Contact Dermatitis最新文献

{"title":"Acute Localized Exanthematous Pustulosis-Like Dermatitis Induced by Nigella sativa Seed Oil.","authors":"Estelle Burle, Françoise Giordano","doi":"10.1111/cod.70276","DOIUrl":"https://doi.org/10.1111/cod.70276","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Allergic Contact Dermatitis Caused by Miconazole With Investigation of Cutaneous and Systemic Cross-Reactivity.","authors":"Florence Libon, Juliette Caron, Arjen Nikkels","doi":"10.1111/cod.70273","DOIUrl":"https://doi.org/10.1111/cod.70273","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics and Outcomes of Patients With Negative Patch Test Results and Systematic Literature Review.","authors":"Conan H Lee, Lauren W Hastings, Nicholas T Le, Olivia Keller, Christian Bryan De Guzman, Sydney Sullivan, Jasmin K Johl, Bruce Abbott, Peggy A Wu","doi":"10.1111/cod.70270","DOIUrl":"https://doi.org/10.1111/cod.70270","url":null,"abstract":"<p><strong>Background: </strong>Patients with negative patch test (NPT) results do not receive allergy avoidance counselling, and their experiences are important to understand.</p><p><strong>Objective: </strong>To describe the clinical presentation and outcomes associated with NPT results.</p><p><strong>Methods: </strong>Cross-sectional study analysing data from an IRB-approved REDCap registry. A systematic review was performed searching Ovid MEDLINE, Embase and Cochrane Library Databases.</p><p><strong>Results: </strong>161/1001 patients (769 female, 230 male) 16.1%, had NPTs. Mean age was 52.2 years (standard deviation 20.6). Median age, female predominance, race/ethnicity, duration of rash and number of patches placed was not significantly different between negative and positive patch test results. More NPT patients had leg involvement (p = 0.04) and prior biopsy (p = 0.002). 29.9% had a non-dermatitis diagnosis. The investigator and patient assessments were significantly improved post-patch testing. In a systematic review of 34 studies, 77261 patients, the NPT rate ranged between 16.7% and 83.1% and number of patches placed from 20 to 102. The most common areas of dermatitis were the hands.</p><p><strong>Conclusions: </strong>In our cohort and systematic review, a minority of patients have NPTs, with no major demographic differences. NPT patients have had prior biopsies, suggesting an unusual presentation. They were also commonly diagnosed with other forms of dermatitis, although 30% had a non-dermatitis diagnosis.</p>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149219949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sunscreen Intolerance in Frontal Fibrosing Alopecia Due to Clinically Relevant Benzyl Salicylate Sensitization Despite Negative Baseline and Sunscreen Patch Test Series.","authors":"Álvaro González-González, José Jaime Goday Buján, Jesús Del Pozo Losada","doi":"10.1111/cod.70271","DOIUrl":"https://doi.org/10.1111/cod.70271","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149191893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isothiazolinone Sensitization During School-Based Vocational Training: Occupational Hand Dermatitis in a Teenage Motorcycle Mechanic Trainee.","authors":"Paolo Antonio Danza, Giulia Ciccarese, Françoise Giordano, Giorgia Sbarra, Francesca Ambrogio, Thérèse Nocera, William Andrew Rosato, Giuseppe Demichele, Paolo Romita, Domenico Bonamonte, Caterina Foti","doi":"10.1111/cod.70272","DOIUrl":"https://doi.org/10.1111/cod.70272","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149191940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Generalized Nummular Eczema Linked to a Knee Prosthesis.","authors":"Ines Chebbi, Juliette Caron, Arjen Nikkels, William Kurth, Florence Libon","doi":"10.1111/cod.70266","DOIUrl":"https://doi.org/10.1111/cod.70266","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of 2-Cyanoethyl Dimethyldithiocarbamate in Another Rubber Glove Marketed as Accelerator-Free.","authors":"Andreas Hansen, Christoph Skudlik, Rachid Ngazi, Silke Werner, Cecilia Svedman, Linda Ljungberg Silic, Ola Bergendorff, Richard Brans","doi":"10.1111/cod.70269","DOIUrl":"https://doi.org/10.1111/cod.70269","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sodium Metabisulphite Contact Allergy: Think Wine and Food!","authors":"Thomas R. Brasher,&nbsp;Amanda Palmer,&nbsp;Rosemary L. Nixon","doi":"10.1111/cod.70224","DOIUrl":"10.1111/cod.70224","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Sodium metabisulphite (SMBS) is a known contact hapten in beverages, foodstuffs, hair dyes, topical and systemic medications, and cosmetics.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To investigate SMBS contact allergy in our tertiary referral patch testing clinics.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective audit was performed of 1367 patients patch tested to 1.0% SMBS in petrolatum between 1/1/2014 and 31/12/2023, and added to the Australian Baseline Series in 2020. Relevance was assessed by consultant dermatologists.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>87/1367 (6.4%) patients patch tested to SMBS had a positive reaction; 24/87 (27.6%) of these reactions were relevant. No cases were occupational. Eight (33.3%) cases presented with oral lichen planus (OLP) whilst four (16.7%) presented with allergic contact cheilitis (ACC). Overall, 19 (79.2%) patients had facial, oral or lip-related involvement. The most common exposure sources were alcoholic beverages (12 patients, 50%), mostly wine, and foodstuffs (10 patients, 41.7%), mostly dried fruits. Eight patients had more than one source of exposure. However, patients often reacted to multiple haptens, so other factors may have contributed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>SMBS contact allergy is not uncommon, but relevance can be difficult to ascertain. OLP, ACC, and facial rashes predominated. Wine and foodstuffs were the most important sources of exposure. SMBS should be included in baseline patch series.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":"95 5","pages":"461-474"},"PeriodicalIF":4.1,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148561126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tetrahydrofurfuryl Methacrylate and Isobornyl Acrylate: Possible New Sensitisers in Hearing Aid Ear Moulds","authors":"Norbertus A. Ipenburg,&nbsp;Anton C. de Groot,&nbsp;Thomas Rustemeyer","doi":"10.1111/cod.70228","DOIUrl":"10.1111/cod.70228","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Allergic contact dermatitis from hearing aid ear moulds is infrequently reported.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To identify cases of allergic contact dermatitis from hearing aid moulds in a cohort of patients investigated between 2022 and 2025 at Amsterdam University Medical Center.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Retrospective analysis of patients referred for investigation of suspected allergic reactions to ear moulds.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of 20 patients with suspected allergic reactions to ear moulds, 8 (40%) had positive patch tests to (meth)acrylates considered to be probably relevant. All eight reacted to tetrahydrofurfuryl methacrylate, of whom five had a positive reaction to this hapten only. The other three all co-reacted to isobornyl acrylate and 1,6-hexanediol diacrylate. None had positive patch tests to hydroxyethyl methacrylate.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>There are strong indications that tetrahydrofurfuryl methacrylate and isobornyl acrylate are relevant contact allergens present in hearing aid ear moulds. Hydroxyethyl methacrylate did not identify a single case of contact allergy to these materials.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":"95 5","pages":"492-497"},"PeriodicalIF":4.1,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cod.70228","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A New Case of Severe Allergic Contact Dermatitis Following a Recreational Exposure to Epoxy Resin","authors":"Eva Ibeka,&nbsp;Olivier Dereure,&nbsp;Nadia Raison-Peyron","doi":"10.1111/cod.70229","DOIUrl":"10.1111/cod.70229","url":null,"abstract":"&lt;p&gt;The increasing popularity of creative leisure activities has resulted in the emergence of non-occupational allergic contact dermatitis (ACD) to epoxy resins, and we report here a new case.&lt;/p&gt;&lt;p&gt;A 41-year-old female physiotherapist with a history of atopic dermatitis and ACD to fragrances previously confirmed by positive patch tests presented with a severe facial dermatitis following the first use of an epoxy resin system purchased on line for home jewellery making without using personal protective equipment. The product label of the epoxy resin (bottle A) mentioned the presence of bisphenol A diglycidyl ether (CAS 25068-38-6) and alkyl (C12-C14) diglycidyl ether (CAS 68609-97-2). The hardener (bottle B) contained benzyl alcohol (CAS 100-51-6), amines such as polypropylene glycol diamine (CAS 9046-10-0), isophorone diamine (CAS 2855-13-2) and 1,3-cyclohexanedimethanamine (CAS 2579-20-6).&lt;/p&gt;&lt;p&gt;Within 6 h of exposure, the patient developed an itchy erythematous, edematous eruption involving the face, neck and upper chest (Figure 1). Owing to the aspect and location of the rash, airborne ACD was primarily suspected. Treatment with dexchlorpheniramine and oral corticosteroids led to resolution of symptoms in several days with residual xerosis.&lt;/p&gt;&lt;p&gt;Several months earlier, she had bought in a discount store acrylic resins in powder and liquid form designed to be mixed together for creative hobby activities and used it with no problem whatsoever. She didn't wear artificial nails.&lt;/p&gt;&lt;p&gt;Patch testing was performed with the European baseline series, epoxy series, acrylates series and fragrance series (Chemotechnique Diagnostics, Vellinge, Sweden) except the 1,4-butanediol diglycidyl ether (1,4-BDDE), which comes from Allergeaze (SmartPractice Canada). The epoxy resin and its hardener were tested using 0.1% pet semi-open tests. Readings were performed on day (D)2 and D3 according to ESCD guidelines, with a late reading at D7 with photos if necessary [&lt;span&gt;1&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Epoxy resin systems are associations of epoxy resins, curing agents (hardeners) and modifiers [&lt;span&gt;2&lt;/span&gt;]. Most epoxy resin systems contain epoxy resins based on diglycidyl ether of bisphenol A (epoxy resin, bisphenol A) and/or based on diglycidyl ether of bisphenol F (epoxy resin, bisphenol F) [&lt;span&gt;2&lt;/span&gt;]. These chemicals are well-known sensitizers, and patients sensitized to diglycidyl ether of bisphenol F (DGEBF)-based resins often equally react to diglycidyl ether of bisphenol A (DGEBA)-based ones [&lt;span&gt;3, 4&lt;/span&gt;]. DGEBA-R is the most common sensitizer in epoxy resin systems [&lt;span&gt;5&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Our patient was also sensitized to 1,4-BDDE which is an epoxy reactive diluent. The bottle A contained alkyl (C12-C14) diglycidyl ether which hypothetically cross-reacts with 1,4-BDDE.&lt;/p&gt;&lt;p&gt;The positive reactions to the epoxy acrylates bis-GMA and to bis-EMA may be explained by possible cross-allergy between DGEBA and epoxy acrylates [&lt;span&gt;6&lt;/span&gt;]. The rapid allergic","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":"95 5","pages":"511-513"},"PeriodicalIF":4.1,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cod.70229","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148668632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}