Lawrence B. Brown, Shannon N. Radomski, Miloslawa Stem, Susan L. Gearhart, Haniee Chung, Vincent J. Obias, Alodia Gabre-Kidan
{"title":"Conversion following minimally invasive attempt at simultaneous colorectal and liver resection does not affect 30-day postoperative overall morbidity","authors":"Lawrence B. Brown, Shannon N. Radomski, Miloslawa Stem, Susan L. Gearhart, Haniee Chung, Vincent J. Obias, Alodia Gabre-Kidan","doi":"10.1111/codi.70128","DOIUrl":"https://doi.org/10.1111/codi.70128","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Over the past decade, minimally invasive surgery (MIS) approaches have been increasingly utilized for simultaneous colorectal cancer (CRC) and colorectal liver metastasis (CRLM). However, the impact of conversion to open surgery during MIS remains unclear. This study evaluates 30-day postoperative overall morbidity in patients undergoing simultaneous resection for CRC and CRLM tumours.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>We utilized the American College of Surgeons National Surgical Quality Improvement Program database from 2013 to 2022. Adults ≥18 years who underwent surgery for a simultaneous resection of CRC and CRLM were included. Propensity score matching was used to ascertain differences in surgical outcomes between those who underwent a planned open procedure and those who had an MIS that was converted to open.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 2306 patients were included in our study. Of these, the majority underwent a planned open procedure (<i>n</i> = 1831, 79.4%). Of the patients who underwent an MIS approach (<i>n</i> = 381, 20.6%), the majority had a laparoscopic procedure (<i>n</i> = 272, 71.4%) compared to a robotic approach (<i>n</i> = 109, 28.6%). There were significant differences between the three surgical groups by age group (<i>P</i> = 0.012), race (<i>P</i> < 0.001) and risk of procedure (<i>P</i> < 0.001). After propensity score matching, 94 patients remained in the planned open and MIS with conversion groups. There were no significant differences in 30-day postoperative outcomes between these two surgical groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Postoperative surgical outcomes between planned open and MIS converted to open procedures were similar. These findings imply that an MIS approach can be attempted for simultaneous resection of CRC and CRLM without adverse outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 6","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Phil Meister, Samira Vestweber, Jan Neuhaus, Marc A. Reschke, Ulf Neumann, Andreas D. Rink
{"title":"Surgical outcomes of colorectal cancer surgery in transplant recipients: A matched case–control study","authors":"Phil Meister, Samira Vestweber, Jan Neuhaus, Marc A. Reschke, Ulf Neumann, Andreas D. Rink","doi":"10.1111/codi.70133","DOIUrl":"https://doi.org/10.1111/codi.70133","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The incidence of colorectal carcinoma (CRC) in transplant (TX) recipients is higher than in the general population. Registry data indicate inferior oncological outcomes for this population. While the general surgical risk is increased in TX recipients, the risk associated with elective CRC surgery in this population is not well investigated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>TX recipients, who underwent elective surgical treatment for CRC at our specialized centre from 2008 to 2024 were included in this case–control study. The controls were randomly selected from our CRC database and matched according to tumour location and Charlson Comorbidity Index. Outcomes assessed included intensive care unit stay, in-hospital mortality, length of hospital stay and major morbidity (defined as Clavien–Dindo Grade ≥3).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study included 24 TX recipients. Ten patients had had either liver or kidney TX, three patients had undergone lung TX and one patient heart TX. The mean time interval between transplantation surgery and CRC was 8.82 years. Morbidity was significantly higher in the TX group (54.2% vs. 8.3%, <i>P</i> = 0.001; OR 13.0, 95% CI 2.5–68,1, <i>P</i> = 0.002) and length of hospital stay was significantly longer (25 vs. 9 days, <i>P</i> = 0.001; OR 9.09, 95% CI 1.4–16.7, <i>P</i> = 0.022) for TX patients. No significant differences in mortality and intensive care unit stay were observed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The risk of surgery for CRC in TX patients is significantly increased. Treatment decisions should involve TX experts to develop a tailored and considered treatment plan.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 6","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/codi.70133","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sonal Kumar, Justin Dourado, Marcus Oosenbrug, Juan J. Nogueras, Giovanna Dasilva
{"title":"Perineal approach to the presacral cyst—A video vignette","authors":"Sonal Kumar, Justin Dourado, Marcus Oosenbrug, Juan J. Nogueras, Giovanna Dasilva","doi":"10.1111/codi.70131","DOIUrl":"https://doi.org/10.1111/codi.70131","url":null,"abstract":"","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 6","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kumail Jaffry, Rathin Gosavi, Ratheesraj Ratinam, James Lim, Thomas Suhardja, Yeng Kwang Tay, Asiri Arachchi, Hanumant Chouhan, Chaminda Saranasuriya, William Teoh, Vignesh Narasimhan, Thang Chien Nguyen
{"title":"Kono-S anastomosis in stricturing Crohn's disease — How we do it: A step-by-step approach for surgical trainees — A Video Vignette","authors":"Kumail Jaffry, Rathin Gosavi, Ratheesraj Ratinam, James Lim, Thomas Suhardja, Yeng Kwang Tay, Asiri Arachchi, Hanumant Chouhan, Chaminda Saranasuriya, William Teoh, Vignesh Narasimhan, Thang Chien Nguyen","doi":"10.1111/codi.70127","DOIUrl":"https://doi.org/10.1111/codi.70127","url":null,"abstract":"","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 6","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144171417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jean-Baptiste Pretalli, Dewi Vernerey, Philippe Evrard, Astrid Pozet, Anne-Laure Clairet, Stéphane Benoist, Mehdi Karoui, Eddy Cotte, Bruno Heyd, Zaher Lakkis, FLUOCOL Study Group
{"title":"Intraoperative indocyanine green fluorescence angiography in colorectal surgery to prevent anastomotic leakage: A single-blind phase III multicentre randomized controlled trial (FLUOCOL-01/FRENCH 21/GRECCAR 19 intergroup trial)","authors":"Jean-Baptiste Pretalli, Dewi Vernerey, Philippe Evrard, Astrid Pozet, Anne-Laure Clairet, Stéphane Benoist, Mehdi Karoui, Eddy Cotte, Bruno Heyd, Zaher Lakkis, FLUOCOL Study Group","doi":"10.1111/codi.70119","DOIUrl":"https://doi.org/10.1111/codi.70119","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Anastomotic leak (AL) is a major problem in colorectal surgery, and its prevention is crucial for patient safety. The scientific literature shows that optimal anastomotic perfusion is essential for anastomotic healing. However, in cases of left colon or rectal cancer requiring high vessel ligation for oncological reasons, anastomotic blood supply relies mainly on the pericolic arterial arcades. Consequently, assessing anastomotic perfusion using intraoperative fluorescence angiography with indocyanine green might be relevant to reduce the risk of AL. Although evidence of its positive impact on the risk of AL is growing in the literature, most studies are descriptive prospective cohorts or retrospective comparative series with controversial findings. Furthermore, no other studies specifically address left-sided colon or high rectal tumours. FLUOCOL-1 is a large multicentre randomized controlled trial (RCT) that aims to demonstrate that assessing anastomotic perfusion using intraoperative fluorescence angiography with indocyanine green will reduce ALs in left-sided or high anterior resections with intraperitoneal anastomosis</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>FLUOCOL-1 is a French multicentre, single-blind, randomized, two-arm, phase III superiority clinical trial. Patients will be randomized in a 1:1 ratio to either the intervention group (FLUO+) or the control group (FLUO−). A total of 1010 patients will be randomized. The primary endpoint is the occurrence of an AL within 90 days postsurgery. AL is defined as any anastomotic dehiscence with leakage into the pelvic cavity diagnosed by imaging or surgical exploration, or any isolated pelvic organ-space infection with no evidence of fistula, as defined by the International Study Group of Rectal Cancer.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Prevention of AL is one of the most important questions to be addressed in colorectal surgery. The FLUOCOL-1 multicentre RCT described herein aims to demonstrate that assessment of anastomotic perfusion using intraoperative fluorescence angiography with indocyanine green will reduce ALs in certain resections with intraperitoneal anastomosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/codi.70119","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144135848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A multicentre prospective study of anal function after laparoscopic ultra-low rectal cancer surgery using a mixed-effects model","authors":"Makoto Takahashi, Kazuhiro Sakamoto, Yuichiro Tsukada, Shingo Kawano, Jun Watanabe, Yosuke Fukunaga, Yasumitsu Hirano, Hiroki Hamamoto, Masanori Yoshimitsu, Hisanaga Horie, Nobuhisa Matsuhashi, Yoshiaki Kuriu, Shuntaro Nagai, Madoka Hamada, Shinichi Yoshioka, Shinobu Ohnuma, Tamuro Hayama, Koki Otsuka, Yusuke Inoue, Kazuki Ueda, Yuji Toiyama, Satoshi Maruyama, Shigeki Yamaguchi, Keitaro Tanaka, Motoko Suzuki, Toshihiro Misumi, Takeshi Naitoh, Masahiko Watanabe, Masaaki Ito, Ultimate Trial Group","doi":"10.1111/codi.70129","DOIUrl":"https://doi.org/10.1111/codi.70129","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Abdominoperineal resection with permanent colostomy has historically been performed for very low rectal cancer located near the anal canal. Anus-preserving surgeries, such as intersphincteric resection (ISR) and low anterior resection (LAR), have recently become more common. However, postoperative anal function is a concern in these surgeries when the anastomosis is very low. The aim of this study was to examine changes in anal function and factors that worsen anal function after surgery for rectal cancer.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>A multicentre (47 facilities), non-randomized, single-arm phase II trial was conducted prospectively using the Wexner score questionnaire between 2014 and 2017. A total of 278 patients who underwent laparoscopic surgery for clinical Stage I very low rectal cancer were analysed using a mixed-effects model.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Anal function temporarily worsened 3 months after surgery, but gradually recovered and spontaneously returned to an acceptable level in 3 years. In a comparison of surgical procedures, anal function was significantly better after LAR than after any type of ISR. There was little difference in anal function after total ISR, subtotal ISR and partial ISR. In the mixed-effects model analysis, ISR and older age (≥75 years) were identified as independent factors that worsened postoperative anal function.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The results showed early deterioration of anal function followed by gradual improvement to an acceptable level after surgery. There is a higher risk of poor postoperative anal function after ISR and in older patients, and these risk factors should be communicated to patients when obtaining consent for the surgery.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/codi.70129","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144135847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long-term outcomes and prognostic factor of metachronous para-aortic lymph node metastasis in colorectal cancer","authors":"Takeru Matsuda, Sono Ito, Yusuke Kinugasa, Soichiro Ishihara, Akio Shiomi, Yukihide Kanemitsu, Yoshihiro Kakeji, Yoichi Ajioka","doi":"10.1111/codi.70124","DOIUrl":"https://doi.org/10.1111/codi.70124","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Despite the relatively rare incidence of para-aortic lymph node metastasis (PALNM) after surgery for colorectal cancer, it is often fatal, and treatment strategy is still debated. This study aimed to investigate the long-term outcomes of patients with metachronous PALNM and their prognostic factors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Thirty-six institutions belonging to the Japanese Society for Cancer of the Colon and Rectum participated in this retrospective cohort study. A total of 148 patients with metachronous PALNM after resection of primary colorectal cancer between January 2011 and December 2015 were included in the analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 148 patients, 37 received PALNM resection, whereas 111 did not. The primary tumour characteristics were not different between the resection and non-resection groups. The median number of PALNMs was significantly larger and synchronous metastasis other than PALNM was more frequent in the non-resection group than in the resection group (2 vs. 1, <i>P</i> = 0.030; 71.2% vs. 29.7%, <i>P</i> < 0.001). The 5-year overall survival rate in the whole cohort was 30.6%, which was significantly higher in the resection group than in the non-resection group (<i>P</i> < 0.0001). The resection method of PALNM did not affect survival. Undifferentiated tumour, ≥4 PALNMs, synchronous metastasis other than PALNM, and non-resection of PALNM were significant unfavourable prognostic factors in the multivariate Cox regression analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>PALNM resection appears desirable when it is feasible in patients with metachronous PALNM. However, surgeons should also consider unfavourable prognostic factors including undifferentiated tumour, ≥4 PALNMs and synchronous metastasis other than PALNM.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144108894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Justin T. Brady, Jesse P. Wright, Jennifer S. Davids, Scott R. Kelley, Karim Alavi, Sharon L. Stein, John R. T. Monson, Zhaomin Xu
{"title":"The impact of nonoperative management of rectal cancer on colon and rectal surgery residents in the United States","authors":"Justin T. Brady, Jesse P. Wright, Jennifer S. Davids, Scott R. Kelley, Karim Alavi, Sharon L. Stein, John R. T. Monson, Zhaomin Xu","doi":"10.1111/codi.70125","DOIUrl":"https://doi.org/10.1111/codi.70125","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>There is increasing adoption of nonoperative management of rectal cancer; however, the extent to which trainees are proficient in nonoperative management is unclear. The aim of this work was to describe the exposure of recent colorectal resident graduates to nonoperative management, their comfort level in assessing clinical responses and their comfort in performing rectal cancer surgeries.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>This was an online survey of Accreditation Council for Graduate Medical Education-certified colorectal surgery residency graduates of training programmes in 2020, 2021 and 2022 utilizing their respective WhatsApp class chat groups. Data on resident comfort in assessing complete or near complete clinical response as part of nonoperative management, adoption in practice and perceived effects on rectal cancer operative experience were collected.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Forty five graduates responded, with 83.3% exposed to nonoperative management in training. Eighty five per cent utilize nonoperative management in their own practices and 37.1% felt it had a negative impact on preparing them for rectal cancer surgeries. While 82.4% felt comfortable assessing a complete clinical response, only 61.8% felt comfortable assessing a near complete response. Residents who perceived a positive effect on their training felt more comfortable assessing a complete or near complete response.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Most recent graduates were exposed to nonoperative management in training and utilize it in practice, although many did not feel comfortable assessing a near complete response. A significant portion felt it had a negative impact on their experience and quantity of rectal cancer surgeries. This suggests a need to improve colorectal resident education in nonoperative management of rectal cancer while simultaneously preserving surgical experience for trainees.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144100875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum to “Accuracy of preoperative staging with multidetector computed tomography in colon cancer”","authors":"","doi":"10.1111/codi.70123","DOIUrl":"https://doi.org/10.1111/codi.70123","url":null,"abstract":"<p>Olsen ASF, Gundestrup AK, Kleif J, Thanon T, Bertelsen CA. Accuracy of preoperative staging with multidetector computed tomography in colon cancer. Colorectal Dis. 2021;23:680-8.</p><p>Throughout the text, locally advanced colon cancer was incorrectly defined as T3 with 5 mm or more extramural tumour invasion (ETI) or T4. The correct definition was: “as T3 with more than 5 mm extramural tumour invasion (ETI) or T4”. This should have read as follows:</p><p>In paragraph 1 of the “Introduction” section: “Neoadjuvant chemotherapy might be beneficial to the small subgroup of patients with locally advanced colon cancer defined as clinical (c)T3 with more than 5 mm extramural tumour invasion (ETI) or cT4 [1–3].”</p><p>In paragraph 3 of the “Introduction” section: “Both studies and a metanalysis [12] concluded that MDCT was able to identify patients with locally advanced colon cancer (T3 with extramural tumour invasion of more than 5 mm or T4) and be reliable as the decision-making tool for including patients in the trial, but it is questionable whether these results can be applied to daily practice.”</p><p>In paragraph 4 of the “Methods” section: “The primary outcome of the study was the accuracy of MDCT to preoperatively identify those patients with locally advanced disease (defined as pT3 with ETI of more than 5 mm or pT4 tumour).”</p><p>In Figure 1, “ETI of more than 5 mm or T4” in the two boxes.</p><p>In the explaining text of Table 2: “Locally advanced disease was defined clinical or histopathologic as T3 tumour with an extramural tumour invasion of more than 5 mm or a T4 tumour.”</p><p>In paragraph 1 of the “Discussion” section: “The results show that MDCT can detect invasion beyond the muscularis propria (pT3–4 versus pT1–2) with a sensitivity of 73%, but it remains a challenge to identify patients with pT4 or pT3 with extramural tumour invasion of more than 5 mm, and especially to predict lymph node metastasis and thus UICC Stage I.”</p><p>We apologize for this error.</p>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/codi.70123","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kaveh Dehlaghi Jadid, Soran Gadan, Göran Wallin, Caroline Nordenvall, Sol Erika Boman, Ida Hed Myrberg, Peter Matthiessen
{"title":"Does socioeconomic status influence the choice of surgical technique in abdominal rectal cancer surgery?","authors":"Kaveh Dehlaghi Jadid, Soran Gadan, Göran Wallin, Caroline Nordenvall, Sol Erika Boman, Ida Hed Myrberg, Peter Matthiessen","doi":"10.1111/codi.70111","DOIUrl":"https://doi.org/10.1111/codi.70111","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study aimed to estimate the impact of socioeconomic status on the probability of receiving open (OPEN) or minimally invasive surgery (MIS) for curative abdominal rectal cancer resection.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>All patients diagnosed with rectal cancer clinical Stage I–III during the period 2010–2021 who underwent curative abdominal resection surgery, MIS or OPEN, were included. Patients were identified in the Colorectal Cancer Database, a register-linkage based on the Swedish Colorectal Cancer Register and linked to several national Swedish health-related and demographic registers. Socioeconomic factors, sex, patient and tumour characteristics, number of previous surgical procedures and category of hospital were collected. Exposures were level of education (categorized as 6–9, 10–12, >12 years), household income (quartiles 1–4) and country of birth (Sweden, Nordic countries outside Sweden, Europe outside the Nordic countries, outside Europe), and outcome was MIS or OPEN. Multivariable logistic regression models were fitted for each exposure, adjusted for age, sex, cT and cN, level of tumour, and number of previous abdominal surgical procedures.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 13 778 patients were included of whom 43.6% underwent MIS (<i>n</i> = 6007) and 56.4% OPEN (<i>n</i> = 7771). Highest level of education (OR for highest vs. lowest level of education 1.15; 95% CI 1.03–1.29) and highest household income quartile (OR for highest vs. lowest household income quartile 1.27; 95% CI 1.12–1.44) increased the likelihood of receiving MIS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Despite the tax-financed healthcare system in Sweden, rectal cancer patients with the highest level of education and the highest household income had an increased probability of receiving MIS.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"27 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/codi.70111","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}