Contact Dermatitis最新文献

{"title":"Patch Testing in Individuals With Diabetes Using Medical Devices. Part 1-Contact Allergy to Baseline Series Allergens.","authors":"Thanisorn Sukakul, Josefin Ulriksdotter, Martin Mowitz, Magnus Bruze, Nils Hamnerius, Cecilia Svedman","doi":"10.1111/cod.70117","DOIUrl":"10.1111/cod.70117","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of contact allergy in individuals with diabetes and diabetes medical device (MD) users is unknown.</p><p><strong>Objectives: </strong>This study (Part 1 and 2) aims at describing contact allergy prevalences in diabetes MD users.</p><p><strong>Methods: </strong>Adults with type 1 diabetes from two endocrinology departments were patch tested with the Swedish baseline series (SBS) and a MD series. Contact allergies to the baseline series were compared with consecutive dermatitis patients. Detailed results for the MD series are presented in another manuscript.</p><p><strong>Results: </strong>Overall, similar contact allergy prevalences to the SBS were seen in the 204 individuals with diabetes (114 with rash to diabetes MDs, 90 without) and 1382 controls (34.3% vs. 39.6%, adjusted p value = 0.30). The prevalence of sesquiterpene lactone mix allergy was higher in the individuals with diabetes vs. dermatitis controls (2.5% vs. 0.3%, adjusted p value = 0.0011). Contact allergy to Myroxylon pereirae resin (MP) was overrepresented in individuals with diabetes versus controls (8.3% vs. 3.8%, adjusted p value = 0.0033) but not in individuals with diabetes with rash to diabetes MDs vs. without.</p><p><strong>Conclusions: </strong>Contact allergy to the SBS is common in diabetes MD users. The cause of the overrepresentation of MP allergy needs to be further elucidated.</p>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":"624-634"},"PeriodicalIF":4.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13139702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146225741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occupational Allergic Contact Dermatitis to Methylisothiazolinone in an Engobe Ceramic Decorator.","authors":"Paolo Antonio Danza, Giulia Ciccarese, Françoise Giordano-Labadie, Teresa Nocera, Caterina Foti","doi":"10.1111/cod.70126","DOIUrl":"10.1111/cod.70126","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":"694-696"},"PeriodicalIF":4.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13139699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147480044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occupational Airborne Allergic Contact Dermatitis From UV-Curing Printing Varnish.","authors":"Magalie Coco-Viloin, Caroline Gernigon, Fabrice Herin","doi":"10.1111/cod.70115","DOIUrl":"10.1111/cod.70115","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":"697-699"},"PeriodicalIF":4.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13139695/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147343935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Allergic Contact Dermatitis on Health-Related Quality of Life: A Cross-Sectional Case-Control Study in a Spanish Population.","authors":"Francisco José Navarro-Triviño, Álvaro Prados-Carmona, Ricardo Ruiz-Villaverde, María Isabel Peralta-Ramírez","doi":"10.1111/cod.70116","DOIUrl":"10.1111/cod.70116","url":null,"abstract":"<p><strong>Background: </strong>Allergic contact dermatitis (ACD) is a chronic inflammatory skin disorder associated with substantial impairment in quality of life (QoL). Few studies have comprehensively assessed the multidimensional impact of ACD using validated QoL instruments and healthy controls.</p><p><strong>Objectives: </strong>To evaluate the impact of ACD on QoL compared to a control group and to explore the association between clinical variables and patient-reported outcomes.</p><p><strong>Methods: </strong>This cross-sectional study included 225 patients with confirmed ACD (positive and clinically relevant patch tests) and 225 healthy controls. All participants completed the Dermatology Life Quality Index (DLQI), the EuroQoL-5D (EQ-5D-5L) and the Skindex-29. Disease severity was assessed using the modified Investigator's Global Assessment (mIGA). Statistical analyses included nonparametric Mann-Whitney U tests for between-group comparisons, correlation analyses, and multivariate linear and ordinal regression models to identify predictors of quality-of-life impairment.</p><p><strong>Results: </strong>Patients with ACD showed significantly greater impairment across all QoL measures compared to controls (p < 0.001). Pruritus was the most frequently reported symptom (45.0%), and emotional distress and functional limitations were prominent. Higher mIGA scores were significantly associated with poorer QoL across all instruments.</p><p><strong>Conclusions: </strong>ACD has a marked negative impact on multiple dimensions of QoL, comparable to that observed in other chronic dermatoses. These findings underscore the importance of integrating standardised QoL assessments into the routine management of ACD and support the adoption of multidimensional approaches in both clinical evaluation and therapeutic decision-making, while also highlighting the relevance of psychosocial screening as an essential component of comprehensive patient care.</p>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":"592-602"},"PeriodicalIF":4.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13139706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147270060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epicutaneous and Drug Provocation Testing in Severe Cutaneous Adverse Reactions: A 20-Year Single-Centre Experience.","authors":"Zohra Chadli, Khadija Mansour, Ghada Jaouahdou, Manel Ben Belgacem, Yosra Soua, Nadia Ben Fredj, Jameleddine Zili, Haifa Ben Romdhane, Karim Aouam","doi":"10.1111/cod.70118","DOIUrl":"10.1111/cod.70118","url":null,"abstract":"<p><strong>Background: </strong>Identifying and discontinuing the offending drug(s) in severe cutaneous adverse drug reactions (SCARs) can be particularly challenging, especially in polymedicated patients. For many years, patch tests (PTs) were considered the only safe and reliable method for investigating SCARs. However, intradermal tests (IDTs), once thought to be contraindicated, have recently garnered increasing interest. Similarly, oral provocation tests, previously avoided due to safety concerns, are now being more frequently employed in SCAR assessment.</p><p><strong>Methods: </strong>We analysed SCARs reported at Monastir University Hospital. Allergy work-up included PTs, IDTs and oral provocation tests, with evaluation of cross-reactivity, co-sensitisation and neo-sensitization.</p><p><strong>Results: </strong>We identified 190 SCAR episodes in 188 patients. DRESS was most frequent (75%), followed by AGEP (19%) and SJS/TEN (6%). Causative drugs were identified in 97.9% of cases, mainly anti-infectives. Skin tests were conducted in 69.5% of patients, yielding positivity rates of 49% for PTs and 77% for IDTs in DRESS, and 52% and 66%, respectively, in AGEP. Cross-reactivity was noted in 7% of DRESS and 11.1% of AGEP, while neo-sensitization was documented in 32.5% of DRESS patients.</p><p><strong>Conclusion: </strong>Allergological investigations are valuable tools in SCAR management, enabling identification of culprit drugs, assessment of cross-reactivity, detection of neo-sensitization and selecting safe alternatives.</p>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":"677-688"},"PeriodicalIF":4.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13139704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146225765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Allergic Risk of Moisturising Cosmetic Products: A Study on the Composition of 300 Products Commercialised in Tunisia.","authors":"Dalel Kemicha, Ines Lahouel, Belhadjali Hichem, Soua Yosra, Youssef Monia, Zili Jameleddine","doi":"10.1111/cod.70096","DOIUrl":"10.1111/cod.70096","url":null,"abstract":"<p><strong>Background: </strong>Moisturising cosmetic products (MCP) formulations may contain ingredients known to trigger allergic contact dermatitis. Claims such as 'hypoallergenic' or 'fragrance-free' are commonly used in marketing, yet these terms are not consistently regulated, potentially posing a risk for patients with allergic contact dermatitis.</p><p><strong>Objectives: </strong>To assess the allergenic potential of moisturisers by analysing their ingredients and determining the prevalence of contact allergens.</p><p><strong>Methods: </strong>A survey conducted between April and June 2023. MCPs were collected from supermarkets and pharmacies. Data analysis focused on allergen prevalence and product origin. All products were systematically screened for seven targeted allergenic components by reviewing their ingredient labels (INCI): isothiazolinones, phenoxyethanol, formaldehyde and its releasers, lanolin, fragrances, parabens and propylene glycol. All allergens included in our study were systematically searched for all relevant synonyms in both English and French.</p><p><strong>Results: </strong>Three hundred products were analysed, including 153 items (51%) from supermarkets and 147 (49%) from pharmacies. Fragrances were the most frequently identified allergens, present in 84.7% of formulations. Only 15.3% of products were free from fragrances and plant extracts. Among those labelled 'fragrance-free', 86.8% (46 of 53) were truly free of fragrances. Isothiazolinones were found in 7% of products, predominantly in leave-on formulations and locally manufactured brands. Formaldehyde-releasing agents were detected in 10.3% of products, with higher prevalence in supermarkets and leave-on items. Parabens were present in 10.7%, including two products with hydroxybenzoate. Propylene glycol was identified in 28% of products; still, 24.3% (18 of 74) of hypoallergenic-labelled products contained it. Phenoxyethanol appeared in 37.7% of formulations and was more common in supermarket-sold products. Lanolin was found in 2.7% of the products.</p><p><strong>Conclusion: </strong>The study highlights a high prevalence of contact allergens in MCPs, including those marketed as hypoallergenic.</p>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":"645-651"},"PeriodicalIF":4.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146200487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occupational Asthma and Contact Urticaria in a Wildlife Worker With Type I Hypersensitivity to Deer Dander.","authors":"Eglė Janušonytė, Thomas Harr, Peter Jandus, Haïg Nigolian","doi":"10.1111/cod.70136","DOIUrl":"10.1111/cod.70136","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":"717-719"},"PeriodicalIF":4.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13139696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147490420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pustular Allergic Contact Dermatitis Caused by Occult Nickel Exposure From Pain Relief Pads.","authors":"Ella Dendooven, Katrien Goos, Olivier Aerts","doi":"10.1111/cod.70130","DOIUrl":"10.1111/cod.70130","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":"703-705"},"PeriodicalIF":4.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147354116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How Good Is the Australian Paediatric Baseline Series at Detecting Allergic Contact Dermatitis?","authors":"James Fuller, Amanda Palmer, Claire Grills, Rosemary Nixon","doi":"10.1111/cod.70125","DOIUrl":"10.1111/cod.70125","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":"712-713"},"PeriodicalIF":4.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147364035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contact Urticaria to Chamois ( Rupicapra rupicapra ) Raw Muscle Meat in a Non-Occupational Hunter: First Documented Case.","authors":"Milad Noori, Marie-Charlotte Brüggen, Peter Schmid-Grendelmeier, Matthias Möhrenschlager","doi":"10.1111/cod.70131","DOIUrl":"10.1111/cod.70131","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":"714-716"},"PeriodicalIF":4.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147372182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}