{"title":"Advancements in stent strategies for malignant distal biliary obstruction: defining the clinical role of multi-hole self-expandable metal stents.","authors":"Sung Yong Han","doi":"10.5946/ce.2025.210","DOIUrl":"10.5946/ce.2025.210","url":null,"abstract":"","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"698-700"},"PeriodicalIF":2.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2025-09-01Epub Date: 2025-05-08DOI: 10.5946/ce.2024.349
Younghun Jeon, Hoonsub So, Sung Jo Bang
{"title":"Role of fully covered metal stents in the management of chronic pancreatitis.","authors":"Younghun Jeon, Hoonsub So, Sung Jo Bang","doi":"10.5946/ce.2024.349","DOIUrl":"10.5946/ce.2024.349","url":null,"abstract":"<p><p>Chronic pancreatitis (CP), a progressive inflammatory disease that results in irreversible pancreatic damage, is often complicated by ductal strictures and debilitating pain. Fully covered self-expandable metal stents (FCSEMS) have emerged as significant innovations in the endoscopic management of refractory pancreatic duct strictures. This review synthesizes recent evidence highlighting the benefits and limitations of FCSEMS, such as superior patency, reduced need for reinterventions, and effective symptom relief compared to traditional plastic stents, alongside risks, such as stent migration and de novo strictures. A comparison with plastic stents and an algorithm for pancreatic duct stricture management are provided. Regional variations in clinical guidelines from the United States, Europe, Japan, and Korea reflect diverse approaches to integrating FCSEMS into practice. Emerging innovations in stent technology are promising for improving CP management outcomes.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"646-652"},"PeriodicalIF":2.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2025-09-01Epub Date: 2025-07-04DOI: 10.5946/ce.2024.347
David Novotny, Jan Palenik, Tomas Tyll, Nadija Brodyuk, Stepan Suchanek, Michal Sotak
{"title":"Impact of opioid addition on procedural conditions during colonoscopy: a randomized trial comparing propofol-based sedation protocols.","authors":"David Novotny, Jan Palenik, Tomas Tyll, Nadija Brodyuk, Stepan Suchanek, Michal Sotak","doi":"10.5946/ce.2024.347","DOIUrl":"10.5946/ce.2024.347","url":null,"abstract":"<p><strong>Background: </strong>Propofol is the most effective sedative for colonoscopy; however, opioids do have several adverse effects that need to be discussed. The objective of this study was to compare the ease of colonoscopy during propofol-based sedation with and without fentanyl, while closely monitoring ventilatory data and the safety of the procedure.</p><p><strong>Methods: </strong>This prospective single-center trial randomized 50 patients who underwent minor colonoscopies. The propofol group received sedation exclusively via propofol, whereas the propofol+fentanyl group was premedicated with 1 µg/kg fentanyl. Patients were monitored using a bioimpedance ventilatory monitor, and both the patients and endoscopists were questioned regarding their level of satisfaction.</p><p><strong>Results: </strong>The endoscopists reported a higher level of ease with the colonoscopy procedure (mean on a 5-point scale, 1.2 vs. 1.72; p=0.028) and the overall patient satisfaction score was higher (1.15 vs. 1.28, p=0.026) in the propofol+fentanyl group. No significant differences were observed in the ventilatory parameters between the groups. No major adverse events were reported in any of the groups.</p><p><strong>Conclusions: </strong>The inclusion of fentanyl leads to enhanced levels of satisfaction for both the endoscopist and the patient, without any impact on ventilation and safety. The use of bioimpedance monitoring of ventilation during colonoscopy is a suitable approach that may enhance the safety of procedural sedation.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"722-730"},"PeriodicalIF":2.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144559400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2025-09-01Epub Date: 2025-08-29DOI: 10.5946/ce.2025.200
Kyong Joo Lee, Se Woo Park
{"title":"Refining the diagnostic strategy for malignant lymphoma: advantages of endoscopic ultrasound-guided fine-needle biopsy over aspiration.","authors":"Kyong Joo Lee, Se Woo Park","doi":"10.5946/ce.2025.200","DOIUrl":"10.5946/ce.2025.200","url":null,"abstract":"","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"701-702"},"PeriodicalIF":2.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk factors for suspected infectious fever after diagnostic upper endoscopy: propofol overdose in a retrospective study from Korea.","authors":"Sunmin Lee, Jung-Hwan Lee, Jongbeom Shin, Boram Cha, Ji-Taek Hong, Kye Sook Kwon","doi":"10.5946/ce.2024.348","DOIUrl":"10.5946/ce.2024.348","url":null,"abstract":"<p><strong>Background: </strong>Propofol is widely used for sedation during upper endoscopy; however, oversedation may increase the risk of complications, including aspiration pneumonia. This study aimed to determine whether propofol overdose is a risk factor for suspected postendoscopic infectious fever (SPIF).</p><p><strong>Methods: </strong>We retrospectively analyzed 1,474 in-patients who underwent upper endoscopy at Inha University Hospital between October 2021 and October 2022. After excluding 400 patients who received interventional procedures, SPIF was defined as new-onset fever (≥38 °C) within three days post-endoscopy with at least one of the following: intravenous antibiotic initiation, leukocytosis (white blood cell≥10,000/mm³), positive blood or sputum cultures, or pneumonia on chest X-ray. The risk factors assessed included comorbidities, sedative type and dosage, procedure duration, and endoscopist's experience.</p><p><strong>Results: </strong>New-onset fever occurred in 40 patients (3.7%), with 20 (1.9%) meeting SPIF criteria. Multivariable analysis showed propofol overdose (>2.2 mg/kg) significantly increased risks of new-onset fever (odds ratio [OR], 1.03; 95% confidence interval [CI], 1.00-1.06; p=0.023) and SPIF (OR, 1.04; 95% CI, 1.00-1.04; p=0.034). Dementia (OR, 1.11, p<0.001) and prolonged procedure (>5 minutes; OR, 1.01; p=0.012) were also risk factors for SPIF.</p><p><strong>Conclusions: </strong>Propofol overdose significantly increases the risk of SPIF. Careful sedation management is essential, especially for patients with dementia or prolonged procedures.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":"58 5","pages":"703-711"},"PeriodicalIF":2.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2025-09-01Epub Date: 2025-07-30DOI: 10.5946/ce.2024.294
Rabbinu Rangga Pribadi, Ahmad Fariz Malvi Zamzam Zein, Raisa Wibowo, Achmad Fauzi, Abdul Aziz Rani, Marcellus Simadibrata, Dadang Makmun, Murdani Abdullah, Ari Fahrial Syam, Muhammad Miftahussurur, Agasjtya Wisjnu Wardhana, Amanda Pitarini Utari, Andi Muhammad Luthfi Parewangi, Arles Arles, Arnelis Arnelis, Bradley Jimmy Waleleng, Bogi Pratomo Wibowo, Fauzi Yusuf, Hasan Maulahela, Hery Djagat Purnomo, I Dewa Nyoman Wibawa, Ignatia Sinta Murti, Indra Marki, Kaka Renaldi, Masrul Lubis, Muhammad Begawan Bestari, Muhammad Firhat Idrus, Pieter Saragih, Putut Bayupurnama, Ruswhandi Ruswhandi, Saskia Aziza Nursyirwan, Suyata Suyata, Titong Sugihartono, Triyanta Yuli Pramana, Virly Nanda Muzellina, Yustar Mulyadi
{"title":"Best practice of gastrointestinal endoscopy during Mpox upsurge: an Indonesian Society for Digestive Endoscopy recommendation.","authors":"Rabbinu Rangga Pribadi, Ahmad Fariz Malvi Zamzam Zein, Raisa Wibowo, Achmad Fauzi, Abdul Aziz Rani, Marcellus Simadibrata, Dadang Makmun, Murdani Abdullah, Ari Fahrial Syam, Muhammad Miftahussurur, Agasjtya Wisjnu Wardhana, Amanda Pitarini Utari, Andi Muhammad Luthfi Parewangi, Arles Arles, Arnelis Arnelis, Bradley Jimmy Waleleng, Bogi Pratomo Wibowo, Fauzi Yusuf, Hasan Maulahela, Hery Djagat Purnomo, I Dewa Nyoman Wibawa, Ignatia Sinta Murti, Indra Marki, Kaka Renaldi, Masrul Lubis, Muhammad Begawan Bestari, Muhammad Firhat Idrus, Pieter Saragih, Putut Bayupurnama, Ruswhandi Ruswhandi, Saskia Aziza Nursyirwan, Suyata Suyata, Titong Sugihartono, Triyanta Yuli Pramana, Virly Nanda Muzellina, Yustar Mulyadi","doi":"10.5946/ce.2024.294","DOIUrl":"10.5946/ce.2024.294","url":null,"abstract":"<p><p>The emergence of Mpox as a significant zoonotic viral threat presents new challenges in gastrointestinal endoscopy. This article outlines the risk of Mpox transmission during gastrointestinal endoscopy, particularly through respiratory droplets and contact with the mucosal surfaces. Gastrointestinal endoscopy may also facilitate transmission by fomites, as the Mpox virus can persist on medical instruments and surfaces for long periods. Nosocomial Mpox transmission is a significant concern in both endemic and non-endemic regions. This highlights the necessity for enhanced infection control measures in gastrointestinal endoscopy, including pre-endoscopic assessment, proper use of personal protective equipment, and rigorous post-procedural disinfection. Additionally, vaccination of healthcare workers frequently exposed to high-risk situations is emphasized. Ongoing surveillance and monitoring of healthcare workers are key components in minimizing the transmission risk. Although no direct cases of Mpox transmission via gastrointestinal endoscopy have been reported, these recommendations mitigate the potential risks associated with such procedures and necessitate strict adherence to infection control protocols. By adhering to these protocols and adapting to current practices, gastrointestinal endoscopy can be safely performed during the Mpox upsurge, ensuring the protection of both patients and healthcare workers.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"662-669"},"PeriodicalIF":2.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144741338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}