DOIUrl":"10.1159/000548835","url":null,"abstract":"<p><strong>Introduction: </strong>Dizziness and vertigo are prevalent reasons for medical consultation, stemming from various benign and pathological conditions. Although traditional treatments are available, complementary and alternative medicine (CAM) approaches are increasingly sought by patients for almost all diseases. This study aimed to investigate the use of CAM approaches in individuals with and without vertigo/dizziness and to compare the results.</p><p><strong>Methods: </strong>The study enrolled 208 participants, 104 of them had complaints of vertigo/dizziness (patient group) and the remaining were without such symptoms (control group). Participants were queried about used CAM approaches, and study participants underwent vestibular assessment.</p><p><strong>Results: </strong>It was revealed that there was a significant higher prevalence of herbal supplement usage among individuals with vertigo/dizziness complaints compared to without vertigo/dizziness. However, no significant differences were found in the usage of other CAM approaches between the groups. Among CAM users in the patient group, the majority did not aim to alleviate vertigo/dizziness symptoms.</p><p><strong>Conclusions: </strong>This study contributes to understanding CAM utilization patterns among vertigo/dizziness patients and underscores the importance of further research to explore the efficacy and safety of CAM approaches in managing these symptoms. Future studies should take into account socioeconomic and sociocultural factors affecting the use of CAM approaches and should aim to evaluate the effectiveness of specific CAM approaches in the treatment of vertigo/dizziness.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"455-462"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12795526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145279183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cognitive Benefits of Ginseng: A Systematic Review and Meta-Analysis of Changes in Mini-Mental State Examination and Alzheimer's Disease Assessment Scale-Cognitive Subscale Scores.","authors":"Junyeon Kim, Minji Kang, Hyunjung Lim","doi":"10.1159/000547543","DOIUrl":"10.1159/000547543","url":null,"abstract":"<p><strong>Background: </strong>Despite the potential cognitive benefits of ginseng, evidence of its effects on cognitive function remains limited. We aimed to evaluate the association between ginseng and cognitive function in individuals with cognitive or memory impairment including those with subjective memory impairment, mild cognitive impairment, and Alzheimer's disease through a systematic review and meta-analysis of recent randomized controlled trials (RCTs).</p><p><strong>Methods: </strong>We searched six databases: PubMed, Embase, Cochrane Library, Korean Studies Information Service System (KISS), Research Information Sharing Service (RISS), and ScienceON, for RCTs investigating the effects of ginseng on cognitive function up to April 26, 2024. Two independent researchers assessed the methodological quality and risk of bias of the extracted studies. Data were presented as the mean difference (MD) with 95% confidence interval (CI), and a subgroup analysis was performed based on ginseng dosage.</p><p><strong>Results: </strong>Eight studies were included in this meta-analysis. The results suggested that ginseng may have a potential effect on cognitive improvement. Ginseng consumption showed a significant effect on increasing Mini-Mental State Examination scores (MD = 0.68; 95% CI: 0.03, 1.32; p = 0.04; I2 = 66%). For Alzheimer's Disease Assessment Scale-Cognitive Subscale, a significant reduction in scores was observed in both the total (MD = -1.10; 95% CI: -1.82, -0.38; p = 0.003; I2 = 0%) and low-dose groups (MD = -1.09; 95% CI: -1.96, -0.22; p = 0.01; I2 = 0%).</p><p><strong>Conclusion: </strong>Ginseng consumption was found to be beneficial for changes in certain cognitive function-related indicators. However, further research is required to determine the long-term effects of ginseng based on dosage.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"283-295"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144798378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"What a Study Is about Should Be Clear.","authors":"Axel Wiebrecht","doi":"10.1159/000539409","DOIUrl":"10.1159/000539409","url":null,"abstract":"","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"94-95"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141300250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acupuncture Relative to Sham Control in Managing Breast Cancer-Related Hot Flashes: A Meta-Analysis of Randomized Controlled Trials.","authors":"Dao-Fu Xu, Hai-Zhen Zheng, Si-Yu Jiang, Bao-Hao Chen, Han-Lin Zou, Ying-Jie Li, Wen-Zhe Wu, Zheng-Yun Zuo","doi":"10.1159/000547579","DOIUrl":"10.1159/000547579","url":null,"abstract":"<p><strong>Introduction: </strong>Breast cancer is the leading cause of morbidity and mortality among female cancers globally. Hot flashes are among the most bothersome complications in women with breast cancer. Acupuncture is a common complementary approach for cancer worldwide. Here we aimed to determine the differential effect between acupuncture and sham acupuncture on hot flashes among breast cancer patients.</p><p><strong>Methods: </strong>Eight English and Chinese databases through 10 October 2024, such as PubMed, Cochrane Library, ScienceDirect, Web of Science, etc., were searched to identify the randomized controlled trials (RCTs) about acupuncture relative to sham control treating breast cancer patients experiencing hot flashes. Outcomes included hot flash frequency per day, hot flash severity score, quality of life related to hot flashes, response rate. Continuous variables and categorical ones were expressed as standardized mean difference (SMD) or MD, and risk ratio (RR), with 95% confidence interval (CI), respectively, for meta-analysis. Sensitivity analysis and Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) of evidence were conducted additionally.</p><p><strong>Results: </strong>Eight RCTs involving 493 participants were included. Relative to sham control, acupuncture was significantly more efficacious in improving the quality of life of breast cancer patients experiencing hot flashes (165 participants, SMD [95% CI]: -1.01 [-1.99, -0.03], I2 = 88%, p = 0.04) at the end of treatment, as well as at follow-up of over 3 months (59 participants, MD [95% CI]: -3.38 [-4.83, -1.93]). With respect to response rate, acupuncture achieved a higher rate versus sham acupuncture (118 subjects, RR [95% CI]:2.66 [1.63, 4.36], I2 = 0, p < 0.0001). Sensitivity analysis solely supported the statistically significant difference between the two groups in terms of response rate (RR [95% CI]: 2.14 [1.03, 4.44]) or 3.20 [1.64, 6.23]). As for frequency and hot flash severity, no difference was noted between groups. GRADE of evidence showed low to very low quality.</p><p><strong>Conclusions: </strong>Acupuncture reached a significantly higher response rate compared to sham control in breast cancer patients with hot flashes, whereas its efficacy on the quality of life showed inconsistency. Given significant heterogeneity and low quality of evidence, future large-sample-size and high-quality RCTs are warranted.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"387-401"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145039193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mechanisms of Traditional Chinese Medicine in Advanced Gastric Cancer: Insights from Meta-Analysis and Network Pharmacology.","authors":"Zhenzheng Zhu, Yuhan Fu, Qingyang Liu, Leitao Sun, Jieru Yu, Ying Zhu","doi":"10.1159/000548562","DOIUrl":"10.1159/000548562","url":null,"abstract":"<p><strong>Background: </strong>Traditional Chinese medicine (TCM) is widely used as an adjuvant therapy for advanced gastric cancer (AGC), yet its underlying mechanisms and targets remain inadequately characterized.</p><p><strong>Methods: </strong>This study integrated meta-analysis and network pharmacology to evaluate the therapeutic effects of TCM, identify core-effective prescriptions (CEPs), and predict potential molecular targets.</p><p><strong>Results: </strong>Seventeen studies comparing TCM combined with chemotherapy versus chemotherapy alone for AGC were identified through a search of seven databases. Meta-analysis showed that TCM significantly improved overall survival (OS) (hazard ratio: 1.65, 95% confidence interval: 1.23-2.22, p < 0.001, I2 = 0%). CEPs and their chemical constituents were identified. A component-target (C-T) network was constructed, revealing the top 10 core genes were TP53, AKT1, CASP3, MYC, IL6, ESR1, EGFR, TNF, PTEN, and HIF1A.</p><p><strong>Conclusion: </strong>This meta-analysis demonstrates that TCM combined with chemotherapy improves OS in AGC patients more effectively than chemotherapy alone. Network pharmacology offered complementary mechanistic insights, laying a foundation for future experimental research.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"402-418"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring Yoga Immersion and Gratitude as Pathways to Enhanced Well-Being.","authors":"Carolin Nögel, Mario Wenzel, Thomas Kubiak","doi":"10.1159/000545916","DOIUrl":"10.1159/000545916","url":null,"abstract":"<p><strong>Introduction: </strong>The popularity of yoga practice is steadily increasing. Previous studies have highlighted numerous beneficial effects of yoga. The present study aimed to investigate gratitude as a mediator of the relationship between yoga and well-being. Additionally, we examined the role of the involvement in yoga philosophy.</p><p><strong>Methods: </strong>A total of 344 yoga practitioners aged between 19 and 87 years completed an online survey. Yoga practice was operationalized via the frequency of practice in days per week. The Yoga Immersion Scale was used to measure the respondents' involvement in yoga philosophy.</p><p><strong>Results: </strong>We found positive associations between yoga frequency and well-being and between gratitude and well-being. There was no evidence for the hypothesized mediating effect of gratitude. Furthermore, yoga immersion did neither moderate the direct relationship between yoga and well-being nor the indirect relationship via gratitude; however, significant correlations between yoga immersion and gratitude and between yoga immersion and well-being were found.</p><p><strong>Conclusion: </strong>The results underscore the relevance of yoga immersion for yoga practice, but at the same time, new questions arise, particularly concerning the role of gratitude. Future research is needed to further gain a better understanding of these relationships.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"187-194"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhanxiang Lin, Dacun Wang, Xiaoyang Fei, Dongmiao Han, Zicai Liu
{"title":"Effect of Abdominal Massage on Constipation: A Systematic Review and Meta-Analysis of Randomized Controlled Studies.","authors":"Zhanxiang Lin, Dacun Wang, Xiaoyang Fei, Dongmiao Han, Zicai Liu","doi":"10.1159/000548699","DOIUrl":"10.1159/000548699","url":null,"abstract":"<p><strong>Background: </strong>Constipation is a common gastrointestinal disease that seriously affects quality of life. Although abdominal massage (AM) has shown some therapeutic effects in some clinical practices, high-quality evidence on AM treating constipation is still scarce.</p><p><strong>Objective: </strong>This systematic review and meta-analysis aimed to thoroughly investigate the efficacy and safety of AM treatment for constipation.</p><p><strong>Methods: </strong>According to the PRISMA guidelines, we searched the PubMed, Web of Science, Cochrane Library, Embase, and Scopus databases for English-language studies published up to July 2025. We searched for randomized controlled trials (RCTs) investigating AM for constipation and screened them according to predefined inclusion and exclusion criteria. The risk of bias was assessed using the Cochrane Collaboration tool (RevMan 5.30). Heterogeneity among trials was measured using the I2 statistic. Effect sizes were expressed as standardized mean difference (SMD) and 95% confidence intervals (CI). Additionally, sensitivity analyses, subgroup analyses, and meta-regression analyses were conducted to further explore sources of heterogeneity.</p><p><strong>Results: </strong>A total of 25 RCTs published from 2009 to 2024 involving 1,508 subjects were included after screening, of which 19 were included in the meta-analysis. The overall risk of bias in the included studies was low. Our findings demonstrated that AM significantly improved constipation severity in patients with constipation (SMD = -1.64, 95% CI = [-2.26, -1.01], p < 0.00001); quality of life (SMD = -1.71, 95% CI = [-2.31, -1.11], p < 0.00001); number of bowel movements per week (SMD = 1.17, 95% CI = [0.70, 1.65], p < 0.00001); stool consistency (SMD = 1.2, 95% CI = [0.05, 2.36], p = 0.04); and pain intensity associated with constipation (SMD = -1.26, 95% CI = [-1.74, -0.77], p < 0.00001). Subgroup analyses further indicated that even short-term AM interventions may positively impact on patients with constipation. Additionally, regarding safety, most included trials did not report adverse events.</p><p><strong>Conclusion: </strong>AM is safe and effective in the treatment of constipation. Although the results of sensitivity analysis and subgroup analysis provide important guidance for clinical selection of AM treatment options, these results need to be interpreted with caution given the diversity of constipation etiologies.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"522-541"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145488129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Auricular Acupressure on Myopia Prevention among Children Aged 6-12 Years with Pre-Myopia in China: Study Protocol of a Prospective Multi-Center Randomized Controlled Trial.","authors":"Jianquan Wang, Yipeng Shi, Xin Yan, Xinru Wu, Ke'er Cao, Luquan Chen, Jun Liu, Hua Peng, Chunxia Li, Liqun Chu, Danlei Wu, Shangkun Zhou, Yingxin Yang, Yangzhong Wang, Xinquan Liu, Jike Song, Fengming Liang, Jing Yao, Zhihua Shen, Fengmei Zhang, Xiaolei Yao, Tao Zuo, Wei Shi, Wujun Li, Xinyue Hou, Zefeng Kang","doi":"10.1159/000542442","DOIUrl":"10.1159/000542442","url":null,"abstract":"<p><strong>Background: </strong>The increasing prevalence of myopia among Chinese children and adolescents, especially at younger ages, has emerged as a significant concern in recent years. Pre-myopia is a key period for myopia prevention and control in children and adolescents. Previous studies suggested auricular acupressure (AA) therapy might offer a viable approach to prevent and slow down myopia progression. Nonetheless, these studies lack robust, high-quality, large-scale, multi-center evidence to conclusively support such assertions. The purpose of this research is to evaluate the efficacy, safety, and economic benefits of AA therapy in preventing myopia in Chinese children aged 6-12 years with pre-myopia.</p><p><strong>Methods: </strong>The single-blind, multi-center, parallel-group, randomized controlled trial will involve 318 pre-myopic children from 20 different centers across China. After recruitment, these participants will be randomly assigned to two groups (the AA group and the control group) at a 1:1 ratio. The AA group will receive auricular point sticking therapy along with health education for a period of 24 weeks, while the control group will be provided the sham AA treatment and routine health education. The assessments of outcomes will be conducted at the start of this study, and then after 4, 8, 12, and 24 weeks. The primary outcome is the change in spherical equivalent refraction at various follow-up times. The secondary outcomes include the number of myopia cases, uncorrected visual acuity, axial length, corneal curvature radius, accommodation amplitude, retinal and choroidal thickness, and eye behavior management. In addition, the cost-effectiveness analysis will be used as the evaluation index for economic assessment.</p><p><strong>Discussion: </strong>The results of this research will provide evidence on the efficacy, safety, and economic benefits of AA therapy in preventing myopia among children aged 6-12 years with pre-myopia in China.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"3-12"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of Static Magnetic Field Therapy on Pain Intensity, Functional Disability, Sleep Quality, and Depressive Symptoms in Patients with Mechanical Neck and Low Back Pain.","authors":"Onur Serdar Gencler, Duran Berker Cemil","doi":"10.1159/000542327","DOIUrl":"10.1159/000542327","url":null,"abstract":"<p><strong>Introduction: </strong>Mechanical neck pain (MNP) and mechanical low back pain (MLBP) can have a negative impact on the quality of life of patients and may be associated with high levels of disability. Magnetic field therapy has been used in the treatment of various diseases. This study was conducted to assess the effects of static magnetic field therapy generated by neodymium magnets in patients with MNP and MLBP.</p><p><strong>Methods: </strong>In this randomized, double-blind, sham-controlled, crossover study, patients with MNP and MLBP were randomly assigned to either the magnetic band or sham band treatment groups. After the initial 2-week phase (with participants randomly assigned to either treatment or sham control), both groups underwent a 1-week washout period. Subsequently, the groups were swapped and proceeded with a second 2-week phase. Visual analogue scale (VAS), Oswestry Low Back Pain Disability Questionnaire (ODI), Neck Disability Index (NDI), Insomnia Severity Index (ISI), and Patient Health Questionnaire-9 (PHQ-9) were used to evaluate the patients' pain severity, functional disability, sleep quality, and levels of depressive symptoms, respectively.</p><p><strong>Results: </strong>Of the 30 subjects, 17 (56.7%) had MLBP, whereas 13 (43.3%) had MNP. Magnetic band treatment (MBT) resulted in a significant decrease in the VAS score (p < 0.001) in all patients. MBT led to a significant decrease in the ODI score (p = 0.009) in patients with MLBP. A significant decrease in the NDI score was found in MBT (p < 0.001) in patients with MNP. The improvement in ISI and PHQ-9 scores was also significantly higher in MBT (p < 0.001).</p><p><strong>Conclusion: </strong>For patients with MNP and MLBP who have not experienced sufficient benefits from conventional treatments, neodymium magnets can be considered as an alternative treatment option due to their significant properties.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"45-54"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}