{"title":"Holmium lithotripsy laser-assisted endoscopic retrieval of a fish bone impacted in the esophagus: a rare extraction technique.","authors":"Sarthak Chakrabarti, Sourish Kumar Roy, Rajat Khandelwal, Nikhil Sonthalia, Uday Chand Ghoshal, Mahesh Kumar Goenka","doi":"10.5946/ce.2026.145","DOIUrl":"https://doi.org/10.5946/ce.2026.145","url":null,"abstract":"","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148663617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2026-07-01Epub Date: 2026-07-29DOI: 10.5946/ce.2025.253
Ah Young Lee, Seong Hwan Kim, Joo Young Cho
{"title":"Treatment procedures for intractable gastroesophageal reflux disease after peroral endoscopic myotomy for achalasia: a retrospective study in South Korea.","authors":"Ah Young Lee, Seong Hwan Kim, Joo Young Cho","doi":"10.5946/ce.2025.253","DOIUrl":"10.5946/ce.2025.253","url":null,"abstract":"<p><strong>Background: </strong>No study has compared the safety and efficacy of anti-reflux mucosal ablation (ARMA), anti-reflux mucosectomy (ARMS), and Stretta radiofrequency (SRF) for intractable gastroesophageal reflux disease (GERD) after peroral endoscopic myotomy (POEM).</p><p><strong>Methods: </strong>Twenty-two patients with post-POEM GERD underwent either ARMA (n=12), ARMS (n=6), or SRF (n=4). GERD questionnaire (GERDQ) score, endoscopic Los Angeles classification, flap valve grade based on Hill's type EndoFLIP distensibility index (DI), and rate of proton pump inhibitor withdrawal were analyzed and compared. The factors associated with the occurrence of post-POEM intractable GERD were also evaluated.</p><p><strong>Results: </strong>The ARMS group demonstrated a significant improvement in GERDQ scores after 6 months of follow-up (p=0.04). No significant differences were observed in the endoscopic Los Angeles grade (p=0.68), flap valve grade (p=0.38), or EndoFLIP DI (p=0.15). Type III achalasia and posterior myotomy orientation during POEM were identified as risk factors for reintervention. Postprocedural adverse events (bleeding and stricture) occurred in the ARMA and ARMS groups.</p><p><strong>Conclusions: </strong>Among the three procedures, ARMS produced the most notable improvement in symptoms, whereas endoscopic esophagitis and EndoFLIP DI did not show a similar improvement.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":"59 4","pages":"612-621"},"PeriodicalIF":3.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13439303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148673101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Non-variceal upper gastrointestinal bleeding: advances and future directions in management.","authors":"Waku Hatta, Yohei Ogata, Takashi Chiba, Naotaro Tanno, Makoto Kawabe, Kimiko Kayada, Yutaka Hatayama, Masahiro Saito, Akira Imatani, Tomoyuki Koike, Atsushi Masamune","doi":"10.5946/ce.2025.202","DOIUrl":"10.5946/ce.2025.202","url":null,"abstract":"<p><p>Numerous clinical guidelines have been developed for the management of non-variceal upper gastrointestinal bleeding (NVUGIB), yet significant variations exist among the recommendations. This review summarizes the most recent evidence on NVUGIB management, structured across four key stages: pre-endoscopic management, endoscopic treatment, post-endoscopic care, and the identification and management of refractory bleeding. In the pre-endoscopic phase, several risk-scoring systems have been developed to predict mortality. A restrictive transfusion strategy, with a threshold of 7 to 8 g/dL, is now recommended for most patients. Pre-endoscopic administration of intravenous erythromycin also improves visualization during endoscopy. A wide array of endoscopic hemostasis techniques is available, with the choice of method depending on the underlying cause of bleeding. When endoscopic hemostasis fails, transcatheter arterial embolization (TAE) is generally preferred over surgery as the second-line intervention. Once hemostasis is achieved, high-dose acid suppression is essential, and the risk of rebleeding should be assessed. For patients who experience rebleeding, repeat endoscopic therapy is recommended as the first-line approach. However, determining the optimal timing for TAE remains a challenge. Because of the heterogeneity of clinical presentations, NVUGIB management should be personalized. Further research is needed to establish evidence-based, individualized treatment strategies.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"510-522"},"PeriodicalIF":3.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13439290/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145773827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2026-07-01Epub Date: 2026-07-30DOI: 10.5946/ce.2026.022
Chen-Ya Kuo, David Karsenti, Salvador Machlab, Fu-Jen Lee, Yu-Tsung Chen, Te-Ling Ma, Chi-Yang Chang, Yu-Tse Chiu
{"title":"To what extent can bowel preparation quality be considered \"adequate\"?: a systematic review and meta-analysis.","authors":"Chen-Ya Kuo, David Karsenti, Salvador Machlab, Fu-Jen Lee, Yu-Tsung Chen, Te-Ling Ma, Chi-Yang Chang, Yu-Tse Chiu","doi":"10.5946/ce.2026.022","DOIUrl":"10.5946/ce.2026.022","url":null,"abstract":"<p><strong>Background: </strong>While low-quality bowel preparation is known to reduce the adenoma detection rate (ADR), the distinction between intermediate- and high-quality preparations remains unclear.</p><p><strong>Methods: </strong>Electronic searches were conducted in PubMed and Embase through July 2024. Randomized controlled trials reporting ADR and the Boston bowel preparation scale (BBPS) were included, and outcomes were pooled according to bowel preparation quality using a random-effects model. The primary outcome was ADR in intermediate-quality (BBPS ≥6, and ≥2 in each segment) versus high-quality (BBPS≥8) bowel preparation. Secondary outcomes included advanced ADR.</p><p><strong>Results: </strong>Fourteen trials were included (5,246 in the high-quality group and 1,728 in the other group). There was no significant difference in ADR (risk difference [RD], -0.02; p=0.13; I2=21%). Subgroup analyses showed no significant difference with computer-aided detection (CADe; RD, -0.03; p=0.70; I2=81%) or linked color imaging (RD, 0.04; p=0.31; I2=0%). The heterogeneity observed with CADe may reflect differences in colonoscopist experience or CADe systems. The results were similar for advanced ADR. Funnel plot and Egger's test indicated minimal publication bias.</p><p><strong>Conclusions: </strong>Intermediate-quality preparation allows adequate adenoma detection. When each BBPS subscore is ≥2, surveillance recommendations can generally be followed.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":"59 4","pages":"569-580"},"PeriodicalIF":3.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13439292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148673126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2026-07-01Epub Date: 2026-02-13DOI: 10.5946/ce.2025.260
Sang Pyo Lee, Shin Hee Kim
{"title":"Role of image-enhanced endoscopy for the diagnosis of gastric intestinal metaplasia.","authors":"Sang Pyo Lee, Shin Hee Kim","doi":"10.5946/ce.2025.260","DOIUrl":"10.5946/ce.2025.260","url":null,"abstract":"<p><p>Gastric intestinal metaplasia (IM) is a key precursor lesion in gastric cancer progression, as described by the Correa model. Image-enhanced endoscopy (IEE) with magnifying endoscopy has significantly improved the visualization of the mucosal surfaces and microvascular structures, aiding in the accurate diagnosis of IM. While histological evaluation remains the gold standard, IEE might provide a practical and cost-effective alternative for the risk stratification of gastric IM.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"523-528"},"PeriodicalIF":3.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13439288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147644551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2026-07-01Epub Date: 2026-07-29DOI: 10.5946/ce.2024.099.c
Mark Ly, Ngee-Soon Lau, Joanna Huang, Hayden Ly, Kasper Ewenson, Nicole Mestrovic, Paul Yousif, Ken Liu, Avik Majumdar, Geoffrey McCaughan, Michael Crawford, Carlo Pulitano
{"title":"Corrigendum: Ex vivo cholangioscopy in liver grafts: a novel technique and an experimental non-clinical study to assess the biliary tree during organ preservation and machine perfusion.","authors":"Mark Ly, Ngee-Soon Lau, Joanna Huang, Hayden Ly, Kasper Ewenson, Nicole Mestrovic, Paul Yousif, Ken Liu, Avik Majumdar, Geoffrey McCaughan, Michael Crawford, Carlo Pulitano","doi":"10.5946/ce.2024.099.c","DOIUrl":"10.5946/ce.2024.099.c","url":null,"abstract":"","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":"59 4","pages":"687"},"PeriodicalIF":3.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13446077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148672990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2026-07-01Epub Date: 2026-04-28DOI: 10.5946/ce.2025.214
Koichi Soga, Ikuhiro Kobori, Masaya Tamano
{"title":"Recanalization of complete hepaticojejunostomy stricture via delayed fistula formation after direct needle puncture: a video case report.","authors":"Koichi Soga, Ikuhiro Kobori, Masaya Tamano","doi":"10.5946/ce.2025.214","DOIUrl":"10.5946/ce.2025.214","url":null,"abstract":"","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"667-668"},"PeriodicalIF":3.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13444531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2026-07-01Epub Date: 2026-07-29DOI: 10.5946/ce.2026.206
Ji Yong Ahn
{"title":"Gastric cancer suspected on endoscopy at a referring hospital.","authors":"Ji Yong Ahn","doi":"10.5946/ce.2026.206","DOIUrl":"10.5946/ce.2026.206","url":null,"abstract":"","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":"59 4","pages":"680-682"},"PeriodicalIF":3.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13439300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148673103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2026-07-01Epub Date: 2026-06-10DOI: 10.5946/ce.2025.401
Giel J L van Neerven, Eline H T Gilissen, Roos Gielen, Arlinda Baars, Bianca M L Stelten, Hajo Flink, Lennard P L Gilissen
{"title":"Percutaneous endoscopic gastrostomy with jejunal extension versus direct percutaneous endoscopic jejunostomy: patient-related outcomes and complications.","authors":"Giel J L van Neerven, Eline H T Gilissen, Roos Gielen, Arlinda Baars, Bianca M L Stelten, Hajo Flink, Lennard P L Gilissen","doi":"10.5946/ce.2025.401","DOIUrl":"10.5946/ce.2025.401","url":null,"abstract":"<p><strong>Background: </strong>Percutaneous endoscopic gastrostomy with jejunal extension (PEG-J) and direct percutaneous endoscopic jejunostomy (D-PEJ) are used for jejunal feeding or administration of levodopa-carbidopa intestinal gel in patients with Parkinson's disease. PEG-J is currently preferred because it is technically less challenging to insert. However, comparative studies are scarce, and data on patient-reported outcomes (PROMs) are limited.</p><p><strong>Methods: </strong>In this retrospective study conducted at a referral hospital, clinical experience, adverse events (AEs), and PROMs associated with both techniques were evaluated.</p><p><strong>Results: </strong>Ninety-three patients underwent PEG-J and/or D-PEJ placement between January 1, 2010, and July 1, 2022. Patients with PEG-J required significantly more re-endoscopies per tube-year than those with D-PEJ (0.63 [standard deviation, SD, 0.72] vs. 0.27 [SD 0.50]). A total of 76.8% of PEG-J patients underwent at least one re-endoscopy (range, 0-3.85 per year), primarily due to dislocated jejunal extensions (77.4%). Tube-related AEs (including dislocation, occlusion, perforation, and ulceration) occurred significantly more often after PEG-J insertion (76.7% vs. 25.9%). Forty-five patients (48%) completed the PROM questionnaire. No statistically significant differences were found in quality of life. However, D-PEJ patients reported significantly more tube-related pain (44.4% vs. 15.9%).</p><p><strong>Conclusions: </strong>D-PEJ represents a viable alternative to PEG-J in experienced centers and should be considered when frequent complications with jejunal extensions occur.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"642-652"},"PeriodicalIF":3.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13439301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148223387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}