{"title":"Recanalization of complete hepaticojejunostomy stricture via delayed fistula formation after direct needle puncture: a video case report.","authors":"Koichi Soga, Ikuhiro Kobori, Masaya Tamano","doi":"10.5946/ce.2025.214","DOIUrl":"https://doi.org/10.5946/ce.2025.214","url":null,"abstract":"","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raquel Gonçalves, Joel Silva, Eduardo Rodrigues-Pinto
{"title":"Latest advancements in endoscopic palliative care for patients with pancreatic cancer.","authors":"Raquel Gonçalves, Joel Silva, Eduardo Rodrigues-Pinto","doi":"10.5946/ce.2025.227","DOIUrl":"https://doi.org/10.5946/ce.2025.227","url":null,"abstract":"<p><p>Pancreatic cancer is a major cause of cancer-related mortality and is frequently diagnosed at advanced stages when surgery is no longer an option. Most patients require palliative care to manage symptoms, such as jaundice, pain, and gastric outlet obstruction (GOO). Therapeutic endoscopic options, including endoscopic ultrasound (EUS)-guided techniques, have become essential for improving quality of life. We conducted a literature review focusing on the current palliative endoscopic therapy options for advanced pancreatic cancer. Malignant biliary obstruction is primarily treated using endoscopic retrograde cholangiopancreatography. However, when this method is complex or unsuccessful, EUS-guided biliary drainage is considered a reliable and safe alternative. Irradiating stents may increase stent patency times and patient survival. EUS-guided gastroenterostomy, if technical expertise is available, is becoming the first option for GOO in patients with longer survival, with enteral stenting being preferred for patients with limited life expectancies or when the EUS option is not available. Although EUS-guided celiac plexus neurolysis and pancreatic duct drainage play a role in pain management, EUS-guided radiofrequency ablation remains under investigation. In conclusion, endoscopic and EUS-guided interventions provide safe, minimally invasive, and highly effective approaches for the palliative care of pancreatic cancer, enhancing patients' quality of life and minimizing the need for more invasive surgical procedures.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Veghova Velganova, Martin Stasek, Eva Karaskova, Jana Volejnikova
{"title":"Large pseudopolyp of appendiceal stump treated by endoscopic loop ligation \"loop-and-let-go\" in two pediatric cases.","authors":"Maria Veghova Velganova, Martin Stasek, Eva Karaskova, Jana Volejnikova","doi":"10.5946/ce.2025.448","DOIUrl":"https://doi.org/10.5946/ce.2025.448","url":null,"abstract":"","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Edgardo Amaya-Fragoso, José Guillermo de la Mora-Levy, Uriel Isaías Martín-Flores
{"title":"Echoendoscopic evaluation of the vascular pattern of solid pancreatic lesions as a predictor of neuroendocrine neoplasms: a retrospective study in Mexico.","authors":"Edgardo Amaya-Fragoso, José Guillermo de la Mora-Levy, Uriel Isaías Martín-Flores","doi":"10.5946/ce.2025.338","DOIUrl":"https://doi.org/10.5946/ce.2025.338","url":null,"abstract":"<p><strong>Background/aims: </strong>Endoscopic ultrasonography (EUS) is essential for evaluating solid pancreatic lesions (SPL). Pancreatic neuroendocrine neoplasms (pNEN) account for 2% of SPL and typically show hypervascularity. This study aimed to assess whether a specific vascular pattern could predict pNEN.</p><p><strong>Methods: </strong>Patients who underwent EUS for a SPL and were histologically diagnosed with pNEN were included. Tissues were obtained using endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) and/or surgical resection. Power Doppler was used to assess the vascular patterns. Patients with pNEN were compared to those diagnosed with pancreatic ductal adenocarcinoma during the same period. Group comparisons by size and histological grade were performed using the chi-square test. Logistic regression analysis identified the EUS features associated with pNEN.</p><p><strong>Results: </strong>Among 125 patients (43 pNEN), a peripheral vascular rim (PVR) was associated with pNEN (odds ratio [OR], 2.8; 95% confidence interval [CI], 1.7-8.5; p=0.03), with 100% specificity. Hypervascularity (OR, 3.8; 95% CI, 1.1-13.4; p=0.03) and pancreatic atrophy (OR, 0.3; 95% CI, 0.1-0.9; p=0.04) were also associated.</p><p><strong>Conclusions: </strong>PVR demonstrated 100% specificity and 34.9% sensitivity for pNEN diagnosis, serving as a rule-in sign. PVR visualization may aid in differential diagnosis when EUS-FNB is unavailable or inconclusive.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A pilot study of a novel tapered and flared fully covered self-expandable metal stent for unresectable malignant distal biliary obstruction: a multicenter study in Japan.","authors":"Toji Murabayashi, Makoto Kobayashi, Keisuke Iwata, Yuhei Iwasa, Yujiro Kawakami, Yoshiharu Masaki, Shinya Kawaguchi, Hayato Nakagawa","doi":"10.5946/ce.2025.399","DOIUrl":"https://doi.org/10.5946/ce.2025.399","url":null,"abstract":"<p><strong>Background/aims: </strong>This study evaluated the feasibility and clinical outcomes of a novel tapered and flared, fully covered, self-expandable metal stent (TF-FCSEMS) for unresectable malignant distal biliary obstruction (UMDBO).</p><p><strong>Methods: </strong>This multicenter retrospective study included 40 patients who underwent transpapillary placement of a TF-FCSEMS (10-mm cylindrical body with an 8-mm tapered distal end) for UMDBO between May 2023 and July 2024. The primary outcome was time to recurrent biliary obstruction (TRBO). Secondary outcomes included technical and clinical successes, adverse events (AEs), and overall survival.</p><p><strong>Results: </strong>Technical and clinical success rates were 100% and 98%, respectively. During a median follow-up period of 271 days, recurrent biliary obstruction (RBO) occurred in 10 (26%) patients. The median TRBO was 539 days (95% confidence interval, 389-not reached), and the non-RBO rates at 3, 6, and 12 months were 94%, 71%, and 61%, respectively. During a median follow-up period of 271 days, recurrent biliary obstruction (RBO) occurred in 10 (26%) of the 39 patients who achieved clinical success. Post-endoscopic retrograde cholangiopancreatography pancreatitis occurred in four patients (10%). Non-occlusion cholangitis developed in five (13%) patients, mostly with tumor-related duodenal stenosis. All AEs were managed conservatively or endoscopically.</p><p><strong>Conclusions: </strong>TF-FCSEMS appears to be a feasible and acceptable treatment option for UMDBO. Further prospective studies are required to confirm these findings.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hwijun Lee, Huynh Cong Bang, Seokho Cho, Jungmin Ha, Tran Thien Khiem, Le Viet Tung, La Vinh Phuc, Duong Trong Si, Tran The Du, Diem Thi-Ngoc Vo, Vo Nguyen Trung
{"title":"Impact of real-time artificial intelligence integration on detection of gastric lesions: an exploratory single-center before-and-after study using low-definition routine endoscopy.","authors":"Hwijun Lee, Huynh Cong Bang, Seokho Cho, Jungmin Ha, Tran Thien Khiem, Le Viet Tung, La Vinh Phuc, Duong Trong Si, Tran The Du, Diem Thi-Ngoc Vo, Vo Nguyen Trung","doi":"10.5946/ce.2025.272","DOIUrl":"https://doi.org/10.5946/ce.2025.272","url":null,"abstract":"<p><strong>Background/aims: </strong>Early detection of gastric neoplasia, particularly subcentimeter lesions, using upper gastrointestinal (GI) endoscopy remains challenging. This study evaluated the impact of a real-time artificial intelligence (AI) detection system on the lesion detection rate (LDR) during routine upper GI endoscopy performed using a low-definition platform commonly used in resource-limited settings, with a focus on lesions ≤0.5 cm.</p><p><strong>Methods: </strong>Diagnostic upper GI endoscopies performed between September 2024 and May 2025 were analyzed. LDRs were compared between the pre- and post-AI periods, including subgroup analyses by lesion size and type.</p><p><strong>Results: </strong>A total of 2,329 patients were included (1,491 pre-AI, 838 post-AI). After AI implementation, overall LDR per person increased from 1.15±0.45 to 1.20±0.57 (p<0.05). Detection of lesions ≤0.5 cm increased from 18.0% to 19.8% (p<0.05), while detection of larger lesions remained unchanged. The biopsy rate decreased from 13.8% to 8.5% (p<0.05).</p><p><strong>Conclusions: </strong>Real-time AI modestly improved the detection of diminutive gastric lesions while reducing unnecessary biopsies without compromising malignancy detection, thereby supporting its utility in routine endoscopy under resource-limited conditions.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jae Hyun Kim, Seung-Joo Nam, Beom Jae Lee, Eun Ran Kim, Eun Sun Kim, Eun Soo Kim, Chang Kyun Lee, Yehyun Park, Geom Seog Seo, Jong-Jae Park, Hyun-Soo Kim
{"title":"Korean clinical practice guidelines for bowel preparation before colonoscopy.","authors":"Jae Hyun Kim, Seung-Joo Nam, Beom Jae Lee, Eun Ran Kim, Eun Sun Kim, Eun Soo Kim, Chang Kyun Lee, Yehyun Park, Geom Seog Seo, Jong-Jae Park, Hyun-Soo Kim","doi":"10.5946/ce.2026.053","DOIUrl":"https://doi.org/10.5946/ce.2026.053","url":null,"abstract":"<p><p>Appropriate bowel cleansing is essential for successful and safe colonoscopy. Inadequate bowel cleansing can lead to poor visualization of the delicate mucosa, leading to missed precancerous lesions, increased risk of procedure-related complications, and increased medical costs due to re-examination. Several types of bowel cleansing agents that improve ease of administration have been developed in recent years, and the clinical outcomes have been published. Bowel cleansing efficiency can differ between races due to differences in socio-environmental factors, including dietary patterns. This paper is the first Korean clinical guideline for bowel preparation for colonoscopy, formulated by the Korean Society of Gastrointestinal Endoscopy. These guidelines were developed using adaptation methods and the findings of studies on Korean patients; recently published studies were considered to the extent possible. These guidelines will be revised as and when new data regarding bowel preparation are accumulated.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Seeing more by looking longer: the value of time in diagnostic upper endoscopy.","authors":"Seung Young Seo","doi":"10.5946/ce.2026.025","DOIUrl":"https://doi.org/10.5946/ce.2026.025","url":null,"abstract":"","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful endoscopic removal of a hard rectal fecaloma using a needle-type knife and snare.","authors":"Sukit Pattarajierapan, Papanun Methakittrakoon, Thitithep Limvorapitak, Prapon Kanjanasilp, Supakij Khomvilai","doi":"10.5946/ce.2026.046","DOIUrl":"https://doi.org/10.5946/ce.2026.046","url":null,"abstract":"","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147644653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}