Surbhi Sood , Amy Sylivris , Ayesha Sualeheen , David Scott , Sze-Yen Tan , Anthony Villani , Brenton Baguley , Elena S. George
{"title":"The effects of Mediterranean diet on body composition outcomes in adults with chronic disease: A systematic review and meta-analysis of clinical trials","authors":"Surbhi Sood , Amy Sylivris , Ayesha Sualeheen , David Scott , Sze-Yen Tan , Anthony Villani , Brenton Baguley , Elena S. George","doi":"10.1016/j.clnesp.2025.01.012","DOIUrl":"10.1016/j.clnesp.2025.01.012","url":null,"abstract":"","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"66 ","pages":"Page 576"},"PeriodicalIF":2.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143621352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improving energy and protein intake via an oral nutrition support pathway in the intensive care unit and beyond","authors":"Alicia Wiese , Emma Ballard","doi":"10.1016/j.clnesp.2025.01.008","DOIUrl":"10.1016/j.clnesp.2025.01.008","url":null,"abstract":"","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"66 ","pages":"Page 575"},"PeriodicalIF":2.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143621237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kate Connell , Emma McShane , Andrea Elliott , Lauren Hanna , Kate Furness
{"title":"Screening, diagnosing and treating malnutrition in the hospital setting: A large-scale point prevalence study","authors":"Kate Connell , Emma McShane , Andrea Elliott , Lauren Hanna , Kate Furness","doi":"10.1016/j.clnesp.2025.01.013","DOIUrl":"10.1016/j.clnesp.2025.01.013","url":null,"abstract":"","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"66 ","pages":"Pages 576-577"},"PeriodicalIF":2.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lisa Murnane , Adrienne Forsyth , Eldho Paul , Audrey Tierney , Paul Burton
{"title":"Body composition changes and the impact of obesity during surgical treatment for oesophagogastric cancer","authors":"Lisa Murnane , Adrienne Forsyth , Eldho Paul , Audrey Tierney , Paul Burton","doi":"10.1016/j.clnesp.2025.01.006","DOIUrl":"10.1016/j.clnesp.2025.01.006","url":null,"abstract":"","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"66 ","pages":"Page 574"},"PeriodicalIF":2.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143621235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dimitrios Poulimeneas , Costas A. Anastasiou , Evgenia-Eleni Vlachogianni , Amalia Charokopou , Myrto Bitsa , Sai Krupa Das , Drew Sayer , Susan B. Roberts , James O. Hill , Mary Yannakoulia
{"title":"A pilot study on traditional vs. digital self-administered questionnaire completion in the International Weight Control Registry","authors":"Dimitrios Poulimeneas , Costas A. Anastasiou , Evgenia-Eleni Vlachogianni , Amalia Charokopou , Myrto Bitsa , Sai Krupa Das , Drew Sayer , Susan B. Roberts , James O. Hill , Mary Yannakoulia","doi":"10.1016/j.clnesp.2025.03.015","DOIUrl":"10.1016/j.clnesp.2025.03.015","url":null,"abstract":"<div><h3>Background & aim</h3><div>Scarce reports on the characteristics of individuals choosing to enroll in obesity-related registries via digital or traditional methods exist. We examined whether characteristics of participants who enrolled in the International Weight Control Registry (IWCR) via digital surveys differed from those who enrolled with paper surveys.</div></div><div><h3>Methods</h3><div>This manuscript describes the pilot phase of IWCR recruitment of eligible participants from one collaborating country. The IWCR includes questionnaires capturing biological, behavioral, environmental and psychosocial domains of weight management. All adult individuals with an intentional weight loss history, regardless of it being successful or not, are eligible to participate. Two invitations for participation were sent out. Firstly, potential participants were invited to complete the survey digitally; then, in the second invitation, potential volunteers were invited to complete the survey on paper.</div></div><div><h3>Results</h3><div>A total of 69 persons with weight loss experiences completed this pilot survey (40 on-paper, 29 digitally). No differences were detected in the sex distribution and the level of education between groups (all p > 0.05). Fewer participants in the on-paper group reported to have experienced significant weight loss in their adult life (70.0 vs 100 %, p = 0.001). Maximum Body Mass Index (BMI) and initial weight loss (%) were similar in both groups, however the digital group reported significantly greater weight loss maintenance (86.5 vs 43.8 % of the initial weight loss, p = 0.008). More persons in the digital group reported to have achieved their current weight by linear weight loss (rapid or not) vs. through a series of weight loss cycles (p = 0.008).</div></div><div><h3>Conclusion</h3><div>The different modes of engagement (digital vs. paper) may target different people. Traditional means of questionnaire completion were more appealing in individuals with less successful weight loss efforts. These preliminary results suggest that offering both online and paper versions of registry questionnaires may support data collection in a broader population demographic.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"67 ","pages":"Pages 174-177"},"PeriodicalIF":2.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Everson A. Nunes , Alysha C. D'Souza , Jeremy P. Steen, Stuart M. Phillips
{"title":"Lack of evidence for Omega-3 fatty acid supplementation in enhancing lean mass, muscle strength, and physical function in healthy adults and clinical populations: An overview of reviews","authors":"Everson A. Nunes , Alysha C. D'Souza , Jeremy P. Steen, Stuart M. Phillips","doi":"10.1016/j.clnesp.2025.03.012","DOIUrl":"10.1016/j.clnesp.2025.03.012","url":null,"abstract":"<div><h3>Background & aims</h3><div>N-3 (omega-3) polyunsaturated fatty acids (n-3-PUFA) have been hypothesized to enhance/maintain skeletal muscle mass, strength, and physical function. We conducted an overview of reviews of n-3 fatty acid monotherapy supplementation and examined whether the evidence supports the effects in healthy young and old adults and clinical populations.</div></div><div><h3>Methods</h3><div>In line with the PRISMA guidelines, a widely accepted framework for conducting and reporting systematic reviews, we conducted a comprehensive search for systematic reviews (OVID, Embase, Web of Science, SPORTDiscus) reporting the effect of n-3 fatty acid supplementation in our target populations. To ensure the reliability and validity of our findings, the methodological quality of the reviews was assessed using A Measurement Tool to Assess Systematic Reviews (AMSTAR) 1, a validated tool for appraising the methodological quality of systematic reviews.</div></div><div><h3>Results</h3><div>Thirty-three systematic reviews met our inclusion criteria: 19 non-oncologic, 11 oncologic, and 3 mixed. In non-oncologic populations, 4 out of 16 reviews showed some evidence that n-3-PUFA supplementation benefitted lean mass, with 3 reviews focusing on older populations. For strength, 1 out of 14 reviews found sufficient evidence in favor, while 3 others reported some evidence of n-3-PUFA ingestion. For physical function, 1 out of 15 reviews found sufficient evidence, and 3 reported some evidence favoring n-3-PUFA use. In oncologic participants, only 1 out of 13 reviews found sufficient evidence that n-3-PUFA improved lean mass. No reviews found sufficient evidence for strength or physical function improvements.</div></div><div><h3>Conclusions</h3><div>Our analysis indicates limited evidence supporting the effectiveness of n-3-PUFA supplementation in both younger and older healthy adults, as well as clinical populations including oncologic patients, to improve or prevent loss of lean mass. Most systematic reviews concluded that n-3-PUFA supplementation did not significantly affect strength, or studies were inconclusive, and there was no consistent impact of n-3-PUFA supplementation on functional outcome measures. These findings underscore the need for further research to better understand the role of n-3-PUFA in muscle health and to guide clinical practice. Our analysis does not support n-3-PUFA monotherapy for lean mass gain/retention enhancing strength or function in healthy young and older persons, and oncologic populations.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"67 ","pages":"Pages 155-165"},"PeriodicalIF":2.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael S. Yule , Andressa M. Machado , Leo R. Brown , Bruna M.M. Rocha , Rebekah Patton , Judith Sayers , Iona Munro , Jennifer Baxter , Amy McLuskie , Paula P. Lajolo , Jann Arends , Carlos E. Paiva , Mark Stares , Duncan Brown , Iain Phillips , Donald C. McMillan , Yara C.P. Maia , Richard J.E. Skipworth , Barry J.A. Laird
{"title":"Dissecting the global leadership initiative on malnutrition criteria in advanced cancer: Reduced intake vs. inflammation","authors":"Michael S. Yule , Andressa M. Machado , Leo R. Brown , Bruna M.M. Rocha , Rebekah Patton , Judith Sayers , Iona Munro , Jennifer Baxter , Amy McLuskie , Paula P. Lajolo , Jann Arends , Carlos E. Paiva , Mark Stares , Duncan Brown , Iain Phillips , Donald C. McMillan , Yara C.P. Maia , Richard J.E. Skipworth , Barry J.A. Laird","doi":"10.1016/j.clnesp.2025.03.007","DOIUrl":"10.1016/j.clnesp.2025.03.007","url":null,"abstract":"<div><h3>Background & aims</h3><div>The Global Leadership Initiative on Malnutrition (GLIM) criteria have been recommended for the diagnosis of malnutrition. It requires that the patient meets at least one phenotypic criterion and at least one aetiological criterion. For the latter, the patient must either demonstrate reduced food intake or have evidence of systemic inflammation. As both are common in advanced cancer, the aim of the present study was to determine, in patients who met the GLIM phenotypical criteria, which GLIM aetiological criteria (reduced food intake or systemic inflammation) is most useful in predicting overall survival (OS).</div></div><div><h3>Methods</h3><div>Data from two cancer biobanks were combined. Inclusion criteria were: ≥18 years, advanced cancer (stage III or IV) and ability to provide written consent. Weight loss (WL) was selected as the phenotypic criterion of choice, as preliminary analysis demonstrated it to be a superior predictor of OS compared to body mass index. Malnutrition type 1 was defined as >5 % WL over 6 months and a C reactive protein (CRP) ≥3 mg/l. Further analysis was performed with a CRP >10 mg/l cut-off. Malnutrition type 2 was defined as >5 % WL over 6 months and reduced food intake, as reported in the Patient Generated Subjective Global Assessment. Survival was assessed using Kaplan-Meier methodology, log-rank tests and Cox proportional hazards models, with hazard ratios (HR) and confidence intervals (CI) reported.</div></div><div><h3>Results</h3><div>In total, 176 patients were studied, with 147 events observed. The 3-month mortality rate was 32.4 % (CI: 25.1 to 39.0) and the 1-year mortality rate was 71.8 % (CI: 63.8 to 78.0). Malnutrition type 1 and malnutrition type 2 were observed in 37.8 % (HR: 2.27 [CI: 1.54 to 3.33], p < 0.001) and 26.3 % (HR: 1.74 [CI: 1.19 to 2.54], p = 0.005) of patients respectively, with both significantly increasing the risk of death. Following adjustment for relevant confounders both malnutrition type 1 (HR: 1.92 [CI: 1.25 to 2.94], p = 0.003) and malnutrition type 2 (HR: 1.61 [CI: 1.09 to 2.38], p = 0.019) remained significant predictors of OS. Median survival for patients with malnutrition type 1 was 2.14 (CI: 1.74 to 4.90) months compared to 9.5 (6.94–13.64) months for those without (<em>p</em> < 0.001). For malnutrition type 2, this was 2.37 (CI: 1.64 to 5.46) vs. 7.40 months (CI: 6.08 to 10.16), p = 0.004. When the CRP threshold was increased to >10 mg/l, malnutrition type 1 was observed in fewer patients (30.4%), median survival was shorter (1.91 [CI: 1.25 to 2.99] vs. 9.86 months [CI: 7.27 to 14.7], <em>p</em> < 0.001) and in both univariable (HR: 2.91 [CI: 1.94 to 4.63], <em>p</em> < 0.001) and multivariable (HR: 2.32 [CI: 1.50 to 3.60], <em>p</em> < 0.001) analyses, the risk of death increased.</div></div><div><h3>Conclusion</h3><div>The results suggest that the inflammatory component of GLIM appears superior compared to re","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"67 ","pages":"Pages 114-121"},"PeriodicalIF":2.9,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Specific clinical conditions for colloids use","authors":"Michał P. Pluta, Łukasz J. Krzych","doi":"10.1016/j.clnesp.2025.03.014","DOIUrl":"10.1016/j.clnesp.2025.03.014","url":null,"abstract":"<div><div>Intravenous fluids are among the most commonly prescribed drugs. Many preparations classified by composition as crystalloids or colloids, of natural or synthetic origin, are available in clinical practice. Guidelines favor crystalloids as first-choice fluids in most clinical situations, mainly because of the lack of advantage of using colloids in reducing mortality and organ complications and generating higher treatment costs. This review focuses on the evidence for the use of colloids in selected clinical conditions.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"67 ","pages":"Pages 122-126"},"PeriodicalIF":2.9,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}