The comparative study of Stretta radiofrequency and anti-reflux mucosectomy in the management of intractable gastroesophageal reflux disease: a single-center retrospective study from Korea.

IF 2.1 Q3 GASTROENTEROLOGY & HEPATOLOGY
Ah Young Lee, Ji Woo Choi, Jeong Haeng Heo, Jun Young Chung, Seong Hwan Kim, Joo Young Cho
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引用次数: 0

Abstract

Background/aims: Chronic gastroesophageal reflux disease (GERD) requires symptom relief and treatment of associated conditions. In this study, we aimed to compare anti-reflux mucosectomy (ARMS) and Stretta radiofrequency (SRF) for treating patients with chronic GERD who are unresponsive to proton pump inhibitors (PPIs) and to identify the indications for each procedure.

Methods: Data of patients who underwent ARMS or SRF between March 2021 and April 2023 were analyzed. Changes in GERD questionnaire (GERDQ) scores, endoscopic Los Angeles (LA) grade, flap valve grade (FVG) based on Hill's type, EndoFLIP distensibility index (DI), endoscopic Barrett's epithelium (BE) resolution rate, and PPI withdrawal rate were compared between the two groups.

Results: Improvements in the GERDQ scores and PPI withdrawal rates were similar between the groups. The ARMS group showed significantly better changes in endoscopic LA grade, FVG, and EndoFLIP DI than the SRF group. The complications were more prevalent in the ARMS group than in the SRF group.

Conclusions: The change in endoscopic LA grade before and after the procedure was significantly higher in the ARMS group than in the SRF group. Significant improvements in endoscopic FVG, BE resolution, and EndoFLIP DI were observed only with the ARMS group.

韩国单中心回顾性研究:Stretta射频与抗反流粘膜切除术治疗难治性胃食管反流病的比较研究
背景/目的:慢性胃食管反流病(GERD)需要症状缓解和相关疾病的治疗。在这项研究中,我们旨在比较抗反流粘膜切除术(ARMS)和Stretta射频(SRF)治疗对质子泵抑制剂(PPIs)无反应的慢性胃食管反流患者,并确定每种手术的适应症。方法:分析2021年3月至2023年4月期间接受ARMS或SRF的患者数据。比较两组患者GERD问卷(GERDQ)评分、内镜下洛杉矶(LA)分级、基于Hill's型的瓣瓣分级(FVG)、EndoFLIP扩张指数(DI)、内镜下Barrett上皮(BE)分辨率、PPI停药率的变化。结果:两组间GERDQ评分和PPI停药率的改善相似。ARMS组在内镜下LA分级、FVG和EndoFLIP DI方面的变化明显好于SRF组。ARMS组并发症发生率高于SRF组。结论:ARMS组手术前后内镜下LA等级的变化明显高于SRF组。仅ARMS组在内窥镜FVG、BE分辨率和EndoFLIP DI方面有显著改善。
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来源期刊
Clinical Endoscopy
Clinical Endoscopy GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
4.40
自引率
8.00%
发文量
95
审稿时长
26 weeks
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