硫酰基介导的Corey-Chaykovsky反应：天然产物合成的有力途径

IF 4.6 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

RSC Advances Pub Date : 2025-10-06 DOI:10.1039/D5RA04921K

Ammara, Asim Mansha, Samreen Gul Khan, Ameer Fawad Zahoor, Muhammad Jawwad Saif, Bushra Parveen, Muhammad Athar Saeed, Aijaz Rasool Chaudhry, Ahmad Irfan and Muhammad Abbas

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引用次数: 0

摘要

Corey-Chaykovsky反应是有机合成中一种高效的转化反应，它可以通过硫酰化介导的过程构建3元核心。该反应使一个简单而通用的策略，以获得环丙烷，环氧化物和叠氮醚。所得到的环状框架对于合成几种结构复杂的化合物，包括许多天然产物及其类似物具有重要价值。本综述强调了自2020年以来报道的Corey-Chaykovsky反应对几种天然产物全合成的重要性和实用性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

A review on the sulfur ylide-mediated Corey–Chaykovsky reaction: a powerful approach to natural product synthesis

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A review on the sulfur ylide-mediated Corey–Chaykovsky reaction: a powerful approach to natural product synthesis

The Corey–Chaykovsky reaction is an efficient transformation in organic syntheses, which enables the construction of 3-membered cores via a sulfur ylide-mediated process. The reaction enables a simple yet versatile strategy to access cyclopropanes, epoxides and aziridines. The resulting cyclic frameworks are significantly valuable for the synthesis of several structurally complex compounds, including numerous natural products and their analogues. This review underscores the importance and utility of the Corey–Chaykovsky reaction towards the total synthesis of several classes of natural products reported since 2020.

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来源期刊

RSC Advances chemical sciences-

CiteScore

7.50

自引率

2.60%

发文量

3116

审稿时长

1.6 months

期刊介绍： An international, peer-reviewed journal covering all of the chemical sciences, including multidisciplinary and emerging areas. RSC Advances is a gold open access journal allowing researchers free access to research articles, and offering an affordable open access publishing option for authors around the world.