Survivorship issues in long-term survivors of locally recurrent rectal cancer: A qualitative study

IF 2.9 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Colorectal Disease Pub Date : 2025-03-20 DOI:10.1111/codi.70051

Niamh McKigney, Sophia Waldenstedt, Elisabeth Gonzalez, Jan M. van Rees, Henriette Vind Thaysen, Eva Angenete, Galina Velikova, Julia M. Brown, Deena P. Harji, LRRC-QoL Collaborators

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引用次数: 0

Abstract

Aim

There are increasing numbers of long-term survivors following curative treatment for locally recurrent rectal cancer (LRRC); however, their experiences remain relatively underreported. The aim of this qualitative study was to identify the long-term survivorship issues relevant to these patients.

Method

Adults who remained disease free >3 years following treatment for LRRC were invited to participate in an international multicentre study. Semistructured qualitative interviews were conducted either in person, via telephone or via Microsoft Teams and were analysed using a framework method of thematic analysis.

Results

A total of 26 participants were recruited from 11 sites in seven countries. Sixteen (61.5%) participants were male, the median age was 70.5 (33.0–85.0) years, participants were a median of 5.0 (3.0–17.0) years posttreatment, most had undergone surgery for LRRC (n = 24, 92.3%), two participants received neoadjuvant chemo/radiation for LRRC with a complete response. Eight major survivorship themes were identified: (1) experience of long-term follow-up care, (2) unmet needs and areas for improvement, (3) long-term physical effects of cancer and treatment, (4) living with a stoma, urostomy or other urinary device, (5) long-term psychological impact, (6) impact on sexual function and intimate relationships, (7) impact on daily life and (8) feelings surrounding life now, adapting and the future.

Conclusion

Participants experienced a wide range of long-term survivorship issues, reflecting the complexity of both LRRC and its treatment. Despite this, most had adapted well. Further work regarding survivorship care in LRRC is required to address the unmet needs and issues highlighted in this study, such as support regarding sexual function.

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局部复发直肠癌长期幸存者的生存问题：一项定性研究。

目的：局部复发性直肠癌（LRRC）根治性治疗后的长期幸存者数量不断增加；然而，他们的经历仍然相对较少报道。本定性研究的目的是确定与这些患者相关的长期生存问题。方法：在LRRC治疗3年后仍无疾病的成人被邀请参加一项国际多中心研究。半结构化的定性访谈可以亲自、通过电话或通过微软团队进行，并使用主题分析的框架方法进行分析。结果：从7个国家的11个地点共招募了26名参与者。16名（61.5%）参与者为男性，中位年龄为70.5（33.0-85.0）岁，治疗后中位年龄为5.0（3.0-17.0）岁，大多数参与者接受了LRRC手术（n = 24, 92.3%）， 2名参与者接受了LRRC的新辅助化疗/放疗，完全缓解。确定了八个主要的生存主题：(1)长期随访护理的经历，(2)未满足的需求和需要改进的领域，(3)癌症和治疗的长期身体影响，(4)生活在造口术、尿路造口术或其他泌尿装置中，(5)长期心理影响，(6)对性功能和亲密关系的影响，(7)对日常生活的影响，以及(8)对现在、适应和未来生活的感受。结论：参与者经历了广泛的长期生存问题，反映了LRRC及其治疗的复杂性。尽管如此，大多数都适应得很好。LRRC需要进一步开展关于幸存者护理的工作，以解决未满足的需求和本研究中强调的问题，例如对性功能的支持。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Colorectal Disease 医学-胃肠肝病学

CiteScore

6.10

自引率

11.80%

发文量

406

审稿时长

1.5 months

期刊介绍： Diseases of the colon and rectum are common and offer a number of exciting challenges. Clinical, diagnostic and basic science research is expanding rapidly. There is increasing demand from purchasers of health care and patients for clinicians to keep abreast of the latest research and developments, and to translate these into routine practice. Technological advances in diagnosis, surgical technique, new pharmaceuticals, molecular genetics and other basic sciences have transformed many aspects of how these diseases are managed. Such progress will accelerate. Colorectal Disease offers a real benefit to subscribers and authors. It is first and foremost a vehicle for publishing original research relating to the demanding, rapidly expanding field of colorectal diseases. Essential for surgeons, pathologists, oncologists, gastroenterologists and health professionals caring for patients with a disease of the lower GI tract, Colorectal Disease furthers education and inter-professional development by including regular review articles and discussions of current controversies. Note that the journal does not usually accept paediatric surgical papers.