Clinical Physiology and Functional Imaging最新文献

{"title":"Author's reply to ‘considerations for fasting and dehydration effects on pupillary light reflex: A commentary on Adam et al.’","authors":"Mehmet Adam, Ali Osman Gündoğan, Ali Tezcan, Refik Oltulu, Selman Belviranlı, Enver Mirza, Mehmet Okka","doi":"10.1111/cpf.70018","DOIUrl":"https://doi.org/10.1111/cpf.70018","url":null,"abstract":"","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"45 4","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144264342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ventilation/perfusion SPECT in children: Feasibility, impact on clinical decision-making and interrater agreement","authors":"Lise Borgwardt,&nbsp;Mette Louise Mørk,&nbsp;Henrik Gutte,&nbsp;Anne Kiil Berthelsen,&nbsp;Robin de Nijs,&nbsp;Ronan M. G. Berg,&nbsp;Jann Mortensen","doi":"10.1111/cpf.70012","DOIUrl":"https://doi.org/10.1111/cpf.70012","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>It remains to be established whether it provides any clinical or diagnostic benefits to perform ventilation/perfusion (V/Q) scintigraphy as a single photon emission computed tomography in children. Here, we report our experience with this modality, evaluate its impact on clinical decision-making and assess its interrater agreement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>All V/Q scintigraphies performed in children over a 1-year period were identified, and patient files were reviewed. Two nuclear medicine physicians, blinded to patient data and each other's readings, interpreted all scintigraphies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 20 planar and SPECT V/Q scintigraphies were identified. In 17/20 cases (85%), the results of the scan were found to directly inform clinical decision-making. SPECT mainly ruled out the presence of ventilation and perfusion defects that were suspected on planar scintigraphy. In terms of interrater agreement, Cohen's <i>ϰ</i> coefficients for planar ventilation and perfusion scintigraphy were 0.34 and 0.38 (fair agreement), respectively, while the corresponding values for SPECT were 0.42 and 0.61 (moderate to substantial agreement).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>It is both feasible and clinically meaningful to perform V/Q SPECT in children. In this patient group, V/Q SPECT furthermore seems to have better interrater agreement than planar scintigraphy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"45 4","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cpf.70012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144220089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prior beetroot juice ingestion prevents the temporal reduction of endothelial function following acute high-intensity resistance exercise","authors":"Takuma Morishima,&nbsp;Sahiro Mizuno,&nbsp;Gaku Murakami,&nbsp;Rikako Yamazaki,&nbsp;Eisuke Ochi","doi":"10.1111/cpf.70014","DOIUrl":"https://doi.org/10.1111/cpf.70014","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Backgrounds</h3>\u0000 \u0000 <p>Nutritional strategies for preventing endothelial function impairment following high-intensity resistance exercise remain largely unknown. Considering that beetroot juice (BRJ) ingestion enhances nitric oxide levels, we aimed to evaluate whether prior BRJ ingestion would prevent endothelial function impairment following high-intensity resistance exercise.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Twelve young males underwent two experimental trials of high-intensity resistance exercise with prior: (1) placebo ingestion (PLA trial) and (2) BRJ ingestion (BRJ trial). All participants ingested 140 mL of PLA or BRJ (approximately 0.0055 or 12.8 mmol of nitrate, respectively) before the high-intensity resistance exercise (leg extension). Participants performed a resistance exercise session comprising five sets of 10 repetitions at 70% of one repetition maximum. During each intervention trial, heart rate (HR) and blood pressure were continuously measured. Brachial artery diameter, velocity, and flow-mediated dilation (FMD) were measured at pre-, 60 min after PLA or BRJ ingestion, and 10 and 60 min after the resistance exercise.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>No differences in systolic blood pressure, shear rate, blood flow, and vascular conductance in response to resistance exercise were noted between the trials (<i>p</i> &gt; 0.05). However, at post-10 min after the resistance exercise, the BRJ trial exhibited a greater brachial artery FMD than the PLA trial (<i>p</i> &lt; 0.05). Moreover, the BRJ trial had a significantly higher ΔFMD from pre- to the post-10–min period than the PLA trial (<i>p</i> &lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>BRJ ingestion prevents endothelial function impairment immediately after a high-intensity resistance exercise.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"45 4","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144197155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Absolute and relative changes in muscle thickness and muscle cross-sectional area","authors":"Samuel L. Buckner,&nbsp;Selena L. Gonzalez,&nbsp;John M. Holtje,&nbsp;Enrique N. Moreno,&nbsp;Scott J. Dankel","doi":"10.1111/cpf.70013","DOIUrl":"https://doi.org/10.1111/cpf.70013","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Changes in muscle size are often measured as a change in muscle thickness (MT) or as a change in muscle cross-sectional area (CSA). Differences in how muscles are measured is an important consideration as different absolute and relative changes in muscle size may carry different meaning.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>The purpose of the present study was to compare acute changes in MT and CSA in the rectus femoris following five sets of knee extension exercise.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Thirty-four participants visited the laboratory for one visit. Participant's dominant leg was placed into the exercise condition, and their contralateral leg was used as a non-exercise control. Ultrasound images were taken in both legs, before performing five sets of unilateral knee extension exercise in the dominant leg. Following exercise, participants had ultrasound images re-assessed. Pre and post values of MT and CSA were calculated from all images.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Muscle size increased in the exercise condition when measured as MT (mean change [95% CI] = 0.404 [−0.347 to 0.460] cm, <i>p</i> &lt; 0.00) or CSA (mean change [95% CI] = 0.734 [0.522−0.946] cm², <i>p</i> &lt; 0.001). In relative teams, MT increased by 25.5%, and the effect size of the change was 2.49. For CSA, the relative change was 37.3% and the effect size of the change was 1.20.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The relative change in MT following five sets of knee extension exercise was smaller than the relative change in CSA; however, the effect was larger, suggesting that the smaller relative change may have been easier to detect.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"45 4","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144197154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Considerations for fasting and dehydration effects on pupillary light reflex: A commentary on Adam et al. (2025)","authors":"Kong Siang Syuan,&nbsp;Lien-Chung Wei","doi":"10.1111/cpf.70015","DOIUrl":"https://doi.org/10.1111/cpf.70015","url":null,"abstract":"","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"45 4","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiological alterations around the menopause transition—A 2-year follow-up in PRE, PERI, and POST menopause females","authors":"Paul A. Baker,&nbsp;Sam R. Moore,&nbsp;Abbie E. Smith-Ryan","doi":"10.1111/cpf.70011","DOIUrl":"https://doi.org/10.1111/cpf.70011","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The menopause transition is a critical period marked by significant physiological adaptations. Data on the dynamic changes in body composition and metabolism during this transition are limited. The purpose was to determine body composition and metabolic changes over a 2-year follow-up in a cross-sectional sample of premenopausal (PRE), perimenopausal (PERI), and postmenopausal (POST) females.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Twenty-three females who previously participated in a cross-sectional study returned for a 2-year follow-up visit were classified as PRE, PERI, or POST based on menstrual history and a Menopause Health Questionnaire. Muscle size [muscle cross-sectional area (mCSA)] and muscle quality [echo intensity, (EI)] were evaluated in the vastus lateralis with ultrasound. Bone mass and body composition were assessed using dual-energy X-ray absorptiometry, and metabolic flexibility through submax exercise with indirect calorimetry.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>At the 2-year follow-up, POST females had an increase in EI (change: 26.93 ± 12.82 a.u., group×time p-adjusted = 0.001) with no change in mCSA (change: −2.03 ± 2.40 cm², group×time <i>p</i> = 0.980). PERI compared to PRE females had lower total bone mass (group×time p-adjusted = 0.029) with an even lower bone mass in POST compared to PERI females (group×time p-adjusted = 0.023). No differences in metabolic flexibility at any exercise intensity were observed between groups over time (group×time <i>p</i> = ≥ 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study highlights a decline in muscle quality and total bone mass despite stable muscle size, emphasizing the need for targeted exercise and nutrition interventions to support muscle and bone health in females around the menopause transition.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"45 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143939218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of 7-day dietary supplementation with grape seed extract on cardiac autonomic and hemodynamic responses in elevated and stage 1 hypertension","authors":"Albert Lira,&nbsp;William Boyer,&nbsp;Trevor Gillum,&nbsp;Sean Sullivan,&nbsp;Jong-Kyung Kim","doi":"10.1111/cpf.70010","DOIUrl":"https://doi.org/10.1111/cpf.70010","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Backgrounds</h3>\u0000 \u0000 <p>Evidence indicated that an increase in nitric oxide (NO) bioavailability via dietary supplementation decreased sympathetic output. Grape seed extract (GSE) supplement has been known to increase NO production and improve endothelial function in individuals with elevated and stage 1 hypertension (ES1H), but no studies have assessed the effects of this extract on autonomic balance. Accordingly, the aim of the study was to investigate the effect of 7 days of dietary GSE supplementation on cardiac autonomic and hemodynamic responses.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Ten males were recruited in this study. Each subject received GSE or placebo supplementation with a 1-week wash-out period. In a double-blinded, cross-over design, hemodynamic responses (heart rate (HR), stroke volume (SV), cardiac output (CO), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean atrial pressure (MAP)), heart rate variability (HRV), and cold pressor test (CPT) were compared before and after either GSE or placebo supplementation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Our results indicated that GSE decreased resting DBP (75 ± 2 vs. 71 ± 3) and MAP (91 ± 2 vs. 88 ± 3) compared to the placebo (DBP:71 ± 3 vs. 74 ± 3; MAP: 89 ± 2 vs. 90 ± 2). However, MAP responses to CPT had no difference between post-PL and post-GSE supplementation when expressed as absolute increases (PL, Δ10.3 ± 1 mmHg, GSE, Δ9.1 ± 1 mmHg). There were no differences on the HR, SV, CO, SBP, and HRV between placebo and GSE treatments.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Our study suggests that GSE can be used as a dietary nutraceutical capable of reducing blood pressure and the risk of ES1H development. The reduction of blood pressure occurs via peripheral vasodilation, not associated with cardiac autonomic reactivity.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"45 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cpf.70010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143919659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic value of combined heart and lung ultrasound in emergency department patients with dyspnea","authors":"Anna Bjällmark,&nbsp;Gustaf Hummel,&nbsp;Kambiz Shahgaldi","doi":"10.1111/cpf.70009","DOIUrl":"https://doi.org/10.1111/cpf.70009","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Acute dyspnea in emergency departments (ED) requires prompt and accurate diagnosis due to its high mortality and readmission rates. Conventional diagnostic methods are resource-intensive and time-consuming. This study aimed to evaluate the diagnostic accuracy and time to diagnosis of combined heart and lung ultrasound (HeaLus) compared to standard emergency department evaluation in patients presenting with dyspnea.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A prospective study was conducted in a cohort of 61 patients at the ED of Danderyd Hospital, Sweden. HeaLus examinations were performed alongside routine investigations. Diagnostic performance of HeaLus and ED evaluation was assessed for accuracy, sensitivity, specificity, positive predictive value, and negative predictive value, and agreement using Kappa index. Median time to diagnostics was compared between HeaLus and ED evaluation using Mann-Whitney U-test.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Heart failure was the most common diagnosis (20%) among patients presenting with dyspnea. The diagnostic accuracy, sensitivity, specificity, positive predictive value, and negative predictive value were 95% (95% CI: [87%, 98%]), 98% (95% CI: [88%, 100%]), 90% (95% CI: [69%, 97%]), 95% (95% CI: [85%, 99%]), and 94% (95% CI: [74%, 99%]), respectively. The agreement between HeaLus and ED diagnoses was 0.88. Time to diagnosis was significantly reduced with HeaLus (21 min vs. 3 h and 28 min).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>HeaLus offers rapid and accurate assessment of dyspnea. These results suggest that HeaLus could be valuable in optimizing patient management, particularly in settings with limited resources and long ED wait times.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"45 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cpf.70009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143840803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Agreement of concomitant cardiac output measurement by thoracic bio-impedance and inert gas rebreathing in healthy subjects","authors":"Laura Filaire,&nbsp;Hélène Perrault,&nbsp;Claire Dauphin,&nbsp;Aurélie Chalard,&nbsp;Bruno Pereira,&nbsp;Frederic Costes,&nbsp;Ruddy Richard","doi":"10.1111/cpf.70005","DOIUrl":"https://doi.org/10.1111/cpf.70005","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>Inasmuch as they are deemed valid, noninvasive measurement of cardiac output techniques present advantages of ease and safety for use in humans. Few studies have compared the use of thoracic bioimpedance and inert gas rebreathing techniques for cardiac output (CO) assessment at rest and exercise. This manuscript reports on differences between Physioflow® and Innocor® CO measurements at rest and during cycling in a population of healthy subjects.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Fifty healthy subjects (52 ± 16 years) underwent an incremental cycle exercise testing (IET) during which standardized Physioflow® and Innocor® CO assessments were achieved. Measurements were completed in a subgroup of twelve subjects during two constant-load 10-min cycling bouts at moderate and high intensities.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Mean difference between Physioflow® and Innocor® was of 0.002 ± 0.98 l/min at rest and 0.38 ± 1.31 l/min during IET without statistical difference. Correlation coefficient values were higher for exercise (<i>r</i> = 0.83) than resting (<i>r</i> = 0.40) measurements. Good reproducibility of the two devices was observed on different graded exercises with intraindividual variability lower than 6%, except for rest Innocor® CO measurements (CV = 18%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Physioflow® and Innocor® can be easily used concomitantly for noninvasive measurement of CO. Despite finding a strong agreement between techniques for exercise CO, results should not be interpreted as being interchangeable as values are derived from different flow measurements: systemic blood flow for Physioflow® and pulmonary blood flow for Innocor®. However, the concomitant use of both techniques could be of value in clinical setting for noninvasive intrathoracic shunt quantification.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"45 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cpf.70005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ventilation/perfusion scintigraphy in patients with pulmonary vascular anomaly","authors":"Hamdi Afşin,&nbsp;Emine Afşin","doi":"10.1111/cpf.70008","DOIUrl":"10.1111/cpf.70008","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Although ventilation/perfusion (V/Q) scintigraphy is frequently used in the diagnosis of acute or chronic pulmonary embolism (PE), it also plays a significant role in diagnosing pulmonary vascular diseases. Additionally, in the presence of a mismatch defect on V/Q scintigraphy, pulmonary vascular anomalies should be considered as a possible alternative to PE. For this reason, we aimed to present three cases with Swyer–James–MacLeod syndrome (SJMS), one of which was also complicated by PE, and one case with pulmonary artery hypoplasia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>Case 1: PE was diagnosed by V/Q scintigraphy in a patient with known SJMS. Case 2: SJMS was diagnosed by thoracic computed tomography (CT), flexible optical bronchoscopy (FOB) and V/Q scintigraphy. Case 3: V/Q scintigraphy revealed pulmonary artery hypoplasia in the differential diagnosis of PE when evaluated together with FOB and thoracic CT. Case 4: Diagnosed as SJMS by Thorax CT and V/Q scintigraphy in the presence of chronic lung disease.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>V/Q scintigraphy is also used in the diagnosis of congenital/hereditary vascular and airway diseases. Thoracic CT should be performed together with evaluation to reach the diagnosis in this group of patients. In cases with mismatch defects, vascular anomalies should also be considered in the differential diagnosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":"45 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}