Contact Dermatitis最新文献_第2页

Prevalence of Contact Allergy to Rubber Accelerators From the European Baseline Series in Dermatitis Patients: A Systematic Review and Meta-Analysis. 来自欧洲基线系列的皮炎患者对橡胶促进剂接触性过敏的患病率：系统回顾和荟萃分析。

IF 4.6 1区医学

Contact Dermatitis Pub Date : 2025-09-08 DOI: 10.1111/cod.70024

Daniel Isufi, Christoffer Kursawe Larsen, Mikkel Bak Jensen, Kian Karimian, Claus Zachariae, Jakob Ferløv Baselius Schwensen, Farzad Alinaghi, Jeanne Duus Johansen

{"title":"Prevalence of Contact Allergy to Rubber Accelerators From the European Baseline Series in Dermatitis Patients: A Systematic Review and Meta-Analysis.","authors":"Daniel Isufi, Christoffer Kursawe Larsen, Mikkel Bak Jensen, Kian Karimian, Claus Zachariae, Jakob Ferløv Baselius Schwensen, Farzad Alinaghi, Jeanne Duus Johansen","doi":"10.1111/cod.70024","DOIUrl":"https://doi.org/10.1111/cod.70024","url":null,"abstract":"Rubber accelerators are chemicals used as vulcanizers in the production of rubber items and may cause contact allergy (CA). The aim of this study was to assess the worldwide prevalence of CA to rubber accelerators from the European baseline series among dermatitis patients. A comprehensive literature search across PubMed, Embase, and Web of Science yielded 106 studies with 826 543 individuals patch tested between 1984 and 2023. Meta-analysis showed pooled prevalence rates of 2.55% for thiuram mix, 0.86% for mercapto mix, and 0.83% for mercaptobenzothiazole. Marked geographical variations were observed: North America and Asian regions showed the highest prevalences whereas Europe had lower rates. Comparisons before and after the year 2000 revealed a decline in CA to all three accelerators. Sub-analysis of the extended rubber series revealed the prevalence of CA to tetraethylthiuram disulphide of 3.73% and to zinc diethyldithiocarbamate of 0.60%. The prevalence of CA to carba mix was 3.96%. These findings underscore the public health implications of rubber accelerator-induced CA. Strengthened preventive measures and regulatory efforts, including improved labelling, safe limits of rubber gloves, and reduced use of high-risk accelerators are needed to mitigate disease burden. The results emphasise a need for ongoing surveillance, especially concerning extended rubber series.","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nickel and Cobalt Release From Hairdressing Tools in German Barbershops. 德国理发店美发工具中镍和钴的释放。

IF 4.6 1区医学

Contact Dermatitis Pub Date : 2025-09-07 DOI: 10.1111/cod.70031

Cara Bieck, Kirsten Koopmann, Antje Alberts, Valeska Buder, Grita Schedlbauer, Albert Nienhaus, Christoph Skudlik, Swen Malte John

{"title":"Nickel and Cobalt Release From Hairdressing Tools in German Barbershops.","authors":"Cara Bieck, Kirsten Koopmann, Antje Alberts, Valeska Buder, Grita Schedlbauer, Albert Nienhaus, Christoph Skudlik, Swen Malte John","doi":"10.1111/cod.70031","DOIUrl":"https://doi.org/10.1111/cod.70031","url":null,"abstract":"Background: Nickel and cobalt release from tools has recently been evidenced in German hairdressing salons. Comparable data were not available for German barbershops.Objectives: Screening of tools for nickel and cobalt release.Methods/materials: One hundred and forty-one tools were tested in six barbershops located in Lower Saxony, Germany. A nickel spot test (reagent: dimethylglyoxime [CAS no. 95-45-4]) and a cobalt spot test (reagent: nitroso-r salt [disodium-1-nitroso-2-naphthol-3,6-disulphonate; CAS no. 525-05-03]) were used.Results: 35 of 141 tools overall (24.8%) released nickel and 3 of 141 tools overall (2.1%) released cobalt. Nickel release was found in 10 of 57 hair clippers, 9 of 13 tweezers, 8 of 11 sectioning clips, 3 of 14 straight shavers, 2 of 32 scissors, 2 of 4 tail combs and 1 of 2 shaving brushes. Cobalt release was detected in 2 of 14 straight shavers and 1 of 11 sectioning clips.Conclusions: Tools in German barbershops have been identified as occupational sources of nickel and cobalt exposure. Nickel release was observed more frequently. Therefore, it is recommended that compliance with the EU nickel regulation is observed more strictly. In addition, the importance of measures to protect the skin at work should be communicated to barbers, e.g., within health pedagogical measures.","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145014005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Christmas Tree Hand Dermatitis Caused by Pinecones. 松果引起的圣诞树手皮炎。

IF 4.6 1区医学

Contact Dermatitis Pub Date : 2025-09-01 DOI: 10.1111/cod.70022

Luis Godoy-Villalón, Esmeralda López-Jiménez, Leopoldo Borrego

引用次数: 0

Treatment Willingness and Importance of Skin Clearance for Patients With Chronic Hand Eczema. 慢性手湿疹患者治疗意愿及皮肤清除率的重要性。

IF 4.6 1区医学

Contact Dermatitis Pub Date : 2025-08-30 DOI: 10.1111/cod.70013

Maria O Christensen, Lea K Nymand, Caroline Meyer Olesen, Silvia Mariel Ferrucci, Christoph Schlapbach, Swen Malte John, Sonja Molin, Claus Zachariae, Simon F Thomsen, Jacob P Thyssen, Alexander Egeberg

{"title":"Treatment Willingness and Importance of Skin Clearance for Patients With Chronic Hand Eczema.","authors":"Maria O Christensen, Lea K Nymand, Caroline Meyer Olesen, Silvia Mariel Ferrucci, Christoph Schlapbach, Swen Malte John, Sonja Molin, Claus Zachariae, Simon F Thomsen, Jacob P Thyssen, Alexander Egeberg","doi":"10.1111/cod.70013","DOIUrl":"https://doi.org/10.1111/cod.70013","url":null,"abstract":"Background: Chronic hand eczema (CHE) has a significant negative impact on quality of life and a high disease burden.Objective: To investigate the importance of skin clearance and daily time trade off (dTTO) in adult patients with CHE.Methods: Patients with CHE from the Danish Skin Cohort were sent a digital survey regarding demographics, lifestyle factors, CHE characteristics, importance of obtaining skin clearance, and dTTO.Results: Of 372 patients with current CHE, 58.1%, 26.3%, 11.0%, and 4.6% reported having mild, moderate, severe, and very severe CHE, respectively. Patients reported a median of 9 (interquartile range: [5-10], 9 [7-10], 10 [8-10] and 10 [9-10]) when asked about the importance of obtaining 50%, 75%, 90%, and 100% skin clearance, respectively (numerical rating scale from 0 [lowest] to 10 [highest]). Importance of skin clearance increased with increasing CHE severity (p < 0.001). One in three patients (41.2%) with either severe or very severe CHE was willing to allocate > 1 h a day to treat their CHE.Conclusions: Skin clearance was important among CHE patients, and patients with more severe disease were willing to allocate a substantial amount of time every day to treat their CHE.","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Allergic Contact Dermatitis to Colophonium in a 'Carnival Mask'. 嘉年华面具中Colophonium的过敏性接触性皮炎。

IF 4.6 1区医学

Contact Dermatitis Pub Date : 2025-08-28 DOI: 10.1111/cod.70020

Gabriela Blanchard, Olivier Sorg, Pierre Piletta-Zanin

引用次数: 0

CHEMIN-Results From the National Practice Survey in Chronic Hand Eczema Therapeutic Management. chemin -全国慢性手部湿疹治疗管理实践调查结果。

IF 4.6 1区医学

Contact Dermatitis Pub Date : 2025-08-28 DOI: 10.1111/cod.70015

Claire Bernier, Marie-Noëlle Crépy, Bruno Halioua, Camille Leleu, Marina Schverer, Solenn Le Clanche, Marie Tauber, Angèle Soria

引用次数: 0

Evaluation of Artificial Intelligence-Assisted Diagnosis of Skin Erythema in a Patch Test. 人工智能辅助诊断皮肤红斑斑试验的评价。

IF 4.6 1区医学

Contact Dermatitis Pub Date : 2025-08-27 DOI: 10.1111/cod.70011

Seoyoung Kim, Hyunsik Hwang, Mihyun Oh, Jieun Han, Sodam Park, Soyoung Lee, Goun Kim, Sungwon Cho, Dong Hun Lee, Jae Youl Cho

{"title":"Evaluation of Artificial Intelligence-Assisted Diagnosis of Skin Erythema in a Patch Test.","authors":"Seoyoung Kim, Hyunsik Hwang, Mihyun Oh, Jieun Han, Sodam Park, Soyoung Lee, Goun Kim, Sungwon Cho, Dong Hun Lee, Jae Youl Cho","doi":"10.1111/cod.70011","DOIUrl":"https://doi.org/10.1111/cod.70011","url":null,"abstract":"Background: The patch test evaluates skin erythema, infiltration, papules and vesicles following exposure to various substances, including metals, cosmetics and medicines. Accurate evaluation of these conditions requires consistent skin score assessments, precise visual grading and minimal inter-expert variability.Objectives: This study aimed to develop a skin irritation artificial intelligence model based on the YOLOv5x object detection framework to automatically detect skin irritation from the patch test images for multiple test substances.Methods: Patch test images were collected with test sites marked to enable the YOLOv5x algorithm to locate the samples. An expert assigned a score to each sample (0-4) for training and validation. The model was trained using 83 629 data points. Evaluation and validation were performed with 1312 and 1536 data points, respectively.Results: The model achieved an overall accuracy of 0.983 at both 24 and 48 h, with an F1 score (harmonic mean of recall and precision) of 0.982. The areas under the curve (AUCs) for scores 0, 1 and 2 were 0.914, 0.838 and 0.865, respectively. The sensitivity for a score of 0 was 0.997.Conclusion: These findings suggest that this AI model effectively supports and classifies skin irritation, thereby facilitating faster and more accurate dermatological evaluations.","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potential Allergens in Medical Adhesives in Tapes, Wound Dressings, and Ostomy Care: A Scoping Review. 医用胶粘剂在胶带、伤口敷料和造口护理中的潜在过敏原：范围综述。

IF 4.6 1区医学

Contact Dermatitis Pub Date : 2025-08-26 DOI: 10.1111/cod.70016

An Goossens, Olivier Aerts, Ella Dendooven

{"title":"Potential Allergens in Medical Adhesives in Tapes, Wound Dressings, and Ostomy Care: A Scoping Review.","authors":"An Goossens, Olivier Aerts, Ella Dendooven","doi":"10.1111/cod.70016","DOIUrl":"https://doi.org/10.1111/cod.70016","url":null,"abstract":"Background: Medical adhesives are increasingly reported, although still underestimated as causes of allergic contact dermatitis, for which identification of the sensitising culprits is often impossible, mainly because of non-declaration of components on medical device packaging and lack of cooperation from manufacturers.Objectives: To report on the allergens identified in medical adhesives in tapes, wound dressings, and ostomy care.Methods: The relevant literature (1980-2024) on sensitization sources and allergens was analysed and the results reported.Conclusion: The main reported contact allergens present as tackifiers in the production of medical adhesive tapes and wound dressings are colophonium and derivatives, (meth)acrylates and isocyanates. 2-HEMA is a screening agent for contact allergy to acrylics, though other derivatives are important as well. Unexpectedly, d-limonene and other fragrance components were identified in so-called 'hypoallergenic', 'non-latex', or 'non-colophonium' containing materials, even in some types of colophonium itself. In ostomy adhesive pastes, besides colophonium and (meth)acrylates, various PMV/MA copolymer esters with different alkyl chain lengths (Gantrez-ES derivatives) are frequent sensitizers.","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Occupational Allergic Contact Dermatitis Resembling Angioedema Induced by Acrylates in a Pipe Relining Worker. 一名管道铺设工人的职业性过敏性接触性皮炎，类似丙烯酸酯引起的血管性水肿。

IF 4.6 1区医学

Contact Dermatitis Pub Date : 2025-08-26 DOI: 10.1111/cod.70023

Joanna Szumniak, Jakob Dahlin, Annarita Antelmi

引用次数: 0

Caprylyl Glycol, a Trending and Highly Relevant Sensitiser in Cosmetics That Needs to be Patch Tested Separately. 丙二醇，化妆品中的一种趋势和高度相关的致敏剂，需要单独进行贴片测试。

IF 4.6 1区医学

Contact Dermatitis Pub Date : 2025-08-26 DOI: 10.1111/cod.70019

Silada Kanokrungsee, Ella Dendooven, Olivier Aerts

引用次数: 0