Clinical and Experimental Otorhinolaryngology最新文献

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Changes in Revision Cochlear Implantation and Device Failure Profiles 人工耳蜗翻修和设备故障情况的变化
IF 3 3区 医学
Clinical and Experimental Otorhinolaryngology Pub Date : 2023-12-28 DOI: 10.21053/ceo.2023.00010
Bokhyun Song, Subi Oh, Doyun Kim, Young Sang Cho, Il Joon Moon
{"title":"Changes in Revision Cochlear Implantation and Device Failure Profiles","authors":"Bokhyun Song, Subi Oh, Doyun Kim, Young Sang Cho, Il Joon Moon","doi":"10.21053/ceo.2023.00010","DOIUrl":"https://doi.org/10.21053/ceo.2023.00010","url":null,"abstract":"Objective. With rapid innovation in and expanding indications for cochlear implantation (CI), changes in the features of revision CI (RCI) appear to be emerging. This study aims to investigate the changes in RCI profile and discuss their clinical significance. Methods. A retrospective chart review was performed for all CIs performed at a tertiary medical institution between October 2001 and January 2023. The rate and reasons for RCI were evaluated and examined in terms of the manufacturer and device model. The Kaplan-Meier curve was used to examine the cumulative and device survival curves. In addition, the cumulative and device survivals were further analyzed based on age group, time period of primary CI, and manufacturer. Cox proportional hazards model was used to evaluate the association between RCI and manufacturers. Results. Among 1,430 CIs, 73 RCIs were conducted (5.1%). Device failure was the most common cause of RCI (40 of 73 RCIs [54.8%]), with an overall device failure rate of 2.8%, followed by flap-associated problems and migration (9 of 73 RCIs each [12.3%]). Flap retention problem appeared as a new cause in three cases (two CI 632 and one SYNCHRONY 2), and six electrode tip fold-over occurred (four CI 600 series and two CI 500 series). The 10-year overall cumulative and device survival rates were 93.4% and 95.8%, respectively. After excluding the models with recall issues, cumulative (P= 0.010) and device survival curves ( P= 0.001) revealed significant differences by manufacturer.","PeriodicalId":10318,"journal":{"name":"Clinical and Experimental Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139150488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of partial and superficial or total parotidectomies for superficial T1-2 primary parotid cancers 浅表 T1-2 原发性腮腺癌部分切除术与浅表或全腮腺切除术的比较
IF 3 3区 医学
Clinical and Experimental Otorhinolaryngology Pub Date : 2023-12-26 DOI: 10.21053/ceo.2023.00014
Seung Hoon Han, Jihae Lee, Jeong Wook Kang, Heejin Kim, Dong Jin Lee, Jin Hwan Kim, Il Seok Park
{"title":"Comparison of partial and superficial or total parotidectomies for superficial T1-2 primary parotid cancers","authors":"Seung Hoon Han, Jihae Lee, Jeong Wook Kang, Heejin Kim, Dong Jin Lee, Jin Hwan Kim, Il Seok Park","doi":"10.21053/ceo.2023.00014","DOIUrl":"https://doi.org/10.21053/ceo.2023.00014","url":null,"abstract":"Objective: This study aimed to compare the oncological outcomes of partial and superficial or total parotidectomies for superficial T1 or T2 primary parotid cancers and investigate their prognostic factors and recurrence patterns. Methods: The medical records of 77 patients with T1–2 primary parotid malignancies between May 2003 and March 2022 were retrospectively reviewed. Univariate and multivariate analyses were performed to evaluate the prognostic factors associated with overall survival, disease-free survival, and local and distant recurrences. Results: The average follow-up duration was 70.2 months (range,12–202 months). The 5-year overall and disease-free survival rates were 88.7% and 77.1%, respectively. Twenty-two patients underwent partial parotidectomy, and 55 underwent superficial or total parotidectomy. There were no significant differences in the disease recurrence ( p =0.320) and mortality rates ( p =0.884) of the partial and superficial or total parotidectomy groups. The mean duration of surgery was shorter and the overall complication rates were significantly lower for the partial group than for the superficial or total parotidectomy group ( p =0.049). Sixteen cases of recurrence occurred during the study period (20.8%). Univariate analyses showed that high-grade tumors ( p =0.006), lymphovascular invasion ( p =0.046), and regional lymph node metastasis ( p =0.010) were significant risk factors for disease recurrence. Multivariate analysis identified regional lymph node metastasis as an independent prognostic factor for disease recurrence ( p =0.027), and lymphovascular invasion as an independent prognostic factor for overall survival ( p =0.033). Conclusions: The conservative surgical approach of partial parotidectomy can yield oncologic outcomes comparable to superficial or total parotidectomies under careful patient","PeriodicalId":10318,"journal":{"name":"Clinical and Experimental Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139157474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of differences in nasal shapes and degree of changes with pairing analysis. 通过配对分析,分析鼻形的差异和变化程度。
IF 3 3区 医学
Clinical and Experimental Otorhinolaryngology Pub Date : 2023-12-08 DOI: 10.21053/ceo.2023.01137
Younghac Kim, Joo Hyun Park, Minhae Park, Eunkyu Lee, Sang Duk Hong, Yong Gi Jung, Gwanghui Ryu, Hyo Yeol Kim
{"title":"Analysis of differences in nasal shapes and degree of changes with pairing analysis.","authors":"Younghac Kim, Joo Hyun Park, Minhae Park, Eunkyu Lee, Sang Duk Hong, Yong Gi Jung, Gwanghui Ryu, Hyo Yeol Kim","doi":"10.21053/ceo.2023.01137","DOIUrl":"https://doi.org/10.21053/ceo.2023.01137","url":null,"abstract":"This study aimed to analyze the differences in aging nasal morphometry and the degree of changes within an individual over at least ten-year period by pairing previous and recent three-dimensional reconstructed computed tomography (CT) images.","PeriodicalId":10318,"journal":{"name":"Clinical and Experimental Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138556177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Music-Based Auditory Training on Hearing-Impaired Elderly with Mild Cognitive Impairment. 音乐听觉训练对患有轻度认知障碍的听力受损老人的影响
IF 3 3区 医学
Clinical and Experimental Otorhinolaryngology Pub Date : 2023-12-08 DOI: 10.21053/ceo.2023.00815
Sihun Park, Kyoung Ho Park, Woojae Han
{"title":"The Effects of Music-Based Auditory Training on Hearing-Impaired Elderly with Mild Cognitive Impairment.","authors":"Sihun Park, Kyoung Ho Park, Woojae Han","doi":"10.21053/ceo.2023.00815","DOIUrl":"https://doi.org/10.21053/ceo.2023.00815","url":null,"abstract":"The present study identifies the effect of music-based auditory training on the elderly with hearing loss and decreased cognitive ability, common conditions in the older population.","PeriodicalId":10318,"journal":{"name":"Clinical and Experimental Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138556021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cognitive screening and hearing assessment in patients with chronic tinnitus 慢性耳鸣患者的认知筛查和听力评估
3区 医学
Clinical and Experimental Otorhinolaryngology Pub Date : 2023-11-13 DOI: 10.21053/ceo.2023.00808
Alberto Bernal-Robledano, Patricia Perez-Carpena, Dimitris Kikidis, Birgit Mazurek, Stefan Schoisswohl, Susanne Staudinger, Berthold Langguth, Winfried Schlee, Jose Antonio Lopez-Escamez
{"title":"Cognitive screening and hearing assessment in patients with chronic tinnitus","authors":"Alberto Bernal-Robledano, Patricia Perez-Carpena, Dimitris Kikidis, Birgit Mazurek, Stefan Schoisswohl, Susanne Staudinger, Berthold Langguth, Winfried Schlee, Jose Antonio Lopez-Escamez","doi":"10.21053/ceo.2023.00808","DOIUrl":"https://doi.org/10.21053/ceo.2023.00808","url":null,"abstract":"Objective: The study aims to assess the relationship between tinnitus and hyperacusis with cognitive impairment as indicated by the Montreal Cognitive Assessment (MoCA) tool.Methods: A multicentre cross-sectional study including individuals with chronic tinnitus from the","PeriodicalId":10318,"journal":{"name":"Clinical and Experimental Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136281427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscope-Assisted Hairline Approach for Head and Neck Masses: A Review. 内窥镜辅助发际入路治疗头颈部肿块:综述。
IF 3 3区 医学
Clinical and Experimental Otorhinolaryngology Pub Date : 2023-11-01 Epub Date: 2023-07-31 DOI: 10.21053/ceo.2022.01634
Min Seok Song, Seung Hoon Woo
{"title":"Endoscope-Assisted Hairline Approach for Head and Neck Masses: A Review.","authors":"Min Seok Song, Seung Hoon Woo","doi":"10.21053/ceo.2022.01634","DOIUrl":"10.21053/ceo.2022.01634","url":null,"abstract":"Conventional surgery via a transcervical incision is indicated for treating certain tumors in the head and neck. However, it can cause multiple problems, including scars and cosmetic issues. The endoscope-assisted hairline approach, which replaces conventional surgical procedures, is increasing in use due to excellent cosmetic and functional outcomes. However, given its complex anatomical intricacy, the endoscope-assisted hairline technique is not commonly used for head and neck surgery. The hairline surgical approach evolved with changing disease conditions and recent innovations in surgical instruments. This review article discusses endoscope-assisted hairline approaches for resecting head and neck masses as well as the surgical procedure and postoperative clinical outcomes.","PeriodicalId":10318,"journal":{"name":"Clinical and Experimental Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10710923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9930933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Olfactory System: Basic Anatomy and Physiology for General Otorhinolaryngologists. 嗅觉系统:普通耳鼻喉科医生的基本解剖学和生理学。
IF 3 3区 医学
Clinical and Experimental Otorhinolaryngology Pub Date : 2023-11-01 Epub Date: 2023-09-04 DOI: 10.21053/ceo.2023.00185
Sun A Han, Jin Kook Kim, Do-Yeon Cho, Zara M Patel, Chae-Seo Rhee
{"title":"The Olfactory System: Basic Anatomy and Physiology for General Otorhinolaryngologists.","authors":"Sun A Han, Jin Kook Kim, Do-Yeon Cho, Zara M Patel, Chae-Seo Rhee","doi":"10.21053/ceo.2023.00185","DOIUrl":"10.21053/ceo.2023.00185","url":null,"abstract":"<p><p>Olfaction is one of the five basic human senses, and it is known to be one of the most primitive senses. The sense of olfaction may have been critical for human survival in prehistoric society, and although many believe its importance has diminished over time, it continues to have an impact on human interaction, bonding, and propagation of the species. Even if we are unaware of it, the sense of smell greatly affects our lives and is closely related to overall quality of life and health. Nonetheless, olfaction has been neglected from a scientific perspective compared to other senses. However, olfaction has recently received substantial attention since the loss of smell and taste has been noted as a key symptom of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Studies investigating olfaction loss in association with coronavirus disease 2019 (COVID-19) have revealed that olfactory dysfunction can be both conductive and sensorineural, possibly causing structural changes in the brain. Olfactory training is an effective treatment for olfactory dysfunction, suggesting the reorganization of neural associations. A reduced ability to smell may also alert suspicion for neurodegenerative or psychiatric disorders. Here, we summarize the basic knowledge that we, as otorhinolaryngologists, should have about the sense of smell and the peripheral and central olfactory pathways for managing and helping patients with olfactory dysfunction.</p>","PeriodicalId":10318,"journal":{"name":"Clinical and Experimental Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10710919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10161183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pathophysiological Mechanisms Underlying Unilateral Vocal Fold Paralysis in Female Patients: An Ultrasonographic Study. 女性患者单侧声带麻痹的病理生理机制:一项超声研究。
IF 3 3区 医学
Clinical and Experimental Otorhinolaryngology Pub Date : 2023-11-01 Epub Date: 2023-10-16 DOI: 10.21053/ceo.2023.01046
Yi-An Lu, Yun-Chen Tsai, Wan-Ni Lin, Yu-Cheng Pei, Tuan-Jen Fang
{"title":"Pathophysiological Mechanisms Underlying Unilateral Vocal Fold Paralysis in Female Patients: An Ultrasonographic Study.","authors":"Yi-An Lu, Yun-Chen Tsai, Wan-Ni Lin, Yu-Cheng Pei, Tuan-Jen Fang","doi":"10.21053/ceo.2023.01046","DOIUrl":"10.21053/ceo.2023.01046","url":null,"abstract":"<p><strong>Objectives: </strong>Laryngeal ultrasonography (LUS) has been suggested as an alternative diagnostic tool for unilateral vocal fold paralysis (UVFP). The present study applied LUS and quantitative laryngeal electromyography (LEMG) in female UVFP patients to investigate the pathophysiologic mechanisms of UVFP.</p><p><strong>Methods: </strong>In this cross-sectional study, vocal fold (VF) length parameters included resting and phonating VF length measured using B-mode LUS, and color Doppler vibrating length (CDVL) measured using the color Doppler mode.</p><p><strong>Results: </strong>Forty female patients with UVFP were enrolled, among whom 11 and 29 were assigned to the thyroarytenoid (TA) muscle+cricothyroid (CT) muscle group (with CT involvement) and the TA (without CT involvement) group, respectively. In the TA group, the turn frequency in thyroarytenoid-lateral cricoarytenoid (TA-LCA) on the paralyzed side, as observed through LEMG, correlated with the VF length during the resting phase (R=0.368, P=0.050) and CDVL values (R=0.627, P=0.000) on the paralyzed side. In the TA+CT group, the turn ratio in the CT muscle correlated with the normalized phonatory vocal length change (nPLC; R=0.621, P=0.041) on the paralyzed side.</p><p><strong>Conclusion: </strong>CDVL and nPLC are two parameters that can be utilized to predict the turn frequencies of TA-LCA in UVFP cases without CT involvement, and the turn ratio of CT in cases of UVFP with CT involvement, respectively. The findings suggest that LUS, as a noninvasive tool, can serve as an alternative method for assessing the severity of laryngeal nerve injury and offer valuable insights into the pathophysiology of UVFP.</p>","PeriodicalId":10318,"journal":{"name":"Clinical and Experimental Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10710921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49674959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lack of Correlation of Sinonasal and Otologic Reported Symptoms With Objective Measurements Among Patients With Primary Ciliary Dyskinesia: An International Study. 原发性纤毛运动障碍患者鼻窦和耳科症状与客观测量缺乏相关性:一项国际研究
IF 3 3区 医学
Clinical and Experimental Otorhinolaryngology Pub Date : 2023-11-01 Epub Date: 2023-11-17 DOI: 10.21053/ceo.2023.01130
Yin Ting Lam, Jean-François Papon, Mihaela Alexandru, Andreas Anagiotos, Miguel Armengot, Mieke Boon, Andrea Burgess, Nathalie Caversaccio, Suzanne Crowley, Sinan Ahmed D Dheyauldeen, Nagehan Emiralioglu, Ela Erdem, Christine van Gogh, Yasemin Gokdemir, Onder Gunaydın, Eric G Haarman, Amanda Harris, Isolde Hayn, Hasnaa Ismail-Koch, Bulent Karadag, Céline Kempeneers, Sookyung Kim, Natalie Lorent, Ugur Ozcelik, Charlotte Pioch, Anne-Lise Ml Poirrier, Ana Reula, Jobst Roehmel, Panayiotis Yiallouros, Myrofora Goutaki
{"title":"Lack of Correlation of Sinonasal and Otologic Reported Symptoms With Objective Measurements Among Patients With Primary Ciliary Dyskinesia: An International Study.","authors":"Yin Ting Lam, Jean-François Papon, Mihaela Alexandru, Andreas Anagiotos, Miguel Armengot, Mieke Boon, Andrea Burgess, Nathalie Caversaccio, Suzanne Crowley, Sinan Ahmed D Dheyauldeen, Nagehan Emiralioglu, Ela Erdem, Christine van Gogh, Yasemin Gokdemir, Onder Gunaydın, Eric G Haarman, Amanda Harris, Isolde Hayn, Hasnaa Ismail-Koch, Bulent Karadag, Céline Kempeneers, Sookyung Kim, Natalie Lorent, Ugur Ozcelik, Charlotte Pioch, Anne-Lise Ml Poirrier, Ana Reula, Jobst Roehmel, Panayiotis Yiallouros, Myrofora Goutaki","doi":"10.21053/ceo.2023.01130","DOIUrl":"10.21053/ceo.2023.01130","url":null,"abstract":"","PeriodicalId":10318,"journal":{"name":"Clinical and Experimental Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10710920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138497900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differences in Clinical and Immunological Characteristics According to the Various Criteria for Tissue Eosinophilia in Chronic Rhinosinusitis With Nasal Polyps. 慢性鼻窦炎伴鼻息肉组织嗜酸性粒细胞增多不同诊断标准的临床及免疫学特征差异
IF 3 3区 医学
Clinical and Experimental Otorhinolaryngology Pub Date : 2023-11-01 Epub Date: 2023-08-23 DOI: 10.21053/ceo.2023.00542
Seung Koo Yang, Jeong-Whun Kim, Tae-Bin Won, Chae-Seo Rhee, Yeon Bi Han, Sung-Woo Cho
{"title":"Differences in Clinical and Immunological Characteristics According to the Various Criteria for Tissue Eosinophilia in Chronic Rhinosinusitis With Nasal Polyps.","authors":"Seung Koo Yang, Jeong-Whun Kim, Tae-Bin Won, Chae-Seo Rhee, Yeon Bi Han, Sung-Woo Cho","doi":"10.21053/ceo.2023.00542","DOIUrl":"10.21053/ceo.2023.00542","url":null,"abstract":"<p><strong>Objectives: </strong>Several criteria exist for classifying chronic rhinosinusitis with nasal polyps (CRSwNP) as eosinophilic or non-eosinophilic. This study attempted to evaluate several criteria for defining eosinophilic CRSwNP from clinical and immunological perspectives.</p><p><strong>Methods: </strong>A cohort of 84 patients (73 patients with CRSwNP and 11 control patients) was retrospectively analyzed. Patients were divided into eosinophilic and non-eosinophilic CRSwNP based on four different criteria: eosinophils (EOS) accounting for more than 20% of the total inflammatory cells; ≥70 EOS per high-power field (HPF); >55 EOS/HPF; and ≥10 EOS/HPF. Preoperative clinical characteristics, the immunological profiles of 14 cytokines from nasal tissue, and postoperative outcomes were compared between eosinophilic and non-eosinophilic CRSwNP based on each criterion. These criteria were immunologically validated by using 14 cytokines to predict the performance of tissue eosinophilia with a random forest model.</p><p><strong>Results: </strong>Patients with eosinophilic CRSwNP were significantly older when the criterion of ≥10 EOS/HPF or EOS >20% was used. The number of patients with aspirin intolerance was significantly higher in eosinophilic CRSwNP based on the criterion of EOS >20%. From an immunological perspective, non-type 2 inflammatory cytokines were significantly higher in non-eosinophilic CRSwNP with the criterion of EOS >20% of the total inflammatory cells. In addition, the criterion of EOS >20% of the total inflammatory cells resulted in the best prediction of eosinophilic CRSwNP, with an accuracy of 88.10% and area under the curve of 0.94.</p><p><strong>Conclusion: </strong>Clinical and immunological characteristics were different between eosinophilic and non-eosinophilic CRSwNP depending on a variety of criteria, and the.</p><p><strong>Results: </strong>of this study should be taken into account when choosing the criterion for defining eosinophilic CRSwNP and interpreting the data accordingly.</p>","PeriodicalId":10318,"journal":{"name":"Clinical and Experimental Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10710925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10484912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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