Clinical Physiology and Functional Imaging最新文献

{"title":"Minute-level ECG-derived autonomic dynamics around obstructive apnea events: A peri-event analysis of the PhysioNet apnea-ECG database","authors":"Pratyush Kumar,&nbsp;Kumar Abhishek,&nbsp;Pankti Shah,&nbsp;Munaf Siyamwala,&nbsp;Michael J. Waxman","doi":"10.1111/cpf.70080","DOIUrl":"10.1111/cpf.70080","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Obstructive sleep apnea (OSA) is linked to arrhythmia and cardiovascular morbidity, but the cardiac response to individual obstructive events is incompletely characterised at minute-scale resolution. We aimed to determine whether ECG-derived autonomic features distinguish apnea from nonapnea minutes and whether these features change before scored event onset.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We performed a secondary analysis of the PhysioNet Apnea-ECG learning set (34 subjects after exclusion of one duplicated recording; 30 male, 4 female; mean age 47.0 ± 9.7 years; AHI 0–82.4 events/h). For each 1-min segment, we computed mean heart rate, SDNN, RMSSD, pNN50 and RR irregularity rate from QRS-derived RR intervals. Minutes were classified as baseline, preapnea, apnea, or post-apnea and associations tested using mixed-effects regression with subject random intercepts.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The analytic dataset comprised 17,004 min; 38.2% were apnea minutes. Apnea minutes showed a heart rate reduction of −2.66 bpm (95% CI: −2.92 to −2.41, <i>p</i> &lt; 0.001) and an RMSSD increase of +19 ms (95% CI: 15–23, <i>p</i> &lt; 0.001) versus baseline. In multivariable modelling, SDNN was the dominant feature (<i>β</i> = +0.472); RMSSD showed a sign reversal (<i>β</i> = −0.416) and reciprocal logistic odds ratios (SDNN OR 134.9 vs. RMSSD OR 0.034) consistent with substantial collinearity. Preapnea minutes showed directionally similar but smaller changes; post-apnea minutes showed partial normalisation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Obstructive apnea is associated with a reproducible minute-level autonomic signature of bradycardia and increased RR variability, with detectable shifts preceding scored event onset. Variability metrics, particularly SDNN, contribute more than mean heart rate. Findings require validation in cohorts with linked cardiovascular outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"46 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148351055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of conventional ultrasound-based carotid grading system in assessing disease activity and monitoring progression in Takayasu arteritis","authors":"Xuelan Li,&nbsp;Chenyang Zhao,&nbsp;Juan Du,&nbsp;Fengju Liu,&nbsp;Jie Chen","doi":"10.1111/cpf.70077","DOIUrl":"10.1111/cpf.70077","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aimed to evaluate and validate the utility of a conventional ultrasound-based carotid grading system in assessing disease activity in Takayasu arteritis (TA) with carotid artery involvement, distinguishing between active and inactive patients, and monitoring therapeutic response.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The 108 patients were classified into the clinically-active group (CAG) and the clinically-inactive group (CIG), and were further classified into Grades I–V according to carotid ultrasound imaging characteristics, with Grades I, II, and V categorized as the ultrasound-active group (UAG), and Grades III and IV as the ultrasound-inactive group (UIG). Intergroup differences were compared, and the diagnostic performance of the ultrasound grading system for disease activity was evaluated by the ROC curve analysis. Treatment response assessed in 68 follow-up patients based on ultrasound grading.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The CAG exhibited higher inflammatory markers and greater carotid wall thickness (<i>p</i> &lt; 0.05). Grades I, II, and V predominated in the CAG, whereas Grades III and IV were more frequent in the CIG. Compared to the UIG, the UAG showed significantly elevated ESR, CRP, C3, and IgM, and thicker carotid walls (<i>p</i> &lt; 0.05). The ultrasound grading system achieved an AUC of 0.710 for identifying clinical activity in TA. Combined with carotid wall thickness, diagnostic performance surpassed either parameter alone. Among 68 follow-up patients, the UAG had higher inflammatory markers and greater wall thickness at baseline but demonstrated more pronounced improvement in disease activity after treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Conventional ultrasound is a reliable tool for characterizing vascular wall inflammation and monitoring therapeutic response in TA patients with carotid artery involvement.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"46 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cpf.70077","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148350991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Defining reference intervals for submaximal cardiopulmonary exercise testing-derived gas-exchange derived pulmonary capacitance in older adults","authors":"Yoshio Tatsuoka,&nbsp;Megan Longley,&nbsp;Dean MacCarter,&nbsp;Zyad J. Carr","doi":"10.1111/cpf.70076","DOIUrl":"10.1111/cpf.70076","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Gas-exchange derived pulmonary capacitance (GXCAP) is a non-invasive index of pulmonary arterial capacitance obtainable from submaximal cardiopulmonary exercise testing (CPET), but reference intervals in older adults, a key target population, are lacking.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A secondary analysis of an open-label clinical device trial, including 207 adults ≥ 60 years undergoing elective non-cardiac surgery was performed. Submaximal CPET with the Shape II system provided peak GXCAP, GXCAP–time slope, and GXCAP–VO₂ slope. Sex-specific empirical 95% reference intervals (2.5th–97.5th percentiles) and indirect reference intervals were calculated using the refineR algorithm, which models the latent healthy subpopulation within routine data. Associations with age and sex were examined using correlation and group comparisons.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The analytic cohort comprised 207 nonsmoking participants (119 males, 88 females). Males demonstrated higher peak GXCAP and steeper GXCAP–time and GXCAP–VO₂ slopes than females. Age was modestly and inversely associated with peak GXCAP and GXCAP–time slope. Empirical reference intervals were wide and right-skewed, whereas refineR produced narrower, physiologically plausible intervals, for example, peak GXCAP 144.9–810.0 mL.mmHg (overall), with higher upper limits in males.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In older adults undergoing preoperative evaluation, GXCAP metrics show clear sex differences. Indirect, refineR-based, reference intervals provide stable, clinically interpretable ranges that may enhance the use of GXCAP for noninvasively assessing pulmonary arterial capacitance in submaximal CPET. GXCAP derivatives (GXCAP–time slope and GXCAP–VO₂ slope were introduced and may offer distinct advantages in submaximal cardiopulmonary exercise testing.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Trial Registration</h3>\u0000 \u0000 <p>NCT05743673, Principal Investigator: Zyad J. Carr, M.D.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"46 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148307322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The combination of low-intensity resistance exercise and electrical muscle stimulation effectively enhances executive function in men","authors":"Kento Dora,&nbsp;Su Yang,&nbsp;I. Wayan Yuuki,&nbsp;Kousei Tachi,&nbsp;Kaito Hashimoto,&nbsp;Teppei Matsumura,&nbsp;Naokazu Miyamoto,&nbsp;Takeshi Hashimoto","doi":"10.1111/cpf.70075","DOIUrl":"10.1111/cpf.70075","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Resistance exercise enhances executive function (EF) more effectively at moderate or higher intensities than at low intensity resistance exercise (LRE), probably with increased neural activity and lactate production to meet brain energy demands. Given that LRE remains widely applicable with less perceived exertion, and electrical muscle stimulation (EMS) increases lactate production and neural activation, we investigated whether combining LRE with EMS (LRE-EMS) effectively enhances EF, without increasing perceived exertion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>A crossover randomized study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Seventeen young men participated in a crossover randomized study to assess the cognitive effects of LRE alone, EMS alone, and LRE-EMS. The LRE protocol involved knee extensions at 40% one-repetition maximum for 4 sets of 10 repetitions. During the EMS condition, the participants remained seated for 260 s to match the duration of the other conditions, with EMS applied to the lower limb muscles. Subjective perceptions of exertion and fatigue during exercise were recorded.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>IC and lactate were measured at baseline, immediately postexercise, and 15 min postexercise. The LRE condition did not significantly increase IC (<i>p</i> = 0.100), whereas LRE-EMS resulted in significant IC improvements immediately and 15 min postexercise (both <i>p</i> &lt; 0.001), with greater lactate increases compared to LRE and EMS. EMS demonstrated significant IC improvement at 15 min postexercise (<i>p</i> = 0.022).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Perceived exertion and fatigue were greater with LRE-EMS compared with LRE and EMS. These findings suggest that LRE combined with EMS and EMS alone are effective strategies for cognitive improvement, but increased perceived exertion still exists.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"46 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cpf.70075","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148307236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In sphincter of Oddi patients, amelioration of pain is primarily associated with common bile duct dilation rather than hepatobiliary scintigraphy excretion time or alanine amino transferase – a single centre, retrospective study","authors":"Marina Kegnæs,&nbsp;Daniel Mønsted Shabanzadeh,&nbsp;John Gásdal Karstensen,&nbsp;Camilla Nøjgaard,&nbsp;Mikkel Werge,&nbsp;Søren Møller,&nbsp;Lise Lotte Gluud,&nbsp;Srdan Novovic","doi":"10.1111/cpf.70074","DOIUrl":"10.1111/cpf.70074","url":null,"abstract":"<p>There are few reliable predictors for reduced pain after biliary sphincterotomy or medical therapy in patients with sphincter of Oddi dysfunction (SOD). We explored whether prolonged intestinal bile excretion time, dilated common bile duct (CBD) diameter, or elevated alanine aminotransferase (ALT) were associated with reduced pain after treatment for SOD. This is a retrospective, single-centre study. Consecutive patients suspected of SOD were identified and screened. Medical treatment for SOD followed institutional standards in line with the Regional pain medication guidelines. The primary outcome was potential prognostic markers for reduced pain. In the biliary sphincterotomy group (<i>n</i> = 34), 85% patients experienced reduced pain when evaluated in the outpatient clinic, while 60% of patients receiving medical therapy (<i>n</i> = 159) experienced reduced pain (<i>p</i> = 0.009). No association was found between the hepatobiliary scintigraphy excretion time nor ALT and reduced pain in either treatment group. However, a dilated CBD was associated with reduced pain (odds ratio 2.89; 95% CI [1.02;8.17]). In SOD patients, amelioration of pain in both medically and surgically treated patients is primarily associated with common bile duct dilation, rather than hepatobiliary scintigraphy excretion time or ALT.</p>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"46 4","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148197744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of a field-based submaximal stair ascent test for estimating aerobic capacity and lower-limb strength in middle-aged and older adults","authors":"Matti Hyvärinen,&nbsp;Niina Kajan,&nbsp;Eeva Kettunen,&nbsp;Ari Lehtiö,&nbsp;Jouni Kallio,&nbsp;Keegan Knittle,&nbsp;Neil Cronin,&nbsp;Laura Karavirta","doi":"10.1111/cpf.70073","DOIUrl":"10.1111/cpf.70073","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Assessing functional capacity is a key aspect of exercise testing and offers important insights into health in adult populations. However, accurate assessment often requires laboratory-based maximal tests. This pilot study investigated whether a field-based self-paced submaximal stair ascent test could feasibly assess aerobic capacity and lower-limb strength in middle-aged and older adults.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Twenty-eight participants (20 women, 8 men) aged 40 to 70 years completed maximal treadmill and isometric leg press tests to assess maximal oxygen consumption (VO₂max) and lower-limb strength, respectively. Participants also performed two separate self-paced stair ascents of four and six flights. Ascent time, mean vertical power, as well as rate of perceived exertion, absolute heart rate, and relative heart rate following the test were recorded.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Ascent time and mean vertical power were associated with VO₂max and lower-limb strength, with standardized regression coefficients ranging from −0.61 to −0.27 and from 0.41 to 0.73, respectively. However, these associations were attenuated and no longer statistically significant after controlling for age and sex. Predictive models based on the two best-performing stair ascent predictors selected by LASSO regression showed weak-to-moderate ability to predict VO₂max (<i>R</i>² = 0.21–0.52) with cross-validated model performance significantly different from zero. In contrast, the models did not significantly predict lower-limb strength.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>These preliminary findings suggest that a brief self-paced stair ascent test may offer a feasible field-based approach for estimating aerobic capacity in middle-aged and older adults. However, its predictive accuracy appears limited and should be further examined in larger samples.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"46 4","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cpf.70073","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148161982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stress native mapping does not distinguish patients with previous myocardial infarction with non-obstructive coronary arteries from healthy volunteers","authors":"Daniel F. Andersson,&nbsp;Rebecka Steffen Johansson,&nbsp;Per Tornvall,&nbsp;Peder Sörensson,&nbsp;Jannike Nickander","doi":"10.1111/cpf.70070","DOIUrl":"10.1111/cpf.70070","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Patients with myocardial infarction with non-obstructive coronary arteries (MINOCA) may be affected by coronary microvascular dysfunction with reduced stress perfusion. Changes in native T1 and T2 reflect changes in myocardial perfusion; therefore, the aim of our study was to investigate whether non-contrast, adenosine stress native T1 and T2 are affected in patients with previous suspected MINOCA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods and Results</h3>\u0000 \u0000 <p>Patients with MINOCA and a normal CMR (<i>n</i> = 15, 59 ± 7 years, 60% female) underwent 1.5T CMR together with age- and sex-matched volunteers. The protocol included native T1, native T2 and quantitative perfusion mapping, at rest and during adenosine stress. Myocardial stress perfusion was globally reduced, both transmurally (2.9 ± 0.9 vs. 3.6 ± 0.7 mL/min/g, <i>p </i>= 0.02) and in the subendocardium (2.64 ± 0.81 vs. 3.47 ± 0.78 ml/min/g, <i>p </i>= 0.008) in patients with MINOCA, with a reduced global ratio of subendocardial-to-transmural stress perfusion (0.921 ± 0.042 vs 0.957 ± 0.039, <i>p </i>= 0.021). However, there were no differences in global transmural rest native T1 or T2, stress native T1 or T2, or ΔT1- or ΔT2 values between patients and volunteers. Overall, transmural myocardial perfusion correlated with native T1 (R² = 0.27, <i>p </i>&lt; 0.001) and T2 (R² = 0.48, <i>p </i>&lt; 0.001) globally, and ΔT1 correlated with the MPR globally (R² = 0.15, <i>p </i>&lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Native T1- and T2-mapping during adenosine stress, although correlated with quantitative myocardial perfusion, are not alone sufficiently sensitive methods for distinguishing patients with MINOCA and reduced stress perfusion from healthy volunteers.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"46 4","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cpf.70070","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148161950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermographic assessment of shoulder muscles in rotator cuff injuries: Associations with pain, sleep quality, function and quality of life","authors":"Faruk Tanik,&nbsp;Derya Ozer Kaya","doi":"10.1111/cpf.70071","DOIUrl":"https://doi.org/10.1111/cpf.70071","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This exploratory study investigated associations between infrared thermography-derived skin temperatures in shoulder muscles and pain sensitivity, sleep quality, function, and quality of life in individuals with unilateral rotator cuff injuries.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this cross-sectional study, 85 participants (53 females, 32 males) with rotator cuff injuries underwent thermographic imaging of the trapezius, deltoid, biceps, brachioradialis, supraspinatus, and subscapularis muscles. Outcomes included Pressure Pain Threshold (PPT), Visual Analogue Scale (VAS) pain scores, Pittsburgh Sleep Quality Index (PSQI) scores, Disabilities of the Arm, Shoulder, and Hand (DASH) scores, and Short Form-36 (SF-36) subdomains. Correlations were analysed using Pearson or Spearman tests.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Skin temperatures of the trapezius and deltoid muscles showed positive correlations with PPT (rho = 0.235–0.422, <i>p</i> &lt; 0.05) and negative correlations with DASH scores (rho = −0.228 to −0.233, <i>p</i> &lt; 0.05). Temperatures of the deltoid, biceps, brachioradialis, and subscapularis correlated negatively with activity-related pain (rho = −0.234 to −0.301, <i>p</i> &lt; 0.05). Biceps and brachioradialis temperatures were negatively correlated with PSQI scores (rho = −0.215 to −0.269, <i>p</i> &lt; 0.05). Subscapularis temperature correlated positively with SF-36 subdomains, including Physical Role (rho = 0.308, <i>p</i> = 0.004) and General Health (rho = 0.276, <i>p</i> = 0.011). No significant correlations were observed for supraspinatus temperature or pain at rest/night.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This analysis suggests that infrared thermography reveals muscle-specific thermal patterns associated with clinical outcomes in rotator cuff injuries, supporting its potential as a non-invasive diagnostic tool for personalised assessment and management. These preliminary findings warrant confirmation in future hypothesis-driven studies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"46 4","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148129426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"46 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148082156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of exercise transcutaneous oximetry versus imaging at the buttock, thigh and calf level for the diagnosis of peripheral artery disease","authors":"Mariève Houle,&nbsp;Simon Lecoq,&nbsp;Mathieu Feuilloy,&nbsp;Jeanne Hersant,&nbsp;Samir Henni,&nbsp;Pierre Abraham","doi":"10.1111/cpf.70068","DOIUrl":"10.1111/cpf.70068","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Exercise transcutaneous oximetry (Ex-TcPO₂), through the minimal value of the “decrease from rest of oxygen pressure” (DROPmin), identifies ischemia during exercise in patients with PAD. However, its diagnostic performance at the thigh level compared to imaging modalities, has not been evaluated. The objective of this retrospective study was to perform an external validation of Ex-TcPO₂ results at the buttock and calf, a first validation of Ex-TcPO₂ at the thigh level and to determine the respective diagnostic performance of the DROPmin and DROPend (the DROP at the time of exercise cessation).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We studied 192 patients complaining of intermittent claudication. We retrieved DROPmin and DROPend values from Ex-TcPO₂ testing and the presence/absence of an ipsilateral significant stenosis ( ≥ 70%) at imaging.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The performance of Ex-TcPO₂ using DROPmin values at the buttock, thigh and calf levels were respectively fair (AUC = 0.70; 95% CI: 0.64–0.76), fair (AUC = 0.77; 95% CI: 0.72–0.83) and excellent (AUC = 0.93; 95% CI: 0.90–0.96). When using DROPend, the performance of Ex-TcPO₂ was no more significant.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion/Conclusion</h3>\u0000 \u0000 <p>This study showed that Ex-TcPO₂ has a fair to excellent accuracy for detecting the presence of at least one artery stenosis ≥70% in the lower limb according to buttock, thigh and calf area in highly selected patients. This study also highlights the importance of using the minimal value of DROPmin rather than the DROPend.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"46 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13184581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147970854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}