Colorectal Disease最新文献

{"title":"EXPRESSION OF CONCERN: Laparoscopic Ventral Mesh Rectopexy in Male Patients with Internal or External Rectal Prolapse","authors":"","doi":"10.1111/codi.70069","DOIUrl":"https://doi.org/10.1111/codi.70069","url":null,"abstract":"<p><b>EXPRESSION OF CONCERN:</b> A.E. Owais, H. Sumrien, K. Mabey, K. McCarthy, G.L. Greenslade, and A.R. Dixon, “Laparoscopic Ventral Mesh Rectopexy in Male Patients with Internal or External Rectal Prolapse,” <i>Colorectal Disease</i> 16, no. 12 (2014): 995–1000, https://doi.org/10.1111/codi.12763.</p><p>This Expression of Concern is for the above article, published online on 1 September 2014 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editors-in-Chief, Sue Clark and Neil Smart; The Association of Coloproctology of Great Britain and Ireland; and John Wiley &amp; Sons Ltd. The Expression of Concern has been agreed due to concerns raised regarding the legitimacy of the data reported and allegations of a lack of informed consent from patients who underwent the surgical procedure reported within. The investigation into these concerns is ongoing. Therefore, the journal has decided to issue an Expression of Concern to inform and alert the readers.</p>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/codi.70069","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EXPRESSION OF CONCERN: Consensus on Ventral Rectopexy: Report of a Panel of Experts","authors":"","doi":"10.1111/codi.70071","DOIUrl":"https://doi.org/10.1111/codi.70071","url":null,"abstract":"<p><b>EXPRESSION OF CONCERN</b>: M.A. Mercer-Jones, A. D‘Hoore, A.R. Dixon, P. Lehur, I. Lindsey, A. Mellgren, and A.R.L. Stevenson, “Consensus on Ventral Rectopexy: Report of a Panel of Experts,” <i>Colorectal Disease</i> 16, no. 2 (2014): 82–88, https://doi.org/10.1111/codi.12415.</p><p>This Expression of Concern is for the above article, published online on 6 September 2013 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editors-in-Chief, Sue Clark and Neil Smart; The Association of Coloproctology of Great Britain and Ireland; and John Wiley &amp; Sons Ltd. The Expression of Concern has been agreed due to concerns raised regarding the surgical and research practices of one of the coauthors, Anthony Dixon, and two of Dr. Dixon‘s cited articles (Owais et al., 2014 [https://doi.org/10.1111/codi.12763]; Randall et al. 2014 [https://doi.org/10.1111/codi.12741]) that are under investigation by the publisher. The investigation into these concerns is ongoing. Therefore, the journal has decided to issue an Expression of Concern to inform and alert the readers.</p>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/codi.70071","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EXPRESSION OF CONCERN: Laparoscopic Ventral Mesh Rectopexy in the Management of Solitary Rectal Ulcer Syndrome: A Cause for Optimism?","authors":"","doi":"10.1111/codi.70064","DOIUrl":"https://doi.org/10.1111/codi.70064","url":null,"abstract":"<p><b>EXPRESSION OF CONCERN</b>: A.H. Badrek-Amoudi, T. Roe, K. Mabey, H. Carter, A. Mills, and A.R. Dixon, “Laparoscopic Ventral Mesh Rectopexy in the Management of Solitary Rectal Ulcer Syndrome: A Cause for Optimism?,” <i>Colorectal Disease</i> 15, no. 5 (2013): 575–581, https://doi.org/10.1111/codi.12077.</p><p>This Expression of Concern is for the above article, published online on 29 October 2012 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editors-in-Chief, Sue Clark and Neil Smart; The Association of Coloproctology of Great Britain and Ireland; and John Wiley &amp; Sons Ltd. The Expression of Concern has been agreed due to concerns raised regarding the legitimacy of the data reported and allegations of a lack of informed consent from patients who underwent the surgical procedure reported within. The investigation into these concerns is ongoing. Therefore, the journal has decided to issue an Expression of Concern to inform and alert the readers.</p>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/codi.70064","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EXPRESSION OF CONCERN: Use of the Ethicon EndoSurgery Anoscope Retractor for Anorectal Procedures Other than Stapled Haemorrhoidectomy","authors":"","doi":"10.1111/codi.70063","DOIUrl":"https://doi.org/10.1111/codi.70063","url":null,"abstract":"<p><b>EXPRESSION OF CONCERN:</b> B.N. Chaudhary, F. Alam, and A.R. Dixon, “Use of the Ethicon EndoSurgery Anoscope Retractor for Anorectal Procedures Other than Stapled Haemorrhoidectomy,” <i>Colorectal Disease</i>. 14, no. 5 (2012): 644–645. https://doi.org/10.1111/j.1463-1318.2012.02951.x.</p><p>This Expression of Concern is for the above correspondence, published online on 19 January 2012 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editors-in-Chief, Sue Clark and Neil Smart; The Association of Coloproctology of Great Britain and Ireland; and John Wiley &amp; Sons Ltd. The Expression of Concern has been agreed due to concerns raised regarding the surgical and research practices of the coauthor Anthony Dixon. The investigation into these concerns is ongoing. Therefore, the journal has decided to issue an Expression of Concern to inform and alert the readers.</p>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/codi.70063","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Small-bites versus large-bites closure of midline laparotomies: A systematic review and meta-analysis","authors":"Stefan Morarasu,&nbsp;Sorinel Lunca,&nbsp;Luke O'Brien,&nbsp;Paul Lynch,&nbsp;Ana Maria Musina,&nbsp;Cristian Ene Roata,&nbsp;Raluca Zaharia,&nbsp;Wee Liam Ong,&nbsp;Gabriel-Mihail Dimofte,&nbsp;Cillian Clancy","doi":"10.1111/codi.70073","DOIUrl":"https://doi.org/10.1111/codi.70073","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Surgical site infection (SSI) and incisional hernia (IH) are common complications following midline laparotomy. The small-bites technique for closing a midline laparotomy has been suggested to improve SSI and IH rates compared with the classic mass closure. The aim of this work was to perform a systematic review, meta-analysis and fragility assessment of existing evidence comparing small-bites and conventional closure.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>The study was registered with PROSPERO. A systematic search of PubMed and EMBASE databases was performed for all comparative studies examining small-bites versus conventional closure for midline laparotomy. The fragility index for randomized controlled trials (RCTs) was assessed and the number of outcomes required to render results insignificant using the Fisher exact test was calculated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Seven studies were included, with a total of 3807 patients. Small bites was performed in 1768 and large bites in 2039. Follow-up ranged from 12 to 52 months. On meta-analysis of all studies, small bites is associated with a lower risk of IH (<i>p</i> &lt; 0.00001), SSI (<i>p</i> = 0.0002) and wound dehiscence (<i>p</i> = 0.02). On meta-analysis of RCTs there is a lower risk of IH (<i>p</i> = 0.01) but no difference in SSI (<i>p</i> = 0.06) or wound dehiscence (<i>p</i> = 0.73). Fragility is evident among RCTs reporting differences in IH rates.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>There is evidence to suggest that small-bites closure provides a decreased likelihood of IH over varying follow-up in RCTs but significant fragility exists among studies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/codi.70073","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Total neoadjuvant therapy in early-onset rectal cancer: A multicentre prospective cohort study","authors":"Sergei Bedrikovetski,&nbsp;Ishraq Murshed,&nbsp;Tracy Fitzsimmons,&nbsp;Luke Traeger,&nbsp;Timothy J. Price,&nbsp;Michael Penniment,&nbsp;Sudarshan Selva-Nayagam,&nbsp;Ryash Vather,&nbsp;Tarik Sammour","doi":"10.1111/codi.70059","DOIUrl":"https://doi.org/10.1111/codi.70059","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The incidence of early-onset (age &lt;50 years) rectal cancer (EORC) is rising globally, often presenting at an advanced stage. Total neoadjuvant therapy (TNT) is increasingly utilised in the management of advanced rectal cancers due to improved response and survival rates. However, it remains unclear whether EORC in an unscreened population responds similarly to TNT compared to average or late-onset (age ≥50 years) rectal cancer (AORC).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>This study included consecutive patients treated with curative intent with TNT for rectal cancer at three South Australian hospitals between 2019 and 2024. Patients were divided into EORC and AORC cohorts. The primary outcome was overall complete response (oCR) rate, defined as the proportion of patients who achieved a clinical complete response (cCR) and/or pathological complete response (pCR). Secondary outcomes included compliance and treatment-related toxicity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of 202 eligible patients, 48 (23.8%) were in the EORC cohort and 154 (76.2%) in the AORC cohort. No significant difference in oCR rate was observed between EORC and AORC patients (43.8% vs. 37.9%, <i>P</i> = 0.470). cCR, pCR and complete M1 response rates were also similar between the two groups. EORC patients experienced significantly less Grade 3–4 chemotherapy-induced toxicity compared to AORC patients (2.1% vs. 25.3%, <i>P</i> &lt; 0.001), but reported higher rates of patient-reported Grade 3–4 radiotherapy-induced toxicity than AORC patients (31.3% vs. 12.3%, <i>P</i> = 0.004).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>EORC patients exhibit comparable overall tumour response rates to AORC patients treated with TNT. However, toxicity profiles differ, with EORC patients experiencing less chemotherapy-induced toxicity but more patient-reported radiation-induced toxicity.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/codi.70059","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alcohol consumption and risk of early onset colorectal cancer: A systematic review and meta-analysis","authors":"Siyu Huang,&nbsp;Lulin Yu,&nbsp;Fengchun Xiong,&nbsp;Bo Zhang,&nbsp;Shanming Ruan","doi":"10.1111/codi.70046","DOIUrl":"https://doi.org/10.1111/codi.70046","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The existing evidence has shown a positive association between alcohol consumption and an increased risk of colorectal cancer (CRC). However, the evidence is primarily based on studies of CRC in all ages, and the role of alcohol in early onset colorectal cancer (EOCRC) remains to be determined. The aim of this study was to investigate an association between the increasing incidence of EOCRC and alcohol consumption.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>We systematically searched PubMed, EMBASE, Cochrane and Web of Science up to June 2024 for studies that evaluated the association of alcohol intake with EOCRC risk and report specific results (e.g. relative risk, OR or hazard ratio and corresponding 95% CI). Based on the varying designs of the included studies, the corresponding effect values were extracted and categorized into high alcohol consumption and low alcohol consumption groups; a random-effects model was adopted to estimate the pooled effect sizes for analysis. Furthermore, subgroup analyses and publication bias assessments were conducted.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Three cohort studies and eight case–control studies were eligible and included. The results were pooled in meta-analyses, which yielded a heightened risk of EOCRC for increased alcohol intake (OR = 1.56, 95% CI 1.28–1.89, <i>I</i>² = 89.3%). In the subgroup analysis, no significant differences were found in the association between alcohol consumption and the risk of developing EOCRC across gender, location or tumour site. The results of sensitivity analysis and publication bias indicated that the conclusion was robust.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This meta-analysis provides possible evidence for an association between alcohol consumption and risk of EOCRC. More research is needed in the future to confirm these findings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143690164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic nerve-sparing ultralow anterior resection with transanal transection and single-stapled anastomosis—A video vignette","authors":"Carlos Pastor,&nbsp;María Sánchez-Rodríguez,&nbsp;Andrea Craus,&nbsp;Nicolás Pedano Rodríguez,&nbsp;Patricia Tejedor","doi":"10.1111/codi.70072","DOIUrl":"https://doi.org/10.1111/codi.70072","url":null,"abstract":"","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survivorship issues in long-term survivors of locally recurrent rectal cancer: A qualitative study","authors":"Niamh McKigney,&nbsp;Sophia Waldenstedt,&nbsp;Elisabeth Gonzalez,&nbsp;Jan M. van Rees,&nbsp;Henriette Vind Thaysen,&nbsp;Eva Angenete,&nbsp;Galina Velikova,&nbsp;Julia M. Brown,&nbsp;Deena P. Harji,&nbsp;LRRC-QoL Collaborators","doi":"10.1111/codi.70051","DOIUrl":"10.1111/codi.70051","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>There are increasing numbers of long-term survivors following curative treatment for locally recurrent rectal cancer (LRRC); however, their experiences remain relatively underreported. The aim of this qualitative study was to identify the long-term survivorship issues relevant to these patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Adults who remained disease free &gt;3 years following treatment for LRRC were invited to participate in an international multicentre study. Semistructured qualitative interviews were conducted either in person, via telephone or via Microsoft Teams and were analysed using a framework method of thematic analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 26 participants were recruited from 11 sites in seven countries. Sixteen (61.5%) participants were male, the median age was 70.5 (33.0–85.0) years, participants were a median of 5.0 (3.0–17.0) years posttreatment, most had undergone surgery for LRRC (<i>n</i> = 24, 92.3%), two participants received neoadjuvant chemo/radiation for LRRC with a complete response. Eight major survivorship themes were identified: (1) experience of long-term follow-up care, (2) unmet needs and areas for improvement, (3) long-term physical effects of cancer and treatment, (4) living with a stoma, urostomy or other urinary device, (5) long-term psychological impact, (6) impact on sexual function and intimate relationships, (7) impact on daily life and (8) feelings surrounding life now, adapting and the future.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Participants experienced a wide range of long-term survivorship issues, reflecting the complexity of both LRRC and its treatment. Despite this, most had adapted well. Further work regarding survivorship care in LRRC is required to address the unmet needs and issues highlighted in this study, such as support regarding sexual function.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal quality of life assessment after laparoscopic colorectal cancer surgery using the Gastrointestinal Quality of Life Index questionnaire: A multicentre prospective study","authors":"Tae-Gyun Lee,&nbsp;Seung-Bum Ryoo,&nbsp;Heung-Kwon Oh,&nbsp;Yong Beom Cho,&nbsp;Chang Hyun Kim,&nbsp;Ju Hyun Lee,&nbsp;Hong-Min Ahn,&nbsp;Hye-Rim Shin,&nbsp;Mi Jeong Choi,&nbsp;Min Hyeong Jo,&nbsp;Duck-Woo Kim,&nbsp;Sung-Bum Kang","doi":"10.1111/codi.70060","DOIUrl":"10.1111/codi.70060","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The aim of this study was to validate the Gastrointestinal Quality of Life Index (GIQLI) and assess its effectiveness in measuring changes in postoperative quality of life (QOL) after laparoscopic colorectal cancer surgery, including factors affecting early QOL impairment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>This multicentre prospective study enrolled patients who underwent laparoscopic colorectal cancer surgery between November 2021 and February 2023. Participants completed the GIQLI and European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire for Colorectal Cancer (EORTC QLQ-CR29) questionnaires preoperatively and at 1 and 3 weeks, 6 months and 1 year postoperatively. We evaluated GIQLI reliability, identified risk factors associated with early postoperative QOL impairment and assessed longitudinal changes in QOL to determine the timing of postoperative recovery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The GIQLI showed high reliability, with a preoperative intraclass correlation coefficient of 0.930 (95% CI 0.899–0.951) and Cronbach alpha values &gt;0.9 at all time points. The mean global GIQLI score decreased from 106.2 ± 14.7 preoperatively to 92.7 ± 15.2 at 1 week postoperatively (<i>p</i> &lt; 0.001), recovered to 104.6 ± 13.8 at 6 months postoperatively (versus preoperatively, <i>p</i> &gt; 0.99) and increased to 113.4 ± 13.3 at 1 year postoperatively (versus preoperatively, <i>p</i> &lt; 0.001). Early T-stage (T1–2; OR 2.82, 95% CI 1.25–6.40, <i>p</i> = 0.013) and intra-abdominal drain use (OR 3.95, 95% CI 1.09–14.28, <i>p</i> = 0.036) were significant risk factors for substantial impairment of QOL at 1 week postoperatively. The predicted recovery period to 95% of preoperative QOL was 6.4 weeks (95% CI 6.00–8.30 weeks).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The GIQLI reliably assessed longitudinal changes in QOL after laparoscopic colorectal cancer surgery and demonstrated QOL recovery within 2 months postoperatively, providing guidance for patient counselling and optimizing postoperative care.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}