Ja-Yoon Kim, Hyung-Ju Cho, Chang-Hoon Kim, Min-Seok Rha
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引用次数: 0
Abstract
Objectives: This study aimed to evaluate the olfactory and gustatory functions of patients with nasal septal deviation (NSD) and identify the factors associated with olfactory loss (OL) and gustatory loss (GL).
Design and setting: Retrospective data analysis of cohort group.
Participants: Two-hundred fourteen adult patients with NSD at a tertiary hospital.
Main outcome measures: Olfactory and gustatory functions were assessed using the psychophysical olfactory and gustatory function tests. The association of various demographic and clinical factors, including age, sex, NSD type, allergic sensitization status, presence of concha bullosa (CB), total serum immunoglobulin E (IgE) level, blood eosinophil count, and acoustic rhinometry parameters, with OL and GL was analysed.
Results: Among the patients, 20.6% (44/214) and 16.4% (35/213) had OL and GL, respectively. Patients with CB showed a significantly lower threshold, discrimination, and identification (TDI) score than those without CB (p = 0.012). Conversely, the TDI score did not differ according to age group, sex, NSD type, or allergic sensitization status. Blood eosinophil count was inversely correlated with the TDI score (p = 0.003), whereas nasal cavity volume, minimal cross-sectional area, and serum IgE level were not correlated with the TDI score. In the multivariable analysis, the presence of CB (p = 0.029, odds ratio [OR] = 2.281) and a blood eosinophil count ≥ 190 (p = 0.030, OR = 2.155) were identified as significant factors associated with OL. No factors were significantly associated with GL.
Conclusion: The presence of CB and a high blood eosinophil count are significant predictors of OL in patients with NSD.
期刊介绍：
Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with:
current otorhinolaryngological practice
audiology, otology, balance, rhinology, larynx, voice and paediatric ORL
head and neck oncology
head and neck plastic and reconstructive surgery
continuing medical education and ORL training
The emphasis is on high quality new work in the clinical field and on fresh, original research.
Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject.
• Negative/null results
In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.
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