Olivier Aerts, Thomas Rustemeyer, Anna Belloni-Fortina, Sonia Badulici, Heinrich Dickel, Jose Luis Garcia Abujeta, Ana Maria Giménez-Arnau, Margarida Gonçalo, Catherine R Holden, Marléne Isaksson, Faheem Latheef, Suzana Ljubojevic Hadzavdic, Vera Mahler, Esen Özkaya, Gyorgyi Ponyai, Nives Pustišek, Marie-Louise Schuttelaar, Jakob Schwensen, Radoslaw Spiewak, Luca Stingeni, Cecilia Svedman, Wolfgang Uter, Jonathan M L White, Mark Wilkinson, Anne-Birgitte Simonsen, Jeanne Duus Johansen
{"title":"Variability in Paediatric Patch Test Practices Across Europe: A Survey From the European Baseline Series (EBS) Working Party on Behalf of the European Society of Contact Dermatitis (ESCD).","authors":"Olivier Aerts, Thomas Rustemeyer, Anna Belloni-Fortina, Sonia Badulici, Heinrich Dickel, Jose Luis Garcia Abujeta, Ana Maria Giménez-Arnau, Margarida Gonçalo, Catherine R Holden, Marléne Isaksson, Faheem Latheef, Suzana Ljubojevic Hadzavdic, Vera Mahler, Esen Özkaya, Gyorgyi Ponyai, Nives Pustišek, Marie-Louise Schuttelaar, Jakob Schwensen, Radoslaw Spiewak, Luca Stingeni, Cecilia Svedman, Wolfgang Uter, Jonathan M L White, Mark Wilkinson, Anne-Birgitte Simonsen, Jeanne Duus Johansen","doi":"10.1111/cod.14824","DOIUrl":"https://doi.org/10.1111/cod.14824","url":null,"abstract":"<p><strong>Background: </strong>Allergic contact dermatitis (ACD) is an increasingly recognised condition in children and adolescents. However, there is limited knowledge about the different paediatric patch test procedures in European patch test clinics.</p><p><strong>Objectives: </strong>To map current European paediatric patch test practices, and to relate these to the existing literature, with the aim of guiding the development of a future paediatric patch test guideline, and a corresponding paediatric European baseline series (pEBS).</p><p><strong>Materials and methods: </strong>In the course of late 2023/early 2024, a standardised paediatric patch test e-mail questionnaire was developed, distributed, and discussed among members of the European Baseline Series (EBS) Working Party of the European Society of Contact Dermatitis (ESCD).</p><p><strong>Results: </strong>Areas of agreement and discussion were identified regarding patch testing in children of different ages, with and without atopic dermatitis: (contra)indications, choice of allergens and patch test chambers, peculiarities regarding the application and fixation of tests, occlusion and reading times.</p><p><strong>Conclusion: </strong>Although variability exists in paediatric patch test practices across Europe, there is broad agreement on common procedures, and only a few areas of debate; these findings may be used to inform the development of a future paediatric patch test guideline and pEBS.</p>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brent J Doolan, Louise Cunningham, Ian R White, Elizabeth Powell, Ying X Teo
{"title":"Co-Sensitization After Single-Dose Antibiotic Exposure During Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS): The Role of Repeat Drug Patch Testing.","authors":"Brent J Doolan, Louise Cunningham, Ian R White, Elizabeth Powell, Ying X Teo","doi":"10.1111/cod.14825","DOIUrl":"https://doi.org/10.1111/cod.14825","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Occupational Allergic Contact Dermatitis to Formaldehyde Released by Work Clothes.","authors":"Tina Lejding, Anna Kiuru, Ola Bergendorff","doi":"10.1111/cod.14827","DOIUrl":"https://doi.org/10.1111/cod.14827","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angéline Charansol, V Bourdenet, Anatole Hanniet, Fabien Pelletier, François Aubin, Florence Castelain
{"title":"Infrared Radiation-Induced Urticaria: A Case Report.","authors":"Angéline Charansol, V Bourdenet, Anatole Hanniet, Fabien Pelletier, François Aubin, Florence Castelain","doi":"10.1111/cod.14826","DOIUrl":"https://doi.org/10.1111/cod.14826","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Theres Heichel, Jan F Kersten, Antje Braumann, Kathrin Krambeck, Sonja Bonness, Claudia Schröder-Kraft, Robert Ofenloch, Elke Weisshaar, Kerstin Strom, Christoph Skudlik, Flora Sonsmann, Annika Wilke, Albert Nienhaus, Swen Malte John, Richard Brans
{"title":"Evaluation of Glove Liners Made of Semipermeable and Textile Materials in Patients With Hand Dermatoses: Results of a Multicenter Intervention Study (ProTection II).","authors":"Theres Heichel, Jan F Kersten, Antje Braumann, Kathrin Krambeck, Sonja Bonness, Claudia Schröder-Kraft, Robert Ofenloch, Elke Weisshaar, Kerstin Strom, Christoph Skudlik, Flora Sonsmann, Annika Wilke, Albert Nienhaus, Swen Malte John, Richard Brans","doi":"10.1111/cod.14822","DOIUrl":"https://doi.org/10.1111/cod.14822","url":null,"abstract":"<p><strong>Background: </strong>Glove liners (GLs) are worn under impermeable gloves to prevent occlusion effects.</p><p><strong>Objectives: </strong>To evaluate the acceptance and tolerability of cotton gloves (COT) and semipermeable Sympatex gloves (SYM) as GLs in patients with hand dermatoses.</p><p><strong>Methods: </strong>In a prospective multicenter study, 210 patients with work-related hand dermatoses were invited to wear either COT or SYM as GLs for 4 weeks underneath occlusive protective gloves during their regular work tasks. Acceptance of GL and health-related quality of life (HRQoL) were assessed by questionnaires and the disease severity by the Osnabrueck Hand Eczema Severity Index.</p><p><strong>Results: </strong>A total of 178 data sets were available (SYM: n = 89/103, 86.4%; COT: n = 89/107, 83.2%). Both GLs did not impair work performance and were applicable in various work activities. SYM received better ratings regarding climate conditions, mobility and tactility. COT showed superiority in fit, donning and doffing. No substantial intergroup differences regarding disease severity and HRQoL were observed.</p><p><strong>Conclusions: </strong>SYM and COT were well tolerated and accepted, suggesting that SYM is a reasonable alternative for COT as GL in patients with hand dermatoses. The choice of material of GLs may depend on occupation-specific requirements for the performed tasks, individual needs and preferences.</p>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Hilewitz, Akiva Trattner, Asher Hackett, Adi Raviv, Yehonatan Noyman, Stav Endelman, Dan Slodownik, Danny Daniely, Rivka Friedland, Daniel Mimouni, Igor Snast
{"title":"Epidemiology of Sensitivity to Nickel, Cobalt and Chromium in Israel: A Retrospective Cohort Study.","authors":"Daniel Hilewitz, Akiva Trattner, Asher Hackett, Adi Raviv, Yehonatan Noyman, Stav Endelman, Dan Slodownik, Danny Daniely, Rivka Friedland, Daniel Mimouni, Igor Snast","doi":"10.1111/cod.14820","DOIUrl":"https://doi.org/10.1111/cod.14820","url":null,"abstract":"<p><strong>Background: </strong>Nickel, cobalt and chromium are three common allergens included in the European baseline series (EBS). It was shown that sensitivity to nickel and cobalt is more frequent among young women, most commonly due to contact with inexpensive jewellery, while sensitivity to chromium is more common among older men. Israel is located in West Asia and hosts the largest Jewish population in the world. There is limited data regarding the epidemiology of these metals in Israel or in the Mediterranean region.</p><p><strong>Objective: </strong>To investigate the epidemiology of sensitivity to nickel, cobalt and chromium in the EBS in a single center in Israel between 2009 and 2023.</p><p><strong>Methods: </strong>Retrospective cohort study that included all patients who underwent patch testing with the EBS in a tertiary center in Israel between 2009 and 2023.</p><p><strong>Results: </strong>Of 5234 consecutive patients (1679 males [32.1%]) 2158 (41%) were sensitive to nickel, 541 (10.3%) to cobalt and 383 (7.3%) to chromium. During the study period, nickel sensitivity was stable and was associated with female sex and age 18-40 years. Among both sexes, cobalt sensitivity decreased significantly from 11.7% in 2009-2011 to 7.9% in 2020-2023 and was associated with female sex and age < 18 years. Chromium sensitivity decreased significantly from 11.1% in 2009-2011 to 5% in 2020-2023 and was associated with male sex and older age (> 60 years). Among both sexes, cobalt strongly co-reacted with nickel (OR = 1.69, 95% CI 1.38-2.06, p < 0.001) and chromium (OR = 3.57, 95% CI 2.67-4.55, p < 0.001). Nickel-cobalt co-sensitization was significantly more common among patients with strong (++) or very strong (+++) nickel sensitivity compared to patients with weak (+) sensitivity. Males, but not females, with nickel sensitivity positively co-reacted with chromium. Among patients with nickel sensitivity, the strong (++) or very strong (+++) reaction (36.3%) was significantly more common compared to patients with cobalt or chromium sensitivity.</p><p><strong>Conclusion: </strong>In this retrospective Israeli study, the prevalence of sensitivity to nickel was stable but much higher compared to European and North American studies, highlighting the necessity for multicenter and general population studies and possibly a legislation regarding nickel restriction of items with prolonged contact with the skin. Cobalt and chromium sensitivities decreased and were in line with previous studies.</p>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marc Rocholl, Richard Brans, Annika Wilke, Julia Meyer, Swen Malte John, Michaela Ludewig
{"title":"Emotional Burden of Patients With Work-Related Hand Eczema: Results of an Exploratory Study in a Tertiary Individual Prevention Setting in Germany.","authors":"Marc Rocholl, Richard Brans, Annika Wilke, Julia Meyer, Swen Malte John, Michaela Ludewig","doi":"10.1111/cod.14819","DOIUrl":"https://doi.org/10.1111/cod.14819","url":null,"abstract":"<p><strong>Background: </strong>Work-related hand eczema (WRHE) is a prevalent skin condition associated with reduced health-related quality of life (HRQoL), sleep disturbances or depression. While prior studies primarily explored emotional effects as part of HRQoL, emotions have been less studied separately.</p><p><strong>Objectives: </strong>To evaluate the psychometric properties of the 'Atopic Eczema Score of Emotional Consequences' (AESEC) in patients with WRHE and to investigate the emotional impact of WRHE.</p><p><strong>Methods: </strong>Self-reported sociodemographic data as well as self-reported and clinically assessed disease severity of 223 patients (55.6% female; mean age: 48.1 ± 12.0 years) taking part in a tertiary prevention program for WRHE were included in the analysis. The factor structure was checked using an exploratory factor analysis. The emotional burden was determined using the AESEC.</p><p><strong>Results: </strong>The three underlying facets of emotional consequences, as previously described in the validation study of the AESEC, could not be replicated in patients with WRHE. Positive emotions were emphasised by items such as optimism, balance and self-confidence. Emotional burden was most evident in worries about life, sadness, lack of control, feelings of constraint and disturbance by itch.</p><p><strong>Conclusions: </strong>Patients with WRHE face a significant emotional burden indicating a great need for psychological support. Further studies on the psychometric properties of the AESEC in patients with WRHE are warranted.</p>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Pesqué, Emilio Berná-Rico, Gabija Rudzikaitė, Ramon M Pujol, Fernando Gallardo, Ana M Giménez-Arnau
{"title":"Photo-Aggravated Allergic Contact Dermatitis due to Hydroxyacetophenone Present in a Sunscreen: A Case Report.","authors":"David Pesqué, Emilio Berná-Rico, Gabija Rudzikaitė, Ramon M Pujol, Fernando Gallardo, Ana M Giménez-Arnau","doi":"10.1111/cod.14823","DOIUrl":"https://doi.org/10.1111/cod.14823","url":null,"abstract":"","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trends in Contact Allergy to Preservatives From 2014 to 2023: Benzisothiazolinone on the Rise.","authors":"Rebekka Søgaard, Christoffer Kursawe Larsen, Jeanne Duus Johansen, Jakob Ferløv Baselius Schwensen","doi":"10.1111/cod.14818","DOIUrl":"https://doi.org/10.1111/cod.14818","url":null,"abstract":"<p><strong>Background: </strong>Skin sensitising preservatives are commonly used in consumer and industrial products. The widespread use of preservatives has led to recurrent epidemics of contact allergy.</p><p><strong>Objectives: </strong>To investigate temporal trends of contact allergy to preservatives from 2014 to 2023.</p><p><strong>Materials and methods: </strong>Patients consecutively patch tested with preservatives from the European baseline series and the supplementary baseline series at Gentofte hospital from 2014 to 2023 were included.</p><p><strong>Results: </strong>The study population included 6435 patients. Contact allergy to benzisothiazolinone (BIT) increased significantly from ≤ 0.3% in 2014 to 5.0% in 2023. Painters and machine operators, and assemblers were most often sensitised to BIT, and detergents and paints were the most common exposures to BIT. Contact allergy to methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) decreased significantly from 3.3% in 2014 to 2.2% in 2023. Likewise, contact allergy to MI declined significantly from 3.9% in 2014 to 2.5% in 2023. Stable trends were found for the overall prevalence of contact allergy to preservatives from 9.0% in 2014 to 10.2% in 2023.</p><p><strong>Conclusions: </strong>Regulatory restrictions on the use of MI and MCI/MI in cosmetic products have led to a decrease in contact allergy. However, the rise in contact allergy to BIT underscores the need for ongoing monitoring and preventive measures.</p>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}