Clinical EndoscopyPub Date : 2025-05-01Epub Date: 2025-03-28DOI: 10.5946/ce.2024.245
Ah Young Lee, Joo Young Cho
{"title":"Peroral endoscopic myotomy for achalasia combined with esophageal varices.","authors":"Ah Young Lee, Joo Young Cho","doi":"10.5946/ce.2024.245","DOIUrl":"10.5946/ce.2024.245","url":null,"abstract":"","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"490-492"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12138353/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2025-05-01Epub Date: 2025-05-19DOI: 10.5946/ce.2024.306
Yuki Tanisaka, Robert Hawes
{"title":"Peroral cholangioscopy: past, present and future.","authors":"Yuki Tanisaka, Robert Hawes","doi":"10.5946/ce.2024.306","DOIUrl":"10.5946/ce.2024.306","url":null,"abstract":"<p><p>Endoscopic retrograde cholangiopancreatography (ERCP) is the gold standard for the evaluation of biliary strictures and the management of bile duct stones. However, standard ERCP techniques sometimes fail for both indications. In such situations, peroral cholangioscopy (POCS), which allows direct visualization of the bile duct, can play a significant role in diagnosis and treatment. Direct visualization using POCS can help differentiate between malignant and benign conditions and is more accurate in defining the extent of cholangiocarcinoma. Furthermore, POCS enables visually guided biopsies. Certain types of difficult bile duct stones, such as impacted and intrahepatic stones, require POCS for visually guided lithotripsy. Recent advancements in POCS will broaden its applicability and improve its diagnostic utility. In this review, we provide perspectives on the past, present, and future of POCS.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"360-369"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12138359/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2025-05-01Epub Date: 2025-01-14DOI: 10.5946/ce.2024.026
Jae Min Lee, Yehyun Park, Dong Won Ahn, Jun Kyu Lee, Kwang Hyuck Lee
{"title":"Remimazolam, a novel drug, for safe and effective endoscopic sedation.","authors":"Jae Min Lee, Yehyun Park, Dong Won Ahn, Jun Kyu Lee, Kwang Hyuck Lee","doi":"10.5946/ce.2024.026","DOIUrl":"10.5946/ce.2024.026","url":null,"abstract":"<p><p>Remimazolam is a novel benzodiazepine with unique pharmacokinetic and pharmacodynamic properties, making it an ideal candidate for sedation during endoscopic procedures. Distinguished by its rapid onset and short duration of action, remimazolam offers a safer and more efficient alternative to traditional sedatives, such as midazolam and propofol, with fewer side effects, such as hypotension, bradycardia, and respiratory depression. This article reviews the characteristics of remimazolam and its practical advantages, including ease of use, quick recovery time, and minimal residual sedation, emphasizing its potential to improve patient safety and procedural efficiency in clinical endoscopy settings.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"370-376"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12138356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142976852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2025-05-01Epub Date: 2025-05-08DOI: 10.5946/ce.2025.099
Yuto Shimamura
{"title":"Redefining endoscopic management of refractory gastroesophageal reflux disease: the role of Stretta radiofrequency therapy and antireflux mucosectomy.","authors":"Yuto Shimamura","doi":"10.5946/ce.2025.099","DOIUrl":"10.5946/ce.2025.099","url":null,"abstract":"","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"398-400"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12138367/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2025-05-01Epub Date: 2025-03-25DOI: 10.5946/ce.2024.274
Chen-Shuan Chung, Hua-Fen Chen, Jiann-Ming Wu
{"title":"Endoscopic sleeve gastroplasty combined with anti-obesity medication for better control of weight and diabetes.","authors":"Chen-Shuan Chung, Hua-Fen Chen, Jiann-Ming Wu","doi":"10.5946/ce.2024.274","DOIUrl":"10.5946/ce.2024.274","url":null,"abstract":"","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"478-481"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12138350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2025-05-01Epub Date: 2025-05-09DOI: 10.5946/ce.2024.155
Spyros Peppas, Advait Suvarnakar, Bara A Abujaber, Nadera Altork, Amer Arman, Sayel Alzraikat, Akram I Ahmad, Camille Boustani, Won Kyoo Cho
{"title":"Endoscopic ultrasound-guided biliary drainage versus endoscopic retrograde cholangiopancreatography biliary drainage in the palliative management of malignant distal biliary obstruction: an updated systematic review and meta-analysis of randomized controlled trials.","authors":"Spyros Peppas, Advait Suvarnakar, Bara A Abujaber, Nadera Altork, Amer Arman, Sayel Alzraikat, Akram I Ahmad, Camille Boustani, Won Kyoo Cho","doi":"10.5946/ce.2024.155","DOIUrl":"10.5946/ce.2024.155","url":null,"abstract":"<p><strong>Background/aims: </strong>Evidence suggests comparable outcomes between endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) in the biliary drainage of malignant distal biliary obstruction (MDBO). We conducted an updated systematic review and meta-analysis comparing the EUS with ERCP in the management of MDBO.</p><p><strong>Methods: </strong>We performed a literature search using the Medline, Embase and Cochrane databases, including randomized controlled trials comparing EUS and ERCP in patients with MDBO. Meta-analysis was performed using the random-effects model using the STATA ver. 17.0 software.</p><p><strong>Results: </strong>Both procedures were comparable in technical (risk ratio [RR], 1.01; 95% confidence interval [CI], 0.78-1.30) and clinical (RR, 1.10; 95% CI, 0.85-1.41) success. No difference was identified in total adverse events (RR, 0.75; 95% CI, 0.42-1.35), acute cholangitis (RR, 0.84; 95% CI, 0.43-1.62), stent patency (RR, 1.13; 95% CI, 0.87-1.46) and mean stent patency time (mean difference, -0.01; 95% CI: -0.21 to 0.19). ERCP was associated with a higher risk of procedure-related pancreatitis (RR, 0.17; 95% CI, 0.04-0.68) and statistically non-significant higher risk for reintervention (RR, 0.61; 95% CI, 0.37-1.01).</p><p><strong>Conclusions: </strong>Although EUS and ERCP were comparable in terms of efficacy and safety, ERCP was associated with a higher risk of procedure-related pancreatitis and reintervention, with the latter finding not reaching statistical significance.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"386-397"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12138357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2025-05-01Epub Date: 2025-04-22DOI: 10.5946/ce.2024.271
Jeong Hoon Kim, Jade Wang, Colton Pence, Patrick Magahis, Enad Dawod, Felice Schnoll-Sussman, Reem Z Sharaiha, David Wan
{"title":"GI Genius increases small and right-sided adenoma and sessile serrated lesion detection rate when used with EndoCuff in a real-world setting: a retrospective United States study.","authors":"Jeong Hoon Kim, Jade Wang, Colton Pence, Patrick Magahis, Enad Dawod, Felice Schnoll-Sussman, Reem Z Sharaiha, David Wan","doi":"10.5946/ce.2024.271","DOIUrl":"10.5946/ce.2024.271","url":null,"abstract":"<p><strong>Background/aims: </strong>The real-world efficacy of computer-aided detection (CADe) systems, such as GI Genius (Medtronic), is unclear. We examined the colonoscopy metrics using CADe alone and with a mucosal exposure device (EndoCuff; Olympus) in a real-world setting.</p><p><strong>Methods: </strong>We retrospectively reviewed screening and surveillance colonoscopies before, during, and after CADe use in a large tertiary care center. Outcomes included the adenomas per colonoscopy (APC), sessile serrated lesions per colonoscopy, adenoma detection rate (ADR), sessile serrated lesion detection rate (SSLDR), advanced ADR, total polyp detection rate, and true histology rate. The ADR and SSLDR were further examined according to size, colon location, and EndoCuff use.</p><p><strong>Results: </strong>A total of 798 colonoscopies were performed, including 386 pre-CADe, 178 CADe, and 234 post-CADe. In cases where CADe was used with the EndoCuff, the 1 to 5 mm ADR increased from 36.3% (pre-CADe) to 52.1% (CADe) (p=0.01). The 1 to 5 mm SSLDR increased from 9.6% (pre-CADe) to 17.1% (CADe) (p=0.02). The right-sided ADR increased from 30.8% (pre-CADe) to 42.7% (CADe) (p=0.03). The right-sided SSLDR increased from 12.3% (pre-CADe) to 24.8% (CADe) (p<0.001). No significant changes were observed when only CADe was used. No differences were found in other outcome measures. Post-CADe metrics returned to pre-CADe levels.</p><p><strong>Conclusions: </strong>GI Genius is useful for identifying small and right-sided polyps only when used with the EndoCuff.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"438-447"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12138363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2025-05-01Epub Date: 2025-05-23DOI: 10.5946/ce.2025.094
Gunn Huh, Tae Jun Song
{"title":"A new era for autoimmune pancreatitis diagnosis: fine-needle biopsy outperforms fine-needle aspiration in endoscopic ultrasound-guided tissue acquisition.","authors":"Gunn Huh, Tae Jun Song","doi":"10.5946/ce.2025.094","DOIUrl":"10.5946/ce.2025.094","url":null,"abstract":"","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"406-408"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12138349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2025-05-01Epub Date: 2025-01-21DOI: 10.5946/ce.2024.209
Ji Hoon Yu, Hyun Tak Lee, Seok Ki Jang, Ah Young Lee, Jun-Young Seo
{"title":"Influence of sarcopenia on clinical outcomes in peptic ulcer bleeding: a retrospective single-center analysis in Korea.","authors":"Ji Hoon Yu, Hyun Tak Lee, Seok Ki Jang, Ah Young Lee, Jun-Young Seo","doi":"10.5946/ce.2024.209","DOIUrl":"10.5946/ce.2024.209","url":null,"abstract":"<p><strong>Background/aims: </strong>Peptic ulcer bleeding (PUB) is a major cause of nonvariceal gastrointestinal bleeding. As the older population increases, the prevalence of sarcopenia is also growing. Although sarcopenia influences the prognosis of various diseases, its association with clinical outcomes of PUB remains unknown. Therefore, this study aimed to explore this correlation.</p><p><strong>Methods: </strong>We retrospectively analyzed 2,050 patients who underwent esophagogastroduodenoscopy for suspected gastrointestinal bleeding between January 2014 and December 2021. Patients who underwent computed tomography scans were included for sarcopenia evaluation based on the psoas muscle index, defined as the total psoas area normalized by the square of the height of the patient. Sarcopenia was defined using specific cutoffs: ≤7.3 cm2/m2 and ≤5.1 cm2/m2 for men and women, respectively. The primary outcome measured was the 30-day mortality rate.</p><p><strong>Results: </strong>Out of 358 patients, 149 were diagnosed with sarcopenia. The 30-day mortality rate was significantly higher in patients with sarcopenia than in those without. Multivariate regression analysis revealed significant associations between sarcopenia, a high age, blood tests, and comorbidity score, and administration of inotropic agents with 30-day mortality.</p><p><strong>Conclusions: </strong>Our study showed that the presence of sarcopenia, elevated comorbidity scores, and use of inotropes were associated with higher 30-day mortality rates. Considering that sarcopenia may influence the clinical outcomes in patients with PUB, it is crucial to manage patients with sarcopenia with particular care.</p>","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":"58 3","pages":"425-437"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12138361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical EndoscopyPub Date : 2025-05-01Epub Date: 2025-02-27DOI: 10.5946/ce.2024.233
Yuki Fujii, Kazuyuki Matsumoto, Motoyuki Otsuka
{"title":"Successful removal of a buried lumen-apposing metal stent without complications using pancreatic drainage and a hemostatic agent.","authors":"Yuki Fujii, Kazuyuki Matsumoto, Motoyuki Otsuka","doi":"10.5946/ce.2024.233","DOIUrl":"10.5946/ce.2024.233","url":null,"abstract":"","PeriodicalId":10351,"journal":{"name":"Clinical Endoscopy","volume":" ","pages":"476-477"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12175062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}