Contact Dermatitis最新文献

{"title":"Allergic Contact Dermatitis From Football Shin Guards in a Child With Atopic Dermatitis","authors":"Sergio De Marchi, Emanuela Cecchin, Sergio Umberto De Marchi, Leonardo Alberto Sechi","doi":"10.1111/cod.14746","DOIUrl":"10.1111/cod.14746","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":"92 5","pages":"408-410"},"PeriodicalIF":4.8,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Health Education Based on Pictograms and Video Sequences in the Prevention of Hand Eczema Among Hospital Cleaners: A Cluster-Randomised Controlled Trial With 24 Weeks Follow-Up","authors":"Farnam Barati Sedeh,&nbsp;Anna Glenn Ullum,&nbsp;Karl Bang Christensen,&nbsp;Ole Steen Mortensen,&nbsp;Thórunn Elísabet Michaelsdóttir,&nbsp;Sarah Gharabaghi Stückler,&nbsp;Gregor Borut Ernst Jemec,&nbsp;Kristina Sophie Ibler","doi":"10.1111/cod.14741","DOIUrl":"10.1111/cod.14741","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Hand eczema (HE) is common among hospital cleaners, yet no specific prevention programme exists for this group in Denmark.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate the effectiveness of visual aids (pictograms and video scenes) based on evidence-based skin care and protection recommendations on HE outcomes, focusing on disease severity, point prevalence and skin care and protection knowledge.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A cluster-randomised controlled trial was conducted in professional cleaners from three Danish hospitals. Intervention Group A received pictograms, video clips and a short group-based educational session. Intervention Group B received only pictograms and video clips. The control group received treatment as usual. HE severity and prevalence were assessed clinically, while knowledge was measured using self-reported data.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Out of 234 invited cleaners, 224 (96%) participated (Intervention Group A: 73, Intervention Group B: 78, Control Group: 73). After 24 weeks, both intervention groups showed significant reductions in HE severity and prevalence compared to the control group. Knowledge of skin care and protection also improved significantly in both intervention groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Visual aids effectively reduced HE prevalence and severity in hospital cleaners. Pictograms are a cost-effective strategy that can be widely implemented, addressing the substantial burden of HE in the cleaning industry across diverse settings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":"92 5","pages":"367-379"},"PeriodicalIF":4.8,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Characteristics of Chronic Hand Eczema Among Adults in Denmark: A General Population-Based Study","authors":"David Thein,&nbsp;Julia-Tatjana Maul,&nbsp;Simone Ribero,&nbsp;Jonathan I. Silverberg,&nbsp;Alexander Egeberg,&nbsp;Jacob P. Thyssen","doi":"10.1111/cod.14732","DOIUrl":"10.1111/cod.14732","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The epidemiology of chronic hand eczema (CHE) remains poorly examined.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To investigate the prevalence of CHE in a general adult population and describe the characteristics of affected individuals.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We investigated the prevalence and characteristics of CHE using a random sample from the general Danish population (The Danish Skin Cohort). CHE was defined as eczema on the hands or wrists during a minimum of three consecutive months or reoccurrence of hand eczema at least twice within 12 months.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Out of 11 166 adults, 1306 experienced hand eczema (HE) at some point in their lifetime. Within the last 12 months, 408 (3.7%) experienced HE, of which 332 (81.4%) reported CHE. The crude 1-year period prevalence of CHE was 3.0% (95% confidence interval (CI), 2.7%–3.3%) while the standardised prevalence was 3.5% (95% CI, 3.3%–3.6%). Among adults with CHE, 70.8% were female, and the mean age was 48.0 years (standard deviation 16.6 years). Most individuals with CHE had two relapses (<i>n</i> = 309, 93.1%), while <i>n</i> = 206, 61.1%, had HE for more than 3 months. Compared to HE, CHE was more likely diagnosed by a dermatologist and affect the fingers and back of the hand.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The standardised prevalence was 3.5% (95% CI, 3.3%–3.6%) and 4.2% (95% CI, 4.0%–4.4%) for CHE and HE, respectively. We identified a large overlap between HE and CHE (81.4%) in adults from the general population, indicating that many individuals affected by eczema on the hands may experience a chronic course.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":"92 5","pages":"358-366"},"PeriodicalIF":4.8,"publicationDate":"2025-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantification of Lawsone and p-Phenylenediamine in Natural Henna Products for Hair Colouring Available in Poland","authors":"Edyta Sienkiewicz-Szłapka,&nbsp;Arleta Janysz,&nbsp;Michał H. Wróbel","doi":"10.1111/cod.14739","DOIUrl":"10.1111/cod.14739","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Henna is a powdered plant material traditionally used for medicinal and cosmetic purposes in Asia and the Mediterranean region. In North America and Europe, however, it is only used to colour the hair and decorate the body. This colouring process is due to the action of the secondary metabolite lawsone, which enables henna to produce orange to red shades of colour. The final colour effect of the henna treatment on the hair depends on many factors, including the amount of lawsone in the product used. Unfortunately, there are also henna products on the market that contain the strong allergen para-phenylenediamine (PPD). Henna products whose manufacturers do not inform consumers about the addition of PPD are a particular problem.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The aim of this study was therefore not only the qualitative and quantitative evaluation of lawsone but also of PPD in selected products offered for sale as henna.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Since HPLC assays are one of the most sensitive, rapid and reliable methods for the quality control of herbal raw materials, we developed and validated two independent HPLC methods with UV detection for both analytes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results and Conclusions</h3>\u0000 \u0000 <p>We found that only about 60% of the tested cosmetic products were good quality natural products containing not &lt; 0.5% lawsone (the range was between 0.5% and 1.0%). On the other hand, up to 36% of the henna samples contained PPD (the range was between 1% and 9%), and only three out of five of these products were properly labelled. Unfortunately, most of the henna used by Polish consumers comes from online retailers and can be shipped from different regions of the world. It is difficult to adequately control this market. Therefore, proper consumer education and awareness of the risk of PPD exposure when using henna could also be crucial for the prevention and management of PPD allergy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":"92 4","pages":"261-272"},"PeriodicalIF":4.8,"publicationDate":"2025-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Airborne Allergic Contact Dermatitis Caused by Pao Ferro (Machaerium scleroxylon) in a Guitar Maker","authors":"James Fuller,&nbsp;Rachael Davenport,&nbsp;Amanda Palmer,&nbsp;Rosemary Nixon","doi":"10.1111/cod.14752","DOIUrl":"10.1111/cod.14752","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":"92 5","pages":"419-420"},"PeriodicalIF":4.8,"publicationDate":"2025-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic Gallate Cheilitis With Drug and Dietary Involvement","authors":"Juliette Caron,&nbsp;Florence Libon,&nbsp;Christine Delebarre-Sauvage","doi":"10.1111/cod.14740","DOIUrl":"10.1111/cod.14740","url":null,"abstract":"&lt;p&gt;Allergy to industrial antioxidants has long been considered uncommon, especially to gallates. Only 74 cases of contact allergy to gallates have been reported in the last literature review published in 2017 [&lt;span&gt;1&lt;/span&gt;]. Since then, some recent studies suggest that these allergens are not so rare [&lt;span&gt;2&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;We report the case of a 68-year-old woman having chronic cheilitis evolving for 10 years. Her history was marked by migraines and dyslipidaemia treated by propranolol and Inegy [simvastatin/ezetimibe] (Organon Heist BV, Heist-op-den-Berg, Belgium) respectively for more than 10 years. Clinical examination showed eczema on the lips. She had daily lip itching. We performed patch testing with the European baseline series and cosmetic series from Laboratoire Destaing. The reading was obtained according to the International Contact Dermatitis Research Group criteria. The occlusion time was 48 h according to the European Society of Contact Dermatitis guidelines. The haptens were applied on the back using Finn Chambers. Positive results were found for gallate mix 1% (+) and propyl gallate 1% (+++) at D3 and D12 and for dodecyl gallate 0.25% (+++) and octyl gallate 0.25% (+++) at D12 only (Figure 2). After 1 month of avoiding cosmetics on the face, a partial regression of the cheilitis was noted. We carried out additional assessment due to persistent symptoms (Figure 1). Inegy is a lipid-lowering therapy containing propyl gallate as an excipient. We performed patch testing with Inegy 30% petrolatum and a negative control. The patch test was found positive for Inegy (+) at D7 (Figure 2). Treatment with Inegy combining ezetimibe 10 mg/simvastatin 40 mg was replaced by ezetimibe 10 mg and simvastatin 40 mg separately. These uncombined tablets do not contain propyl gallate. We also advised the patient to stop consuming industrial food products and foods containing vegetable oils, as she did every day. Following this advice, the patient no longer had cheilitis. She had no symptoms at the clinical visit 3 months later. We concluded that the patient had chronic gallate cheilitis with drug and dietary involvement.&lt;/p&gt;&lt;p&gt;In order to treat chronic or recurrent cheilitis, it is important to eliminate an allergy to gallates. This case confirms that patch-test reading at 48 h or 72 h is insufficient to diagnose a sensitization to these molecules, as previously described [&lt;span&gt;3&lt;/span&gt;]. We therefore recommend an additional reading between D7 and D15. The treatment is based not only on avoiding cosmetics containing gallates, but also on avoiding medications and foods containing them. The patient's cheilitis worsened when Locapred 0.1% cream [desonide] (Pierre Fabre medicament production, Gien, France) containing propyl gallate was applied on her mouth. It improved after stopping Inegy and following a diet without industrial food products and vegetable oils. Dietary regulation seems to be necessary for healing, as low doses of propyl gallate can b","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":"92 5","pages":"417-418"},"PeriodicalIF":4.8,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cod.14740","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142920810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simultaneous Immediate and Delayed Hypersensitivity to Galcanezumab—Case Report","authors":"Peter Refki,&nbsp;Aude Belbézier,&nbsp;Marine-Alexia Lefevre,&nbsp;Marc Vocanson,&nbsp;Amandine Mosnier,&nbsp;Martine Pernollet,&nbsp;Marie Tauber,&nbsp;Pauline Pralong","doi":"10.1111/cod.14747","DOIUrl":"10.1111/cod.14747","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":"92 5","pages":"395-397"},"PeriodicalIF":4.8,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"JAK Inhibitors Effect on Diagnostic Patch Testing","authors":"Miguel Antonio Lasheras-Pérez,&nbsp;Javier Miquel-Miquel,&nbsp;Cristina Fernández-Romero,&nbsp;Rafael Botella-Estrada,&nbsp;Mercedes Rodríguez-Serna","doi":"10.1111/cod.14751","DOIUrl":"10.1111/cod.14751","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":"92 5","pages":"387-389"},"PeriodicalIF":4.8,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fixed Drug Eruption due to Chlorpheniramine: Case Report","authors":"Vanesa García Paz,&nbsp;Laura Romero-Sánchez,&nbsp;Benigno Monteagudo-Sánchez,&nbsp;Mónica Castro-Murga,&nbsp;Pilar Iriarte-Sotés","doi":"10.1111/cod.14738","DOIUrl":"10.1111/cod.14738","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":"92 4","pages":"316-317"},"PeriodicalIF":4.8,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imprecise Coding in Allergic Contact Dermatitis: A Register-Study From Northern Finland Between Years 1999 and 2022","authors":"Jenni Kämäräinen,&nbsp;Touko Loukkola,&nbsp;Joanna Mikkola,&nbsp;Minna Sivonen,&nbsp;Jari Jokelainen,&nbsp;Eetu Kiviniemi,&nbsp;Laura Huilaja,&nbsp;Suvi-Päivikki Sinikumpu","doi":"10.1111/cod.14744","DOIUrl":"10.1111/cod.14744","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Registry-based data are increasingly used in dermatological research. A recent epidemiological study has shown that the use of non-specific diagnostic codes is common among dermatologists.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To study closely the use of the diagnostic codes L23.8 (‘allergic contact dermatitis [ACD] for other agents’) and L23.9 (‘ACD with unspecified cause’) by using single-centre data.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Patients/Materials/Methods</h3>\u0000 \u0000 <p>This retrospective study included all patients whose record contained at least one entry of either code, recorded at the Oulu University Hospital, Finland, between the Years 1999 and 2022.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The database search retrieved records of 472 patients with the L23.8 code, 264 patients with L23.9. Over the 20-year follow-up period, the use of L23.8 increased and that of L23.9 decreased. In most (85.1%) cases, the L23.8 code was used even though the more specified L23 code could have been chosen. In one-third of cases, L23.8 was used to cover ACD with multiple allergens that would otherwise be identified by their specific sub-codes. The L23.9 code was used most often prior to patch testing (69.1% cases).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This study revealed several imprecisions in the use of both codes. Our study highlights the importance of correct coding in clinical practice, as it emphasises the most common pitfalls.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":"92 4","pages":"273-276"},"PeriodicalIF":4.8,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cod.14744","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}