Colorectal Disease最新文献

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Early detection and immediate repair of iatrogenic ureteral injury in laparoscopic anterior resection for recurrent rectal cancer—A video vignette 腹腔镜前切除术治疗复发性直肠癌医源性输尿管损伤的早期发现和立即修复——一段视频
IF 2.9 3区 医学
Colorectal Disease Pub Date : 2025-04-07 DOI: 10.1111/codi.70096
Carlo Alberto Manzo, Caterina Baldi, Leonardo Lorusso, Ai Ling Romanò, Gianluca Matteo Sampietro
{"title":"Early detection and immediate repair of iatrogenic ureteral injury in laparoscopic anterior resection for recurrent rectal cancer—A video vignette","authors":"Carlo Alberto Manzo, Caterina Baldi, Leonardo Lorusso, Ai Ling Romanò, Gianluca Matteo Sampietro","doi":"10.1111/codi.70096","DOIUrl":"https://doi.org/10.1111/codi.70096","url":null,"abstract":"","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143793414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oncological and functional outcomes after sacrectomy for colorectal cancer: A systematic review 结直肠癌骶骨切除术后的肿瘤和功能结果:一项系统综述
IF 2.9 3区 医学
Colorectal Disease Pub Date : 2025-04-04 DOI: 10.1111/codi.70083
Nathalie Braeckman, Eva Kerckhove, Andreas Denys, Gwen Sys, Gabriëlle H. van Ramshorst
{"title":"Oncological and functional outcomes after sacrectomy for colorectal cancer: A systematic review","authors":"Nathalie Braeckman,&nbsp;Eva Kerckhove,&nbsp;Andreas Denys,&nbsp;Gwen Sys,&nbsp;Gabriëlle H. van Ramshorst","doi":"10.1111/codi.70083","DOIUrl":"https://doi.org/10.1111/codi.70083","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Worldwide, of all cancers, colorectal cancer has the fourth highest rate of mortality. Curative treatment for locally advanced or recurrent rectal cancer can require extended resections with sacrectomy, but this sugery can have major consequences for patients. The aim of this study was to investigate the oncological and functional outcomes after sacrectomy in patients with colorectal cancer.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>The protocol was registered in (PROSPERO), the international prospective register of systematic reviews. PubMed, Embase, The Cochrane Library, Scopus and Google Scholar were searched using a predetermined search strategy. Article selection, quality of evidence [Grading of Recommendation, Assessment, Development and Evaluation (GRADE)] and risk of bias [The Risk Of Bias In Non-randomized Studies—of Interventions (ROBINS-I)] were assessed by two independent reviewers. Studies reporting on sacrectomy for colorectal cancer were included. Oncological and functional outcomes after sacrectomy for colorectal cancer were the primary outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Forty-six articles with 1687 patients (1115 men; 506 women) were included. Median follow-up was 31.4 months. Mean 30-day mortality was 1.1%. After R0 resection, overall survival was achieved in 86.2%, 68.0% and 42.1% patients, and disease-free survival was achieved in 75.0%, 51.0% and 43.0% patients, respectively, after 1, 3 and 5 years. Survival rates were lower after R1 or R2 resection. Most patients reported elimination of or significantly reduced pain after surgery, and 82.2% were able to walk independently, without the use of assistive devices. More patients were dependent on walking-assist devices after high sacrectomy than after low sacrectomy. The most commonly reported bowel dysfunctions were bowel obstruction (22.3%) and fistula (4.6%). Bladder dysfunction was mainly reported as incontinence (8.3%) and neurogenic bladder (23.3%). No study included quality of life as an outcome.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The mortality was limited, and the morbidity rates were in concordance with published literature. The results suggest that R0 resection has higher survival rates than R1/R2 resections. Both short- and long-term functional outcomes could have major impact on a patient's quality of life. Heterogeneity was high, and neither comparative analyses nor meta-analysis could be performed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robotic excision of a rare retrorectal cyst: Demonstration of operative strategy—A video vignette 机器人切除一个罕见的直肠后囊肿:手术策略的演示-视频片段
IF 2.9 3区 医学
Colorectal Disease Pub Date : 2025-04-02 DOI: 10.1111/codi.70080
Mahmood Al-Dhaheri, Ali Toffaha, Ibrahim Amer, Mahwish Khawar, Mohamed AbuNada, Amjad Parvaiz
{"title":"Robotic excision of a rare retrorectal cyst: Demonstration of operative strategy—A video vignette","authors":"Mahmood Al-Dhaheri,&nbsp;Ali Toffaha,&nbsp;Ibrahim Amer,&nbsp;Mahwish Khawar,&nbsp;Mohamed AbuNada,&nbsp;Amjad Parvaiz","doi":"10.1111/codi.70080","DOIUrl":"https://doi.org/10.1111/codi.70080","url":null,"abstract":"","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robotic right hemicolectomy with D3 lymphadenectomy—A video vignette 机器人右半结肠切除术与D3淋巴结切除术-视频短片
IF 2.9 3区 医学
Colorectal Disease Pub Date : 2025-04-01 DOI: 10.1111/codi.70079
Celia Martinez Alvez, Javier Corral Rubio, Clara Gené Skrabec, Anna Vidal Carné, Ingrid Tapiolas Gracia, David Parés Martinez
{"title":"Robotic right hemicolectomy with D3 lymphadenectomy—A video vignette","authors":"Celia Martinez Alvez,&nbsp;Javier Corral Rubio,&nbsp;Clara Gené Skrabec,&nbsp;Anna Vidal Carné,&nbsp;Ingrid Tapiolas Gracia,&nbsp;David Parés Martinez","doi":"10.1111/codi.70079","DOIUrl":"https://doi.org/10.1111/codi.70079","url":null,"abstract":"","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143741044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robotic left-sided intracorporeal anastomosis with indocyanine green – A video vignette 机器人左侧体内吻合与吲哚菁绿-视频短片
IF 2.9 3区 医学
Colorectal Disease Pub Date : 2025-04-01 DOI: 10.1111/codi.70082
Da Wei Thong, Abraham Jacob, Ruben Rajan
{"title":"Robotic left-sided intracorporeal anastomosis with indocyanine green – A video vignette","authors":"Da Wei Thong,&nbsp;Abraham Jacob,&nbsp;Ruben Rajan","doi":"10.1111/codi.70082","DOIUrl":"https://doi.org/10.1111/codi.70082","url":null,"abstract":"","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143741039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A multicentre prospective single-arm clinical trial to evaluate the treatment outcomes of prophylactic laparoscopic lateral pelvic lymph node dissection for advanced lower rectal cancer 一项多中心前瞻性单臂临床试验,评估预防性腹腔镜盆腔外侧淋巴结清扫术治疗晚期下直肠癌的疗效
IF 2.9 3区 医学
Colorectal Disease Pub Date : 2025-04-01 DOI: 10.1111/codi.70078
Atsushi Hamabe, Junichi Nishimura, Yozo Suzuki, Masayoshi Yasui, Masakazu Ikenaga, Tsukasa Tanida, Shinichi Yoshioka, Yoshihito Ide, Yusuke Takahashi, Hiroshi Takeyama, Takayuki Ogino, Hidekazu Takahashi, Norikatsu Miyoshi, Makoto Fujii, Yuko Ohno, Hirofumi Yamamoto, Kohei Murata, Mamoru Uemura, Yuichiro Doki, Hidetoshi Eguchi
{"title":"A multicentre prospective single-arm clinical trial to evaluate the treatment outcomes of prophylactic laparoscopic lateral pelvic lymph node dissection for advanced lower rectal cancer","authors":"Atsushi Hamabe,&nbsp;Junichi Nishimura,&nbsp;Yozo Suzuki,&nbsp;Masayoshi Yasui,&nbsp;Masakazu Ikenaga,&nbsp;Tsukasa Tanida,&nbsp;Shinichi Yoshioka,&nbsp;Yoshihito Ide,&nbsp;Yusuke Takahashi,&nbsp;Hiroshi Takeyama,&nbsp;Takayuki Ogino,&nbsp;Hidekazu Takahashi,&nbsp;Norikatsu Miyoshi,&nbsp;Makoto Fujii,&nbsp;Yuko Ohno,&nbsp;Hirofumi Yamamoto,&nbsp;Kohei Murata,&nbsp;Mamoru Uemura,&nbsp;Yuichiro Doki,&nbsp;Hidetoshi Eguchi","doi":"10.1111/codi.70078","DOIUrl":"https://doi.org/10.1111/codi.70078","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>There has been no prospective multicentre validation of the treatment outcomes of minimally invasive lateral pelvic lymph node dissection for lower rectal cancer; hence, this prospective study aimed to evaluate the treatment outcomes of prophylactic laparoscopic lateral pelvic lymph node dissection.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Between May 2018 and August 2021, 90 patients with Stage II–III rectal cancer were registered. The clearance range for lateral pelvic lymph node dissection included the lymph nodes around the internal iliac artery and the obturator lymph nodes, while the autonomic nerves were generally preserved. The primary outcome was the incidence of Grade III–IV postoperative complications at discharge. The secondary outcomes were surgical and pathological outcomes, urinary function, sexual function, disease-free survival and overall survival. The experience of each facility and surgeon requirements were set to maintain quality control of lateral pelvic lymph node dissection.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 90 patients, 87 were analysed after exclusion of ineligible patients. There were 30 and 57 cases, respectively, of Stage II and III rectal cancer, among which 17 patients underwent neoadjuvant chemotherapy. The median operating time and blood loss were 472 min and 55 mL, respectively. Postoperative complications were observed in 22 patients (25.3%), and the primary outcome of Grade III postoperative complication was observed in five patients (5.7%). Eight lateral lymph nodes were harvested bilaterally, and lateral lymph node metastasis was observed in 14 patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Prophylactic lateral pelvic lymph node dissection can be safely performed with adequately quality-controlled laparoscopic procedures.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/codi.70078","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143741043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of preoperative enteral immunonutrition in patients undergoing elective colorectal cancer surgery: A systematic review and meta-analysis 择期结直肠癌手术患者术前肠内免疫营养的应用:一项系统回顾和荟萃分析
IF 2.9 3区 医学
Colorectal Disease Pub Date : 2025-03-28 DOI: 10.1111/codi.70061
Tyler McKechnie, Tania Kazi, Ghazal Jessani, Victoria Shi, Niv Sne, Aristithes Doumouras, Dennis Hong, Cagla Eskicioglu
{"title":"The use of preoperative enteral immunonutrition in patients undergoing elective colorectal cancer surgery: A systematic review and meta-analysis","authors":"Tyler McKechnie,&nbsp;Tania Kazi,&nbsp;Ghazal Jessani,&nbsp;Victoria Shi,&nbsp;Niv Sne,&nbsp;Aristithes Doumouras,&nbsp;Dennis Hong,&nbsp;Cagla Eskicioglu","doi":"10.1111/codi.70061","DOIUrl":"https://doi.org/10.1111/codi.70061","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The present systematic review and meta-analysis aims to compare adult patients receiving enteral immunonutrition prior to elective colorectal surgery with those receiving conventional preoperative nutrition.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>MEDLINE, Embase and the Cochrane Central Register of Controlled Trials were searched from database inception to March 2024. Articles were included if they were randomized controlled trials or cohort studies evaluating adult patients undergoing elective colorectal surgery comparing preoperative enteral immunonutrition with conventional preoperative nutrition protocols. Main outcomes of interest included surgical site infection, anastomotic leak, overall postoperative morbidity and postoperative length of stay. An inverse variance random effects meta-analysis was performed. Risk of bias was assessed with Cochrane risk of bias assessment tools. The GRADE approach was conducted to assess quality of evidence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>After reviewing 2508 relevant citations, 10 studies met inclusion criteria. Overall, 1521 patients (mean age 64.9 ± 10.0 years, 49.4% women) received preoperative immunonutrition and 1816 patients (mean age 64.1 ± 11.0 years, 52.1% women) received conventional preoperative nutrition. Across seven studies, there was a non-significant 30% relative risk reduction of surgical site infection (risk ratio 0.70, 95% CI 0.44–1.11, <i>P</i> = 0.13, <i>I</i><sup>2</sup> = 33%) and a non-significant 44% relative risk reduction of anastomotic leak (risk ratio 0.56, 95% CI 0.28–1.10, <i>P</i> = 0.09, <i>I</i><sup>2</sup> = 0%) in the immunonutrition group. Across eight studies, postoperative length of stay was 0.48 days shorter in the immunonutrition group (mean difference −0.48, 95% CI −0.84 to −0.12, <i>P</i> = 0.01, <i>I</i><sup>2</sup> = 53%). GRADE certainty of evidence was low or very low for all outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>While point estimates suggest a likely benefit associated with preoperative enteral immunonutrition, wide corresponding 95% CIs suggest uncertainty remains. Further prospective study is warranted.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/codi.70061","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143726847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robotic colectomy for familial adenomatous polyposis and synchronous right colon cancer: a video vignette 家族性腺瘤性息肉病和同步性右结肠癌的机器人结肠切除术:视频短片
IF 2.9 3区 医学
Colorectal Disease Pub Date : 2025-03-27 DOI: 10.1111/codi.70076
Igor Monsellato, Teresa Gatto, Federico Sangiuolo, Marco Palucci, Celeste del Basso, Fabrizio Panaro
{"title":"Robotic colectomy for familial adenomatous polyposis and synchronous right colon cancer: a video vignette","authors":"Igor Monsellato,&nbsp;Teresa Gatto,&nbsp;Federico Sangiuolo,&nbsp;Marco Palucci,&nbsp;Celeste del Basso,&nbsp;Fabrizio Panaro","doi":"10.1111/codi.70076","DOIUrl":"https://doi.org/10.1111/codi.70076","url":null,"abstract":"","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143707243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing local excision with watch and wait for the management of rectal cancer patients responding to neoadjuvant chemoradiotherapy: Composite endpoint analysis using the win ratio 比较局部切除与观察等待治疗对直肠癌患者新辅助放化疗的反应:使用胜比的综合终点分析
IF 2.9 3区 医学
Colorectal Disease Pub Date : 2025-03-27 DOI: 10.1111/codi.70077
Giulia Capelli, Giulia Lorenzoni, Maria Vittoria Chiaruttini, Paolo Delrio, Mario Guerrieri, Monica Ortenzi, Nicola Cillara, Angelo Restivo, Simona Deidda, Antonino Spinelli, Carmela Romano, Francesco Bianco, Giacomo Sarzo, Dajana Glavas, Emilio Morpurgo, Claudio Belluco, Elisa Palazzari, Giuditta Chiloiro, Elisa Meldolesi, Claudio Coco, Donato Paolo Pafundi, Cosimo Feleppa, Carlo Aschele, Michele Bonomo, Andrea Muratore, Alfredo Mellano, Germana Chiaulon, Francesca Bergamo, Maria Antonietta Gambacorta, Daniela Rega, Dario Gregori, Gaya Spolverato, Salvatore Pucciarelli
{"title":"Comparing local excision with watch and wait for the management of rectal cancer patients responding to neoadjuvant chemoradiotherapy: Composite endpoint analysis using the win ratio","authors":"Giulia Capelli,&nbsp;Giulia Lorenzoni,&nbsp;Maria Vittoria Chiaruttini,&nbsp;Paolo Delrio,&nbsp;Mario Guerrieri,&nbsp;Monica Ortenzi,&nbsp;Nicola Cillara,&nbsp;Angelo Restivo,&nbsp;Simona Deidda,&nbsp;Antonino Spinelli,&nbsp;Carmela Romano,&nbsp;Francesco Bianco,&nbsp;Giacomo Sarzo,&nbsp;Dajana Glavas,&nbsp;Emilio Morpurgo,&nbsp;Claudio Belluco,&nbsp;Elisa Palazzari,&nbsp;Giuditta Chiloiro,&nbsp;Elisa Meldolesi,&nbsp;Claudio Coco,&nbsp;Donato Paolo Pafundi,&nbsp;Cosimo Feleppa,&nbsp;Carlo Aschele,&nbsp;Michele Bonomo,&nbsp;Andrea Muratore,&nbsp;Alfredo Mellano,&nbsp;Germana Chiaulon,&nbsp;Francesca Bergamo,&nbsp;Maria Antonietta Gambacorta,&nbsp;Daniela Rega,&nbsp;Dario Gregori,&nbsp;Gaya Spolverato,&nbsp;Salvatore Pucciarelli","doi":"10.1111/codi.70077","DOIUrl":"https://doi.org/10.1111/codi.70077","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The aim of this work was to apply the ‘win ratio’ to compare the outcomes of rectal-sparing approaches [watch and wait (WW) and local excision (LE)] in the management of locally advanced rectal cancer responding to neoadjuvant chemoradiotherapy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Patients enrolled in the ReSARCh study (NCT02710812) between 2016 and 2021 were divided into two cohorts (WW vs. LE). The win ratio was calculated by dividing the number of successes (or wins) in the WW group by the number of successes in the LE group on matched pairs. Oncological outcomes (overall survival, distant and local recurrence), presence of a stoma and rectum not preserved were considered as outcomes of interest.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Overall, 108 (62.1%) patients underwent LE and 66 (37.9%) WW. Patients who underwent WW were more likely to have a complete clinical response (cCR) at restaging [i.e. ycT = 0: <i>n</i> = 51 (80%) for WW vs. <i>n</i> = 45 (42%) for LE, <i>p</i> &lt; 0.001]. After matching for age, sex, distance from the anal verge and T stage at restaging, i.e. ycT, 57 pairs of patients were identified. The overall win ratio considering only oncological outcomes was 0.4 (95% CI 0.02–0.94). The disadvantage of WW was mainly due to a higher rate of local recurrences. The overall win ratio considering oncological outcomes, presence of a stoma and rectum not preserved was 0.6 (95% CI 0.04–1.38), indicating a potential disadvantage for WW, but with wide confidence intervals suggesting uncertainty.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>LE may have an advantage in terms of local recurrence rates compared with WW, potentially conferring a survival benefit. These results should be confirmed in further prospective randomized trials.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143707635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EXPRESSION OF CONCERN: Medium-Term Results of Stapled Transanal Rectal Resection (STARR) for Obstructed Defecation and Symptomatic Rectal-Anal Intussusception 关注的表达:经肛直肠吻合器切除术(STARR)治疗排便障碍和症状性直肠-肛门肠套叠的中期结果
IF 2.9 3区 医学
Colorectal Disease Pub Date : 2025-03-25 DOI: 10.1111/codi.70065
{"title":"EXPRESSION OF CONCERN: Medium-Term Results of Stapled Transanal Rectal Resection (STARR) for Obstructed Defecation and Symptomatic Rectal-Anal Intussusception","authors":"","doi":"10.1111/codi.70065","DOIUrl":"https://doi.org/10.1111/codi.70065","url":null,"abstract":"<p><b>EXPRESSION OF CONCERN:</b> A.C. Goede, D. Glancy, H. Carter, A. Mills, K. Mabey, and A.R. Dixon, “Medium-Term Results of Stapled Transanal Rectal Resection (STARR) for Obstructed Defecation and Symptomatic Rectal-Anal Intussusception,” <i>Colorectal Disease</i> 13, no. 9 (2011): 1052–1057, https://doi.org/10.1111/j.1463-1318.2010.02405.x.</p><p>This Expression of Concern is for the above article, published online on 31 August 2010 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editors-in-Chief, Sue Clark and Neil Smart; The Association of Coloproctology of Great Britain and Ireland; and John Wiley &amp; Sons Ltd. The Expression of Concern has been agreed due to concerns raised regarding the legitimacy of the data reported and allegations of a lack of informed consent from patients who underwent the surgical procedure reported within. The investigation into these concerns is ongoing. Therefore, the journal has decided to issue an Expression of Concern to inform and alert the readers.</p>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/codi.70065","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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