RSC Advances最新文献

{"title":"Green removal and waste valorization of ciprofloxacin from water using zinc–iron LDH–chia seed biocomposites: integrated adsorption, computational modeling, and electrochemical conversion","authors":"Samar M. Mahgoub, Hassan A. Rudayni, Ahmed A. Allam, Sulaiman A. Alsalamah, Asmaa Elrafey, Rania Abdelazeem, Amna A. Kotp, Mahmoud M. Abdelsatar, Rami Shafi and Rehab Mahmoud","doi":"10.1039/D5RA06018D","DOIUrl":"https://doi.org/10.1039/D5RA06018D","url":null,"abstract":"<p >The contamination of water with pharmaceuticals like ciprofloxacin (CFX) presents serious environmental challenges, necessitating efficient and sustainable treatment methods. This study introduces a novel green adsorbent based on zinc–iron layered double hydroxides (Zn–Fe LDH) encapsulated with chia seed mucilage for effective CFX removal. The synthesized Zn–Fe LDH/chia seed composite demonstrated exceptional efficacy, achieving 98.5% removal of CFX from water at pH 8. The adsorption process was best described by the Langmuir model, revealing a remarkably high maximum capacity of 850.05 mg g<small>⁻¹</small>. Thermodynamic studies confirmed the process was spontaneous and exothermic. The composite exhibited excellent regenerability, retaining 85.2% of its initial adsorption capacity after five consecutive cycles using a simple 0.1 M NaOH eluent. The composite proved to be cost-effective, with a synthesis cost of $2.033 per gram. Quantum chemical modeling revealed strong interactions (Δ<em>E</em><small>_int</small> = −32.5 kcal mol<small>⁻¹</small>) between CFX and the chia-modified LDH surface, validating the experimental results. Furthermore, the material exhibited excellent potential for waste valorization, showing current densities of 18.71 mA cm<small>⁻²</small> and 15.45 mA cm<small>⁻²</small> for methanol electro-oxidation before and after adsorption, respectively. A semi-pilot filtration system successfully demonstrated practical scalability, achieving &gt;80% CFX removal from raw wastewater within 20 minutes. Greenness assessment tools (AGREEprep, BAGI, RGB12) confirmed the eco-friendly nature of the entire process, supporting circular economy goals through this low-cost, dual-function material design.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 45","pages":" 37705-37726"},"PeriodicalIF":4.6,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra06018d?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145255805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-pot ultrasound synthesis of polyaniline–ZnO and its synergistic effect on microbial activity","authors":"Kalpana N. Handore, Sumit B. Sharma and Vasant V. Chabukswar","doi":"10.1039/D5RA04461H","DOIUrl":"https://doi.org/10.1039/D5RA04461H","url":null,"abstract":"<p >In this investigation, an eco-friendly ultrasonic-assisted green synthesis was employed to synthesize a polyaniline–zinc oxide (PANI–ZnO) nanocomposite with particle sizes ranging from 50 to 60 nm. Zinc oxide (ZnO) nanoparticles were synthesised using a low-cost coprecipitation approach, and the PANI–ZnO nanocomposite was formed <em>in situ</em> using an ultrasound, single-step oxidative polymerisation process. This approach promoted a uniform dispersion of the ZnO nanoparticles inside the polyaniline matrix, which improved the physicochemical interactions between the organic and inorganic phases. The structural, morphological, thermal, optical, and electrical properties of the nanocomposite were thoroughly investigated using ultraviolet-visible (UV-vis) spectroscopy, Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), thermogravimetric analysis (TGA), and electrical conductivity measurements. UV-vis and FTIR analyses showed the nanocomposite's effective production and interaction with ZnO and PANI functional groups. SEM scans revealed that the ZnO nanoparticles were uniformly dispersed throughout the PANI matrix, with no agglomeration. XRD patterns demonstrated that the crystalline character of ZnO was preserved within the composite, while TGA results indicated that the nanocomposite was more thermally stable than pure PANI. Electrical conductivity experiments revealed that the addition of ZnO altered charge transport capabilities, increasing the composite's suitability for electronic applications. Furthermore, the antibacterial activity of the PANI–ZnO nanocomposite was tested against <em>Escherichia coli</em> (<em>E. coli</em>), <em>Staphylococcus aureus</em> (<em>S. aureus</em>), and <em>Salmonella typhi</em> (<em>S. typhi</em>). The nanocomposite exhibited better antibacterial activity against <em>E. coli</em> and <em>S. aureus</em> but reduced activity against <em>S. typhi</em>. The observed antibacterial behaviour was due to the synergistic interaction between the ZnO nanoparticles and the PANI matrix, which resulted in improved disruption of bacterial cell membranes. Overall, the PANI–ZnO nanocomposite synthesised <em>via</em> this green, ultrasonic technique showed remarkable multifunctional capabilities, making it a feasible option for applications in antimicrobial materials, sensors, and electronic devices.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 45","pages":" 37856-37864"},"PeriodicalIF":4.6,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra04461h?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145256034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metal-free access to 4-indolyl coumarin from coumarin 3-carboxylic acid and indole via a Michael addition-decarboxylation and dehydrogenation protocol: a photo-physical study and utility as an invisible ink","authors":"Sourav Chakraborty, Arghyadeep Bhattachrjyya, Bhaswati Paul, Barnali Das, Ramalingam Natarajan and Swapan Majumdar","doi":"10.1039/D5RA05851A","DOIUrl":"https://doi.org/10.1039/D5RA05851A","url":null,"abstract":"<p >Herein, on water tandem Michael addition-decarboxylation of coumarin-3-carboxylic acids with indoles under catalysis of Amberlite IR120 afforded 4-indolyl 3,4-dihydrocoumarin. The process was extended to the synthesis of 4-indolyl coumarin derivatives upon oxidation using an organic oxidant. The wide substrate scope, high product yields, catalytic recyclability and large-scale preparation of intermediates are the noteworthy features of this methodology. This two-step process provides better yields of 4-indole-substituted coumarins as compared to the corresponding single-step palladium-catalyzed cross-coupling reactions. We also report herein for the first time that the indole-coumarin hybrid can be used as a thermal- and moisture-resistant invisible ink.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 45","pages":" 37888-37898"},"PeriodicalIF":4.6,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra05851a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145255801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanocomposites based on a multicomponent polyurethane/poly(hydroxypropyl methacrylate) polymer matrix and nanofiller hydroxy-POSS as potential noise and vibration damping materials","authors":"Lyudmyla Karabanova, Nataliia Babkina, Dmytro Klimchuk and Lyubov Honcharova","doi":"10.1039/D5RA03574K","DOIUrl":"https://doi.org/10.1039/D5RA03574K","url":null,"abstract":"<p >Nanocomposites based on multicomponent polymer matrices, consisting of polyurethane and poly(hydroxypropyl methacrylate) and representing a semi-interpenetrating polymer network, and nanofiller hydroxy-POSS were synthesized, and the thermodynamic parameters of interactions in the system, the dynamic-mechanical properties and the morphology were investigated. The free energy (Gibbs energy) of polyurethane and poly(hydroxypropyl methacrylate) mixing was calculated depending on the hydroxy-POSS content in the nanocomposites. It was shown that polyurethane and poly(hydroxypropyl methacrylate) are thermodynamically incompatible. Introduction of a hydroxy-POSS nanofiller leads to an increase in the thermodynamic incompatibility between polyurethane and poly(hydroxypropyl methacrylate). Dynamic mechanical analysis has shown that for the nanocomposites, there is one maximum of the mechanical loss (tg <em>δ</em>), which is the result of forced phase compatibility and the existence of a large proportion of interphase layers in the systems. This broad maximum of tan <em>δ</em> covers the temperature range from 0 to 100 °C and has a rather high intensity. This means that the created nanocomposites have the potential of being used as effective noise-vibration-damping materials.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 45","pages":" 37965-37978"},"PeriodicalIF":4.6,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra03574k?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145256062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of CO2 substitution for N2 on the combustion characteristics and kinetics of oil shale under oxy-fuel conditions","authors":"Qi Liu, Qing Wang, Zhichao Wang and Huishuang Di","doi":"10.1039/D5RA05471K","DOIUrl":"https://doi.org/10.1039/D5RA05471K","url":null,"abstract":"<p >Oxy-fuel combustion is recognized as a near-zero-emission technology and an effective route for large-scale CO<small>₂</small> capture. Using TGA-DSC-MS, this study performed non-isothermal combustion tests on Fushun and Changji oil shales in two atmospheres—21%O<small>₂</small>/79%N<small>₂</small> and 21%O<small>₂</small>/79%CO<small>₂</small>—to systematically assess how replacing N<small>₂</small> with CO<small>₂</small> alters combustion behavior and kinetic parameters. Across 0–1000 °C, the CO<small>₂</small>-containing atmosphere exhibits weaker momentum diffusion, heat transfer, and mass transport, which elevates ignition and burnout temperatures for both shales, delays the overall combustion process, and diminishes performance. The ignition and burnout stages of both materials are jointly governed by heating rate and CO<small>₂</small> concentration. Furthermore, the addition of CO<small>₂</small> causes the decomposition process of carbonates in Changji oil shale to shift from a single weight loss peak to three distinct peaks. Vyazovkin's advanced isoconversional kinetic analysis indicates that, as the combustion reaction progresses, the activation energy of both oil shales first decreases and then increases. In CO<small>₂</small>-enriched atmospheres, higher activation energy is required to complete the combustion process. The significant variation in combustion activation energy with conversion rate under both atmospheres demonstrates that the combustion of organic matter involves multiple parallel or sequential reactions, with the kinetic mechanism dynamically changing.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 45","pages":" 37937-37950"},"PeriodicalIF":4.6,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra05471k?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145255803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green diesel production via deoxygenation of triolein catalysed by nickel-molybdenum-supported catalysts","authors":"G. AbdulKareem-Alsultan, Nur Athirah Adzahar, G. Omer-Alsultan, N. Asikin-Mijan, H. V. Lee, Tonni Agustiono Kurniawan and Y. H. Taufiq-Yap","doi":"10.1039/D5RA04601G","DOIUrl":"https://doi.org/10.1039/D5RA04601G","url":null,"abstract":"<p >The deoxygenation of triolein into hydrocarbons has been carried out over NiO/CeO<small>₂</small>, MoO<small>₂</small>/CeO<small>₂</small> and NiO–MoO<small>₂</small>/CeO<small>₂</small> under partial vacuum and solvent-free conditions. NiO–MoO<small>₂</small>/CeO<small>₂</small> exhibited a remarkably higher yield of hydrocarbons (65%) and <em>n</em>-C<small>₁₇</small> selectivity (37%) in comparison with single metal oxide–supported CeO<small>₂</small> catalysts. Interestingly, the rich acid–base character and excellent synergistic effect between Ni–Mo and CeO<small>₂</small> positively impacted the deoxygenation reaction while suppressing the cracking reaction. The addition of Ni- and Mo-rich species deteriorated the deoxygenation activity. The highest hydrocarbon yield (77%) and <em>n</em>-C<small>₁₇</small> selectivity (58%) can be achieved at a reaction temperature of 340 °C, 1 h of reaction time, 15 wt% of catalyst loading and 10 mbar of reaction pressure under partial vacuum conditions. Based on catalyst support comparison (CeO<small>₂</small>, Al<small>₂</small>O<small>₃</small>, SiO<small>₂</small>, and ZSM-5), CeO<small>₂</small> is a promising catalyst support for the production of diesel-rich fuels <em>via</em> solvent-free catalytic deoxygenation of triolein.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 45","pages":" 37876-37887"},"PeriodicalIF":4.6,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra04601g?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145256033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review of epoxy vitrimer-based thermally conductive composites","authors":"Huimei Yao, Xuan Xu, Zipeng Chen, Kai Li, Tao Wang, Shenghua Pei, Jiaojiao Fu and Jiaxin Wang","doi":"10.1039/D5RA05874K","DOIUrl":"https://doi.org/10.1039/D5RA05874K","url":null,"abstract":"<p >Driven by advancements in integrated and high-power electronic devices, polymer composites featuring high thermal conductivity (TC), recyclability, and dynamic functionalization have emerged as a focal point in thermal management research. Epoxy vitrimer (EV), owing to its covalent adaptable network (CAN), which enables self-healing, recyclability, and network reconstruction, presents a novel paradigm for designing high-performance thermally conductive composites (TCCs). This review systematically reviews the synthesis strategies, exchange mechanisms, and properties of epoxy vitrimer-based thermally conductive composites (EVTCCs) across diverse CAN architectures (<em>e.g.</em>, ester, disulfide, imine, <em>etc.</em>), while highlighting key advancements and future directions in this evolving field.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 45","pages":" 37908-37925"},"PeriodicalIF":4.6,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra05874k?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145256044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrospun poly(ε-caprolactone)/silver nanoparticle nanofibrous scaffolds with antibacterial activity for wound-dressing applications","authors":"Ali L. Alfalluji, Qasim Shakir Kadhim and Ausama AbedAlkhadum Mahdi","doi":"10.1039/D5RA06746D","DOIUrl":"https://doi.org/10.1039/D5RA06746D","url":null,"abstract":"<p >Silver nanoparticle (AgNP)-based nanofibers are widely used in biomedical applications for their broad-spectrum activity and biocompatibility. This study aims to biofabricate and characterize electrospun polycaprolactone (PCL) nanofibers loaded with biosynthesized AgNPs, with the goal of evaluating their structural properties and antibacterial effectiveness for potential use in antibacterial wound-dressing applications. The biosynthesis of AgNPs was achieved using an aqueous extract of Piper nigrum leaves. Nanocomposite membranes at different AgNP concentrations (0.04, 0.4, and 1 wt%) were prepared to investigate their physicochemical and antibacterial properties. Morphological characterization confirmed bead-free, continuous fiber formation, with reduced fiber diameters upon increasing AgNP content. AFM results revealed enhanced surface roughness. FTIR spectra indicated improved hydrophilicity and successful chemical incorporation of AgNPs. Mechanical testing demonstrated increased tensile strength at 0.4 wt% AgNPs, followed by a decline due to nanoparticle agglomeration at 1 wt%. Contact angle measurements confirmed a significant shift toward hydrophilicity with higher AgNP concentrations. Antibacterial assays revealed strong inhibition against <em>Escherichia coli</em> and <em>Staphylococcus aureus</em>, with the 1 wt% AgNP scaffold producing the most prominent zones of inhibition. These results suggest that PCL-AgNP nanofibers are a promising antibacterial platform for biomedical applications, particularly as infection–preventive wound-dressing materials.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 45","pages":" 37899-37907"},"PeriodicalIF":4.6,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra06746d?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145256061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overcoming colorectal cancer and cancer stem cell resistance with photodynamic therapy: new frontiers in oncology","authors":"Mehak Zahra, Umal Baneen Zahra, Heidi Abrahamse and Blassan P. George","doi":"10.1039/D5RA07380D","DOIUrl":"https://doi.org/10.1039/D5RA07380D","url":null,"abstract":"<p >Colorectal cancer (CRC) is a major global health issue characterized by abnormal cell growth leading to high morbidity and mortality rates. While conventional treatments like chemotherapy and surgery exist, they often fall short due to severe side effects and the emergence of treatment resistance, particularly from cancer stem cells (CSCs). These CSCs contribute to tumor initiation, progression, and recurrence, posing challenges for effective management. Photodynamic therapy (PDT) offers a promising alternative, leveraging light-activated photosensitizers (PSs) to selectively target and destroy tumor cells while minimizing damage to healthy tissue. Recent advancements in PDT, including the use of nanoparticles (NPs) and novel PSs, enhance its efficacy against CRC and CSCs. Preclinical studies have demonstrated PDT ability to induce apoptosis and inhibit tumor growth in various models, highlighting its potential as a therapeutic strategy. Additionally, combining PDT with immune checkpoint inhibitors may further improve treatment outcomes by activating robust immune responses. This review discusses the mechanisms of resistance in CRC, the role of CSCs, and the evolving landscape of PDT, emphasizing the need for continued research to optimize combination therapies for enhanced efficacy against colorectal cancer.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 45","pages":" 37833-37855"},"PeriodicalIF":4.6,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra07380d?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145255960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EMA-based fitting of optical transitions in CoPc: insights into carrier dynamics","authors":"Nawal K. Almaymoni, Shoug M. Alghamdi, Ahmed S. Abdo, Wafaa B. Elsharkawy, Taghreed Alsulami, Maged S. Al-Fakeh, Ayman M. Mostafa and A. Abouelsayed","doi":"10.1039/D5RA06277B","DOIUrl":"https://doi.org/10.1039/D5RA06277B","url":null,"abstract":"<p >Optical measurements have been performed in a wide frequency range between 400 cm<small>⁻¹</small> and 52 000 cm<small>⁻¹</small> on partially oxidized cobalt phthalocyanine (CoPc). The mid-IR band for the electric field E parallel to the stacking axis, centered at about 4008 for [CoPc]<small>⁺</small> ions, respectively, has been discussed in terms of resonance absorption based on the effective medium approximation (EMA) model. The band in the reflectivity and conductivity spectra has been fitted using the normal Lorentz function and the general form of the Maxwell–Garnett equation. Various fitting features, which are explored for free electron metals, are obtained by inserting one Drude term in the Maxwell–Garnett equation, such as the plasma frequency and the time scattering rate. Based on the parameters extracted from fitting the mid-IR band according to the EMA model, we were able to obtain the effective conductivity <em>σ</em><small>_eff</small> (<em>ω</em>) as a function of frequency.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 45","pages":" 37926-37936"},"PeriodicalIF":4.6,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra06277b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145255961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}