Clinical nutrition ESPEN最新文献

{"title":"Predictive factors of weight loss in obese patients referred to an obesity specialized centre","authors":"Marie-Océane Guittière ,&nbsp;Estelle Le Pabic ,&nbsp;Teycir Zayani ,&nbsp;Mickaël Som ,&nbsp;Ronan Thibault","doi":"10.1016/j.clnesp.2024.08.020","DOIUrl":"10.1016/j.clnesp.2024.08.020","url":null,"abstract":"<div><h3>Introduction and aims</h3><p>In obese patients, long-term weight loss maintenance remains challenging. Identifying factors predicting adhesion to lifestyle therapy and weight loss would help optimizing obesity management. Aims: to identify predictive factors of weight loss after one year of medical therapy in obese patients (primary) and predictive factors of drop-out during the year of therapy (secondary).</p></div><div><h3>Methods</h3><p>In this retrospective study, obese patients consulting for the first time in an obesity specialized center were included. All patients fulfilled the criteria for obesity surgery and were managed to change their lifestyle by following a 1-year therapeutical education program based on intuitive eating. Significant weight loss was defined by ≥ 5 % after 1 year. Patients were considered as dropouts, i.e. absence of adhesion to therapy, once they missed one consultation without informing the unit. Stepwise multivariable analyses determined the predictive factors.</p></div><div><h3>Results</h3><p>Of the 310 patients (mean age, 44.5 ± 11.9 yr, 79% women) included, 155 (50%) maintained their follow-up at 1 year and 37 (24%) experienced weight loss ≥5%. Male gender (odds ratio (OR) = 6.25 [95% confidence interval, 1.78; 21.92], P = 0.004), ≥5 consultations with intuitive eating (OR = 3.69 [1.14; 11.87], P = 0.03), and tobacco addiction (OR = 0.18 [0.04; 0.82], P = 0.03) were associated to weight loss ≥5%. Older age (OR = 0.97 [0.95; 0.99], P = 0.014), physical activity (OR = 0.11 [0.05; 0.24], P &lt; 0.0001) and the patient desire for obesity surgery (OR = 0.22 [0.12; 0.41], P &lt; 0.0001) were associated with a better adhesion to therapy.</p></div><div><h3>Conclusion</h3><p>The identified predictive factors would help identifying the patients with the greater chance of losing weight and adhering to therapy. Offering more therapeutic education sessions should increase therapy success in obese patients fulfilling the criteria for obesity surgery.</p></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"63 ","pages":"Pages 959-969"},"PeriodicalIF":2.9,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of metabolic alterations as 30 days intensive care mortality predictors for patients undergoing continuous renal replacement therapy","authors":"Vaidas Vicka ,&nbsp;Alvita Vickiene ,&nbsp;Sigute Miskinyte ,&nbsp;Ieva Bartuseviciene ,&nbsp;Ingrida Lisauskiene ,&nbsp;Mindaugas Serpytis ,&nbsp;Donata Ringaitiene ,&nbsp;Jurate Sipylaite","doi":"10.1016/j.clnesp.2024.08.021","DOIUrl":"10.1016/j.clnesp.2024.08.021","url":null,"abstract":"<div><h3>Background</h3><p>Acute kidney injury patients on continuous renal replacement therapy are subjected to alterations in metabolism, which in turn are associated with worse clinical outcome and mortality. The aim of this study is to determine which metabolism indicators can be used as independent predictors of 30 days intensive care unit (ICU) mortality.</p></div><div><h3>Methods</h3><p>This was a prospective observational study on critical care patients on renal replacement therapy. Integrated approach of metabolism evaluation was used, combining the energy expenditure measured by indirect calorimetry, bioelectrical impedance provided fat free mass index (FFMI), amino acid and glucose concentrations. ICU mortality was defined as all cause 30 days mortality. Regression analysis was conducted to determine the conventional and metabolism associated predictors of mortality.</p></div><div><h3>Results</h3><p>The study was conducted between the 2021 March and 2022 October. 60 high mortality risk patients (APACHE II of 22.98 ± 7.87, 97% on vasopressors, 100% on mechanical ventilation) were included during the period of the study. The rate of 30 days ICU mortality was 50% (n = 30). Differences across survivors and non-survivors in metabolic predictors were noted in energy expenditure (kcal/kg/day) (19.79 ± 5.55 vs 10.04 ± 3.97 p = 0.013), amino acid concentrations (mmol/L) (2.40 ± 1.06 vs 1.87 ± 0.90 p = 0.040) and glucose concentrations (mmol/L) (7.89 ± 1.90 vs 10.04 ± 3.97 p = 0.010). No differences were noted in FFMI (23.38 ± 4.25 vs 21.95 ± 3.08 p = 0.158). In the final linear regression analysis model, lower energy expenditure (exp(B) = 0.852 CI95%: 0.741–0.979 p = 0.024) and higher glucose (exp(B) = 1.360 CI95%: 1.013–1.824 p = 0.041) remained as independent predictors of the higher mortality.</p></div><div><h3>Conclusion</h3><p>The results of the study imply strong association between the metabolic alterations and ICU outcome. Our findings suggest that lower systemic amino acid concentration, lower energy expenditure and higher systemic glucose concentration are predictive of 30 days ICU mortality.</p></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"63 ","pages":"Pages 944-951"},"PeriodicalIF":2.9,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405457724012920/pdfft?md5=6089a4c8e9c3cbe2e839a57e8b5d9b20&pid=1-s2.0-S2405457724012920-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association of body weight change and regression to normoglycemia in different phenotypes of pre-diabetes: Findings of a longitudinal cohort study","authors":"Zahra Bahadoran ,&nbsp;Parvin Mirmiran ,&nbsp;Fereidoun Azizi ,&nbsp;Farhad Hosseinpanah","doi":"10.1016/j.clnesp.2024.08.024","DOIUrl":"10.1016/j.clnesp.2024.08.024","url":null,"abstract":"<div><h3>Aim</h3><p>We investigated the association of a 3-year change in body weight (BW) and regression to normal glucose regulation (NGR) among different phenotypes of pre-diabetes (Pre-DM), i.e., isolated impaired glucose tolerance (iIGT), isolated impaired fasting glucose (iIFG) and combined IFG-IGT.</p></div><div><h3>Research design and methods</h3><p>1458 Pre-DM subjects (iIFG = 618, iIGT = 462, and IFG-IGT = 378) were assessed for 3-year change-percent in BW (2006–2008 to 2009–2011) and then followed up to 2015–2017, within the national cohort of Tehran Lipid and Glucose Study (TLGS). Binary logistic regression models were used to estimate the probability (odds ratio, ORs) of regression to NGR across categories of 3-year BW change (i.e., ≥5% BW loss, &lt;5% BW loss, BW gain) in different phenotypes of Pre-DM.</p></div><div><h3>Results</h3><p>The mean age of the participants was 53.0 ± 13.7, and 46.8% were men. Over a median of 6 years of follow-up, the rate of regression to normoglycemia was 50.6, 43.2, and 12.7% in iIGT, iIFG, and combined IFG-IGT, respectively. The baseline-adjusted mean of 3-year BW change was not significantly different across Pre-DM phenotypes (0.68 ± 0.19, 0.32 ± 0.22, and 0.23 ± 0.24 kg, in iIFG, iIGT, and IFG-IGT). Three-year BW loss ≥5% was associated with a greater NGR probability in iIGT than other phenotypes (OR = 4.29 <em>vs.</em> 3.90 and 2.84 in IFG-IGT and iIFG, respectively). A modest reduction (&lt;5% of initial BW) resulted in an increased chance of Pre-DM regression among subjects with iIGT (OR = 1.61, 95% CI = 1.03–2.52) but not iIFG or IFG-IGT phenotypes.</p></div><div><h3>Conclusion</h3><p>Short-term intensive BW loss (≥5% of initial BW) increased NGR probability in all Pre-DM phenotypes, with an order of iIGT &gt; combined IFG-IGT &gt; iIFG. Only iIGT takes advantage of moderate BW loss (&lt;5% of initial BW) to increase the chance of Pre-DM regression.</p></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"63 ","pages":"Pages 887-892"},"PeriodicalIF":2.9,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficiency of a technology-assisted nutritional screening system: A retrospective analysis of 11,722 admissions in a tertiary hospital","authors":"Frank Carrera-Gil ,&nbsp;María Isabel Prieto Rusca","doi":"10.1016/j.clnesp.2024.08.022","DOIUrl":"10.1016/j.clnesp.2024.08.022","url":null,"abstract":"<div><h3>Background and aim</h3><p>Nutritional screening is essential for addressing malnutrition and its consequences. However, routine implementation in large hospitals faces several challenges. To overcome these obstacles, the Clinical Nutrition Service of a tertiary hospital developed a technology-assisted nutritional screening system. This study evaluates the system's efficiency in detecting and assessing patients at nutritional risk upon hospital admission. It also examines the association between nutritional risk, clinical outcomes, and sociodemographic characteristics.</p></div><div><h3>Methods</h3><p>This retrospective, analytical, observational study examined 11,722 hospital admissions of adult patients in 2019, each with a minimum hospital stay of 48 hours (h) in a tertiary hospital. Rates and timing for the detection, referral, and assessment of patients at nutritional risk were calculated. Participants were divided into low (Malnutrition Screening Tool [MST] &lt; 2 points) and moderate/high (MST ≥2) nutritional risk groups to evaluate the relationship between nutritional risk and clinical and demographic variables.</p></div><div><h3>Results</h3><p>We found that 91% of patients underwent nutritional screening within the first hours of admission, with a median time of 9 h from admission to screening (interquartile range [IQR] 3–19). The prevalence of nutritional risk (MST ≥2) was 21%. All patients identified as being at nutritional risk were immediately referred for a nutritional assessment once identified, with a median referral time of 0 h (IQR 0-0). This assessment was carried out by a nutritionist for 98% of these patients, with a median time of 19 h from referral to assessment (IQR 6–24). Compared to the low-risk group, patients with nutritional risk were older, had higher rates of mortality and admission to the intensive care unit (ICU), longer hospital stays, and a higher proportion of men and cancer diagnoses (p&lt; 0.001 for all comparisons). After adjusting for age and sex, nutritional risk was significantly associated with a higher probability of ICU admission (Odds Ratio [OR] 1.13; 95% CI 1.02–1.24) and in-hospital mortality (OR 2.32; 95% CI 1.97–2.73).</p></div><div><h3>Conclusion</h3><p>The integration of technology into nutritional screening was highly efficient for early detection and assessment of at-risk patients upon hospital admission. Features of this system could guide other hospitals. The association found between nutritional risk and clinical outcomes emphasizes the importance of prompt and appropriate nutritional interventions.</p></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"64 ","pages":"Pages 51-56"},"PeriodicalIF":2.9,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405457724012932/pdfft?md5=ca45eaf4be312f01194823c44037c533&pid=1-s2.0-S2405457724012932-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implemented nutritional intervention algorithm in pediatric oncology compared to standard nutritional supportive care outcomes","authors":"Judy Schoeman ,&nbsp;Ilde-Marié Kellerman ,&nbsp;Elena J. Ladas ,&nbsp;Sandile Ndlovu ,&nbsp;Paul C. Rogers ,&nbsp;Jan du Plessis ,&nbsp;Mariechen Herholdt ,&nbsp;David T. Reynders ,&nbsp;Gita Naidu ,&nbsp;Biance Rowe ,&nbsp;Karla Thomas ,&nbsp;Barry Vanemmenes ,&nbsp;Rema Mathews ,&nbsp;Ané Büchner ,&nbsp;Fareed E. Omar ,&nbsp;Uys Ronelle ,&nbsp;Mariana Kruger","doi":"10.1016/j.clnesp.2024.08.019","DOIUrl":"10.1016/j.clnesp.2024.08.019","url":null,"abstract":"<div><h3>Aim</h3><p>To implement a childhood cancer-specific nutritional algorithm adapted for the South African context for interventions at time-set intervals to evaluate differences in the nutritional status of newly diagnosed children with cancer.</p></div><div><h3>Method</h3><p>Children with newly diagnosed cancer were assessed for stunting, underweight, wasting, and moderate to severe malnutrition (MUAC &lt; -2SD and &lt; - 3 SD) between October 2018 and December 2020 in a longitudinal nutritional assessment study with monthly assessments. Two pediatric oncology units (POUs) served as the intervention group that implemented the nutritional algorithm-directed intervention and three other POUs formed the control group that implemented standard supportive nutritional care.</p></div><div><h3>Results</h3><p>A total of 320 patients were enrolled with a median age of 6.1 years (range three months to 15.3 years) and a male-to-female ratio of 1.1:1. The malnourished patients in the intervention group showed significant improvement at six months after diagnosis for stunting (<em>P</em> = 0.028), underweight (<em>P</em> &lt; 0.001), and wasting until month five (<em>P</em> = 0.014). The improvements in the control group were not significant. Moderate acute malnutrition (MAM) significantly improved over the first six months of cancer treatment in the intervention group (<em>P</em> &lt; 0.001), while MAM improvement was only significant in the control group for the children under five years of age (<em>P</em> = 0.004). The difference in mean z-scores over time for the nutritional parameters between the intervention and control groups was insignificant.</p></div><div><h3>Conclusion</h3><p>We established that the nutritional algorithm adapted for South Africa as an intervention tool for childhood cancer assisted in optimizing nutritional interventions and improved nutritional outcomes over the first six months of cancer treatment.</p></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"63 ","pages":"Pages 870-877"},"PeriodicalIF":2.9,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405457724012907/pdfft?md5=0ef44da249954ab8817f4fe0e370f64f&pid=1-s2.0-S2405457724012907-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142092472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of a pre-meal snack and/or postprandial exercise on breakfast glycemic excursion in adults with cystic fibrosis: A pilot study","authors":"Anne Bonhoure ,&nbsp;Johann Colomba ,&nbsp;Valérie Boudreau ,&nbsp;Adèle Coriati ,&nbsp;Valérie Parent ,&nbsp;Marie Devaux ,&nbsp;Delphine Bouchard ,&nbsp;Annick Lavoie ,&nbsp;Rémi Rabasa-Lhoret","doi":"10.1016/j.clnesp.2024.08.016","DOIUrl":"10.1016/j.clnesp.2024.08.016","url":null,"abstract":"<div><h3>Background &amp; aims</h3><p>Cystic fibrosis (CF)-related diabetes (CFRD), a common comorbidity in CF, is often preceded and characterized with elevated postprandial glycemic (PPG) excursions. In the general population, the consumption of a pre-meal protein snack and/or physical activity (PA) hinder the elevation of PPG levels. Our objective is to evaluate the effect of a pre-meal snack and/or post-meal PA on PPG excursions in CF.</p></div><div><h3>Methods</h3><p>This is a double-blinded randomized controlled crossover interventional study in 14 adults with CF, with 4 interventions: placebo pre-meal snack + no PA (control: CTL), pre-meal soy snack + no PA (SK), placebo pre-meal snack + PA (PA), and pre-meal soy snack + PA (SK + PA). The pre-meal soy snack or placebo beverage (vanilla flavoured water) is served at 8 AM, followed by a standardized breakfast at 9 AM and, postprandially, 5 repeated bouts of 3-min walk every 30 min or sedentary activity. Blood glucose and insulin were measured every 15–30 min during the interventions.</p></div><div><h3>Results</h3><p>Plasma glucose (PG) was higher 30 min after snack consumption compared to placebo beverage. One-hour post-breakfast, PG levels were lower during both PA interventions than with sedentary behavior. However, the overall 3 h post-breakfast glucose area under the curve (AUC) was similar between interventions. Post-breakfast 3 h insulin AUC was significantly lower during the SK + PA intervention compared to the sedentary behavior interventions.</p></div><div><h3>Conclusion</h3><p>Repeated short bouts of post-meal physical activity may positively impact PPG control in adults with CF, with or without the addition of a pre-meal soy snack. A pre-meal snack alone does not improve PPG.</p></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"63 ","pages":"Pages 952-958"},"PeriodicalIF":2.9,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405457724012877/pdfft?md5=b592edd377b2d1053ced6e431f591663&pid=1-s2.0-S2405457724012877-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of a new definition of sarcopenic obesity in middle-aged and older adults and association with cognitive function: Findings from the National Health and Nutrition Examination Survey 1999–2002","authors":"Uraiporn Booranasuksakul ,&nbsp;Kostas Tsintzas ,&nbsp;Ian Macdonald ,&nbsp;Blossom CM. Stephan ,&nbsp;Mario Siervo","doi":"10.1016/j.clnesp.2024.08.017","DOIUrl":"10.1016/j.clnesp.2024.08.017","url":null,"abstract":"<div><h3>Background &amp; aims</h3><p>The role of sarcopenic obesity (SO) in impaired cognitive function has been investigated in several observational studies, but results have been mixed. This study applied the proposed European Society for Clinical Nutrition and Metabolism (ESPEN)-European Association for the Study of Obesity (EASO) definition of SO to a representative population aged ≥50 years to identify the association between SO and cognitive function.</p></div><div><h3>Methods</h3><p>Data from the National Health and Nutrition Examination Survey 1999–2002 waves were used. At the screening phase, body mass index or waist circumference were used to evaluate obesity; sarcopenia was identified using the SARC-F questionnaire. At the diagnostic phase I and II, sarcopenia was assessed using knee extensor isometric strength and appendicular lean mass, and fat mass percent was used to assess obesity. Cognitive function in older participants (60–85 years) was assessed using the Digit Symbol Substitution Test. A self-reported memory question was used in middle-aged individuals (50–59 years).</p></div><div><h3>Results</h3><p>The sample included 2356 participants (men, 44.7%). The prevalence of SO was 32.3%, 21.2% and 15.0% at the screening, diagnosis I, and diagnosis II, respectively. Significant associations between SO and cognitive impairment were observed in individuals aged 60–85 at diagnosis I (OR: 2.3, 95%CI 1.4–3.8, P = 0.007) and diagnosis II (OR: 2.7, 95%CI 1.5–4.9, P = 0.004).</p></div><div><h3>Conclusion</h3><p>The new ESPEN-EASO definition of SO identified a high prevalence of SO cases. A significant association between SO and poor cognitive function in older individuals was observed.</p></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"63 ","pages":"Pages 919-928"},"PeriodicalIF":2.9,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405457724012889/pdfft?md5=f9f4547868f39d37f0004f23686ec335&pid=1-s2.0-S2405457724012889-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142055149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intradialytic eating practices and health outcomes among hemodialysis patients, cross-sectional study","authors":"May Hamdan ,&nbsp;Fatima Al-Amouri ,&nbsp;Ayat Ali Aljondi ,&nbsp;Eman Dweik ,&nbsp;Tarteel Al-joubeh ,&nbsp;Thabat Al jondi ,&nbsp;Manal Badrasawi","doi":"10.1016/j.clnesp.2024.08.012","DOIUrl":"10.1016/j.clnesp.2024.08.012","url":null,"abstract":"<div><h3>Background and aims</h3><p>Intradialytic eating practices is a subject of debate among hemodialysis patients and is associated with a variety of clinical implications. This study aimed to investigate eating practices during hemodialysis and their influence on health outcome, including various symptoms experienced during dialysis, intradialytic hypotension, dialysis adequacy, and malnutrition.</p></div><div><h3>Methods</h3><p>A cross-sectional study was conducted on hemodialysis patients. A structured questionnaire was used to collect information related to sociodemographic, medical history, lifestyle, dialysis, and eating practices. The occurrence of intradialytic hypotension was determined according to the patients' blood pressure measured at the beginning and end of the session, and dialysis adequacy was determined based on the ultrafiltration rate of the patients. Malnutrition was evaluated using renal inpatient screening tool (renal iNUT), and biochemical data was recruited from the patient's hospital records.</p></div><div><h3>Results</h3><p>A total of 260 hemodialysis patients participated in this study. The mean age was 51.29 ± 15.92, and half of the participants were females. The findings showed no significant association between intradialytic eating practices and symptoms developed during dialysis session, intradialytic hypotension, or malnutrition (p &gt; 0.05). According to Chi-square test, a statistically significant association was found between eating practices and dialysis adequacy (p = 0.037), hemoglobin level (p &lt; 0.001), and phosphorous level (p = 0.003).</p></div><div><h3>Conclusion</h3><p>Eating practices were not associated with symptoms that developed during dialysis sessions, intradialytic hypotension, or malnutrition, according to our findings. However, findings reveal that it is possible that eating practices may affect the adequacy of dialysis.</p></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"63 ","pages":"Pages 768-775"},"PeriodicalIF":2.9,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142035373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeting the microbiome to improve human health with the approach of personalized medicine: Latest aspects and current updates","authors":"Vani Shukla ,&nbsp;Shikha Singh ,&nbsp;Shrikant Verma ,&nbsp;Sushma Verma ,&nbsp;Aliya Abbas Rizvi ,&nbsp;Mohammad Abbas","doi":"10.1016/j.clnesp.2024.08.005","DOIUrl":"10.1016/j.clnesp.2024.08.005","url":null,"abstract":"<div><p>The intricate ecosystem of microorganisms residing within and on the human body, collectively known as the microbiome, significantly influences human health. Imbalances in this microbiome, referred to as dysbiosis, have been associated with various diseases, prompting the exploration of novel therapeutic approaches. Personalized medicine, Tailors treatments to individual patient characteristics, offers a promising avenue for addressing microbiome-related health issues. This review highlights recent developments in utilizing personalized medicine to target the microbiome, aiming to enhance health outcomes. Noteworthy strategies include fecal microbiota transplantation (FMT), where healthy donor microbes are transferred to patients, showing promise in treating conditions such as recurrent <em>Clostridium difficile</em> infection. Additionally, probiotics, which are live microorganisms similar to beneficial gut inhabitants, and prebiotics, non-digestible compounds promoting microbial growth, are emerging as tools to restore microbiome balance. The integration of these approaches, known as synbiotics, enhances microbial colonization and therapeutic effects. Advances in metagenomics and sequencing technologies provide the means to understand individual microbiome profiles, enabling tailored interventions. This paper aims to present the latest insights in leveraging personalized medicine to address microbiome-related health concerns, envisioning a future where microbiome-based therapies reshape disease management and promote human health.</p></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"63 ","pages":"Pages 813-820"},"PeriodicalIF":2.9,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142046380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of coffee and tea consumption on glioma risk: An umbrella review of systematic reviews and meta-analyses","authors":"Hamid Abbasi ,&nbsp;Emad Alem ,&nbsp;Farnush Bakhshimoghaddam ,&nbsp;Sara khoshdooz ,&nbsp;Saeid Doaei","doi":"10.1016/j.clnesp.2024.08.013","DOIUrl":"10.1016/j.clnesp.2024.08.013","url":null,"abstract":"<div><h3>Background</h3><p>Coffee and tea are considered to have some effects on the risk of glioma as one of the most prevalent intracranial malignant tumors in adults. However, the precise effect of coffee and tea consumption on glioma is not obvious. This umbrella review aimed to evaluate the impact of tea and coffee consumption on glioma risk.</p></div><div><h3>Methods</h3><p>Three online databases containing Scopus, Web of Science, and PubMed were thoroughly searched from the beginning to February 23, 2024 with no language constraints. Relying on I² and Q statistics, a random-effect model or a fixed-effect model was applied. The PICO structure was followed as Population (Patients with glioma), Intervention (Coffee and tea consumption), Comparison (Standard treatment or placebo), and Outcome (Risk of glioma).</p></div><div><h3>Results</h3><p>Totally, seven meta-analyses and systematic reviews contain 23,591 patients were included in this umbrella review. Coffee and tea consumption led to significant 15% and 16% reductions in glioma risk, respectively (RR = 0.85; 95% CI: 0.74, 0.98; RR = 0.84; 95% CI: 0.79, 0.89). The results did not change after subgroup analyses.</p></div><div><h3>Conclusion</h3><p>This umbrella review revealed that the coffee and tea consumption may decrease the glioma risk. Consumption of tea and coffee may be considered as dietary strategies against glioma.</p></div><div><h3>PROSPERO registration code</h3><p>CRD42024521525.</p></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"64 ","pages":"Pages 37-43"},"PeriodicalIF":2.9,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142046379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}