Cecilia Rosso, Federica Turati, Alberto Maria Saibene, Elvira Verduci, Giuseppe Banderali, Monica Ferraroni, Giovanni Felisati, Carlotta Pipolo
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引用次数: 0
Abstract
Background: Paediatric airway diseases such as asthma, allergies, rhinitis, upper respiratory tract infections and acute otitis media are major health challenges for children globally. The prevalence of these conditions has been increasing, impacting children's quality of life, educational attainment and imposing a substantial economic burden.
Objectives: This longitudinal prospective study investigated the prevalence rates and environmental links associated with paediatric airway diseases in the first 3 years of life in 241 newborns, with the goal of contributing to early detection, prevention and management strategies.
Methods: Structured questionnaires were administered to parents at birth, 1 year and 3 years of age. Data on socioeconomic factors, pregnancy and delivery characteristics, parental smoking, breastfeeding, childcare attendance and children's health history were collected. Skin prick tests were conducted in year 3 to assess allergic sensitisation.
Results: Two hundred seven patients completed three-year follow-up. Factors such as having siblings, exclusive breastfeeding and attending kindergarten were associated with increased risks of certain diseases at 1 and 3 years. Smoking exposure appeared protective against wheezing in the first year. Breastfeeding showed mixed results, with protective effects against URTIs at 1 year but a potential risk factor for asthma at 1 year. Kindergarten attendance was associated with increased risks of URTIs and AOM at 3 years but appeared protective against inhalant allergies.
Conclusion: The study highlighted the complex interplay of various factors in the development of paediatric airway diseases. Further research is needed to refine our understanding of these factors and their impact on paediatric diseases.
期刊介绍：
Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with:
current otorhinolaryngological practice
audiology, otology, balance, rhinology, larynx, voice and paediatric ORL
head and neck oncology
head and neck plastic and reconstructive surgery
continuing medical education and ORL training
The emphasis is on high quality new work in the clinical field and on fresh, original research.
Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject.
• Negative/null results
In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.
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