Zachary J. E. Zytner, Joshua R. Stanley, Preeti Grewal, Elizabeth Dettmer, Alene Toulany, Mark R. Palmert, Julia C. Sorbara
{"title":"Gender diversity among adolescents with obesity in a weight management programme","authors":"Zachary J. E. Zytner, Joshua R. Stanley, Preeti Grewal, Elizabeth Dettmer, Alene Toulany, Mark R. Palmert, Julia C. Sorbara","doi":"10.1111/cob.12664","DOIUrl":"10.1111/cob.12664","url":null,"abstract":"<p>Gender dysphoria (GD) and obesity share commonalities, including associations with mental health comorbidities, disordered eating, body dissatisfaction and may intensify with physical and developmental changes during adolescence. While associations of obesity and gender diversity have been identified, rates of gender diversity among adolescents with obesity remain unclear. The aim was to examine gender diversity among adolescents with obesity in a weight management programme. A single-centre cross-sectional questionnaire study was conducted. Eligible adolescents received the Gender Identity/GD Questionnaire for Adolescents and Adults (GIDYQ-AA), a validated instrument measuring gender diversity and GD. Gender identities, sexual orientations, questionnaire scores, and frequency of GD (GIDYQ-AA score <3) were determined. The relationship of GIDYQ-AA scores and BMI Z-score (BMIz) was assessed. Of 72 consenting youth, 29 assigned females (AF) and 17 assigned males (AM) completed GIDYQ-AA and demographic questions. Seventeen (59%) AF reported non-heterosexual orientations, and 6 (21%) reported non-cisgender identities. One (6%) AM reported non-cisgender identity. Two (4%) AF individuals had GD based on GIDYQ-AA scores. GIDYQ-AA scores did not correlate with BMIz. In conclusion, adolescents with obesity, particularly AF with non-heterosexual orientation, reported high rates of non-cisgender identity and GD. Routine screening for gender-related concerns in weight management settings may be warranted.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.12664","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140702722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Viviana Bauman, Taylor N. Swanson, Abraham J. Eastman, Kathryn M. Ross, Michael G. Perri
{"title":"Perceptions of an acceptance-based weight management treatment among adults living in rural areas","authors":"Viviana Bauman, Taylor N. Swanson, Abraham J. Eastman, Kathryn M. Ross, Michael G. Perri","doi":"10.1111/cob.12662","DOIUrl":"10.1111/cob.12662","url":null,"abstract":"<div>\u0000 \u0000 <p>Obesity and obesity-related comorbidities disproportionately affect rural communities. Research has emerged in support of a novel acceptance-based behavioural weight management treatment (ABT) that integrates the principles and procedures of acceptance-commitment therapy (ACT) with traditional components of standard behavioural treatment (SBT). The current study assessed the perceptions of community stakeholders in rural areas to session materials of a commercially available ABT program. Surveys and focus groups were used to solicit feedback from three former interventionists with experience delivering SBTs in rural counties and from 17 former participants in these programs. Qualitative responses encompassed four overarching themes: (1) recommendations to support participant engagement, (2) comments about preferences for specific ABT and SBT strategies, (3) concerns about specific aspects of treatment delivery, and (4) requests for aesthetic changes to session materials to enhance clarity and engagement. Overall, participants viewed ABT materials and concepts favourably but believed it would be important to begin the intervention with rapport building and training in traditional SBT strategies prior to delving into ACT strategies. Future studies should investigate the efficacy of ABT for weight loss in adults with obesity living in rural communities and continue to solicit feedback from rural community stakeholders.</p>\u0000 </div>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140712087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peter Kühnen, Jesús Argente, Karine Clément, Hélène Dollfus, Béatrice Dubern, Sadaf Farooqi, Corjan de Groot, Annette Grüters, Jens-Christian Holm, Mark Hopkins, Lotte Kleinendorst, Antje Körner, David Meeker, Mikael Rydén, Julia von Schnurbein, Matthias Tschöp, Giles S. H. Yeo, Stefanie Zorn, Martin Wabitsch
{"title":"IMPROVE 2022 International Meeting on Pathway-Related Obesity: Vision of Excellence","authors":"Peter Kühnen, Jesús Argente, Karine Clément, Hélène Dollfus, Béatrice Dubern, Sadaf Farooqi, Corjan de Groot, Annette Grüters, Jens-Christian Holm, Mark Hopkins, Lotte Kleinendorst, Antje Körner, David Meeker, Mikael Rydén, Julia von Schnurbein, Matthias Tschöp, Giles S. H. Yeo, Stefanie Zorn, Martin Wabitsch","doi":"10.1111/cob.12659","DOIUrl":"10.1111/cob.12659","url":null,"abstract":"<p>Nearly 90 clinicians and researchers from around the world attended the first IMPROVE 2022 International Meeting on Pathway-Related Obesity. Delegates attended in person or online from across Europe, Argentina and Israel to hear the latest scientific and clinical developments in hyperphagia and severe, early-onset obesity, and set out a vision of excellence for the future for improving the diagnosis, treatment, and care of patients with melanocortin-4 receptor (MC4R) pathway-related obesity. The meeting co-chair Peter Kühnen, Charité Universitätsmedizin Berlin, Germany, indicated that change was needed with the rapidly increasing prevalence of obesity and the associated complications to improve the understanding of the underlying mechanisms and acknowledge that monogenic forms of obesity can play an important role, providing insights that can be applied to a wider group of patients with obesity. World-leading experts presented the latest research and led discussions on the underlying science of obesity, diagnosis (including clinical and genetic approaches such as the role of defective MC4R signalling), and emerging clinical data and research with targeted pharmacological approaches. The aim of the meeting was to agree on the questions that needed to be addressed in future research and to ensure that optimised diagnostic work-up was used with new genetic testing tools becoming available. This should aid the planning of new evidence-based treatment strategies for the future, as explained by co-chair Martin Wabitsch, Ulm University Medical Center, Germany.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 3","pages":""},"PeriodicalIF":3.3,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.12659","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140712737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elliot T. Varney, Seth Lirette, Peter T. Katzmarzyk, Frank Greenway, Candace M. Howard
{"title":"Computed Tomography and Dual-Energy X-Ray Asorptiometry body composition parameter harmonisation to universalise adipose tissue measurements in a population-based cross-sectional study","authors":"Elliot T. Varney, Seth Lirette, Peter T. Katzmarzyk, Frank Greenway, Candace M. Howard","doi":"10.1111/cob.12660","DOIUrl":"10.1111/cob.12660","url":null,"abstract":"<div>\u0000 \u0000 <p>To harmonise computed tomography (CT) and dual-energy x-ray absorptiometry (DXA) body composition measurements allowing easy conversion in longitudinal assessments and across cohorts to assess cardiometabolic risk and disease. Retrospective cross-sectional observational study from 1996 to 2008 included participants in the Pennington Center Longitudinal Study (PCLS) (<i>N</i> = 1967; 571 African American/1396 White). Anthropometrics, whole-body DXA and abdominal CT images were obtained. Multi-layer segmentation techniques (Analyze; Rochester, MN) quantified visceral adipose tissue (VAT). Clinical biomarkers were obtained from routine blood samples. Linear models were used to predict CT-VAT from DXA-VAT and examine the effects of traditional biomarkers on cross-sectional-VAT. Predicted CT-VAT was highly associated with measured CT-VAT using ordinary least square linear regression analysis and random forest models (<i>R</i><sup>2</sup> = 0.84; 0.94, respectively, <i>p</i> < .0001). Model stratification effects showed low variability between races and sexes. Overall, associations between measured CT-VAT and DXA-predicted CT-VAT were good (<i>R</i><sup>2</sup> > 0.7) or excellent (<i>R</i><sup>2</sup> > 0.8) and improved for all stratification groups except African American men using random forest models. The clinical effects on measured CT-VAT and DXA-VAT showed no significant clinical difference in the measured adipose tissue areas (mean difference = 0.22 cm<sup>2</sup>). Random forest modelling seamlessly predicts CT-VAT from measured DXA-VAT to a degree of accuracy that falls within the bounds of universally accepted standard error.</p>\u0000 </div>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140713068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lotte Kleinendorst, Ozair Abawi, Niels Vos, Eline S. van der Valk, Saskia M. Maas, Angela T. Morgan, Michael S. Hildebrand, Jorge D. Da Silva, Ralph J. Florijn, Peter Lauffer, Jenny A. Visser, Elisabeth F. C. van Rossum, Erica L. T. van den Akker, Mieke M. van Haelst
{"title":"GNB1 and obesity: Evidence for a correlation between haploinsufficiency and syndromic obesity","authors":"Lotte Kleinendorst, Ozair Abawi, Niels Vos, Eline S. van der Valk, Saskia M. Maas, Angela T. Morgan, Michael S. Hildebrand, Jorge D. Da Silva, Ralph J. Florijn, Peter Lauffer, Jenny A. Visser, Elisabeth F. C. van Rossum, Erica L. T. van den Akker, Mieke M. van Haelst","doi":"10.1111/cob.12661","DOIUrl":"10.1111/cob.12661","url":null,"abstract":"<p>Most patients with <i>GNB1</i> encephalopathy have developmental delay and/or intellectual disability, brain anomalies and seizures. Recently, two cases with <i>GNB1</i> encephalopathy caused by haploinsufficiency have been reported that also show a Prader–Willi-like phenotype of childhood hypotonia and severe obesity. Here we present three new cases from our expert centre for genetic obesity in which <i>GNB1</i> truncating and splice variants, probably leading to haploinsufficiency, were identified. They all have obesity, hyperphagia and intellectual deficit. The clinical cases and their weight courses are presented, together with a review of all 68 published cases with <i>GNB1</i> encephalopathy. Information on weight was not mentioned in most of these articles, so we contacted authors for additional clinical information on weight status and hyperphagia. Of the 42 patients whose weight status we could determine, obesity was present in 8 patients (19%). Obesity is significantly over-represented in the group with truncating and splicing variants. In this group, we see an obesity prevalence of 75%. Since <i>GNB1</i> has been linked to several key genes in the hypothalamic leptin-melanocortin pathway, which regulates satiety and energy expenditure, our data support the potential association between <i>GNB1</i> haploinsufficiency and genetic obesity. We also suggest <i>GNB1</i> is a candidate gene for the known obesity phenotype of the 1p36 microdeletion syndrome given this chromosomal region includes the <i>GNB1</i> gene. Knowledge of an additional obesity phenotype is important for prognosis, early interventions against obesity and awareness when prescribing weight-inducing medication.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.12661","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140716874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kacey Chae, Jashalynn German, Karla Kendrick, Sean Tackett, Paul O'Rourke, Kimberly A. Gudzune, Marci Laudenslager
{"title":"An obesity medicine curriculum increases the obesity care self-efficacy of internal medicine residents in the primary care setting","authors":"Kacey Chae, Jashalynn German, Karla Kendrick, Sean Tackett, Paul O'Rourke, Kimberly A. Gudzune, Marci Laudenslager","doi":"10.1111/cob.12656","DOIUrl":"10.1111/cob.12656","url":null,"abstract":"<div>\u0000 \u0000 <p>Primary care physicians (PCPs) report insufficient knowledge and training gaps in obesity care. Internal Medicine (IM) residency offers an opportunity to address this educational gap for future PCPs. We designed an innovative, multicomponent curriculum on obesity medicine (OM) in the primary care setting for IM residents. We then conducted a prospective, 6-month, two-arm study within two residency programs in Maryland evaluating feasibility (use, appropriateness for IM training, and satisfaction) of the curriculum as well as changes in self-efficacy within seven obesity care domains, assessed on 4-point scales (1—not at all confident to 4—very confident). One residency program received the curriculum and the other served as the control group. We recruited 35 IM residents to participate (17 intervention, 18 control). Among intervention residents, 42% used all curricular components; appropriateness and satisfaction with the curriculum were high. Compared with controls, intervention residents had statistically significant increases in five obesity care self-efficacy domains: nutrition (intervention 0.8 vs. control 0.2, <i>p</i> = .02), behaviour change (1.2 vs. 0.4, <i>p</i> < .01), weight-gain-promoting medications (0.8 vs. 0.1, <i>p</i> = .01), anti-obesity medications (1.2 vs. 0.5, <i>p</i> = .03), and bariatric surgical counselling (0.9 vs. 0.4, <i>p</i> = .03). There were no significant changes in physical activity or post-bariatric surgical care domains. Our OM curriculum is feasible with IM residents and increases residents' obesity care self-efficacy beyond what is achieved with usual IM training.</p>\u0000 </div>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140317925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Linda Jiretorn, My Engström, Cecilia Laursen, Ximena Ramos Salas, Kajsa Järvholm
{"title":"‘My goal was to become normal’—A qualitative investigation of coping with stigma, body image and self-esteem long-term after bariatric surgery","authors":"Linda Jiretorn, My Engström, Cecilia Laursen, Ximena Ramos Salas, Kajsa Järvholm","doi":"10.1111/cob.12657","DOIUrl":"10.1111/cob.12657","url":null,"abstract":"<p>Improved self-esteem and body image, as well as reduced experiences of weight stigma are important patient-reported obesity treatment outcomes. However, more knowledge is needed about how individuals who have undergone metabolic and bariatric surgery (MBS) perceive themselves and their bodies and use different coping strategies in relation to body image and self-esteem long-term after MBS. In this qualitative study body image, self-esteem, weight stigma and coping strategies were explored among 18 individuals who underwent MBS more than 10 years ago when interviewed. Using reflexive thematic analysis, two primary themes were identified: ‘Experiences of living with a stigmatised body’ and ‘Coping with weight stigma, body image and self-esteem’, and eight sub-themes. Findings capture frequent experiences of weight stigma before bariatric surgery, the need for coping with stigma and body dissatisfaction before and after MBS, and how different coping strategies are related to participants' perceptions of their bodies and self-concepts. More adaptive coping strategies, such as confrontation and cognitive restructuring may facilitate more positive body image outcomes, than more ruminative and avoidant strategies. Understanding adaptive coping strategies can be useful to develop interventions to reduce negative consequences of weight stigma on body image and self-esteem.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 3","pages":""},"PeriodicalIF":3.3,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.12657","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140317927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rhiannon Stellmaker, Belinda Thompson, Helen Mackie, Louise Koelmeyer
{"title":"Comparison of fluid and body composition measures in women with lipoedema, lymphoedema, and control participants","authors":"Rhiannon Stellmaker, Belinda Thompson, Helen Mackie, Louise Koelmeyer","doi":"10.1111/cob.12658","DOIUrl":"10.1111/cob.12658","url":null,"abstract":"<p>Lipoedema is the disproportionate accumulation of adipose tissue in the lower body, often associated with hormonal changes in women. Lipoedema is commonly misdiagnosed as lymphoedema or obesity due to similarities in appearance. The aim of this study is to compare body composition and fluid measures of women with lipoedema, lymphoedema, and matched control participants, to determine differences that may help distinguish between each condition. One hundred and eleven participants aged over 18, who presented with the complaint of leg swelling and underwent indocyanine green lymphography were included in this study. Our analysis showed that the individuals with lymphoedema had a significantly higher overall total body water (<i>lymphoedema</i>: 9.6 ± 4.2 L, <i>lipoedem</i>a: 7.4 ± 2.3 L, <i>control</i>: 7.5 ± 1.8 L; <i>p</i> < .001) and extracellular fluid (<i>lymphoedema</i>: 4.6 ± 1.6, <i>lipoedema</i>: 3.4 ± 1.0 L, <i>control</i>: 3.5 ± 0.7 L; <i>p</i> < .001) in the legs when compared to individuals with lipoedema and matched control participants. Individuals with lipoedema had a significantly higher overall fat mass as a percentage of body weight when compared to individuals with lymphoedema (<i>lymphoedema</i>: 33.1% ± 9.5%, <i>lipoedema</i>: 39.4% ± 6.5%; <i>p</i> = .003). We are unable to distinguish between individuals with lipoedema and control participants, therefore further research needs to be conducted to help reduce misdiagnosis.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.12658","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140317926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathan Gabison, Beatrice Palazzolo, Christina Saleh, Olivia Ritchie, Kayla Sheehan, Amal Othman, Diane M. Harper, Lauren Oshman
{"title":"Supporting faculty development for obesity education: A National Survey of United States family medicine residency programme directors","authors":"Jonathan Gabison, Beatrice Palazzolo, Christina Saleh, Olivia Ritchie, Kayla Sheehan, Amal Othman, Diane M. Harper, Lauren Oshman","doi":"10.1111/cob.12654","DOIUrl":"10.1111/cob.12654","url":null,"abstract":"<p>Obesity is the most common chronic condition in the United States (US), yet primary care physicians face barriers in providing obesity treatment. This study examines the prevalence of American Board of Obesity Medicine (ABOM) certified obesity specialists on the faculty of US Family Medicine residency training programmes, the preparedness of graduating resident physicians to treat obesity, and residency training programme director preferences for supporting faculty development to improve residency education in obesity management. This cross-sectional on-line survey of programme directors addressed the number of ABOM-certified faculty, perceived graduate preparedness to treat obesity, and priorities to improve faculty expertise and obesity curriculum. Of 672 eligible programme directors, 298 (44%) responded to our survey. Most programmes (76%) had no ABOM-certified faculty. The proportion of programme directors assessing their graduates as prepared to care for patients with obesity has significantly decreased in the last 5 years (2018: 74%, 2022: 58%, <i>p</i> = .016). Residents in programmes with ABOM-certified faculty member were more likely to be assessed as very prepared to provide medical care (18% vs. 7.8% <i>p</i> = .047). A majority (54%) of programme directors identified limited faculty training and expertise as the biggest faculty and resident-level barrier to quality obesity care. This study demonstrates an important trend towards increasing ABOM-certification among Family Medicine residency programme faculty and an urgent need to prioritise faculty development to improve faculty expertise and resident training to address the obesity epidemic.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.12654","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140206432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elizabeth Ryan, Helen MacLaughlin, Robin Hay, Andrea Cawte, Leonie Naumann, Gemma Woodruff, Michelle Cottrell, Peter Window
{"title":"Improving multidisciplinary management of patients living with obesity: The evaluation of seated bioimpedance measures and relationship to functional performance following targeted intervention","authors":"Elizabeth Ryan, Helen MacLaughlin, Robin Hay, Andrea Cawte, Leonie Naumann, Gemma Woodruff, Michelle Cottrell, Peter Window","doi":"10.1111/cob.12655","DOIUrl":"10.1111/cob.12655","url":null,"abstract":"<div>\u0000 \u0000 <p>Management of obesity requires a multidisciplinary approach including physical activity interventions, which have significant impacts on overall health outcomes. Greater levels of lean muscle mass are significantly associated with improved health and reduced risk of comorbidities and should be preserved where possible when undertaking rapid weight loss. This article reports on the physical and functional outcomes achieved during a 12-week intensive multidisciplinary intervention targeting obesity and evaluates correlations between body composition and functional outcomes. We additionally aimed to investigate the test–retest reliability and levels of agreement in body composition measurements using bioimpedance spectroscopy between seated and standing positions. Of the 35 participants included in analysis, significant differences were observed between baseline and post-intervention measures. These included weight loss of 12.6 kg, waist circumference reduction of 10.5 cm, fat mass reduction by 2.9%, muscle mass increase by 1.6%, 54.5 m improvement in the 6-minute walk test and 3.8 rep improvement in the 30-second sit-to-stand test. No significant correlations were observed between physical and functional outcome measures. Excellent test re-test reliability was observed in bioimpedance spectroscopy seated measurements (ICC >.9). Significant differences were observed between seated and standing bioimpedance spectroscopy measurements, however they are regarded as small differences in a clinical setting.</p>\u0000 </div>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140130932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}