Clinical Otolaryngology最新文献

{"title":"Correction to \"The Survival Outcomes of Prophylactic Lateral Neck Dissection for Medullary Thyroid Carcinoma, a Retrospective Cohort Study\".","authors":"","doi":"10.1111/coa.70149","DOIUrl":"10.1111/coa.70149","url":null,"abstract":"","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":" ","pages":"977"},"PeriodicalIF":1.9,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148599700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arytenoid Cartilage Ossification in Early Glottic Carcinoma and Its Association With Tumour Stage and Treatment Outcome: A Retrospective Analysis.","authors":"Liron Malka, Yael Shapira-Galitz, Meital Adi, Oded Cohen, Hagit Shoffel-Havakuk, Inbar Riba-Roitblat, Yonatan Lahav","doi":"10.1111/coa.70135","DOIUrl":"10.1111/coa.70135","url":null,"abstract":"","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":" ","pages":"966-970"},"PeriodicalIF":1.9,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148359800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safe Introduction of a Transoral Endoscopic Vestibular Thyroidectomy Programme Within UK Governance Frameworks.","authors":"Maria Kiakou, Enyinnaya Ofo, Zoi Zachou, Georgios Oikonomou","doi":"10.1111/coa.70144","DOIUrl":"10.1111/coa.70144","url":null,"abstract":"","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":" ","pages":"975-976"},"PeriodicalIF":1.9,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148419416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Manuka Honey Sinus Irrigation Versus Systemic Itraconazole in Allergic Fungal Rhinosinusitis: Randomised Clinical Trial for Efficacy and Safety.","authors":"Khalaf Hamead, Mostafa Ismail, Abdelrahim A Abdelkarim, Abdelhakim Atef Abdelhakim, Khaled Mohamed Abdelzaher","doi":"10.1111/coa.70161","DOIUrl":"10.1111/coa.70161","url":null,"abstract":"<p><strong>Background: </strong>Allergic fungal rhinosinusitis (AFRS) is a persistent sinus condition caused by fungal allergies. Endoscopic sinus surgery (ESS) and postoperative systematic and local medical therapies are the most common treatment protocols. Although oral antifungals such as itraconazole are frequently utilised postoperatively, there is increasing interest in alternate therapies that exhibit fewer systemic adverse effects. Manuka honey, recognised for its powerful antibacterial, antifungal and anti-inflammatory characteristics, is a promising alternative. The aim of this study was to assess the efficacy of Manuka honey sinus irrigation in comparison with oral itraconazole for the postoperative management of AFRS.</p><p><strong>Methods: </strong>Thirty patients diagnosed with AFRS were recruited for the current randomised clinical trial after ESS. Patients in the two groups randomly received either oral itraconazole (Group A) or Manuka honey sinus irrigation (Group B) for 6 weeks postoperatively. Both cohorts were monitored for 6 months postoperatively.</p><p><strong>Results: </strong>Lund-Kennedy endoscopic scores, total IgE levels and SNOT-22 scores were significantly improved in Group B after Manuka honey sinus irrigation. Both groups had similar Lund-Mackay radiological scores and numbers of postoperative sinus infections during the follow-up period.</p><p><strong>Conclusions: </strong>Postoperative Manuka honey sinus irrigation is more effective than oral itraconazole for reducing symptoms and preventing the recurrence of AFRS. It is considered a promising therapeutic alternative in the postoperative management of AFRS.</p>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":" ","pages":"960-965"},"PeriodicalIF":1.9,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13631801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-Operative Polysomnographic Changes in Patients With Beckwith-Wiedemann Syndrome Following Surgical Intervention for Obstructive Sleep Apnoea.","authors":"Regan C Manayan, Thomas C Flowers, Mele Mafi, Gi Soo Lee","doi":"10.1111/coa.70151","DOIUrl":"10.1111/coa.70151","url":null,"abstract":"","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":" ","pages":"971-974"},"PeriodicalIF":1.9,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Cross-Sectional Study of Patient Views on Acceptability of Olfactory Implants.","authors":"Gabija Klyvyte, William Ansley, Mehmet Ergisi, Lois Camp, Prajakta Choudari, Natalia Glibbery, Mohammed Jawad, Tharsika Myuran, Duncan Boak, Carl Philpott","doi":"10.1111/coa.70182","DOIUrl":"https://doi.org/10.1111/coa.70182","url":null,"abstract":"<p><strong>Objectives: </strong>Unlike other chronic conditions, effective therapies for smell and taste disorders (SATDs) remain scarce. Olfactory implants are an emerging area of therapy aimed at restoring the sense of smell through electrical stimulation of the olfactory pathway. This survey aimed to assess patient opinions and the acceptability of olfactory implants, including willingness to undergo surgery, as well as factors influencing their decision-making process.</p><p><strong>Design and setting: </strong>This was a cross-sectional survey consisting of two online questionnaires circulated via the charity SmellTaste, exploring features and impacts of SATDs, and opinions surrounding olfactory implants in those formally diagnosed or self-identifying with SATDs.</p><p><strong>Results: </strong>A total of 410 participants completed the primary questionnaire assessing general demographics and olfactory experiences. A further 47 participants completed the second, more in-depth questionnaire about the perceptions on olfactory implants. Across both questionnaires, more females responded than males-a trend seen throughout research on SATDs. An overwhelming majority of participants would be willing to wear a non-implantable device to help detect odour quantity and quality, especially if used to detect dangers such as gas and fires. Opinions on surgically implantable devices varied more. Most patients were amenable prior to any mention of risks, but further probing revealed understanding risks and success rates of any procedure were key to guiding patient decisions.</p><p><strong>Conclusion: </strong>There are patients with olfactory loss who are willing to use an olfactory implant; therefore, more extensive research into the safety, viability and efficacy of olfactory implants is needed.</p>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Bleeding Rates After Tonsil Surgery in Denmark and Opportunities for Quality Improvement.","authors":"Martin Mølhave, Nina M Lyhne, Susanne H Nielsen, Pernille Hahn, Jesper K Holm, Therese Ovesen","doi":"10.1111/coa.70184","DOIUrl":"https://doi.org/10.1111/coa.70184","url":null,"abstract":"<p><strong>Objectives: </strong>To examine postoperative bleeding rates and associated patient and surgical factors after tonsil surgery in Denmark and identify targets for quality improvement.</p><p><strong>Design: </strong>Multicentre cohort study using prospectively collected registry data.</p><p><strong>Setting: </strong>Five Danish ENT departments contributing to the Danish Tonsil Database, 2018-2024.</p><p><strong>Participants: </strong>Children, adolescents and adults undergoing tonsillectomy, adenotonsillectomy, tonsillotomy, adenotonsillotomy or acute tonsillectomy for benign indications.</p><p><strong>Main outcome measures: </strong>Clinically confirmed postoperative bleeding within 30 days. Modified Poisson regression with robust standard errors estimated adjusted relative risks (RRs).</p><p><strong>Results: </strong>Among 6145 procedures, postoperative bleeding occurred after 14% of tonsillectomies, 9.9% of adenotonsillectomies, 10% of acute tonsillectomies, 1.7% of tonsillotomies and 2.6% of adenotonsillotomies. Among bleeding events, 51% required general anaesthesia, 32% local anaesthesia and 17% resolved spontaneously. After tonsillectomy, male sex (adjusted RR 1.69, 95% CI 1.44-2.00) and resident surgery (adjusted RR 1.25, 95% CI 1.04-1.51) were associated with higher risk, while patients aged < 12 years (adjusted RR 0.53, 95% CI 0.37-0.74) and 12-17 years (adjusted RR 0.57, 95% CI 0.43-0.76) had lower risk than adults. Cold dissection with cold haemostasis tonsillectomy had the lowest crude bleeding rate (9.8%), but operative technique was not independently associated with bleeding after adjustment. No deaths occurred.</p><p><strong>Conclusions: </strong>Bleeding rates after tonsillectomy were higher than those reported in several international cohorts, while rates after tonsillotomy were low. Cold dissection with cold haemostasis tonsillectomy had the lowest observed rate, although adjusted analyses were not statistically significant. These findings support structured quality-improvement work and continued monitoring.</p>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unsuccessful Healing of Tympanic Membrane Perforations Following Myringoplasty-A Nationwide Retrospective Study.","authors":"Elnaz Sepehri, Julia Arebro, Eva Westman, Per Olof Eriksson","doi":"10.1111/coa.70176","DOIUrl":"https://doi.org/10.1111/coa.70176","url":null,"abstract":"<p><strong>Introduction: </strong>Risk factors for unsuccessful healing of a tympanic membrane perforation following myringoplasty lack consensus. Large cohort studies are missing.</p><p><strong>Methods: </strong>Data were collected for myringoplasties (with/without concomitant ossiculoplasty) performed the years 2014-2019 with a follow-up visit using the Swedish Quality Register for Ear Surgery (SwedEar). Risk factors for unsuccessful surgical outcome, defined as non-healed tympanic membrane at follow-up, were calculated using logistic regression.</p><p><strong>Results: </strong>The study population included 3622 cases and 12.8% had a non-healed tympanic membrane at follow-up. The most commonly used graft material was fascia, used in 94.6% of the cases. Of the analysed variables, prior ear surgery (adjusted (a)OR 1.43, p = 0.005), age younger than 8 years (aOR 1.73, p = 0.015), a postoperative infection within 6 weeks after surgery (aOR 1.92, p < 0.001) and the surgical aim of achieving a dry/infection free ear (aOR 1.53, p = 0.045) were predictors for unsuccessful healing. For simultaneous ossiculoplasty at surgery, there was a significantly higher chance of having a healed tympanic membrane (aOR 1.49, p = 0.016). For other variables such as gender, operated side, season, graft material, perioperative antibiotics and infection free status at surgery, there was no significant effect on tympanic membrane healing.</p><p><strong>Conclusion: </strong>The present evaluation of the surgical results in SwedEar constitutes one of the largest studies on myringoplasty outcome. The results showed that the age of the patient, surgical aim, prior ear surgery and postoperative infection constituted risk factors for unsuccessful healing after myringoplasty. Surprisingly, ears requiring a concomitant ossiculoplasty had a higher healing rate.</p>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of ENT Referral and Microlaryngobronchoscopy Findings in Children With Recurrent Croup: A 10-Year Cohort Study.","authors":"Noon Nassr, Jonathan Wareing, Victoria Ward","doi":"10.1111/coa.70178","DOIUrl":"https://doi.org/10.1111/coa.70178","url":null,"abstract":"<p><strong>Objective: </strong>To determine predictors of ENT referral and microlaryngobronchoscopy (MLB) findings in children with recurrent croup.</p><p><strong>Design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>Large district general NHS trust (2013-2023).</p><p><strong>Participants: </strong>Children < 18 years with ≥ 2 croup episodes in 12 months or a clinician diagnosis of recurrent croup.</p><p><strong>Main outcome measures: </strong>ENT referral, MLB performance and abnormal MLB findings.</p><p><strong>Results: </strong>128 children met recurrent croup criteria (median age 13.5 months, median 5 episodes). Sixty-two (48%) were referred to ENT, of which 34 (55%) underwent MLB. Thirteen (38%) MLBs were normal. Abnormalities included subglottic stenosis (n = 5), dynamic airway collapse (n = 4), vocal-cord pathology (n = 3), non-specific inflammatory/irritative change (n = 3) and subglottic lesions (n = 5), with the latter requiring surgical excision. Referred children were younger (median 12 vs. 17 months, p = 0.038) and had more episodes (median 5.5 vs. 4.0, p = 0.013). ENT referral correlated with ENT-related conditions (26%, p < 0.001), gastro-oesophageal reflux (24%, p = 0.021) and recurrent viral infections (47%, p = 0.022). MLB was more common with ENT-related conditions (38%, p < 0.001) and reflux (32%, p = 0.003). After adjustment, only episode count predicted ENT referral (aOR 1.09 per episode, 95% CI: 1.01-1.19), no factor predicted MLB or abnormal findings.</p><p><strong>Conclusions: </strong>ENT review is warranted for recurrent croup, whereas MLB should be reserved for children with red-flag features suggesting significant airway pathology. Although most scoped children had normal or conservatively managed findings, a meaningful minority had clinically important abnormalities, including subglottic lesions requiring surgical intervention. Conventional risk factors offer little predictive value, supporting prospective multi-centre studies to refine risk-stratification.</p>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolution of Bacterial Yield and Antimicrobial Resistance in Chronic Rhinosinusitis Patients in a Dedicated Sinus Centre.","authors":"Timoleon Siempis, Zhu Yeap, Shifa Ali, Carl M Philpott","doi":"10.1111/coa.70172","DOIUrl":"https://doi.org/10.1111/coa.70172","url":null,"abstract":"<p><strong>Background: </strong>Antibiotics are frequently prescribed for acute exacerbations of chronic rhinosinusitis (CRS). However, antimicrobial resistance presents a challenge for the ongoing and future management of CRS patients.</p><p><strong>Objective: </strong>This study aims to examine the current and past microbiological yield and antimicrobial resistance profile in a tertiary sinus centre.</p><p><strong>Methodology: </strong>A retrospective results review for the calendar years from 2015 to 2018 and 2019 to 2024 was conducted on all CRS patients who had sinonasal microbiological samples taken during their outpatient visits with a history of previous endoscopic sinus surgery (ESS).</p><p><strong>Results: </strong>A total of 706 cultures were analysed from 338 patients. Clinically significant organisms were identified in 60.0% of cases in 2015-2018 and 71.9% of cases in 2019-2024 (p = 0.003). Whilst Staphylococcus aureus remained the predominant isolate in both groups, Gram-negative organisms rose significantly (32.9%-46.5%, p = 0.004), particularly non-Pseudomonas and Enterobacteriaceae species. Interestingly, classical acute bacterial rhinosinusitis pathogens (Staphylococcus pneumoniae, Moraxella catarrhalis, Haemophilus influenzae) were detected in only 28.0% and 23.8% of cases in the respective study periods. Resistance to clarithromycin in S. aureus isolates increased significantly from 12.1% to 27.5% (p = 0.0008), whilst resistance to doxycycline and amoxicillin also rose, though these changes were not statistically significant. Resistance to co-amoxiclav increased from 0.3% to 3.2% in 2019-2024. (p = 0.0276).</p><p><strong>Conclusion: </strong>There has been an increase in the incidence of Gram-negative bacteria as well as antibiotic resistance in CRS sinonasal cultures. These findings emphasise the importance of endoscopically guided cultures and culture-directed antibiotic therapy when managing postoperative CRS exacerbations.</p>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}