RSC Advances最新文献

{"title":"Engineering a GelMA–dECM-based 3D bioprinted liver fibrosis model: methotrexate-induced functional and molecular validation","authors":"Mrunmayi Gadre and Kirthanashri S. Vasanthan","doi":"10.1039/D5RA05955K","DOIUrl":"10.1039/D5RA05955K","url":null,"abstract":"<p >Three-dimensional (3D) bioprinting represents a cutting-edge advancement in additive manufacturing, offering unprecedented precision in fabricating <em>in vitro</em> models that recapitulate native tissue architecture and function. Here, we present the fabrication of a bioprinted hepatic construct using a composite bioink composed of in-house synthesized gelatin methacryloyl (GelMA), rat liver-derived decellularized extracellular matrix (dECM), and HepG2 cells. GelMA imparted mechanical integrity and biocompatibility, while the liver-specific dECM provided bioactive cues critical for recapitulating the hepatic microenvironment. Constructs were crosslinked using microbial transglutaminase and a photoinitiator to ensure structural stability and shape fidelity. Functional characterization included cytocompatibility assays (MTT, live/dead), metabolic activity assays (albumin and urea secretion), and liver-specific enzyme analysis (LDH, ALT, and ALP), alongside gene expression profiling, all of which confirmed hepatic function within the constructs. This synergy enhances cellular functionality and supports accurate fibrosis modeling for translational research. To establish a fibrosis model, methotrexate (MTX) was introduced, resulting in functional decline and upregulation of fibrosis-associated genes, thereby validating the fibrotic phenotype. This study demonstrates the development of a robust and physiologically relevant 3D bioprinted <em>in vitro</em> platform for modeling MTX-induced liver fibrosis, providing a promising tool for preclinical drug screening and translational research in hepatic disease. This study demonstrates a robust and physiologically relevant 3D bioprinted <em>in vitro</em> model of methotrexate-induced liver fibrosis, offering a valuable platform for translational applications in drug screening and hepatic disease modelling.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 44","pages":" 37012-37026"},"PeriodicalIF":4.6,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MOF modified with a Cu-complex as a novel MOF-based heterogeneous catalyst for the one-pot one-step synthesis of α-aminophosphonates directly from alcohols by a tandem oxidation process","authors":"Sara Sobhani, Alireza Paseban, Roya Jahanshahi and José Miguel Sansano","doi":"10.1039/D5RA06341H","DOIUrl":"10.1039/D5RA06341H","url":null,"abstract":"<p >A metal–organic framework functionalized with a copper complex, named Cu-ISA-MIL-Fe, was fabricated through post-synthetic modification of Fe-MIL-101-NH<small>₂</small> <em>via</em> isatin Schiff-base formation followed by coordination with Cu(OAc)<small>₂</small>. The newly synthesized Cu-ISA-MIL-Fe was characterized by analytical methods, including PXRD, FT-IR, XPS, FESEM, EDS elemental mapping, TEM, and elemental analysis. The similarity of its PXRD pattern with that of Fe-MIL-101-NH<small>₂</small> indicated that the crystalline structure of the MOF in the post-synthetic modification remained intact. FT-IR analysis endorsed the successful construction and functionalization of the MOF. FESEM and TEM images showed that the octahedral morphology of the MOF with an edge length of ∼500 nm was well preserved. XPS elemental survey and EDS elemental mapping confirmed the existence of C, N, O, Cu and Fe, with a uniform distribution throughout the MOF structure. Cu-ISA-MIL-Fe was used as the first MOF-based catalyst for the one-pot one-step synthesis of dialkyl α-aminophosphonates directly from readily available alcohols <em>via</em> a tandem oxidation process. The catalyst showed an extremely high catalytic performance for the selective oxidation of different benzyl alcohols, followed by the condensation of the <em>in situ</em>-prepared benzaldehyde with anilines and alkyl phosphites (tri-ethyl/methyl/<em>iso</em>-propyl and di-<em>iso</em>-propyl phosphites) to produce a variety of dialkyl α-aminophosphonates. This methodology offers a number of merits, including cost-effective operational conditions, efficient and selective product formation in 75–95% yields, reduced reaction times, use of a green solvent, and facile catalyst separation and recyclability. Besides, conducting a simplified one-pot one-step synthetic procedure contributes to step saving, minimizes the procedural complexity and decreases waste production, further enhancing the overall efficiency of the method.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 44","pages":" 36823-36836"},"PeriodicalIF":4.6,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DeepPHSI: attention-driven CNN-LSTM fusion for hyperspectral origin traceability across Pogostemon cablin batches","authors":"Xiaqiong Fan, Yulin Liu, Zihao Zhang, Peijun Zhao, Zhengyan Li, Junjun Zhou, Dandan Zhai, Yi Hu, Peng Li and Hongchao Ji","doi":"10.1039/D5RA06579H","DOIUrl":"10.1039/D5RA06579H","url":null,"abstract":"<p > <em>Pogostemon cablin</em> (<em>P. cablin</em>) is rich in chemical compounds and is extensively utilized in the medicine, food, and fragrance industries. However, factors such as variety, regional ecology, growth conditions, harvest time, and processing methods result in differences in the traits and quality of <em>P. cablin</em> from different origins. The traditional labor-intensive identification methods require a lot of manpower and material resources, and the accuracy of identification is also affected by individual subjectivity. In this study, a deep learning network based on a pixel-level hyperspectral image was constructed to identify <em>P. cablin</em> from different origins, named DeepPHSI. DeepPHSI can be used to distinguish between the three main origins of <em>P. cablin</em> and their stems and leaves from the background. The DeepPHSI model was designed based on convolutional neural and long short-term memory networks. The hyperspectral image data collected under two experimental conditions were used for training and fine-tuning, respectively. Results showed that DeepPHSI can accurately identify the origin of <em>P. cablin</em> under different experimental conditions with transfer learning. The prediction based on DeepPHSI also enabled the fully automated identification of origins and parts, which makes the model suitable for the rapid analysis of large-scale samples. These advantages make DeepPHSI a promising method in hyperspectral applications.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 44","pages":" 37039-37049"},"PeriodicalIF":4.6,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and evaluation of a camphorquinone-derived BTP for minor actinide separation from acidic high-level radioactive liquid waste","authors":"Kumari Anshul, Selvakumar Jayaprakasam, Suneel Gattu, Subramanian Srinivasan and G. Srinivasa Rao","doi":"10.1039/D5RA05245A","DOIUrl":"10.1039/D5RA05245A","url":null,"abstract":"<p >A camphorquinone-derived bis-triazinylpyridine, bis-2,6-(5,6,7,8-tetrahydro-5,9,9-trimethyl-5,8-methano-1,2,4-benzotriazin-3-yl)pyridine (CA-BTP), was synthesised and systematically evaluated for the selective separation of minor actinides (MA: <small>²⁴¹</small>Am and <small>¹⁵⁴</small>Eu) from acidic high-level radioactive liquid waste (HLW). The extractant was purified by gradient polarity chromatography, with structure confirmation <em>via</em> FT-IR, <small>¹</small>H NMR, ESI-MS, and TG-DSC, affirming chemical purity and thermal robustness. Extraction studies revealed excellent solubility and stability in 1-octanol and isodecyl alcohol (IDA), with sharp phase separation and no third-phase formation. Radiotracer experiments using <small>²⁴¹</small>Am and <small>¹⁵⁴</small>Eu demonstrated high selectivity, achieving separation factors (SF<small>_Am/Eu</small>) of 150–280 at 1 M HNO<small>₃</small> using 0.1 M CA-BTP. Mechanistic investigations included acid uptake, nitrate ion dependence, temperature variation, and slope analysis, revealing a 3 : 1 ligand-to-metal stoichiometry and an exothermic extraction process (Δ<em>H</em> = −33.6 to −42.5 kJ mol<small>⁻¹</small>). CA-BTP also showed efficient back-extraction under mild acidic conditions (0.01 M HNO<small>₃</small>), without the need for synergists or complexing agents. These findings position CA-BTP as a robust, scalable, and selective extractant for advanced SANEX-type flowsheets aimed at minor actinide partitioning from chemically similar lanthanides.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 44","pages":" 36808-36822"},"PeriodicalIF":4.6,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficient oxidation of hindered amines to nitroxide radicals with hydrogen peroxide over layered double hydroxide","authors":"Yupeng Zhang, Wensheng Xu, Zefan Liu, Ligong Chen, Xilong Yan, Bowei Wang and Yang Li","doi":"10.1039/D5RA05993C","DOIUrl":"10.1039/D5RA05993C","url":null,"abstract":"<p >Alkoxylation of hindered amine light stabilisers is a common strategy to reduce their basicity and expand their application scope. However, the current catalysts used for preparing the nitroxide radical intermediates are limited by their separation and recycling properties. To address this issue, this study proposes a method for the preparation of hindered amine nitroxide radical intermediates using hydrogen peroxide as the oxidant and layered double hydroxides (LDHs) as heterogeneous catalysts. Excitingly, when using only 5.00 wt% LDHs with a Mg/Al ratio of 3 : 1, both the conversion of the hindered amine and the selectivity towards the corresponding nitroxide radical exceeded 99.9%. Moreover, the catalyst was recyclable and could be reused for more than five cycles without significant loss of its activity. Theoretical calculations and radical trapping experiments revealed that LDHs act as solid bases to promote the decomposition of hydrogen peroxide into reactive oxygen species (ROS), thereby synergistically oxidizing hindered amines to nitroxide radical intermediates. The key influencing factors for the catalytic performance were found to be the types and proportions of metal ions in the LDHs. This study has provided a new pathway for the oxidation of hindered amines to the corresponding nitroxide radicals.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 44","pages":" 36769-36777"},"PeriodicalIF":4.6,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heavy metal adsorption by graphene oxide modified with 5-amino-3(2-thienyl)pyrazole using central composite design/response surface methodology (CCD/RSM)","authors":"Mobina Alimohammady, Mansour Jahangiri, Masoud Salavati-Niasari and Aseel M. Aljeboree","doi":"10.1039/D5RA04106F","DOIUrl":"10.1039/D5RA04106F","url":null,"abstract":"<p >In this study, graphene oxide (GO) was chemically functionalized with 5-amino-3(2-thienyl)pyrazole (5-ATP), introducing oxygen-, nitrogen-, and sulfur-containing groups, to enhance adsorption performance and develop a multifunctional adsorbent (5-ATP-GO) for efficient removal of Cd(<small>II</small>), Hg(<small>II</small>), and As(<small>III</small>) from aqueous solutions. The GO and 5-ATP-GO composites were characterized by Fourier transform infrared spectroscopy, field-emission scanning electron microscopy, thermogravimetric analysis, X-ray diffraction, energy-dispersive X-ray spectroscopy, Brunauer–Emmett–Teller analysis, Raman spectroscopy, and zeta potential analysis. The performance of 5-ATP-GO for heavy metal removal was evaluated by design of experiment to optimize operational parameters and assess adsorption capacity. Central composite design/response surface methodology analysis was applied for the optimization of adsorbing conditions, (<em>i.e.</em>, pH, initial metal ion concentrations, and adsorbent dosage). Furthermore, analysis of variance revealed that quadratic equations well predicted experimental data with an <em>R</em><small>²</small> value of &gt;0.99 and a <em>p</em>-value of &lt;0.05. Experimental optimization variables were a pH of 7.25–8.55, an initial metal ion concentration of 43.45–49.66 mg L<small>⁻¹</small>, and an adsorbent dose of 10–10.50 g L<small>⁻¹</small>. Results showed that most of the adsorption occurred within the first 30 minutes, during which only 0.2 g L<small>⁻¹</small> of 5-ATP-GO successfully removed 79.8% of Hg(<small>II</small>), 86.5% of Cd(<small>II</small>), and 75.1% of As(<small>III</small>) ions from the solution. These rapid kinetics were further supported by high adsorption capacities of 213.5 mg g<small>⁻¹</small> for Hg(<small>II</small>), 280.1 mg g<small>⁻¹</small> for Cd(<small>II</small>), and 450.95 mg g<small>⁻¹</small> for As(<small>III</small>), underscoring the superior uptake potential of 5-ATP-GO toward toxic metal ions. Furthermore, adsorption kinetics and isotherm studies revealed that the data were well fitted to the pseudo-second-order kinetic model and Freundlich isotherm, indicating that the adsorption process follows a heterogeneous chemisorption mechanism. Finally, comparative experiments with pristine GO and other conventional adsorbents confirmed the superior removal efficiency and enhanced performance of the 5-ATP-GO composite.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 44","pages":" 36837-36860"},"PeriodicalIF":4.6,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation of biotemplated Fe3O4 nanoparticles and evaluation of RF-induced heating efficiency for targeted hyperthermia","authors":"Y. Ranjith Kumar, Pragya Trivedi, Avijit Jana, D. Suman and M. Vasundhara","doi":"10.1039/D5RA03372A","DOIUrl":"10.1039/D5RA03372A","url":null,"abstract":"<p >In this study, we report the synthesis of Fe<small>₃</small>O<small>₄</small> nanoparticles (NPs) employing a mild sol–gel synthesis method with Fe-nitrate precursors and egg deutoplasm fluid, a bio-template, as stabilizing agent. The Fe<small>₃</small>O<small>₄</small> NPs were synthesized with varying concentrations of the stabilizing agent to determine the optimal conditions. The synthesized Fe<small>₃</small>O<small>₄</small> NPs were comprehensively characterized to evaluate their structural, morphological, optical, and magnetic properties. The characterization techniques used were X-ray diffraction (XRD), Raman spectroscopy and X-ray photoelectron spectroscopy (XPS), Transmission electron microscopy (TEM), Fourier transform infrared (FTIR) spectroscopy, UV-Visible spectroscopy and Vibrating Sample Magnetometry (VSM). Magnetic measurements were also conducted at room temperature to understand the magnetic behaviour, a crucial property for biomedical applications such as hyperthermia and targeted drug delivery. To explore their potential for hyperthermia applications, the Fe<small>₃</small>O<small>₄</small> NPs were exposed to radio-frequency (RF) for evaluating their heating efficiency. The Fe<small>₃</small>O<small>₄</small> NPs exhibited significant RF absorption, leading to effective thermal conversion and achieving the target hyperthermic temperature of 42 °C, which is essential for cancer treatment. The ability of the synthesized Fe<small>₃</small>O<small>₄</small> NPs to generate localized heat in response to RF energy underscores their potential for precise and controlled hyperthermic therapy. This study highlights the importance of optimizing synthesis conditions to tailor the magnetic properties and heating ability of Fe<small>₃</small>O<small>₄</small> NPs for biomedical applications. The findings demonstrate that bio-templated Fe<small>₃</small>O<small>₄</small> NPs offer a promising approach for targeted cancer therapy by leveraging RF-induced heating for localized and effective treatment.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 44","pages":" 36879-36894"},"PeriodicalIF":4.6,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review on the sulfur ylide-mediated Corey–Chaykovsky reaction: a powerful approach to natural product synthesis","authors":"Ammara, Asim Mansha, Samreen Gul Khan, Ameer Fawad Zahoor, Muhammad Jawwad Saif, Bushra Parveen, Muhammad Athar Saeed, Aijaz Rasool Chaudhry, Ahmad Irfan and Muhammad Abbas","doi":"10.1039/D5RA04921K","DOIUrl":"10.1039/D5RA04921K","url":null,"abstract":"<p >The Corey–Chaykovsky reaction is an efficient transformation in organic syntheses, which enables the construction of 3-membered cores <em>via</em> a sulfur ylide-mediated process. The reaction enables a simple yet versatile strategy to access cyclopropanes, epoxides and aziridines. The resulting cyclic frameworks are significantly valuable for the synthesis of several structurally complex compounds, including numerous natural products and their analogues. This review underscores the importance and utility of the Corey–Chaykovsky reaction towards the total synthesis of several classes of natural products reported since 2020.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 44","pages":" 37125-37151"},"PeriodicalIF":4.6,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of benzimidazoles from o-phenylenediamines with α-keto acids via amino acid catalysis","authors":"Zhenbiao Luo, Mulin Huang, Xiangyong Wang, Xinye Wang, Zhihui Hu, Liang Zhao and Ting Huang","doi":"10.1039/D5RA06371J","DOIUrl":"10.1039/D5RA06371J","url":null,"abstract":"<p >A green and simple method for the synthesis of benzimidazoles by amino acid catalysis of <em>o</em>-phenylenediamines with α-keto acids has been developed. The reaction proceeded smoothly in water under air and metal catalyst-free conditions to obtain 2-substituted benzimidazoles. Furthermore, the method was performed in an open system at room temperature, making the experimental operation very simple and greatly enhancing the accessibility of the method.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 44","pages":" 36803-36807"},"PeriodicalIF":4.6,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spectroscopic signatures of interfacial energy transfer in MoS2-based van der Waals heterostructures under deep-UV excitation","authors":"Tsung-Hsien Lee, Sheng-Lung Chou, Tzu-Ping Huang, Chak-Ming Liu, Chih-Hao Chin, Meng-Yeh Lin, Hui-Fen Chen and Yu-Jong Wu","doi":"10.1039/D5RA04686F","DOIUrl":"10.1039/D5RA04686F","url":null,"abstract":"<p >We report a comprehensive photoluminescence (PL) and photoluminescence excitation (PLE) study of monolayer MoS<small>₂</small> and its van der Waals heterostructures with hBN and graphene under deep-ultraviolet (DUV) excitation. Using synchrotron-based VUV/UV spectroscopy, we reveal that while pristine MoS<small>₂</small> exhibits only A-exciton emission at ∼660 nm under visible excitation, broadband near-infrared emission (750–900 nm) emerges at cryogenic temperatures under DUV excitation in MoS<small>₂</small>/hBN and MoS<small>₂</small>/graphene heterostructures. This emission indicates a nonlocal excitation–emission mechanism facilitated by interfacial energy transfer from the UV-absorbing layers. In MoS<small>₂</small>/hBN, a broad UV band near 350 nm also appears under 200 nm excitation and is attributed to impurity-related defect luminescence in hBN. The interfacial processes are governed by temperature-sensitive radiative channels involving defect-bound states or localized excitons in MoS<small>₂</small>. Our results highlight the crucial role of interlayer coupling and spectral sensitization in enabling new radiative pathways in 2D heterostructures, offering novel strategies for tailoring light emission in layered optoelectronic systems.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 44","pages":" 37183-37193"},"PeriodicalIF":4.6,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}